Search results for "DHE"
showing 10 items of 1975 documents
Análisis del comportamiento de materiales de restauración sometidos a un ensayo de microtracción
2022
Las restauraciones parciales adheridas son actualmente una alternativa terapéutica para resolver casos de pérdida de estructura dental, sea cual sea su origen, evitando de este modo, el empleo de coronas de recubrimiento completo. Para confeccionar estas restauraciones se ha usado de modo clásico la porcelana, pero en la última década han surgido una serie de materiales híbridos que se plantean como alternativa. Este estudio se ha realizado para analizar el comportamiento de diferentes materiales de restauración, en concreto para evaluar la resistencia adhesiva a un ensayo de microtracción. Material y Método: Se han evaluado una cerámica de silicatos de alta resistencia (IPS e.max CAD) y d…
The Psychological Risks Associated With the Non-medical Switch From Biologics to Biosimilars
2021
Biological products are therapeutic agents produced using a living system or organism. In many cases, access to these products is limited due to their expensive cost (Chow et al., 2011). A biosimilar is a biological product that is highly similar (not identic) to, and has no clinically meaningful differences from, an existing reference biological product on the market (Desai et al., 2020). “Non-medical” switching is the switching of a patient's medicine for reasons other than the patient's health and safety, like the reduction of costs (Dolinar et al., 2019).
Adherence to oral hormonal anticancer agents in breast cancer.
2022
There is an increasing trend towards using oral antitumoral agents in oncological patients. Compared to parenteral therapy, oral treatment offers convenience for both the patient and the healthcare system, with similar efficacy. However, the benefit deriving from oral drugs will be obtained only if patients adhere strictly to the treatment. Medical oncologists must therefore seek to optimize patient adherence. Breast cancer patients, particularly, are often treated with oral hormonal anticancer agents. In this review, we summarized evidence about adherence of breast cancer patients to oral hormonal anticancer agents and the consequences of poor compliance, the barriers to oral treatment an…
Influence of Oral Health Care Systems on Future Career Environment of Dental Students in Europe
2021
Oral healthcare is organized subsidiarily and independently by nation states in Europe and also within the EU and consequently, major differences between the nation states and the various oral healthcare systems in Europe are present. The socialization in the respective catchment area can have an impact on the job choice and the perception of employment opportunities of different professional groups. Therefore, the purpose of this survey was to elucidate the influence of different oral healthcare systems on students living or studying in the respective catchment area. A questionnaire (in English, French, German, Italian, and Spanish) with 18 different components was administered. Data on ge…
Estudio de la fuerza de adhesión de brackets metálicos y cerámicos sobre superficies de zircona tratadas con láser de femtosegundos
2017
Objetivos: 1) Analizar los estudios publicados sobre los efectos de diferentes láseres en la adhesión a superficies de cerámica; 2) determinar los parámetros ideales del láser de femtosegundos para conseguir una adhesión óptima bracket-zircona; 3) analizar los efectos del láser de femtosegundos en la fuerza de adhesión de brackets metálicos y cerámicos sobre zircona; comparar la fuerza de adhesión entre brackets cerámicos y metálicos a zircona. Material y métodos: El trabajo se dividió en tres partes. 1.Revisión sistemática de la literatura y meta-análisis para determinar qué tipo de láser es el más efectivo para adherir cementos y composites sobre superficies de cerámica. 2.Estudio in-vitr…
Cell-cycle control in cell-biomaterial interactions
2000
Current biocompatibility testing involves the demonstration of cell proliferation, which is usually interpreted as a sign of positive biocompatibility when the materials sustain cell proliferation. As the field of biomaterials research is rapidly moving toward tissue-engineered devices and hybrid organs, control of cell function has become a main topic. Cell function, which involves specific differentiation pathways, cannot be separated from cell-cycle control. The study of cell-cycle control is an important extension of routine proliferation assays and has extensive roots in developmental and tumor biology. We studied the expression of the tumour suppressor gene p53 and the proliferation-a…
Buccal Thin Films as Potent Permeation Enhancers for Cytisine Transbuccal Delivery
2022
Cytisine (CYT) is a powerful anti-smoking compound which could greatly benefit from transbuccal delivery because of both its unfavorable pharmacokinetics after oral administration and its intrinsic ability to permeate the buccal mucosa. This work aims to design CYT-loaded buccal thin films suitable for transbuccal drug delivery due to its capability of promoting the interaction between CYT and the buccal membrane. The solvent casting method was employed to prepare several thin films combining various excipients such as matrixing polymers, mucoadhesion agents, plasticizers and other compounds as humectants and sweeteners, component ratios and solvents. A total of 36 compositions was prepared…
Appropriateness of requests for human serum albumin at the University Hospital of Palermo, Italy: a prospective study
2015
Abstract OBJECTIVE: First, to assess the appropriateness of requests for albumin using current guidelines; second, to evaluate physicians' compliance with this protocol. DESIGN: Descriptive, prospective study. SETTING: 'Paolo Giaccone' University Hospital in Palermo (Italy). PARTICIPANTS: The six departments with the highest orders for albumin. INTERVENTION: An experimental, pharmacist-driven process for daily orders of albumin was activated over a period of 1 month. Pharmacy personnel handed out order forms on six different wards. Physicians were required to select one of a number of intended uses listed on the form. MAIN OUTCOME MEASURES: Data on albumin and serum protein levels; number o…
Microscratch testing method for systematic evaluation of the adhesion of atomic layer deposited thin films on silicon
2016
The scratch test method is widely used for adhesion evaluation of thin films and coatings. Usual critical load criteria designed for scratch testing of coatings were not applicable to thin atomic layer deposition (ALD) films on silicon wafers. Thus, the bases for critical load evaluation were established and the critical loads suitable for ALD coating adhesion evaluation on silicon wafers were determined in this paper as LCSi1, LCSi2, LCALD1, and LCALD2, representing the failure points of the silicon substrate and the coating delamination points of the ALD coating. The adhesion performance of the ALD Al2O3, TiO2, TiN, and TaCN+Ru coatings with a thickness range between 20 and 600 nm and dep…
Biocompatibility and Antibacterial Properties of ZnO-Incorporated Anodic Oxide Coatings on TiZrNb Alloy
2020
In a present paper, we demonstrate novel approach to form ceramic coatings with incorporated ZnO nanoparticles (NPs) on low modulus TiZrNb alloy with enhanced biocompatibility and antibacterial parameters. Plasma Electrolytic Oxidation (PEO) was used to integrate ZnO nanoparticles (average size 12&ndash