Search results for "DESIGN"

showing 10 items of 5885 documents

Optimization design process of a morphing winglet

2018

Aeronautic and aerospace engineering is recently moving in the direction of developing morphing wing devices, with the aim of making adaptable the aerodynamic shapes to different operational conditions. Those devices may be classified according to two different conceptual architectures: kinematic or compliant systems. Both of them embed within their body all the active components (actuators and sensors), necessary to their operations. In the first case, the geometry variation is achieved through an augmented classical mechanism, while in the second case the form modification is due to a special arrangement of the inner structure creating a distributed elastic hinges arrangement. Whatever is…

Adaptive winglet topology optimization morphing devices load alleviation and controlWingProcess (engineering)Computer scienceTopology optimizationControl engineering02 engineering and technologyAerodynamicsKinematics021001 nanoscience & nanotechnologyAeroelasticity01 natural sciences010309 opticsMorphingRobustness (computer science)Adaptive system0103 physical sciencesSystems architectureDesign processWingtip deviceSettore ING-IND/04 - Costruzioni E Strutture Aerospaziali0210 nano-technologyEngineering design processActuatorBioinspiration, Biomimetics, and Bioreplication VIII
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Intraprocedural bowel cleansing with the JetPrep cleansing system improves adenoma detection.

2014

AIM: To investigate the impact of JetPrep cleansing on adenoma detection rates. METHODS: In this prospective, randomized, crossover trial, patients were blindly randomized to an intervention arm or a control arm. In accordance with the risk profile for the development of colorectal carcinoma, the study participants were divided into high-risk and low-risk groups. Individuals with just one criterion (age > 70 years, adenoma in medical history, and first-degree relative with colorectal cancer) were regarded as high-risk patients. Bowel preparation was performed in a standardized manner one day before the procedure. Participants in the intervention arm underwent an initial colonoscopy with sta…

AdenomaMalemedicine.medical_specialtyRandomizationendocrine system diseasesColorectal cancerColonoscopyTherapeutic irrigationColonic PolypsGroup BAdenomatous PolypsPredictive Value of TestsRisk FactorsMedicineHumansProspective StudiesDiagnostic ErrorsProspective cohort studyTherapeutic IrrigationEarly Detection of CancerAgedCross-Over Studiesmedicine.diagnostic_testbusiness.industryGastroenterologyGeneral MedicineColonoscopyEquipment DesignMiddle Agedmedicine.diseasePrognosisCrossover studydigestive system diseasesSurgerystomatognathic diseasesPredictive value of testsRandomized Controlled TrialFemalebusinessColorectal NeoplasmsWorld journal of gastroenterology
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Contribution of IL-17-producing {gamma}{delta} T cells to the efficacy of anticancer chemotherapy.

2011

IL-17 production by γδ T cells is required for tumor cell infiltration by IFN-γ–producing CD8+ T cells and inhibition of tumor growth in response to anthracyclines.

Adoptive cell transferMESH : AgedMESH : Equipment DesignCD8-Positive T-LymphocytesMESH: CatheterizationInterleukin-23MESH: Long-Term CareMice0302 clinical medicineMESH : CatheterizationT-Lymphocyte SubsetsMESH: NursingImmunology and Allergy[ SDV.IMM ] Life Sciences [q-bio]/ImmunologyInterferon gammaMESH: Quality of Health CareMESH: Professional Review OrganizationsMESH: AgedMESH : Gels0303 health sciencesMice Inbred BALB CCell DeathInterleukin-17MESH : Methylene BlueMESH : Quality of Health CareReceptors Antigen T-Cell gamma-deltaChemotherapy regimenMESH: Transplantation Autologous3. Good healthMESH: Cosmetic TechniquesTreatment Outcomemedicine.anatomical_structureMESH : Cadaver[SDV.IMM]Life Sciences [q-bio]/ImmunologyImmunogenic cell deathSarcoma ExperimentalInterleukin 17MESH : DissectionMESH : Long-Term CareMESH: Nursing CareMESH: Adipose Tissuemedicine.drugSignal TransductionMESH : Transplantation Autologous[SDV.IMM] Life Sciences [q-bio]/ImmunologyMESH : Feasibility StudiesMESH: GelsT cellMESH : MaleImmunologyMESH: DissectionAntineoplastic AgentsBiologyMESH : NursingMESH : Adipose TissueArticleMESH : Facial Muscles03 medical and health sciencesInterferon-gammaLymphocytes Tumor-InfiltratingImmune systemAntigenCell Line TumorMESH: Patient Care PlanningmedicineMESH: CadaverAnimalsMESH : Patient Care Planning030304 developmental biologyMESH: Humansbusiness.industryMESH: Facial MusclesT-cell receptorMESH : HumansCorrectionMESH: MaleMice Inbred C57BLMESH : Cosmetic TechniquesDoxorubicinImmunologyCancer researchMESH : Nursing CareMESH : Professional Review OrganizationsbusinessMESH: Feasibility StudiesCD8030215 immunologyMESH: Methylene BlueMESH: Equipment Design
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Alcohol consumption and risk of uterine myoma: A systematic review and meta analysis

2017

Background The published data about alcohol consumption and uterine myoma are scanty and controversial: some studies found positive association whereas other studies showed no association. Objectives To conduct a systematic review and meta-analysis to determine whether alcohol is a risk factor for myoma. Search strategy A MEDLINE/EMBASE search was carried out, supplemented by manual searches of bibliographies of the selected studies. Selection criteria Articles published as full-length papers in English. In the review we included all identified studies. Otherwise, the inclusion criteria for studies included in the meta-analysis were: a) case-control or cohort studies, reporting original dat…

Adult Alcohol Drinking Female Humans Middle Aged Myoma Odds Ratio Risk Factors Uterine Neoplasms Young Adultlcsh:MedicineSocial SciencesBiochemistryCohort StudiesMathematical and Statistical Techniques0302 clinical medicineRisk FactorsOdds RatioMedicine and Health SciencesPsychologyMedicinePublic and Occupational Health030212 general & internal medicinelcsh:Scienceeducation.field_of_studyAlcohol Consumption030219 obstetrics & reproductive medicineMultidisciplinaryObstetricsAlcoholic BeveragesBeerMiddle AgedResearch AssessmentAlcoholismSystematic reviewResearch DesignMeta-analysisUterine NeoplasmsPhysical SciencesFemaleStatistics (Mathematics)Research ArticleCohort studyAdultmedicine.medical_specialtyAlcohol DrinkingSystematic ReviewsSubstance-Related DisordersPopulationAddictionSubgroup analysisResearch and Analysis MethodsBeveragesYoung Adult03 medical and health sciencesMental Health and PsychiatryHumansStatistical MethodsRisk factoreducationNutritionbusiness.industrylcsh:RBiology and Life SciencesEstrogensMyomaOdds ratiomedicine.diseaseMyomaHormonesDietlcsh:QbusinessMathematicsMeta-AnalysisPLOS ONE
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Intervenciones individuales para mejorar la adherencia al tratamiento farmacéutico, la dieta y la actividad física en adultos con hipertensión primar…

2020

Introduction Hypertension is a chronic disease with 31% worldwide prevalence in adults. It has been associated with non-adherence to therapeutic regime with a negative impact on the prognosis of the disease and healthcare-associated costs. So, it is necessary to identify effective interventions to improve adherence among the afflicted population. The objective of this protocol is to describe the methods for a systematic review that will evaluate the effect of individual interventions so as to improve adherence to the prescribed pharmacological treatment, as well as to prescribed diet and physical activity in adults with primary hypertension. Methods and analysis A systematic search of studi…

Adult1683medicine.medical_specialtyhypertensionPopulationeducationPsychological interventionMEDLINEScopusCINAHLCardiovascular Medicineprimary careMeta-Analysis as TopicEpidemiologymedicineHumans1506educationExercisenutrition & dieteticsProtocol (science)education.field_of_studybusiness.industrypublic healthRGeneral MedicineDietSystematic reviewPharmaceutical PreparationsResearch DesignFamily medicineMedicineepidemiologyEnfermeríaEssential HypertensionbusinessSystematic Reviews as Topic
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Priming index of the Spanish word fragments from the Dasí, Soler, and Ruiz (2004) database

2007

Word-fragment completion is a frequently used test in implicit memory research. A database of 196 Spanish fragments was recently published (Dasi, Soler, & Ruiz, 2004) in which the fragments were described for indices, such as difficulty, familiarity, frequency, number of meanings, and so on (www.psychonomic.org/archive). In this work, a new index, thepriming index, is described for the same 196 fragments. This index is calculated for each fragment by subtracting the difficulty index (the proportion of correct completion when the fragment is not studied) from the proportion of correct completion when the fragment is studied, and it means the capacity of an item to be primed. In order to dete…

AdultAdolescentDatabaseAbstracting and IndexingComputer scienceExperimental and Cognitive Psychologycomputer.software_genreVocabularyDatabases as TopicArts and Humanities (miscellaneous)Index (publishing)Fragment (logic)MemoryResearch DesignSpainDevelopmental and Educational PsychologyHumansPsychology (miscellaneous)Implicit memorycomputerPriming (psychology)General PsychologyWord (group theory)Behavior Research Methods
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Motion-Cuing Algorithms

2015

Objective:The aim of this study was to characterize the human response to motion-cuing algorithms (MCAs) by comparing users’ perception to several proposed objective indicators.Background:Other researchers have proposed several MCAs, but few improvements have been achieved lately. One of the reasons for this lack of progress is that fair comparisons between different algorithms are hard to achieve, for their evaluation needs to be performed with humans and the tuning process is slow.Method:This characterization is performed by means of a comparison of the subjective perception of vehicle simulation users (90 participants) against several proposed objective indicators that try to measure MCA…

AdultAutomobile DrivingEngineeringInjury controlAccident preventionmedia_common.quotation_subjectPoison controlTransportationHuman Factors and ErgonomicsMotion (physics)MotionYoung AdultBehavioral NeurosciencePerceptionTask Performance and AnalysisHumansComputer SimulationMotion perceptionApplied Psychologymedia_commonbusiness.industryEquipment DesignMiddle AgedHuman engineeringAutomobile drivingPerceptionErgonomicsCuesbusinessAlgorithmAlgorithmsHuman Factors: The Journal of the Human Factors and Ergonomics Society
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Study protocol of the Diabetes and Depression Study (DAD): a multi-center randomized controlled trial to compare the efficacy of a diabetes-specific …

2013

Background Depression is common in diabetes and associated with hyperglycemia, diabetes related complications and mortality. No single intervention has been identified that consistently leads to simultaneous improvement of depression and glycemic control. Our aim is to analyze the efficacy of a diabetes-specific cognitive behavioral group therapy (CBT) compared to sertraline (SER) in adults with depression and poorly controlled diabetes. Methods/Design This study is a multi-center parallel arm randomized controlled trial currently in its data analysis phase. We included 251 patients in 70 secondary care centers across Germany. Key inclusion criteria were: type 1 or 2 diabetes, major depress…

AdultBlood GlucoseMaleResearch designmedicine.medical_specialtymedicine.medical_treatmentlaw.inventionGroup psychotherapyStudy ProtocolYoung AdultCognitionClinical ProtocolsRandomized controlled triallawGermanySertralineInternal medicineDiabetes mellitusHumansMedicineYoung adultPsychiatryDepression (differential diagnoses)AgedGlycemicGlycated HemoglobinDepressive Disorder MajorSertralineCognitive Behavioral Therapybusiness.industryMiddle Agedmedicine.diseaseAntidepressive AgentsPsychiatry and Mental healthDiabetes Mellitus Type 1Treatment OutcomeDiabetes Mellitus Type 2Research DesignPsychotherapy GroupFemalebusinessmedicine.drugBMC Psychiatry
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Impact of physical exercise on sensor performance of the FreeStyle Libre intermittently viewed continuous glucose monitoring system in people with Ty…

2019

AIMS To evaluate the sensor performance of the FreeStyle Libre intermittently viewed continuous glucose monitoring system using reference blood glucose levels during moderate-intensity exercise while on either full or reduced basal insulin dose in people with Type 1 diabetes. METHODS Ten participants with Type 1 diabetes [four women, mean ± sd age 31.4 ± 9.0 years, BMI 25.5±3.8 kg/m2 , HbA1c 55±7 mmol/mol (7.2±0.6%)] exercised on a cycle ergometer for 55 min at a moderate intensity for 5 consecutive days at the clinical research facility, while receiving either their usual or a 75% basal insulin dose. After a 4-week washout period, participants performed the second exercise period having sw…

AdultBlood GlucoseMalemedicine.medical_specialtyEndocrinology Diabetes and Metabolism030209 endocrinology & metabolismPhysical exerciseBiosensing Techniques03 medical and health sciencesYoung Adult0302 clinical medicineEndocrinologyInsulin Infusion SystemsInterquartile rangePredictive Value of TestsDiabetes mellitusInternal medicineInternal MedicinemedicineHumansInsulin030212 general & internal medicineExercise physiologyBlood Glucose MeasurementExerciseType 1 diabetesCross-Over StudiesDose-Response Relationship Drugbusiness.industryBlood Glucose Self-MonitoringEquipment Designmedicine.diseaseCrossover studyDiabetes Mellitus Type 1Equipment and SuppliesPredictive value of testsCardiologyFemalebusiness
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Curasan PRP kit vs. PCCS PRP system

2002

An important reason to improve methods of isolating platelet-rich plasma (PRP) is the potential use of autologous thrombocyte growth factors. In addition to discontinuous cell separation, two methods for extracting PRP that can be performed directly by the surgeon are now available. This study compared the suitability of these two methods for the preparation of PRP. Whole blood was drawn from 47 healthy donors (18 men, 29 women) aged 20-59 years (mean 29.9, SD 7.7). For each donor, PRP was separated by the PCCS method (PCCS Kit, 3i Implant Innovations, Palm Beach Gardens, FL, USA) and by the Curasan method (analogous to the PRP kit, Curasan, Kleinostheim, Germany). Thrombocyte counts differ…

AdultBlood PlateletsMaleMatched Pair AnalysisMatched-Pair AnalysisStatistics as TopicEfficiencyBuffy coatBiologyStatistics NonparametricInjectionsAndrologySex FactorsSex factorsThrombocyte countCatheterization PeripheralCell separationHumansPlateletGrowth SubstancesWhole bloodPlatelet CountSyringesPlateletpheresisAge FactorsAnticoagulantsEquipment DesignMiddle AgedNeedlesPlatelet-rich plasmaImmunologyFemaleOral SurgeryClinical Oral Implants Research
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