Search results for "DISEASE"

showing 10 items of 52575 documents

Evolutionary relationships between digeneans of the family Brachycladiidae Odhner, 1905 and their marine mammal hosts: A cophylogenetic study.

2016

Cophylogenetic studies examine the congruence between host and parasite phylogenies. There are few studies that quantify the relative contribution of coevolutionary events, i.e. duplication, loss, failure-to-diverge, host-switching and spreading in trophically-transmitted parasites at the marine realm. We addressed this issue in the Brachycladiidae, a cosmopolitan digenean family specific to marine mammals. We used, for the first time, distance-based and event-based methods to explicitly test the coevolutionary events that have shaped the current brachycladiid-marine mammal associations. Parasite phylogeny was constructed using mtDNA ND3 sequences of nine brachycladiid species, and host phy…

0106 biological sciences0301 basic medicineMitochondrial DNAAquatic OrganismsBiology010603 evolutionary biology01 natural sciencesDNA MitochondrialDigeneaHost-Parasite Interactions03 medical and health sciencesSpecies SpecificityPhylogeneticsAnimalsPhylogenyMammalsCytochrome bHost (biology)EcologySequence Analysis DNACytochromes bbiology.organism_classificationBiological Evolution030104 developmental biologyInfectious DiseasesTaxonEvolutionary biologyDelphinoideaParasitologyMammalTrematodaParasitology international
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Root growth compensates for molar wear in adult goats (Capra aegagrus hircus)

2018

One reason for the mammalian clade’s success is the evolutionary diversity of their teeth. In herbivores, this is represented by high‐crowned teeth evolved to compensate for wear caused by dietary abrasives like phytoliths and grit. Exactly how dietary abrasives wear teeth is still not understood completely. We fed four different pelleted diets of increasing abrasiveness (L: Lucerne; G: grass; GR: grass and rice husks; GRS: grass, rice husks, and sand) to four groups of a total of 28 adult goats, all with completely erupted third molars, over a six‐month period. Tooth morphology was captured by medical computed tomography scans at the beginning and end of the controlled feeding experiment, …

0106 biological sciences0301 basic medicineMolarRoot growthPhysiologyCapra aegagrusBiology010603 evolutionary biology01 natural sciencesMandibular second molar03 medical and health sciencesAnimal sciencestomatognathic systemGeneticsmedicineCementumRoot volumeMolecular BiologyEcology Evolution Behavior and Systematics2. Zero hungerHerbivorestomatognathic diseases030104 developmental biologymedicine.anatomical_structureVolume (thermodynamics)Animal Science and ZoologyJournal of Experimental Zoology Part A: Ecological and Integrative Physiology
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Responses of marine mussel Mytilus galloprovincialis (Bivalvia: Mytilidae) after infection with the pathogen Vibrio splendidus

2019

International audience; Bivalve molluscs possess effective cellular and humoral defence mechanisms against bacterial infection. Although the immune responses of mussels to challenge with pathogenic vibrios have been largely investigated, the effects at the site of injection at the tissue level have not been so far evaluated. To this aim, mussels Mytilus galloprovincialis were herein in vivo challenged with Vibrio splendidus to assess the responses induced in hemolymph and posterior adductor muscle (PAM), being the site of bacterial infection. The number of living intra-hemocyte bacteria increased after the first hour post-injection (p.i.), suggesting the occurrence of an intense phagocytosi…

0106 biological sciences0301 basic medicineMuscle tissueanimal structuresPhysiologyHealth Toxicology and Mutagenesis[SDV]Life Sciences [q-bio]Osmotic balanceBivalve molluscs; Cell turnover; Hemolymph; In vivo infection; Osmotic balance; Pathogenic bacteria; Posterior adductor muscleToxicologymedicine.disease_cause01 natural sciencesBiochemistry[SDV.IMM.II]Life Sciences [q-bio]/Immunology/Innate immunityMicrobiologyIn vivo infection03 medical and health sciencesImmune systemHemolymphHemolymphmedicineAnimals14. Life underwaterBivalve molluscVibrioMytilusbiology010604 marine biology & hydrobiologyfungiPathogenic bacteriaCell BiologyGeneral MedicineMusselWater-Electrolyte Balancebiology.organism_classificationBivalviaBivalve molluscsPosterior adductor muscleMytilus030104 developmental biologymedicine.anatomical_structureMytilidae13. Climate actionPathogenic bacteriaHost-Pathogen InteractionsCell turnover[SDV.IMM]Life Sciences [q-bio]/Immunology
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Expression of the Intracellular COPT3-Mediated Cu Transport Is Temporally Regulated by the TCP16 Transcription Factor

2018

[EN] Copper is an essential element in plants. When scarce, copper is acquired from extracellular environment or remobilized from intracellular sites, through members of the high affinity copper transporters family COPT located at the plasma membrane and internal membrane, respectively. Here, we show that COPT3 is an intracellular copper transporter, located at a compartment of the secretory pathway, that is mainly expressed in pollen grains and vascular bundles. Contrary to the COPT1 plasma membrane member, the expression of the internal COPT3 membrane transporter was higher at 12 h than at 0 h of a neutral photoperiod day under copper deficiency. The screening of a library of conditionall…

0106 biological sciences0301 basic medicineMutantchemistry.chemical_elementPlant Sciencelcsh:Plant culture01 natural sciencesTCP1603 medical and health sciencesTranscriptional regulationGene expressionBIOQUIMICA Y BIOLOGIA MOLECULARExtracellularmedicinelcsh:SB1-1110COPT3transcriptional regulationheavy metalsTranscription factorSecretory pathwayOriginal ResearchCopper transportmedicine.diseaseCopperCell biology030104 developmental biologyHeavy metalschemistrycopper transportCopper deficiencyIntracellular010606 plant biology & botanyFrontiers in Plant Science
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An Arabidopsis Mutant Over-Expressing Subtilase SBT4.13 Uncovers the Role of Oxidative Stress in the Inhibition of Growth by Intracellular Acidificat…

2020

Intracellular acid stress inhibits plant growth by unknown mechanisms and it occurs in acidic soils and as consequence of other stresses. In order to identify mechanisms of acid toxicity, we screened activation-tagging lines of Arabidopsis thaliana for tolerance to intracellular acidification induced by organic acids. A dominant mutant, sbt4.13-1D, was isolated twice and shown to over-express subtilase SBT4.13, a protease secreted into endoplasmic reticulum. Activity measurements and immuno-detection indicate that the mutant contains less plasma membrane H+-ATPase (PMA) than wild type, explaining the small size, electrical depolarization and decreased cytosolic pH of the mutant but not orga…

0106 biological sciences0301 basic medicineMutantmedicine.disease_cause01 natural sciencesCatalysisInorganic Chemistrylcsh:ChemistryH<sup>+</sup>-ATPase03 medical and health sciencesorganic acidsmedicinePhysical and Theoretical ChemistryMolecular Biologylcsh:QH301-705.5Spectroscopychemistry.chemical_classificationReactive oxygen speciesNADPH oxidasebiologyNADPH oxidaseEndoplasmic reticulumOrganic ChemistryWild typeROSGeneral MedicineComputer Science ApplicationsCell biology030104 developmental biologychemistrylcsh:Biology (General)lcsh:QD1-999biology.proteinactivation-taggingIntracellularOxidative stress010606 plant biology & botanyOrganic acidInternational Journal of Molecular Sciences
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Effects of transgenic expression of Brevibacterium linens methionine gamma lyase (MGL) on accumulation of Tylenchulus semipenetrans and key aminoacid…

2017

Key message Carrizo transgenic plants overexpressing methionine-gamma-lyase produced dimethyl sulfide. The transgenic plants displayed more resistance to nematode attacks (Tylenculus semipenetrans) and may represent an innovative strategy for nematode control. Abstract Tylenchulus semipenetrans is a nematode pest of many citrus varieties that causes extensive damage to commercial crops worldwide. Carrizo citrange vr. (Citrus sinensis L. Usb × Poncirus trifoliate L. Raf) plants overexpressing Brevibacterium linens methionine-gamma-lyase (BlMGL) produced the sulfur volatile compound dimethyl sulfide (DMS). The aim of this work was to determine if transgenic citrus plants expressing BlMGL show…

0106 biological sciences0301 basic medicineNematodesPlant BiologyPlant ScienceGenetically modified crops01 natural sciencesPlant Rootschemistry.chemical_compoundMethionineMethionine gamma lyaseBrevibacteriumAmino AcidsNematodeCitrus sinensibiologySulfur volatilefood and beveragesGeneral MedicinePlantsPlants Genetically ModifiedTylenchulus semipenetransAmino AcidHorticultureCarbon-Sulfur LyasesBiochemistryCarbon-Sulfur LyasePlant LeaveCitrus × sinensisCitrus sinensisTylenchidaMethionine gamma-lyaseSulfideTransgenePlant Biology & BotanyPlant DiseaseGenetically ModifiedSulfidesArticle03 medical and health sciencesGeneticSulfur volatilesGeneticsAnimalsPlant DiseasesMethionineAnimalfungiPlant RootBrevibacteriumbiology.organism_classificationBrain DisordersPlant Leaves030104 developmental biologychemistryGlycineBiochemistry and Cell BiologyAgronomy and Crop Science010606 plant biology & botany
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Females pay the oxidative cost of dominance in a highly social bird.

2018

12 pages; International audience; Understanding the evolution and maintenance of social behaviour requires a better understanding of the physiological mechanisms underlying the trade-offs between the benefits and costs of social status. Social dominance is expected to provide advantages in terms of access to resources and to reproduction but acquiring and maintaining dominance may also entail physiological costs. Dominant individuals are likely to engage more frequently in aggressive behaviours and/or may allocate a substantial amount of energy and resources to signal their status. Hence, dominance is likely to involve multiple physiological processes that stimulate aerobic metabolism and l…

0106 biological sciences0301 basic medicineOXYsocial dominanceOxidative phosphorylationSocial behaviourBiologyphysiological costsTrade-offmedicine.disease_cause010603 evolutionary biology01 natural sciences03 medical and health sciencesFemale healthmedicineoxidative stressEcology Evolution Behavior and Systematicstrade-offPhiletairus socius030104 developmental biologyDominance (ethology)AgeingROMsAnimal Science and Zoology[SDE.BE]Environmental Sciences/Biodiversity and EcologyOxidative stressDemographySocial status[SDV.EE.IEO]Life Sciences [q-bio]/Ecology environment/Symbiosis
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Barcoding of parasitoid wasps (Braconidae and Chalcidoidea) associated with wild and cultivated olives in the Western Cape of South Africa

2019

Wild and cultivated olives harbor and share a diversity of insects, some of which are considered agricultural pests, such as the olive fruit fly. The assemblage of olive-associated parasitoids and seed wasps is rich and specialized in sub-Saharan Africa, with native species possibly coevolving with their hosts. Although historical entomological surveys reported on the diversity of olive wasp species in the Western Cape Province of South Africa, no comprehensive study has been performed in the region in the molecular era. In this study, a dual approach combining morphological and DNA-based methods was used for the identification of adult specimens reared from olive fruits. Four species of B…

0106 biological sciences0301 basic medicineOlive fruit flyWaspsParasitismmedicine.disease_cause010603 evolutionary biology01 natural sciencesDNA barcodingParasitoid03 medical and health sciencesSouth AfricaOleaBotanyInfestationGeneticsmedicineAnimalsDNA Barcoding TaxonomicMolecular BiologyPhylogenybiologyfungiGeneral MedicineBiodiversityDNAbiology.organism_classification030104 developmental biologyGenetic distanceTaxonomy (biology)BraconidaeBiotechnologyGenome
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Cultivar- and Wood Area-Dependent Metabolomic Fingerprints of Grapevine Infected by Botryosphaeria Dieback

2020

International audience; Botryosphaeria dieback is one of the most significant grapevine trunk diseases that affects the sustainability of the vineyards and provokes economic losses. The causal agents, Botryosphaeriaceae species, live in and colonize the wood of the perennial organs causing wood necrosis. Diseased vines show foliar symptoms, chlorosis, or apoplexy, associated to a characteristic brown stripe under the bark. According to the susceptibility of the cultivars, specific proteins such as PR-proteins and other defense-related proteins are accumulated in the brown stripe compared with the healthy woody tissues. In this study, we enhanced the characterization of the brown stripe and …

0106 biological sciences0301 basic medicinePerennial plant[SDV]Life Sciences [q-bio]Plant Science01 natural sciences03 medical and health sciencesMetabolomicsAscomycotaMetabolomicsVitisCultivarBotryosphaeriaPlant DiseasesChlorosisbiologyfood and beveragesBotryosphaeriaceaebiology.organism_classificationWoodHorticulture030104 developmental biologyPhytochemicalvisual_artvisual_art.visual_art_mediumBarkAgronomy and Crop Science010606 plant biology & botanyPhytopathology®
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Impact of gas emboli and hyperbaric treatment on respiratory function of loggerhead sea turtles (Caretta caretta)

2018

We investigated lung function in bycaught sea turtles with and without gas emboli. Hyperbaric O2 treatment significantly improves lung function. Pulmonary function testing may be a useful diagnostic tool to assess fisheries induced trauma.

0106 biological sciences0301 basic medicinePhysiologyRespiratory Medicine and AllergyManagement Monitoring Policy and Lawdecompression sicknesscomparative physiology010603 evolutionary biology01 natural sciencesDecompression sickness03 medical and health sciencesmedicineRespiratory functionRespiratory systemTidal volumeLung functionLungmedicin och allergiNature and Landscape ConservationHyperbaric TreatmentbiologyEcological Modelinglung functionDiving physiology; decompression sickness; lung function; comparative physiologyrespiratory systembiology.organism_classificationmedicine.diseaseDiving physiologyTreatment efficacyrespiratory tract diseases030104 developmental biologySea turtleAnesthesiaResearch Article
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