Search results for "DERIVATIVES"

showing 10 items of 432 documents

ChemInform Abstract: Indirect Regioselective Heteroarylation of Indoles Through a Friedel-Crafts Reaction with (E)-1,4-Diaryl-2-buten-1,4-diones.

2010

Abstract A two-step synthesis of 3-heteroaryl indoles has been developed. The first step of the sequence involves a Friedel–Crafts alkylation of indoles with 1,4-diaryl-2-buten-1,4-diones to give the corresponding indoles bearing a 1,4-dicarbonyl moiety. The reaction is catalyzed by InCl 3 and takes place with good yields. Cyclization of the diones under different Paal–Knorr conditions allows to prepare indoles substituted at the C3 position with 3-furanyl, 3-pyrrolyl- and 3-thienyl moieties.

ChemistryMoietyRegioselectivityGeneral MedicineAlkylationThiophene derivativesMedicinal chemistryFriedel–Crafts reactionPyrrole derivativesCatalysisChemInform
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ChemInform Abstract: THE PREPARATION OF DIHYDROXYDIPHENYLMETHANE DERIVATIVES CONTAINING NITRO GROUPS PART 1, SYMMETRICALLY SUBSTITUTED COMPOUNDS

1974

(1974). THE PREPARATION OF DIHYDROXYDIPHENYLMETHANE DERIVATIVES CONTAINING NITRO GROUPS. I. SYMMETRICALLY SUBSTITUTED COMPOUNDS. Organic Preparations and Procedures International: Vol. 6, No. 3, pp. 123-130.

ChemistryNitroGeneral MedicineMedicinal chemistryDiphenylmethane derivativesChemischer Informationsdienst
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Synthetic Strategies Towards O6-Substituted Guanine Derivatives and their Application in Medicine

2005

ChemistryOrganic ChemistryGuanine derivativesOrganic chemistryPurine derivativeGeneral MedicineBiochemistryCombinatorial chemistryCurrent Organic Synthesis
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ChemInform Abstract: A Convenient and General Synthesis of Alkanediyl Diphenols.

2010

ChemistryOrganic chemistryGeneral MedicineCondensation reactionDiphenylmethane derivativesChemInform
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ChemInform Abstract: Pyrrolidino Enaminones Structurally Related to Gyrase Inhibitors: Synthesis, Cyclization and Pharmacological Activity.

2010

ChemistryStereochemistryBiological activityGeneral MedicineDNA gyraseCombinatorial chemistryPyrrole derivativesChemInform
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ChemInform Abstract: H2-Antihistaminics. Part 35. Synthesis and H2-Antagonistic Activity of Imidazolylmethylthioalkyl-Substituted 1,2,4-Triazoles.

1987

ChemistryTriazole derivativesGeneral MedicineCombinatorial chemistryChemInform
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ChemInform Abstract: Synthesis of Amino-1,2,4-triazoles by Reductive ANRORC Rearrangements of 1,2,4-Oxadiazoles.

2011

The hydrazinolysis of the oxadiazoles under optimized conditions allows a general synthesis of functionalized aminotriazole products which are of interest due to the biological activity of the heterocyclic system.

ChemistryTriazole derivativesOrganic chemistryBiological activityGeneral MedicineChemInform
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ChemInform Abstract: A Facile Route to New Potential Helicating Ligands.

2010

Abstract The synthesis of new bitriazolopyridines, 6,6′-disubstituted-2,2′-bipyridines and 2-pyridyl-6-(2-pyridylcarbonyl)-2-pyridylmethanone potential helicating ligands from 3-(2-aryl)-[1,2,3]triazolo[1,5-a]pyridines is described.

ChemistryTriazole derivativesOrganic chemistryGeneral MedicineChemInform
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ChemInform Abstract: New Reactions of Vinylindoles as Heterocyclic Dienes with 4-Phenyl-1,2,4-triazoline-3,5-dione: Non-Concerted versus Concerted Pr…

2010

ChemistryTriazole derivativesOrganic chemistryGeneral MedicineChemInform
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Synthesis of 3-triazenopyrroles

1993

Abstract The 3-triazenopyrroles, a new class of pyrrole derivatives, were synthesized in quantitative yield by coupling 3-diazopyrroles with secondary amines.

ChemistryYield (chemistry)Organic ChemistryOrganic chemistryCombinatorial chemistryPyrrole derivatives
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