Search results for "DEGRADATION"

showing 10 items of 1208 documents

Sex-related differences in D-dimer levels for venous thromboembolism screening.

2021

Background D-dimer is generally considered positive above 0.5 mg/L irrespective of sex. However, women have been shown to be more likely to have a positive D-dimer after controlling for other factors. Thus, differences may exist between males and females for using D-dimer as a marker of venous thromboembolic (VTE) disease. We hypothesized that the accuracy of D-dimer tests may be enhanced by using appropriate cutoff values that reflect sex-related differences in D-dimer levels. Methods This research is a secondary analysis of a multicenter, international, prospective, observational study of adult (18+ years) patients suspected of VTE, with low-to-intermediate pretest probability based on We…

AdultMalemedicine.medical_specialtyFibrin Fibrinogen Degradation Products03 medical and health sciences0302 clinical medicineInternal medicineD-dimermedicineHumansProspective StudiesVenous ThrombosisReceiver operating characteristicbusiness.industry030208 emergency & critical care medicineGeneral MedicineVenous Thromboembolismmedicine.diseaseConfidence intervalPulmonary embolismPre- and post-test probabilityDeep vein thrombosis (DVT)CohortEmergency MedicineFemalebusinessPulmonary EmbolismLower limbs venous ultrasonographyAcademic emergency medicine : official journal of the Society for Academic Emergency MedicineREFERENCES
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Postoperative Reduction of Fibrinolysis as a Prognostic Factor of Fatal Outcome

2001

For the resection of an esophagus carcinoma a mortality rate of 2 to 30% was described, It is still unclear whether an abdominothoracic or transhiatal intervention is superior regarding the outcome. To investigate the prognostic value of fibrinolytic markers, plasmin-α2-antiplasmin (PAP) and D-dimer (DD) values were determined daily in the early postoperative period for 11days. In addition, the course of PAP and DD concentrations was compared with the method of esophagectomy. Of the 28 patients enclosed in the study, 5 died between day 10 and day 34 owing to adult respiratory distress syndrome and septicemia. The PAP and DD concentrations increased in survivors after surgery until day 5 an…

AdultMalemedicine.medical_specialtyTime FactorsFatal outcomeEsophageal Neoplasmsmedicine.medical_treatmentReference range030204 cardiovascular system & hematologySensitivity and SpecificityGastroenterologyFibrin Fibrinogen Degradation Products03 medical and health sciences0302 clinical medicineInternal medicineFibrinolysisD-dimermedicineHumansFibrinolysinPostoperative PeriodSurvival rateAgedalpha-2-AntiplasminRespiratory distressbusiness.industryFibrinolysisMortality rateHematologyGeneral MedicineMiddle AgedPrognosisAntifibrinolytic AgentsSurgeryEsophagectomySurvival RateROC CurveEsophagectomyFemalebusinessBiomarkers030215 immunologyClinical and Applied Thrombosis/Hemostasis
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Dose-Adjusted Thrombosis Prophylaxis in Trauma Surgery According to Levels of D-Dimer

2000

In 234 trauma surgery patients, thrombosis prophylaxis with Nadroparin-Calcium low-molecular-weight heparin (LMWH) was adjusted according to levels of D-Dimer. Basic prophylaxis was 2,850 IU per day. If D-Dimer concentrations rose above 2 mg/L after the fourth postoperative (p.o.) day, LMWH was administered twice a day. Color Doppler ultrasound was performed between the fifth and seventh p.o. days. Patients were divided into a high-risk (group 1: hip, femur, or knee replacement surgery, n=102) and a moderate-risk group (group 2: other surgery of the knee, tibia, fibula, or foot, n=132). Group 1 showed significantly higher D-Dimer levels than group 2 (p0.001). Measurement of D-Dimer on days …

AdultMalemedicine.medical_specialtyTime Factorsmedicine.drug_classmedicine.medical_treatmentDeep veinAntithrombin IIIKnee replacementLow molecular weight heparinSensitivity and SpecificityFibrin Fibrinogen Degradation ProductsFractures BoneRisk FactorsAntifibrinolytic agentD-dimerHumansMedicineAgedAged 80 and overVenous Thrombosisbusiness.industryAnticoagulantNadroparinHematologyMiddle Agedmedicine.diseaseAntifibrinolytic AgentsSurgeryVenous thrombosismedicine.anatomical_structureAnesthesiaWounds and InjuriesFemalebusinessTrauma surgeryBiomarkersLeg InjuriesPeptide HydrolasesThrombosis Research
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Laboratory control of minimal heparinization during haemodialysis in patients with a risk of haemorrhage

1994

Abstract For patients undergoing dialysis with a high risk of haemorrhage there is no standardized procedure for anticoagulation during extracorporeal circulation. Minimal heparinization with a dose equivalent to half that used for chronic haemodialysis was employed in 49 patients (125 haemodialyses) performed after operative interventions (83.3%), after haemorrhagic events (5.2%) and after invasive investigations (11.5%). Using a biocompatible membrane and a low molecular weight heparin (bolus dose 500-1300 U; continuous infusion 100-400 U) it was possible to complete haemodialysis in 74 cases (Group 0) without clots appearing in the venous bubble trap of the tubing system. In 30 cases (Gr…

AdultMalemedicine.medical_specialtymedicine.drug_classmedicine.medical_treatmentAntithrombin IIILow molecular weight heparinHemorrhageFibrin Fibrinogen Degradation ProductsClinical ProtocolsRenal DialysisRisk FactorsmedicineHumansIn patientRisk factorDialysisAgedMonitoring PhysiologicDose-Response Relationship Drugbusiness.industryAnticoagulantExtracorporeal circulationHematologyGeneral MedicineHeparinHeparin Low-Molecular-WeightMiddle AgedAntifibrinolytic AgentsSurgeryFemaleHemodialysisbusinessPeptide Hydrolasesmedicine.drugBlood Coagulation & Fibrinolysis
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Evaluation of the Stratus® CS Acute Care™ D-dimer assay (DDMR) using the Stratus® CS STAT Fluorometric Analyzer: A prospective multisite study for ex…

2012

Abstract Background D-dimer testing is an integral part of the diagnostic algorithm in excluding patients with venous thromboembolism. In this study, we prospectively evaluated the Stratus DDMR D-dimer test in patients suspected of pulmonary embolism (PE) and deep vein thrombosis (DVT). Methods Patients suspected of venous thromboembolism were prospectively enrolled at four different clinical sites, with sodium citrate and lithium heparin plasma was tested using the DDMR D-dimer test on the Stratus CS analyzer. Results 1,012 patients were enrolled for analysis, with 85/603 (14.1%) patients with PE and 80/443 (18.1%) with DVT, and four of the patients (0.4%) with PE and DVT. For the samples …

Adultmedicine.medical_specialtyDeep veinGastroenterologyD-dimer assayFibrin Fibrinogen Degradation ProductsYoung AdultInternal medicineAcute caremedicineHumansFluorometryProspective Studiescardiovascular diseasesProspective cohort studyAgedAged 80 and overImmunoassayVenous Thrombosisbusiness.industryHematologyHeparinMiddle Agedmedicine.diseaseThrombosisPulmonary embolismSurgerymedicine.anatomical_structurePulmonary EmbolismbusinessVenous thromboembolismmedicine.drugThrombosis Research
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Reactivation of aerobic granular sludge for the treatment of industrial shipboard slop wastewater: Effects of long-term storage on granules structure…

2021

Abstract This work reports on reactivation of aerobic granular sludge (AGS) for the treatment of industrial recalcitrant wastewater (slop wastewater) characterized by high salinity and hydrocarbons. AGS were reactivated in two reactors, R1 and R2, to treat industrial slop wastewater after a long-term storage for 12-months at 4 °C. In R1, salt-adapted mature aerobic granules were previously subjected to a step-wise increase of hydrocarbons, whereas in R2 aerobic granules were previously cultivated in presence of salinity and hydrocarbons. After a short-term reactivation period, the slop dosage caused a simultaneous decrease of granules dimensions and proteins/polysaccharides (PN/PS) ratio do…

Aerobic granular sludge reactivationNGS 16S rDNA02 engineering and technology010501 environmental sciences01 natural sciencesIndustrial wastewater treatmentGranulationIndustrial wastewater020401 chemical engineering0204 chemical engineeringSafety Risk Reliability and QualityTPH hydrocarbonWaste Management and Disposal0105 earth and related environmental sciencesbiologyChemistryProcess Chemistry and TechnologyBiofilmBiodegradationPulp and paper industrybiology.organism_classificationSalinityWastewaterMicrobial population biologyEPSBacteriaBiotechnology
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Beyond Biodegradability of Poly(lactic acid): Physical and Chemical Stability in Humid Environments

2017

International audience; Poly(lactic acid) (PLA) is the most traded biodegradable and biobased material. It is largely used as ecofriendly substitute of conventional plastics. Nevertheless, one of the main limiting factors is its water sensitivity. PLA reacts with water and is hydrolyzed during time, which determines its performance. Limited information related to the hydrolysis mechanism driven by water in vapor state is available in scientific literature. Literature is mainly focused on the effects of water in liquid state. This lack of information is of significant importance, since PLA interacts with water in both phases. This work was aimed to give a full depiction of the chemical and p…

AgingHydrolytic degradationPhosphate-buffered solutionGeneral Chemical EngineeringAmorphous fractions02 engineering and technologyPolylactide010402 general chemistry01 natural sciencesBioplasticHydrolysischemistry.chemical_compoundGlass-transition[SDV.IDA]Life Sciences [q-bio]/Food engineeringEnvironmental ChemistryOrganic chemistryRelative humidityRelative-humidityState of waterPoly(l-lactic acid)Renewable Energy Sustainability and the EnvironmentChemistryHydrolysisAmorphous phase[ SDV.IDA ] Life Sciences [q-bio]/Food engineeringtechnology industry and agricultureGeneral ChemistryBiodegradationequipment and supplies021001 nanoscience & nanotechnology0104 chemical sciencesLactic acidBioplasticLactide copolymersPLADegradation (geology)Chemical stabilityIn-vitro degradation0210 nano-technologyGlass transitionACS Sustainable Chemistry & Engineering
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Updated measurements in vineyards improves accuracy of soil erosion rates

2018

All rights reserved. Vineyards have proven to be one of the most degraded agricultural ecosystems due to very high erosion rates, which are typically measured at fine temporal and spatial scales. Long-term soil erosion measures are rare, but this information may be indispensable for a proper understanding of the vineyard soil system, landscape evolution, and crop production. The stock unearthing method (SUM) is a common topographical measurement technique developed to assess long-term erosion rates. The reliance of the SUM has been questioned and should be replaced by an improved measurement technique. In this paper, we demonstrate the added value (improved accurate, low cost, and faster th…

Agricultural ecosystemsSoil science04 agricultural and veterinary sciences010501 environmental sciencesBodemfysica en LandbeheerPE&RC01 natural sciencesVineyardTillageSoil Physics and Land ManagementSoil lossAgronomy040103 agronomy & agricultureErosionLand degradation0401 agriculture forestry and fisheriesEnvironmental scienceLife ScienceAgronomy and Crop ScienceStock (geology)Soil movement0105 earth and related environmental sciences
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Agricultural management affects the response of soil bacterial community structure and respiration to water-stress

2013

International audience; Soil microorganisms are responsible for organic matter decomposition processes that regulate soil carbon storage and mineralisation to CO2. Climate change is predicted to increase the frequency of drought events, with uncertain consequences for soil microbial communities. In this study we tested the hypothesis that agricultural management used to enhance soil carbon stocks would increase the stability of microbial community structure and activity in response to water-stress. Soil was sampled from a long-term field trial with three soil carbon management systems and was used in a laboratory study of the effect of a dry wet cycle on organic C mineralisation and microbi…

Agricultural land use010504 meteorology & atmospheric sciencesSoil biodiversity[SDV]Life Sciences [q-bio]Soil biologySoil Science01 natural sciencesMicrobiologyDrying-rewettingFUNCTIONAL STABILITYSoil retrogression and degradation[SDV.BV]Life Sciences [q-bio]/Vegetal BiologyOrganic matterGlobal changeNITROGEN MINERALIZATION0105 earth and related environmental sciences2. Zero hungerchemistry.chemical_classificationC mineralisationCLIMATE-CHANGEMICROBIAL COMMUNITYEcologySoil organic matterLAND-USE CHANGE04 agricultural and veterinary sciencesSoil carbonRESILIENCE15. Life on landDRYING-REWETTING FREQUENCYORGANIC-MATTERAgronomychemistryMicrobial population biology13. Climate action[SDE]Environmental Sciences040103 agronomy & agricultureBacterial community structure0401 agriculture forestry and fisheriesEnvironmental scienceCATABOLIC DIVERSITYCARBON STOCKSMicrocosmStabilitySoil Biology and Biochemistry
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Bio‐based Materials

2021

Agricultural wasteWaste managementEnvironmental scienceBio basedBiodegradationPackaging Materials and Processing for Food, Pharmaceuticals and Cosmetics
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