Search results for "DAS"
showing 10 items of 4164 documents
Курсъ сравнительной морфологіи индоэвропэйских языковъ: читанъ въ 1909-10 уч. г. въ С-Петербургскомъ Ун-тѣ
1910
Rokraksta litogrāfijas sējums
Heterologous expression of aRauvolfiacDNA encoding strictosidine glucosidase, a biosynthetic key to over 2000 monoterpenoid indole alkaloids
2002
Strictosidine glucosidase (SG) is an enzyme that catalyses the second step in the biosynthesis of various classes of monoterpenoid indole alkaloids. Based on the comparison of cDNA sequences of SG from Catharanthus roseus and raucaffricine glucosidase (RG) from Rauvolfia serpentina, primers for RT-PCR were designed and the cDNA encoding SG was cloned from R. serpentina cell suspension cultures. The active enzyme was expressed in Escherichia coli and purified to homogeneity. Analysis of its deduced amino-acid sequence assigned the SG from R. serpentina to family 1 of glycosyl hydrolases. In contrast to the SG from C. roseus, the enzyme from R. serpentina is predicted to lack an uncleavable N…
Redox intermediates of plant and mammalian peroxidases: a comparative transient-kinetic study of their reactivity toward indole derivatives.
2002
Abstract A comparative study on the reactivity of five indole derivatives (tryptamine, N-acetyltryptamine, tryptophan, melatonin, and serotonin), with the redox intermediates compound I (k2) and compound II (k3) of the plant enzyme horseradish peroxidase (HRP) and the two mammalian enzymes lactoperoxidase (LPO) and myeloperoxidase (MPO), was performed using the sequential-mixing stopped-flow technique. The calculated bimolecular rate constants (k2, k3) revealed substantial differences regarding the oxidizability of the substrates by redox intermediates at pH 7.0 and 25°C. With HRP it was shown that k2 and k3 are mainly determined by the reduction potential (E°′) of the substrate with k2 bei…
1,2,4-Oxadiazole topsentin analogs as staphylococcal biofilm inhibitors targeting the bacterial transpeptidase sortase A
2020
The inhibition or prevention of biofilm formation represents an emerging strategy in the war against antibiotic resistance, interfering with key players in bacterial virulence. This approach includes the inhibition of the catalytic activity of transpeptidase sortase A (Srt A), a membrane enzyme responsible for covalently attaching a wide variety of adhesive matrix molecules to the peptidoglycan cell wall in Gram-positive strains. A new series of seventeen 1,2,4-oxadiazole derivatives was efficiently synthesized and screened as potential new anti-virulence agents. The ability of inhibiting biofilm formation was evaluated against both Gram-positive and Gram-negative pathogens. Remarkably, all…
Anleitung zum Studien der Sanskrit-Sprache
1871
Mācību materiāls studiju vajadzībām ietver skaidrojošu ievadtekstu par sanskritu, sanskrita- vācu vārdnīcu ar atsaucēm uz Rigvēdas tekstu un atsevišķu tulkojošo daļu pie 'Hymnen des Rigvēdas". Manuskripts rokrakstā, datējums nav precīzi zināms.
Inflammatory Response of the Ascidian Ciona intestinalis
2016
Abstract The Ciona intestinalis inflammatory response to several irritants appears to be composed of a complex reaction set. The cellular reactions in the tunic involve hemocyte infiltration, hemocyte and epidermis activities, vacuolization, and cell disruption, while cell products can contribute to form capsule components and/or cause a tunic wound. In this response, the involvement of the pharynx, as the main immune-competent organ, has been disclosed by a lipopolysaccharide challenge that upregulates innate immunity genes and transcription activation genes. The pharynx responds through hemocyte recruitment into the pharynx vessels, enhancement of galectin-like lectins in the serum hemoly…
La información no financiera en el sector público : alternativas, tendencias y oportunidades
2019
In recent years, different non-financial information models have arisen, both in the private and public sectors, trying to complete the traditional financial reports prepared by companies and public administrations. The fundamental objective of these models has been to satisfy the interest of the stakeholders, which goes beyond the numbers included in the balance sheet and the income statement. In the case of the public sector, this is coupled with the discontent and distrust of citizens towards politicians and administrators of institutions, which makes it necessary to emphasize tools and strategies that can improve the transparency and accountability of administrations and restore citizen…
Tratamiento penal del abuso de información privilegiada en el mercado financiero
2012
Se entiende por 'abuso de información privilegiada' la realización de operaciones ventajosas en los mercados financieros utilizando una información no conocida por el público.
Piecdesmit sestās zinātniskās konferences Bibliotēkzinātnes sekcija (1997.gada 24.septembris): tēzes
1997
Saturs: 1. Akadēmiskā bibliotēka un lasītājs: tagadne un nākotne 2. Bibliotekārā psiholoģija 3. Bibliogrāfija kā darbība un līdzekļi (Ieskats rietumvalstu bibliogrāfijas teorētiķu publikācijās) 4. Bibliotēka informācijas sabiedrībā 5. Informācijas meklējumvalodas informācijas meklēšanā 6. Informācijas meklējumvalodu uzbūve un lietošanas problēmas datorkatalogā 7 Ārzemju profesori LU 20. 30. gados 8. Kārlis Rasiņš (1886 - 1974) un apgāds "Literatūra"
Bibliotēka un sabiedrība, 3
2002
Krājumā ievietoti raksti, kuros aplūkoti jauni virzieni informācijas izplatībā un bibliotēku darbībā, kā arī informācijas sakārtošanā un apstrādē. Atsevišķos rakstos analizētas vēsturiskas parādības. Raksti izkārtoti četrās tematiskās iedaļās: "Grāmata vērtību sistēmā", "Bibliotēku vēstures pētījumi", "Publiskās bibliotēkas mūsdienu sabiedrībā" un "Informācijas avotu apstrādes problēmas".