Search results for "DDE"
showing 10 items of 1858 documents
An MDE Approach for Rapid Prototyping and Implementation of Dynamic Reconfigurable Systems
2015
This article presents a co-design methodology based on RecoMARTE, an extension to the well-known UML MARTE profile, which is used for the specification and automatic generation of Dynamic and Partially Reconfigurable Systems-on-Chip (DRSoC). This endeavor is part of a larger framework in which Model-Driven Engineering (MDE) techniques are extensively used for modeling and via model transformations, generating executable models, which are exploited by implementation tools to create reconfigurable systems. More specifically, the methodological aspects presented in this article are concerned with expediting the conception and implementation of the hardware platform and the integration of corre…
Comparison of Attention Behaviour Across User Sets through Automatic Identification of Common Areas of Interest
2020
Eye tracking is used to analyze and compare user behaviour within numerous domains, but long duration eye tracking experiments across multiple users generate millions of eye gaze samples, making th ...
Impaired Binding to Junctophilin-2 and Nanostructural Alteration in CPVT Mutation
2021
Rationale: Catecholaminergic polymorphic ventricular tachycardia (CPVT) is a rare disease, manifested by syncope or sudden death in children or young adults under stress conditions. Mutations in the Ca 2+ release channel/RyR2 (type 2 ryanodine receptor) gene account for about 60% of the identified mutations. Recently, we found and described a mutation in RyR2 N-terminal domain, RyR2 R420Q . Objective: To determine the arrhythmogenic mechanisms of this mutation. Methods and Results: Ventricular tachycardias under stress conditions were observed in both patients with catecholaminergic polymorphic ventricular tachycardia and knock-in mice. During action potential recording (by patch-clamp in …
<title>Achieving high performances at lower cost for real-time image rotation by using dynamic reconfiguration</title>
2001
FPGA components are widely used today to perform various algorithms (digital filtering) in real time. The emergence of Dynamically Reconfigurable (DR) FPGAs made it possible to reduce the number of necessary resources to carry out an image processing application (tasks chain). We present in this article an image processing application (image rotation) that exploits the FPGA's dynamic reconfiguration feature. A comparison is undertaken between the dynamic and static reconfiguration by using two criteria, cost and performance criteria. For the sake of testing the validity of our approach in terms of Algorithm and Architecture Adequacy , we realized an AT40K40 based board ARDOISE.
Keyhole limpet hemocyanin (KLH): a biomedical review
1999
In this review we present a broad survey of fundamental scientific and medically applied studies on keyhole limpet hemocyanin (KLH). Commencing with the biochemistry of KLH, information on the biosynthesis and biological role of this copper-containing respiratory protein in the marine gastropod Megathura crenulata is provided. The established methods for the purification of the two isoforms of KLH (KLH1 and KLH2) are then covered, followed by detailed accounts of the molecular mass determination, functional unit (FU) structure, carbohydrate content, immunological analysis and recent aspects of the molecular genetics of KLH. The transmission electron microscope (TEM) has contributed signific…
An Efficient Hardware implementation of MQ Decoder of JPEG2000
2014
International audience; JPEG2000 is an international standard for still images intended to overcome the shortcomings of the existing JPEG standard. Compared to JPEG image compression techniques, JPEG2000 standard has not only better not only has better compression ratios, but it also offers some exciting features. As it's hard to meet the real-time requirement of image compression systems by software, it is necessary to implement compression system by hardware. The MQ decoder of the JPEG2000 standard is an important bottleneck for real-time applications. In order to meet the real-time requirement we propose in this paper a novel architecture for a MQ decoder with high throughput which is co…
Modeling wave propagation in elastic solids via high-order accurate implicit-mesh discontinuous Galerkin methods
2022
A high-order accurate implicit-mesh discontinuous Galerkin framework for wave propagation in single-phase and bi-phase solids is presented. The framework belongs to the embedded-boundary techniques and its novelty regards the spatial discretization, which enables boundary and interface conditions to be enforced with high-order accuracy on curved embedded geometries. High-order accuracy is achieved via high-order quadrature rules for implicitly-defined domains and boundaries, whilst a cell-merging strategy addresses the presence of small cut cells. The framework is used to discretize the governing equations of elastodynamics, written using a first-order hyperbolic momentum-strain formulation…
How store design contributes to the evolution of retail brand positioning : a longitudinal case study
2014
One of the innovative ways favoured by retailers to drive change in their value proposition is to review the design of their stores. Academic contributions to the in-store experience have mostly focused on consumer perspective and identifying relevant managerial practices. The core of this research studies how repositioning a retail brand translates into the experiential design of retail spaces. To this end, the research follows the repositioning process from a managerial perspective and updates the mechanisms that underlie it. The longitudinal study of embedded cases reveals the importance of an holistic design that takes into account the desired interactions between the shopper and the st…
Induction of cholesterol biosynthesis by archazolid B in T24 bladder cancer cells.
2014
Abstract Background Resistance of cancer cells towards chemotherapeutics represents a major cause of therapy failure. The objective of our study was to evaluate cellular defense strategies in response to the novel vacuolar H+-ATPase inhibitor, archazolid B. Experimental approach: The effects of archazolid B on T24 bladder carcinoma cells were investigated by combining “omics” technologies (transcriptomics (mRNA and miRNA) and proteomics). Free cholesterol distribution was determined by filipin staining using flow cytometry and fluorescence microscopy. Flow cytometry was performed for LDLR surface expression studies. Uptake of LDL cholesterol was visualized by confocal microscopy. SREBP acti…
Isocurvature Constraints on Portal Couplings
2016
We consider portal models which are ultraweakly coupled with the Standard Model, and confront them with observational constraints on dark matter abundance and isocurvature perturbations. We assume the hidden sector to contain a real singlet scalar $s$ and a sterile neutrino $\psi$ coupled to $s$ via a pseudoscalar Yukawa term. During inflation, a primordial condensate consisting of the singlet scalar $s$ is generated, and its contribution to the isocurvature perturbations is imprinted onto the dark matter abundance. We compute the total dark matter abundance including the contributions from condensate decay and nonthermal production from the Standard Model sector. We then use the Planck lim…