Search results for "DICS"
showing 10 items of 2714 documents
A cell-free approach with a supporting biomaterial in the form of dispersed microspheres induces hyaline cartilage formation in a rabbit knee model
2020
The objective of this study was to test a regenerative medicine strategy for the regeneration of articular cartilage. This approach combines microfracture of the subchondral bone with the implant at the site of the cartilage defect of a supporting biomaterial in the form of microspheres aimed at creating an adequate biomechanical environment for the differentiation of the mesenchymal stem cells that migrate from the bone marrow. The possible inflammatory response to these biomaterials was previously studied by means of the culture of RAW264.7 macrophages. The microspheres were implanted in a 3 mm-diameter defect in the trochlea of the femoral condyle of New Zealand rabbits, covering them wi…
Pharmacokinetics of methylmethacrylate monomer during total hip replacement in man.
1988
The concentration of methylmethacrylate monomer (MMA) in the blood stream after implantation of the components of 15 total hip prostheses using bone cement was determined in the pulmonary artery, the radial artery, and the superior vena cava after cement application, and correlated with the observed drop in blood pressure and the increase in the pulmonary arterial pressure. In all samples MMA was found. The values ranged from 0.02 micrograms/ml to 59 micrograms/ml. The mean maximum value after implantation of the stem was measured to be 7.8 micrograms/ml in the pulmonary artery, 4.6 micrograms/ml in the radial artery, and 1.75 micrograms/ml in the superior vena cava. After implantation of t…
Risk factors for incidental durotomy during posterior open spine surgery for degenerative diseases in adults: A multicenter observational study.
2017
Incidental durotomy (ID) is a common intraoperative complication of spine surgery. It can lead to persistent cerebrospinal fluid leakage, which may cause serious complications, including severe headache, pseudomeningocele formation, nerve root entrapment, and intracranial hemorrhage. As a result, it contributes to higher healthcare costs and poor patient outcomes. The purpose of this study was to clarify the independent risk factors that can cause ID during posterior open spine surgery for degenerative diseases in adults. We conducted a prospective multicenter study of adult patients who underwent posterior open spine surgery for degenerative diseases at 10 participating hospitals from July…
Cortical bone thickening in Type A posterior atlas arch defects: experimental report.
2017
Abstract Background Context To date, no information about the cortical bone microstructural properties in atlas vertebrae with posterior arch defects has been reported. Purpose To test if there is an increased cortical bone thickening in atlases with Type A posterior atlas arch defects in an experimental model. Study Design Micro-computed tomography (CT) study on cadaveric atlas vertebrae. Methods We analyzed the cortical bone thickness, the cortical volume, and the medullary volume (SkyScan 1172 Bruker micro-CT NV, Kontich, Belgium) in cadaveric dry vertebrae with a Type A atlas arch defect and normal control vertebrae. Results The micro-CT study revealed significant differences in cortica…
Microsurgical fenestration of perineural cysts to the thecal sac at the level of the distal dural sleeve
2011
Background Surgery for symptomatic sacral perineural cysts remains an issue of discussion. Assuming micro-communications between the cyst and thecal sac resulting in a valve mechanism and trapping of CSF as a pathomechanism, microsurgical fenestration from the cyst to the thecal sac was performed to achieve free CSF communication. Methods In 13 consecutive patients (10 female, 3 male), MRI revealed sacral perineural cysts and excluded other pathologies. Micro-communication between the thecal sac and the cysts was shown by delayed contrast filling of the cysts on postmyelographic CT. Surgical fenestration achieved free CSF communication between the thecal sac and cysts in all patients. The p…
Association of Monocarboxylate Transporter-1 (MCT1) A1470T Polymorphism (rs1049434) with Forward Football Player Status.
2018
AbstractThe aim of this study was to investigate the association between the MCT1 (monocarboxylate transporter 1) A1470T polymorphism and positional roles in a large cohort of professional football players from five different countries. We compared genotype distributions of the MCT1 A1470T polymorphism between football players (n=694) and non-athlete controls (n=781) from Italy, Poland, Lithuania, Ukraine and Malta, and we analyzed the MCT1 genotype distributions with respect to the players’ positions in the field (e. g. forwards, midfielders, defenders and goalkeepers). Genomic DNA was extracted from either buccal epithelium or peripheral blood using a standard protocol. In the pooled coho…
Multiple representations and mechanisms for visuomotor adaptation in young children
2012
International audience; In this study, we utilized transformed spatial mappings to perturb visuomotor integration in 5-yr-old children and adults. The participants were asked to perform pointing movements under five different conditions of visuomotor rotation (from 0° to 180°), which were designed to reveal explicit vs. implicit representations as well as the mechanisms underlying the visual-motor mapping. Several tests allowed us to separately evaluate sensorimotor (i.e., the dynamic dimension of movement) and cognitive (i.e., the explicit representations of target position and the strategies used by the participants) representations of visuo-proprioceptive distortion. Our results indicate…
Motor competence, perceived physical competence, physical fitness, and physical activity within Finnish children
2019
The purpose of this study was to investigate reciprocal relationships among students’ motor competence (MC) (leaping, throwing, catching, jumping skills), perceived physical competence, health‐related fitness (HRF) (20 m shuttle run, push‐up, abdominal muscles endurance tests) and objectively measured moderate‐to‐vigorous physical activity (MVPA). Participants included 422 Grade 5 Finnish children (246 girls). Two separate structural equation models investigated paths (a) from MC through both perceived physical competence and HRF to MVPA, and (b) from MVPA through both perceived physical competence and HRF to MC. Model 1 demonstrated an indirect path from MC through HRF to MVPA and a direct…
Adiposity, physical activity and neuromuscular performance in children
2016
We investigated the associations of body fat percentage, objectively assessed moderate-to-vigorous physical activity (MVPA), and different types of physical activity assessed by a questionnaire with neuromuscular performance. The participants were 404 children aged 6–8 years. Body fat percentage (BF%) was assessed using dual-energy x-ray absorptiometry and physical activity by combined heart rate and movement sensing and a questionnaire. The results of 50-metre shuttle run, 15-metre sprint run, hand grip strength, standing long jump, sit-up, modified flamingo balance, box and block, and sit-and-reach tests were used as measures of neuromuscular performance. Children who had a combination of…
Polygenic Risk Scores and Physical Activity
2020
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