Search results for "DIEP"
showing 10 items of 14 documents
Re-definition and supporting evidence toward Fanconi Anemia as a mitochondrial disease: Prospects for new design in clinical management
2021
Fanconi anemia (FA) has been investigated since early studies based on two definitions, namely defective DNA repair and proinflammatory condition. The former definition has built up the grounds for FA diagnosis as excess sensitivity of patients' cells to xenobiotics as diepoxybutane and mitomycin C, resulting in typical chromosomal abnormalities. Another line of studies has related FA phenotype to a prooxidant state, as detected by both in vitro and ex vivo studies. The discovery that the FA group G (FANCG) protein is found in mitochondria (Mukhopadhyay et al., 2006) has been followed by an extensive line of studies providing evidence for multiple links between other FA gene products and mi…
Salvage (tertiary) breast reconstruction after implant failure
2011
Summary Background Salvage breast reconstruction is defined as a complete revision of a previous reconstruction in case of unsatisfactory results or failure of primary or secondary breast reconstruction. We have termed this ‘tertiary breast reconstruction'. This article presents our experience with tertiary reconstructions, including the indications, method of reconstruction and outcomes. Methods A retrospective note review was performed for all patients who underwent breast reconstruction with autologous tissue under one surgeon between 2002 and 2009 at the University Hospital, Ghent. Out of these 688 patients, 54 patients (7.8%) required tertiary surgery with autologous tissue after failu…
Bilateral DIEP Flap Breast Reconstruction to a Single Set of Internal Mammary Vessels: Technique, Safety, and Outcomes after 250 Flaps.
2019
BACKGROUND: The deep inferior epigastric artery perforator (DIEP) flap is considered the gold standard in autologous breast reconstruction. In bilateral cases, both flaps are often anastomosed to the internal mammary vessels on either side of the sternum. The authors propose a method in which both flaps are anastomosed to only the right side internal mammary artery and vein. METHODS: Between November of 2009 and March of 2018, 125 patients underwent bilateral DIEP flap breast reconstruction with this technique. One flap is perfused by the anterograde proximal internal mammary artery and the second one by the retrograde distal internal mammary artery after presternal tunneling. Patient demog…
Fanconi anemia (FA) and crosslinker sensitivity: Re-appraising the origins of FA definition
2015
The commonly accepted definition of Fanconi anemia (FA) relying on DNA repair deficiency is submitted to a critical review starting from the early reports pointing to mitomycin C bioactivation and to the toxicity mechanisms of diepoxybutane and a group of nitrogen mustards causing DNA crosslinks in FA cells. A critical analysis of the literature prompts revisiting the FA phenotype and crosslinker sensitivity in terms of an oxidative stress (OS) background, redox-related anomalies of FA (FANC) proteins, and mitochondrial dysfunction. This re-appraisal of FA basic defect might lead to innovative approaches both in elucidating FA phenotypes and in clinical management.
Charles Nodier, Trilogie écossaise
2013
Charles Nodier’s summer ambulations through Scotland in 1821 were to spawn a genre: the romantic travelogue. The reader is invited on a journey through age-old legends and oneiric cartography, through the fogs of ancient Caledonia and modern Scotland, and into the land of goblins and fairies.
Different Hydraulic Constructs to Optimize the Venous Drainage of DIEP Flaps in Breast Reconstruction: Decisional Algorithm and Review of the Literat…
2020
Venous congestion is the most common perfusion-related complication of deep inferior epigastric artery perforator (DIEP) flap. Several hydraulic constructs can be created for venous superdrainage in case of flap venous engorgement or as a preventive measure. These can be classified based on the choice of the draining vein of the flap, either a second deep inferior epigastric vein (DIEV) or a superficial inferior epigastric vein (SIEV), and of the recipient vein, either a vein of the chest or the DIEV. Background Venous congestion is the most common perfusion-related complication of deep inferior epigastric artery perforator (DIEP) flap. Several hydraulic constructs can be created for venou…
Du comté d'Argyle au royaume de Saba : Nodier et l'Écosse des origines
2011
Autre compte rendu d'Hélène Védrine (revue Romantisme) : "L’article de Sébastien Vacelet continue cette réflexion sur l’écriture viatique et son rapport à l’espace, en s’intéressant à la trilogie écossaise de Nodier : Promenade de Dieppe aux montagnes d’Écosse, Trilby et La Fée aux miettes. Cet article extrêmement renseigné – Sébastien Vacelet est l’auteur d’une thèse sur l’Écosse des romantiques dirigée par Georges Zaragoza et a organisé à Dijon une récente journée d’études sur le même thème qui fera l’objet du volume 3 des Cahiers d’études nodiéristes – montre comment les connaissances historiques et livresques de Nodier sur l’Écosse servent à bâtir une fiction des origines qui gomme les …
Sur la francisation d’un toponyme écossais : l’« Argail » de Charles Nodier
2011
International audience; This study opposes, on the one hand, the concept exposed by linguist and theoretician Charles Nodier (1780-1844) in his Elementary Notions in Linguistics (1834) referring to the inalterable spelling of proper nouns, and, on the other hand, his practice as a storyteller and creator in his Trilby (1822). We will also consider answering the question of the gallicization of the toponym "Argyle" (allusion to the lake region in Scotland), spelled "Argail" by Nodier in his tale, contrary to all expectations. "Argail" , beyond the mere process of transliteration and trompe-l’oeil justifications revealed by Nodier himself in the preface of his book, opens up to subtle manipul…
CCDC 942767: Experimental Crystal Structure Determination
2014
Related Article: Chi G. Fru, Louis P. Sandjo, Victor Kuete, Johannes C. Liermann, Dieter Schollmeyer, Samuel O. Yeboah, Renameditswe Mapitse, Berhanu M. Abegaz, Bonaventure T. Ngadjui, Till Opatz|2013|Phytochem.Lett.|6|676|doi:10.1016/j.phytol.2013.08.017
Porcine Model for Deep Superior Epigastric Artery Perforator Flap Harvesting: Anatomy and Technique
2018
BACKGROUND Microsurgical training on rats before starting with clinical practice is a well-established routine. Animal model training is less widespread for perforator flaps, although these flaps represent a technical challenge. Unlike other flaps, they require specific technical skills that need to be adequately trained on a living model 1 : a cadaver is not enough because no bleeding, vessel damage, or vasospasm can be simulated. 2 The purpose of this study was to assess the suitability of the porcine abdomen as a training model for the deep inferior epigastric artery perforator (DIEAP) flap, commonly used in human breast reconstruction. METHODS A female swine (Sus scrofa domesticus, ssp;…