Search results for "DEP"

showing 10 items of 10555 documents

Abemaciclib: safety and effectiveness of a unique cyclin-dependent kinase inhibitor

2020

Introduction: The discovery and the clinical availability of novel cyclin-dependent kinases 4 and 6 inhibitors have profoundly changed the therapeutic scenario of metastatic hormone receptor-positive breast carcinoma. Among these inhibitors, abemaciclib can induce potent and sustained cell cycle arrest and immune system stimulation. Areas covered: This review summarizes the safety profile and clinical efficacy data on abemaciclib alone or in combination with aromatase inhibitors or fulvestrant in metastatic hormone receptor-positive breast carcinoma. The management of patients treated with abemaciclib is the object of this paper. Expert opinion: As shown in phase 2 and 3 clinical trials on …

safetyAminopyridinesBreast Neoplasms030204 cardiovascular system & hematology03 medical and health scienceschemistry.chemical_compoundabemaciclib breast cancer metastases hormonal receptors safetybreast cancer0302 clinical medicineBreast cancerCyclin-dependent kinaseAntineoplastic Combined Chemotherapy ProtocolsmedicineHumansPharmacology (medical)metastasesskin and connective tissue diseasesFulvestrantProtein Kinase InhibitorsAbemaciclibbiologyAromatase Inhibitorsbusiness.industryKinasehormonal receptorsCyclin-Dependent Kinase 4Cell Cycle CheckpointsCyclin-Dependent Kinase 6General Medicinemedicine.diseaseAbemaciclibchemistry030220 oncology & carcinogenesisQuality of LifeCancer researchbiology.proteinBenzimidazolesFemalesense organsbusinessHormone
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Eina interactiva per a l'anàlisi de fraus editorials en salut

2019

Revistes depredadores; Fraus editorials; Investigació; Publicació Predatory magazines; Editorial frauds; Investigation; Publication Revistas depredadoras; Fraudes editoriales; Investigación; Publicación INTRODUCCIÓ Es presenta una eina destinada als investigadors, elaborada a la Biblioteca de Ciències de la Salut de la UV. L’objectiu és comprovar la credibilitat de revistes potencialment fraudulentes, mitjançant l’anàlisi de la seua presència en bases de dades, recursos d’avaluacio de revistes científiques i el seu grau d’acompliment dels criteris de les associacions d’editors de publicacions mèdiques: https://airtable.com/shruAWiTvt9ubJnCn/tblRP5wUJfU83lbv5?blocks=hide MÈTODE S'ha partit d…

salutSalut - Revistes - AvaluacióUNESCO::CIENCIAS MÉDICAS:Health Sciences Technology and Innovation Management::Scientific Communication and Diffusion::Support and Finance Policies on Scientific Publishing::Systems for Evaluation of Publications [SCIENCE AND HEALTH]revistes depredadoresEdició científica:Publication Formats::Periodical [PUBLICATION CHARACTERISTICS]:gestión de ciencia tecnología e innovación en salud::comunicación y difusión científica::políticas de apoyo y financiación de las publicaciones científicas::sistemas para la evaluación de las publicaciones [CIENCIA Y SALUD]:formatos de publicación::publicación periódica [CARACTERÍSTICAS DE PUBLICACIONES]fraus editorials
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Sarūkošu pilsētu plānošana: Daugavpils piemērs

2020

Maģistra darba tēma ir Sarūkošu pilsētu plānošana: Daugavpils piemērs. Kopš 1992.gada iedzīvotāju skaits Daugavpilī ir samazinājies par 35,3% jeb 45015 iedzīvotājiem. Tādās Latvijas pilsētās kā Rīga, Liepāja, kas ir atzīmētas Sarūkošu pilsētu atlantā, ir veikti pētījumi par sarukšanas cēloņiem, attīstības prognozēm, sarukšanas ietekmi un sarukšanas noturības avotiem, bet Latvijas Republikas otrajā lielākajā pilsētā, kas ir nozīmīgs sociāli ekonomiskās attīstības centrs pie Latvijas austrumu robežas šādi pētījumi nav veikti. Līdz ar to darba mērķis ir izstrādāt priekšlikumus Daugavpils pilsētai, balstoties uz Eiropas un pasaules labās prakses piemēriem un sociālekonomiskajiem procesiem. Darb…

sarukšanaArhitektūradepopulācijapriekšlikumiDaugavpils
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Svenskundervisning för mentalt handikappade vid Södra Österbottens socialpsykiatriska förenings dagcenter

2003

schitzofreniöversättningsuppgifterskitsofreniadepressiodepressionindividuella skillnadergrammatiktestyksilöllisyys
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CAN PRS FOR SCHIZOPHRENIA, BIPOLAR DISORDER AND MAJOR DEPRESSION DISTINGUISH AFFECTIVE PSYCHOSIS DIAGNOSTIC CATEGORIES? THE EU-GEI STUDY

2019

schizophreniaPRSmajor depressionbipolar
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ENVIRONMENTAL RISK FACTORS DIFFERENCES AMONG DIAGNOSTIC CATEGORIES IN EU-GEI STUDY

2019

schizophreniamajor depressionenvironmentbipolar
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Population structure of the sea urchins Paracentrotus lividus and Arbacia lixula across a depth gradient

2006

Sea urchins are considered to have a paramount role in structuring rocky shallow communities. Under certain conditions, grazing by sea-urchins has been reported to produce a shift from macroalgae-dominated communities to barren habitat dominated by encrusting algae. However, this process is not recorded at all depths. The effect of depth on the structure of the sea-urchin populations may be thus a key feature to understand the origin and maintenance of the barren habitat within certain depths. In the present study, the structure of Paracentrotus lividus (Lam.) and Arbacia lixula (L.) populations are analyzed across a depth gradient in the Ustica Island MPA (NW Mediterranean), where the barr…

sea urchin depth Paracentrotus Arbacia
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Depression and Sequential Decision-Making Revisited

2019

Background: The effect of depression on decision-making is an important but still an unsettled issue. Although most studies have reported that clinically depressed participants show worse performance, there are also studies that have shown no or even positive effects. Specifically, von Helversen et al. (2011) were able to document a positive effect of depression on task performance in a sequential decision-making task called the secretary problem (SP). Here, we (1) aimed to replicate this study in an extended version using more trials and (2) modified it by including an additional condition in which negative feedback was given. Method: Eighty-two participants took part. They were split into…

secretary problemlcsh:Psychologymajor depressive disordersequential decision150 Psychologielcsh:BF1-990Psychologydecision-making150 Psychologypunishment sensitivityOriginal ResearchFrontiers in Psychology
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Nuevas faunas de micromamíferos del Terciario continental de la Depresión Intermedia (provincia de Cuenca, España centro-oriental)

1986

In this paper the fossil content of nine new micromammal bearing localities and that of 15 levels in a borehole from the Loranca Basin (eastern Tague Basin, Prov. of Cuenca) is described. The age ranges from early Arvernian (Late Oligocene) to Turolian (Late Miocene). 47 rodent and lagomorph taxons have been found which are arranged in 8 biostratigraphic units. The Loranca-2 borehole contains 15 fossiliferous levels covering the Upper Oligocene/Lower Miocene. These additional data complete the faunal sequence published by Díaz & López(1919). The stratigraphic framework of the basin needs a revision because of the new faunal data.<br><br>Se presenta una serie de 9 nuevos yaci…

secuencia estratigráfica.Depresión IntermediaBiozoneStructural basinLate Miocenesondeo MicromamíferosSequence (geology)PaleontologyLoranca basinmicromamalsdepresión intermediamicromamíferosQE1-996.5sondeocontinentalborcholelcsh:QE1-996.5biostratigraphic sequence.Terciario continentalGeologyterciario continentallcsh:GeologyMicromamíferosTertiaryGeologyEstudios Geológicos
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Relación entre inteligencia emocional, recursos y problemas psicológicos, en la infancia y adolescencia

2016

Desde que Salovey y Mayer (1990) acuñaran el término Inteligencia Emocional, han sido desarrollados diferentes modelos. Los modelos con más apoyo científico son: el modelo de habilidad de Mayer y Salovey (1997; Brackett y Salovey, 2006) y el modelo de Bar-On de Inteligencia Emocional-Social (IES; Bar-On, 1997a,2000, 2006). Bar-On (1997a, 2000, 2006) consideró la Inteligencia Emocional como un conjunto de rasgos estables de personalidad, competencias socio-emocionales, aspectos motivacionales y diversas habilidades cognitivas, que aluden a contenidos de tipo emocional y social, que influyen en la conducta inteligente y determinan nuestra eficacia para comprender y relacionarnos con otras per…

segunda infanciaadolescenciainteligencia emocionaldepresión:PSICOLOGÍA [UNESCO]ansiedadUNESCO::PSICOLOGÍAcompetenciasfortalezasquejas somáticas
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