Search results for "DETA"

showing 10 items of 332 documents

Preparation of negative ion beams for the determination of the electron affinity of polonium by laser photodetachment

2021

A letter of intent submitted to the ISOLDE and Neutron-Time-of-flight Committee (INTC) at CERN to prepare the negative ion beam as a step towards measuring the electron affinity of polonium at CRIS (ISOLDE).

CRISelectron affinityPhysics::Accelerator Physicsnegative ionlaser photodetachment spectroscopyDetectors and Experimental TechniquesNuclear ExperimentpoloniumISOLDE
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Analysis of Antiproliferative and Chemosensitizing Effects of Sunitinib on Human Esophagogastric Cancer Cells: Synergistic Interaction With Vandetani…

2009

The receptor tyrosine kinases (RTKs), epidermal growth factor receptor (EGFR) and vascular endothelial growth factor receptor 1-3 (VEGFR1-3), are frequently expressed in gastric cancer and are putative therapeutic targets in this disease. We have investigated the anti-proliferative and chemosensitizing properties of the multitargeted small-molecule RTK inhibitors sunitinib and vandetanib in a panel of 4 human gastric and esophageal cancer cell lines. In the 1st instance, the expression of potential targets of these small-molecule inhibitors was examined by reverse transcriptase-polymerase chain reaction, western blotting, and flow cytometry. EGFR mRNA and protein was detected in all cases, …

Cancer ResearchUmbilical VeinsIndolesEsophageal NeoplasmsApoptosisVandetanibTyrosine-kinase inhibitorReceptor tyrosine kinasechemistry.chemical_compoundPiperidinesSunitinibMedicineDrug InteractionsEpidermal growth factor receptorPhosphorylationCells CulturedbiologySunitinibReverse Transcriptase Polymerase Chain ReactionDrug SynergismFlow CytometryErbB ReceptorsOncologyPhosphorylationDrug Therapy Combinationmedicine.drugSignal Transductionmedicine.medical_specialtymedicine.drug_classBlotting WesternAntineoplastic AgentsStomach NeoplasmsInternal medicineHumansPyrrolesPropidium iodideRNA MessengerProtein Kinase InhibitorsCell ProliferationVascular Endothelial Growth Factor Receptor-1business.industryCancermedicine.diseaseVascular Endothelial Growth Factor Receptor-3Vascular Endothelial Growth Factor Receptor-2EndocrinologychemistryCancer researchbiology.proteinQuinazolinesEndothelium VascularbusinessProto-Oncogene Proteins c-akt
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Modeling of biomolecular machines in non-equilibrium steady states

2021

Numerical computations have become a pillar of all modern quantitative sciences. Any computation involves modeling--even if often this step is not made explicit--and any model has to neglect details while still being physically accurate. Equilibrium statistical mechanics guides both the development of models and numerical methods for dynamics obeying detailed balance. For systems driven away from thermal equilibrium such a universal theoretical framework is missing. For a restricted class of driven systems governed by Markov dynamics and local detailed balance, stochastic thermodynamics has evolved to fill this gap and to provide fundamental constraints and guiding principles. The next step…

Chemical Physics (physics.chem-ph)Thermal equilibriumStatistical Mechanics (cond-mat.stat-mech)Markov chainComputer scienceComputationComplex systemDegrees of freedom (physics and chemistry)FOS: Physical sciencesGeneral Physics and AstronomyDetailed balanceStatistical mechanicsCondensed Matter - Soft Condensed MatterModels BiologicalMultiscale modelingPhysics - Chemical PhysicsThermodynamicsSoft Condensed Matter (cond-mat.soft)Statistical physicsPhysical and Theoretical ChemistryCondensed Matter - Statistical MechanicsThe Journal of Chemical Physics
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Una mañana en Oporto : apuntes de un viaje en la arquitectura de Álvaro Siza

2023

Per un architetto il viaggio è una impareggiabile occasione di studio, poiché permette di compiere una reale esperienza dello spazio, consente di valutare con i propri sensi ciò che altrimenti sarebbe sempre mediato dal disegno, dalla fotografia, dai testi o da altre rappresentazioni. La visita ad alcune architetture di Álvaro Siza, diviene occasione per una analisi critica e consente di estrarre alcune lezioni sul rapporto con i luoghi, sui caratteri dello spazio, sulla materialità, sull’impiego della luce, sul valore del dettaglio.

Composition Detail Materiality SpaceSettore ICAR/14 - Composizione Architettonica E Urbana
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Efficiently using connectivity information between triangles in a mesh for real-time rendering

2004

Triangle meshes are the most popular standard model used to represent polygonal surfaces. Drawing these meshes as a set of independent triangles involves sending a vast amount of information to the graphics system. Taking advantage of the connectivity information between the triangles in a mesh dramatically diminishes the amount of information the graphics system must handle. Multiresolution Triangle Strips (MTS) represent a triangle mesh as a collection of multiresolution triangles strips. These strips are the basis of both the storage and the rendering stage. The coherence between the extraction of two levels of detail is used in the model in order to decrease the visualisation time.

Computer Networks and CommunicationsComputer scienceComputer Science::Computational GeometryReal-time renderingVisualizationRendering (computer graphics)Computer Science::GraphicsHardware and ArchitectureComputer graphics (images)Triangle meshPolygonPolygon meshGraphicsInteractive visualizationSoftwareLevel of detailComputingMethodologies_COMPUTERGRAPHICSFuture Generation Computer Systems
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Non-equilibrium Markov state modeling of periodically driven biomolecules

2019

Molecular dynamics simulations allow to study the structure and dynamics of single biomolecules in microscopic detail. However, many processes occur on time scales beyond the reach of fully atomistic simulations and require coarse-grained multiscale models. While systematic approaches to construct such models have become available, these typically rely on microscopic dynamics that obey detailed balance. In vivo, however, biomolecules are constantly driven away from equilibrium in order to perform specific functions and thus break detailed balance. Here we introduce a method to construct Markov state models for systems that are driven through periodically changing one (or several) external p…

Computer scienceFOS: Physical sciencesGeneral Physics and AstronomyMarkov processMolecular Dynamics Simulation010402 general chemistry01 natural sciencesMolecular dynamicssymbols.namesake0103 physical sciencesPhysics - Biological PhysicsStatistical physicsPhysical and Theoretical ChemistryCondensed Matter - Statistical Mechanicschemistry.chemical_classificationQuantitative Biology::BiomoleculesStatistical Mechanics (cond-mat.stat-mech)010304 chemical physicsMarkov chainBiomoleculeMolecular biophysicsDetailed balanceDipeptidesComputational Physics (physics.comp-ph)Markov Chains0104 chemical sciencesModels ChemicalchemistryBiological Physics (physics.bio-ph)Benchmark (computing)symbolsState (computer science)Physics - Computational PhysicsThe Journal of Chemical Physics
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"Table 10" of "Studies of W boson plus jets production in p\bar{p} collisions at sqrt(s)=1.96 TeV"

2013

Differential production cross-section, normalized to the measured inclusive W boson cross-section, as a function of lepton pseudorapidity for events with two or more jets produced in association with a W boson. First uncertainty is statistical, second uncertainty is systematic.

Condensed Matter::Quantum GasesInclusiveSingle Differential Cross SectionDijet ProductionHigh Energy Physics::PhenomenologyPBAR P --> W+ JETS XPBAR P --> W- JETS XHigh Energy Physics::ExperimentDSIG/DETARAPJet Production1960.0W Production
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"Table 11" of "Studies of W boson plus jets production in p\bar{p} collisions at sqrt(s)=1.96 TeV"

2013

Differential production cross-section, normalized to the measured inclusive W boson cross-section, as a function of lepton pseudorapidity for events with three or more jets produced in association with a W boson. First uncertainty is statistical, second uncertainty is systematic.

Condensed Matter::Quantum GasesInclusiveSingle Differential Cross SectionHigh Energy Physics::PhenomenologyPBAR P --> W+ JETS XPBAR P --> W- JETS XHigh Energy Physics::ExperimentDSIG/DETARAPJet Production1960.0W Production
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"Table 9" of "Studies of W boson plus jets production in p\bar{p} collisions at sqrt(s)=1.96 TeV"

2013

Differential production cross-section, normalized to the measured inclusive W boson cross-section, as a function of lepton pseudorapidity for events with one or more jets produced in association with a W boson. First uncertainty is statistical, second uncertainty is systematic.

Condensed Matter::Quantum GasesInclusiveSingle Differential Cross SectionHigh Energy Physics::PhenomenologyPBAR P --> W+ JETS XPBAR P --> W- JETS XHigh Energy Physics::ExperimentDSIG/DETARAPJet Production1960.0W Production
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"Table 12" of "Studies of W boson plus jets production in p\bar{p} collisions at sqrt(s)=1.96 TeV"

2013

Differential production cross-section, normalized to the measured inclusive W boson cross-section, as a function of lepton pseudorapidity for events with four or more jets produced in association with a W boson. First uncertainty is statistical, second uncertainty is systematic.

Condensed Matter::Quantum GasesInclusiveSingle Differential Cross SectionHigh Energy Physics::PhenomenologyPBAR P --> W+ JETS XPBAR P --> W- JETS XHigh Energy Physics::ExperimentDSIG/DETARAPJet Production1960.0W Production
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