Search results for "DIABETES MELLITUS"
showing 10 items of 2077 documents
Eclectic Ocular Comorbidities and Systemic Diseases with Eye Involvement: A Review.
2016
Coexistence of several ocular diseases is more frequent than suspected. In spite of the refractive errors, one or more of the following can be detected simultaneously: glaucoma, cataracts, uveitis, age-related macular degeneration, and dry eyes. In addition, as people age, ocular comorbidities are much more usually seen. Specific diseases are openly acknowledged to affect the eyes and vision, such as diabetes mellitus, hypertension blood pressure, arthritis, hyperthyroidism, neurodegenerative disorders, hematologic malignancies, and/or systemic infections. Recent advances in early diagnosis and therapy of the ophthalmic pathologies have reinforced patient options to prevent visual impairmen…
Combined effects of aging and a pro-diabetic diet on retinal function in a murine model of aging of the human eye
2009
; Purpose: Improvement of life expectancy and changes in the dietary behaviour of developed populations are accompanied with the prevalence of diabetes and age-related ocular pathologies. Aging of the retina is characterized by accumulation of lipids at the basement of the retinal pigment epithelium - Bruch’s membrane complex.Meanwhile increased oxidative stress is one of the features of aging and diabetes. A fructose-rich diet induces insulin resistance and hypertriglyceridemia, mimicking diabetes. The goal of our study was to evaluate the effects of a pro-diabetic fructose-enriched diet on the retinal function of the ApoB100,LDLR-/- mice, a murine model of aging of the human eye. Methods…
Knowledge about diabetes mellitus among Polish medical students
2020
Introduction. Due to high prevalence of diabetes mellitus all over the world it is essential for students who will become doctors of different specialties to possess a basic knowledge of it in this field. This pilot surveybased study was designed to assess diabetes related knowledge among faculty of medicine students from all of the medical universities in Poland. Materials and methods. Students were invited to fulfill the questionnaire during Students’ Diabetology Conference and via the Internet (social media). The survey consisted of questions about respondent’s age and personal history of diabetes and diabetes related knowledge (etiology, symptoms, risk factors, complications and treatme…
Videocapillaroscopy of the Oral Mucosa in Patients with Diabetic Foot: Possible Diagnostic Role of Microangiopathic Damage?
2020
Introduction: Diabetic foot represents one of the most serious and expensive complications of diabetes and is subject to a high percentage of amputations that are almost always preceded by ulcers ascribable to neuropathy and/or vasculopathy. Videocapillaroscopy (VCS) can be a valuable aid in order to uncover morpho-structural anomalies in the vascular bed, both at the level of the oral mucosa and at the level of the terminal vessels of the lower limb. Materials and methods: Sixty subjects divided into 4 groups were enrolled: 15 healthy subjects; 15 patients with diabetes for more than 10 years without ulcerative foot lesions; 15 patients with neuropathic diabetic foot (clinical diagnosis, M…
Nephroprotection by Hypoglycemic Agents: Do We Have Supporting Data?
2015
Current therapy directed at delaying the progression of diabetic nephropathy includes intensive glycemic and optimal blood pressure control, renin angiotensin-aldosterone system blockade and multifactorial intervention. However, the renal protection provided by these therapeutic modalities is incomplete. There is a scarcity of studies analysing the nephroprotective effect of antihyperglycaemic drugs beyond their glucose lowering effect and improved glycaemic control on the prevention and progression of diabetic nephropathy. This article analyzes the exisiting data about older and newer drugs as well as the mechanisms associated with hypoglycemic drugs, apart from their well known blood gluc…
Metabolic Aspects of Migraine: Association With Obesity and Diabetes Mellitus
2021
Migraine is a disabling neurovascular disorder, characterized by moderate to severe unilateral headaches, nausea, photophobia, and/or phonophobia, with a higher prevalence in women than in men, which can drastically affect the quality of life of migraine patients. In addition, this chronic disorder is related with metabolic comorbidities associated with the patient's lifestyle, including obesity and diabetes mellitus (DM). Beyond the personal and socioeconomic impact caused by migraine, obesity and DM, it has been suggested that these metabolic disorders seem to be related to migraine since: (i) they are a risk factor for developing cardiovascular disorders or chronic diseases; (ii) they ca…
0102: Atherogenic lipid profile and lipid peroxide products of patients with rheumatoid arthritis
2016
IntroductionRheumatoid Arthritis (RA) is a chronic relapsing immune-inflammatory multisystem disease with predominant synovial proliferation and destruction of articular cartilage. Patients with RA have a higher riskof mortality related to increased risk of cardiovascular disease with atherogenic lipid profile. In recent years, oxidative stress in RA patients has received considerable attention and has been implicated as mediators of tissue damage and cardio-vascular disease in patients with RA.The aim of the present study was to assess the lipid profile and lipid peroxide products of patients with rheumatoid arthritis compared with healthy controls.Patients and MethodsThe study included 70…
Mucormycosis of maxillary sinus in a newly diagnosed case of diabetes mellitus
2019
Rhinocerebral mucormycosis is the third most common fungal infection after aspergillosis and candidiasis. The importance of mucormycosis has grown in recent years, as the number of patients has increased dramatically. Herein, we present a case of a newly diagnosed patient of diabetes mellitus having ulcerated palate and destruction of maxillary sinus evident on computed tomography scan. A biopsy report was suggestive of mucormycosis. Aggressive medical and surgical treatment was done along with the treatment of diabetes mellitus.
Prognostic impact of hypertension and carotid lesions in a five years follow-up
2005
PO-58 - Cardiovascular risk profile in survivors of adult cancer - results from the general population study.
2016
The advancements in cancer treatment and detection of early cancer have resulted in steady increase of adult cancer survivors over the years. However, due to the long term toxic effects of chemotherapy and radiotherapy, the incidence of cardiovascular diseases (CVD) is increasing in survivors. Identifying risk factors and interventions to reduce the excess burden of CVD in this vulnerable population is urgently needed.To investigate the cardiovascular risk factors (CVRFs), inflammation and coagulation profile in cancer survivors from a large population-based study.Presence of CVRFs and laboratory markers have been compared in individuals with (n=1,359) and without (n=13,626) history of canc…