Search results for "DEPARTMENTS"

showing 10 items of 13 documents

Managing adult patients with infectious diseases in emergency departments: international ID-IRI study.

2021

We aimed to explore factors for optimizing antimicrobial treatment in emergency departments. A single-day point prevalence survey was conducted on January 18, 2020, in 53 referral/tertiary hospitals in 22 countries. 1957 (17%) of 11557 patients presenting to EDs had infections. The mean qSOFA score was 0.37 +/- 0.74. Sepsis (qSOFA >= 2) was recorded in 218 (11.1%) patients. The mean qSOFA score was significantly higher in low-middle (1.48 +/- 0.963) compared to upper-middle (0.17 +/- 0.482) and high-income (0.36 +/- 0.714) countries ( P < 0.001). Eight (3.7%) patients with sepsis were treated as outpatients. The most common diagnoses were upper-respiratory (n = 877, 43.3%), lower-respirator…

0301 basic medicinePoint prevalence surveymedicine.medical_specialtyUrologic NeoplasmsReferralinternational ID-IRI study- JOURNAL OF CHEMOTHERAPY 2021 [Erdem H. Hargreaves S. ANKARALI H. ÇAŞKURLU H. Ceviker S. A. Bahar-Kacmaz A. Meric-Koc M. ALTINDİŞ M. Yildiz-Kirazaldi Y. Kizilates F. et al. -Managing adult patients with infectious diseases in emergency departments]medicine.drug_classOrgan Dysfunction Scores030106 microbiologyAntibioticsPractice Patternsemergency ; antibiotic ; elderly ; infection ; sepsis ; treatmentGlobal HealthelderlyCommunicable Diseasestreatment.SepsisHospital03 medical and health sciences0302 clinical medicineantibioticSepsismedicineHumansPharmacology (medical)Practice Patterns Physicians'Developing CountriesRespiratory Tract InfectionsPharmacologyEmergency ServicePhysicians'Adult patientstreatmentbusiness.industryPatient AcuityAntimicrobialmedicine.diseasehumanitiesinfectionDrug UtilizationAnti-Bacterial AgentsInfectious DiseasesOncology030220 oncology & carcinogenesisEmergency medicineEmergencysepsibusinessEmergency Service HospitalJournal of chemotherapy (Florence, Italy)
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Construction of a genetically modified wine yeast strain expressing the Aspergillus aculeatus rhaA gene, encoding an -L-Rhamnosidase of enological in…

2003

Monoterpenes such as geraniol, linalool, and -terpineol present in grapes determine the varietal flavor properties of young quality wines made from Muscat varieties (for reviews, see references 19 and 21). Geraniol and linalool are considered to be the most important of the monoterpene alcohols, as they are present in greater concentrations and have lower flavor thresholds than other major wine monoterpenes. In particular, linalool is thought to be responsible for the grapelike aroma of wines produced from the Muscat variety. A large proportion of

AFSG Stafafdelingen (WUATV)Glycoside HydrolasespurificationAcyclic MonoterpenesMonoterpenepurifying glycosidasesWineSaccharomyces cerevisiaeMicrobiologyApplied Microbiology and Biotechnologychemistry.chemical_compoundLinalooll-rhamnopyranosidaseMicrobiologieVitisFood scienceFlavorVLAGAlpha-L-rhamnosidasel-arabinofuranosidaseWineEcologybiologybeta-GlucosidaseAspergillus aculeatusbeta-d-glucopyranosidasefood and beveragesbiology.organism_classificationAFSG Staff Departments (WUATV)Yeast in winemakingAspergillusBiochemistrychemistryaromaFermentationMonoterpenesFood Microbiologymicrovinification processessaccharomyces-cerevisiaeGenetic EngineeringnigerGeraniolFood ScienceBiotechnologygrape juice
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Measuring well-being in Colombian departments. The role of geography and demography

2021

This paper provides a composite indicator of well-being for the 33 Colombian departments in the year 2016. The indicator is built by adapting the well-known OECD Better Life Index to the regional level, and includes the dimensions of income, health, education, safety, housing, environment, labour market, and civic engagement and governance. As to the methodology, Data Envelopment Analysis and Multi-Criteria Decision-Making techniques are employed, an approach which enables a comparison of well-being across departments and the construction of rankings. The results yield several take-away messages. First, there are substantial disparities in well-being across Colombian departments. Second, de…

Economics and EconometricsIndex (economics)Strategy and ManagementYield (finance)Geography Planning and DevelopmentPopulation0211 other engineering and technologiesdepartments02 engineering and technologyColombiaManagement Science and Operations Researchwell-being0502 economics and businessData envelopment analysisCivic engagement050207 economicseducationeducation.field_of_study021103 operations researchCorporate governance05 social sciencesComposite indicatorGeographyWell-beingDemographic economicsStatistics Probability and Uncertaintycomposite indicatorsSocio-Economic Planning Sciences
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The Italian legal clinics movement. Data and prospects

2015

It is not more than 5 years since legal clinics were founded in Italian Universities: a very recent history indeed and similar to that of other Western European countries. I will try to explain this through some data collected by an inquiry that I ran in order to have a more detailed map of this phenomena and to conjecture its future evolution. In the following paragraphs I will present the data inquiry and I will try to explain the process of establishing the Italian movement for legal education, its options and challenges. It is worth pointing out why I use the term “movement”. What is going on in Italy, and I think elsewhere, is not simply the proliferation of single clinics, but the eme…

Legal clinical educationItalian law departmentsSocial justice
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Risk factors for hospital readmission of elderly patients

2012

Background: The aim of this study was to identify which factors were associated with a risk of hospital readmission within 3 months after discharge of a sample of elderly patients admitted to internal medicine and geriatric wards. Methods: Of the 1178 patients aged 65 years or more and discharged from one of the 66 wards of the 'Registry Politerapie SIMI (REPOSI)' during 2010, 766 were followed up by phone interview 3 months after discharge and were included in this analysis. Univariate and multivariate logistic regression models were used to evaluate the association of several variables with rehospitalization within 3 months from discharge. Results: Nineteen percent of patients were readmi…

MaleSettore MED/09 - Medicina InternaTime FactorsRisk factors; internal medicine; Geriatric patient; hospital admissionLogistic regressionElderly; Hospital readmission; Internal medicine and geriatric wards; Risk factorsElderlyInternal medicine and geriatric wards80 and overElderly; Hospital readmission; Internal medicine and geriatric wards; Risk factors; Aged; Aged 80 and over; Female; Geriatrics; Hospital Departments; Humans; Internal Medicine; Male; Patient Readmission; Risk Factors; Time Factors; Internal MedicineMedical diagnosisAged Aged; 80 and over Female Geriatrics Hospital Departments Humans Internal Medicine Male Patient Readmission; statistics /&/ numerical data Risk Factors Time FactorsAged 80 and overGeriatricsUnivariate analysisvascular diseaseHospital readmissionSettore MED/45 - Scienze Infermieristiche Generali Cliniche E PediatricheAgeing; readmissionstatistics /&/ numerical dataHospital DepartmentFemaleliver diseaseHumanmedicine.medical_specialtyTime FactorHospital DepartmentsMEDLINEHospital readmission Internal medicine and geriatric wards Risk factors Elderlyelderly patientsPatient ReadmissionNOInternal MedicinemedicineHumansRegistry Politerapie SIMI (REPOSI)Adverse effectAgedreadmissionbusiness.industryRisk FactorUnivariatemedicine.diseaseComorbidityHospital readmission; elderly patients; Registry Politerapie SIMI (REPOSI); vascular disease; liver diseaseHospital readmission; Internal medicine and geriatric wards; Risk factors; Elderlyelderly; hospital readmission; risk factors; internal medicine and geriatric wardsInternal medicine and geriatric wardAgeingGeriatric patienthospital admissionRisk factorsGeriatricsEmergency medicinebusinessGeriatricEuropean Journal of Internal Medicine
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Drug Prescription and Delirium in Older Inpatients: Results From the Nationwide Multicenter Italian Delirium Day 2015-2016

2019

Objective This study aimed to evaluate the association between polypharmacy and delirium, the association of specific drug categories with delirium, and the differences in drug-delirium association between medical and surgical units and according to dementia diagnosis. Methods Data were collected during 2 waves of Delirium Day, a multicenter delirium prevalence study including patients (aged 65 years or older) admitted to acute and long-term care wards in Italy (2015-2016); in this study, only patients enrolled in acute hospital wards were selected (n = 4,133). Delirium was assessed according to score on the 4 "A's" Test. Prescriptions were classified by main drug categories; polypharmacy w…

Malediagnosismedications0302 clinical medicinepreventionAged 80 and over; Delirium; Drug Prescriptions; Female; Hospital Departments; Humans; Male; Prevalence; Polypharmacy; Prescription Drugs80 and overPrevalenceMedicineLS4_4030212 general & internal medicineAcute hospitalmedia_commonAged 80 and overConfoundingelderly patients hip fracture hospitalized patients prediction rule risk factor dementia events medications prevention diagnosisrisk-factorrisk factorhip fracturePsychiatry and Mental HealthFemalemedicine.symptomeventsDrugmedicine.medical_specialtyPrescription Drugshospitalized-patientsmedia_common.quotation_subjectMEDLINEHospital DepartmentsSocio-culturaleelderly-patientselderly patientsbehavioral disciplines and activitiesDrug Prescriptions03 medical and health sciencesInternal medicinemental disordersDementiaHumansMedical prescriptionprediction ruleAgedPolypharmacybusiness.industryhospitalized patientsDeliriummedicine.diseasenervous system diseasesPolypharmacyDeliriumelderly-patients; hip fracture; hospitalized-patients; prediction rule; risk-factor; dementia; events; medications; prevention; diagnosisbusiness030217 neurology & neurosurgerydementia
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GDS score as screening tool to assess the risk of impact of chronic conditions and depression on quality of life in hospitalized elderly patients in …

2021

Aging of population is characterized by multiple chronic conditions in the same individual. Health-related quality of life (HR-QOL) reflects the multidimensional impact of chronic disease on population and it is increasingly analysed as outcomes. The aim of this study was the evaluation of the predictors of quality of life among elderly patients hospitalized in internal medicine ward, investigating the effect of comorbidities on health-related quality of life. Data collected in this cross-sectional study were analysed. Socio-demographic, clinical characteristics, disease distribution and quality of life by the 12-Item Short Form Health Survey (SF-12) were evaluated. Of 240 inpatients, subje…

Malemedicine.medical_specialtyfrail eldersMultivariate analysisCross-sectional studyFrail ElderlyPopulationHospital DepartmentsObservational StudyPatient Health Questionnairebehavioral disciplines and activities500003 medical and health sciences0302 clinical medicineQuality of lifeNeoplasmsInternal medicineDiabetes MellitusInternal MedicineHumansMedicine030212 general & internal medicineeducationDepression (differential diagnoses)Agededucation.field_of_studyDepressionbusiness.industryLiver DiseasesSocial Supportmultiple chronic conditionsGeneral MedicineMental healthhumanitiesHospitalizationPatient Health Questionnairedepression frail elders multiple chronic conditions quality of life Aged Cross-Sectional Studies Depression Diabetes Mellitus Female Frail Elderly Hospital Departments Humans Internal Medicine Liver Diseases MaleMultiple Chronic Conditions Neoplasms Social Support Hospitalization Patient Health Questionnaire Quality of LifeCross-Sectional Studiesquality of life030220 oncology & carcinogenesisFemaleGeriatric Depression ScalebusinessResearch Article
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Structure of Rhodococcus erythropolis limonene-1,2-epoxide hydrolase reveals a novel active site

2003

Epoxide hydrolases are essential for the processing of epoxide-containing compounds in detoxification or metabolism. The classic epoxide hydrolases have an alpha/beta hydrolase fold and act via a two-step reaction mechanism including an enzyme-substrate intermediate. We report here the structure of the limonene-1,2-epoxide hydrolase from Rhodococcus erythropolis, solved using single-wavelength anomalous dispersion from a selenomethionine-substituted protein and refined at 1.2 A resolution. This enzyme represents a completely different structure and a novel one-step mechanism. The fold features a highly curved six-stranded mixed beta-sheet, with four alpha-helices packed onto it to create a …

Models MolecularAFSG Stafafdelingen (WUATV)10050 Institute of Pharmacology and Toxicologydrug protein bindingEnantioselectivityEpoxide hydrolaseCrystallography X-Rayuncultured actinomyceteCatalytic Domain2400 General Immunology and Microbiologyalpha helixRhodococcuscholesterol epoxide hydrolasenaphthalene 12-dioxygenasedcl14limonene 12 epoxide hydrolaseEpoxide hydrolaseBacteria (microorganisms)delta(5)-3-ketosteroid isomeraseEpoxide HydrolasesLimonene-12-epoxide hydrolaseGeneral Neurosciencearticle2800 General NeuroscienceActinobacteria (class)Articlesagrobacterium-radiobacterEnzyme structureRecombinant Proteinsunclassified drugenzyme structurereaction analysisBiochemistrypriority journalenzyme active siteMechanism2-dioxygenaseDimerizationBiotechnologychemical reactioncrystal structureaspergillus-nigermacromolecular structuresStereochemistrybeta sheetvalpromideMolecular Sequence Data610 Medicine & healthGenetics and Molecular BiologyBiologyGeneral Biochemistry Genetics and Molecular BiologyBacterial Proteinssite directed mutagenesis1300 General Biochemistry Genetics and Molecular BiologyHydrolase1312 Molecular BiologyAmino Acid SequencedetoxificationRhodococcus erythropolisBiologyMonoterpene degradationMolecular Biologyprotein data-bankenzyme substrate complexEnzyme substrate complexnonhumancatalysisSequence Homology Amino AcidGeneral Immunology and Microbiologybacterial enzymeActive sitecrystal-structureAFSG Staff Departments (WUATV)enzyme metabolismProtein SubunitsenzymeEpoxide HydrolasesGeneral Biochemistrybiology.proteinMutagenesis Site-Directed570 Life sciences; biologyselenomethioninenaphthalene 1Alpha helix
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Strict blood-pressure control and progression of renal failure in children

2009

PubMedID: 19846849 BACKGROUND: Although inhibition of the renin-angiotensin system delays the progression of renal failure in adults with chronic kidney disease, the blood-pressure target for optimal renal protection is controversial. We assessed the long-term renoprotective effect of intensified blood-pressure control among children who were receiving a fixed high dose of an angiotensin-converting- enzyme (ACE) inhibitor. METHODS: After a 6-month run-in period, 385 children, 3 to 18 years of age, with chronic kidney disease (glomerular filtration rate of 15 to 80 ml per minute per 1.73 m2 of body-surface area) received ramipril at a dose of 6 mg per square meter of bodysurface area per day…

RamiprilMaleMean arterial pressuremedicine.medical_specialtyAdolescentUrologyRenal functionAngiotensin-Converting Enzyme InhibitorsBlood PressureKaplan-Meier EstimateRamiprilmedicineClinical endpointHumansRenal Insufficiency ChronicChildDEPARTMENTSAntihypertensive AgentsProteinuriabusiness.industryHazard ratioGeneral MedicineBlood Pressure Monitoring Ambulatorymedicine.diseaseSurgeryProteinuriaBlood pressureChild PreschoolCreatinineHypertensionDisease ProgressionKidney Failure ChronicDrug Therapy CombinationFemalemedicine.symptombusinessKidney diseasemedicine.drugGlomerular Filtration Rate
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Análisis de las dinámicas de producción de conocimiento científico bajo el sistema de evaluación de la calidad de la Educación Superior y la Ciencia

2021

Tesis doctoral.-- Universidad de Valencia.

carrera académicaUniversitySociology of scienceDepartmentsconocimiento científicoSciencepolíticas de evaluación:SOCIOLOGÍA [UNESCO]DisciplinesEvaluation studiesevaluaciónresearch evaluationpolítica científicaKnowledge productionUNESCO::SOCIOLOGÍAScience policyproducción de conocimiento científicosociologia de la cienciasistemas de evaluaciónuniversidad
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