Search results for "DF"
showing 10 items of 1699 documents
The synovial joints of the human foot.
2007
The human foot is considered an organ with an assortment of tissues with different morphological characteristics and well defined limits, but effectively has a simple functionality when static that becomes extremely complex when in movement. Its complex structure, comprised of an elastic and resistant skin covering a bone framework, joints, muscles, tendons, veins and nerves, can be compared to an efficient mechanical assembly. After a long and extraordinary evolutive journey, the human foot has undergone numerous changes to perfect its function; it has lost most of its grabbing function whilst gaining new characteristics that have ultimately allowed the modern man to stand upright. The com…
Subglacial bedforms of the Zemgale Ice Lobe, south-eastern Baltic
2015
Abstract Presented in this paper are the results of the mapping of ∼6600 subglacial bedforms of the Zemgale Ice Lobe (ZIL), their composition and internal structure in the south-eastern Baltic region. Topographic maps at scale 1:10,000 were mainly used to map bedforms in Latvia, while a digital elevation model with cell size of 5 m was used for North Central Lithuania. The ZIL operated during the deglaciation of the Late Weichselian Scandinavian Ice Sheet (SIS), at least in the Middle Lithuanian and North Lithuanian glacial phases, and created a subglacial landform assemblage consisting of glacial lineations such as drumlins, mega-flutings, Mega Scale Glacial Lineations (MSGLs) and transver…
Linee guida attuali e future del trattamento dello scompenso cardiaco
2006
Extracts deriving from olive mill waste water and their effects on the liver of the goldfish Carassius auratus fed with hypercholesterolemic diet
2014
The present research aims to evaluate the beneficial effects of polyphenols derived from waste water from a olive mill, obtained by non-plastic molecular imprinting device, in a hypercholesterolemic diet on Carassius auratus, commonly known as goldfish that was selected as experimental model. The study was conducted with morphological and histochemical analyses and also the data were supported by immunohistochemical analysis. Results show the beneficial activity of polyphenols with a reduction of the damage in the steatotic group, confirming that they may be suggested in the treatment of diseases by lipid accumulation, and used as any addition in feed for farmed fish, in order to improve th…
GDF11 induces mild hepatic fibrosis independent of metabolic health
2020
BACKGROUND & AIMS: Growth Differentiation Factor 11 (GDF11) is an anti-aging factor, yet its role in liver diseases is not established. We evaluated the role of GDF11 in healthy conditions and in the transition from non-alcoholic fatty liver disease (NAFLD) to non-alcoholic steatohepatitis (NASH). RESULTS: GDF11 mRNA levels positively correlated with NAFLD activity score and with CPT1, SREBP, PPAR? and Col1A1 mRNA levels, and associated to portal fibrosis, in morbidly obese patients with NAFLD/NASH. GDF11-treated mice showed mildly exacerbated hepatic collagen deposition, accompanied by weight loss and without changes in liver steatosis or inflammation. GDF11 triggered ALK5-dependent SMAD2/…
Is recursion language-specific? Evidence of recursive mechanisms in the structure of intentional action
2014
In their 2002 seminal paper Hauser, Chomsky and Fitch hypothesize that recursion is the only human-specific and language-specific mechanism of the faculty of language. While debate focused primarily on the meaning of recursion in the hypothesis and on the human-specific and syntax-specific character of recursion, the present work focuses on the claim that recursion is language-specific. We argue that there are recursive structures in the domain of motor intentionality by way of extending John R. Searle's analysis of intentional action. We then discuss evidence from cognitive science and neuroscience supporting the claim that motor-intentional recursion is language-independent and suggest so…
Longitudinal study predicting burnout in Spanish nurses: The role of neuroticism and emotional coping
2019
Abstract The aim of the present study was to investigate whether nursing students' neuroticism trait and coping styles can predict nurses' professional burnout. A three-wave longitudinal study with a time lag of 6 years was conducted, following nursing students from three Spanish universities until they joined the health labor market. The sample consisted in 249 students in the first year of their nursing studies (T1), 199 at the end of their studies (T2), and 70 registered nurses three years after graduation (T3). Predictor variables were neuroticism, emotional and behavioural coping. Criterion variables were the three components of burnout (emotional exhaustion, despersonalization, and pe…
Anticancer Activity, Reduction Mechanism and G-Quadruplex DNA Binding of a Redox-Activated Platinum(IV)–Salphen Complex
2022
Aiming at reducing the unselective cytotoxicity of Pt(II) chemotherapeutics, a great deal of effort has been concentrated into the design of metal-containing drugs with different anticancer mechanisms of action. Inert Pt(IV) prodrugs have been proposed to be a valid alternative as they are activated by reduction directly into the cell releasing active Pt(II) species. On the other hand, a promising strategy for designing metallodrugs is to explore new potential biological targets rather than canonical B-DNA. G-quadruplex nucleic acid, obtained by self-assembly of guanine-rich nucleic acid sequences, has recently been considered an attractive target for anticancer drug design. Therefore, comp…
"Et cura vacare et negotio". Cicerone e la storiografia.
2012
Il "Brutus", la prima opera composta e fatta circolare da Cicerone dopo Farsàlo e il rientro a Roma, è un testo nel quale l’autore mette a fuoco il bisogno di conservare e trasmettere, dell’eloquenza romana, ciò che essa ha significato come modello di azione e di intervento nella realtà. In qualche misura, esso sembra configurarsi anche come un esperimento di narrazione storiografica, che risponde ai requisiti che Cicerone aveva considerato necessari per dedicarsi a tale attività nell’apertura del "de legibus".
A model to estimate daily albedo from remote sensing data : accuracy assessment of MODIS MCD43 product
2013
L’albedo superficial és un paràmetre físic que afecta al clima de la Terra i, a més, suposa una de les majors incerteses radiatives en l’actual modelització climàtica. Aquest paràmetre és molt variable tant a nivell espacial com temporal degut als canvis en les propietats de les superfícies i als canvis en les condicions d’il•luminació. En conseqüència, es requereix una resolució temporal diària de l’albedo per a realitzar estudis climàtics. L’augment de la resolució espacial dels models climàtics fa necessari l’estudi de les seues característiques espacials a nivell global. La teledetecció proporciona l’única opció pràctica de proporcionar dades d’albedo a nivell global amb alta qualitat i…