Search results for "DISEASE"

Tryptophan Metabolic Pathways and Brain Serotonergic Activity: A Comparative Review

2019

The essential amino acid L-tryptophan (Trp) is the precursor of the monoaminergic neurotransmitter serotonin (5-hydroxytryptamine, 5-HT). Numerous studies have shown that elevated dietary Trp has a suppressive effect on aggressive behavior and post-stress plasma cortisol concentrations in vertebrates, including teleosts. These effects are believed to be mediated by the brain serotonergic system, even though all mechanisms involved are not well understood. The rate of 5-HT biosynthesis is limited by Trp availability, but only in neurons of the hindbrain raphe area predominantly expressing the isoform TPH2 of the enzyme tryptophan hydroxylase (TPH). In the periphery as well as in brain areas …

Biopsychosocial approach to caregiving burden: Why should we care about caregivers’ health?

2018

There are 11 million family caregivers in France and some estimates indicate that there will be 17 million in 2020.Caregiving is a source of chronic stress that requires adaptation and coping strategies.Caregiving may benefit the health of a caregiver with a positive coping style and altruistic goals.However, the caregiver's burden is frequently associated with negative effects in terms of biopsychosocial imbalance and medical conditions, with frequent anxiety and depression.The management of the caregiving burden starts with the recognition of health professionals – caregivers may benefit from consultation-liaison psychiatry and multidisciplinary medico-social strategies, in addition to co…

Advances in the endoscopic management of malignant biliary obstruction

2020

Biliary obstruction is common in pancreatobiliary malignancies and has a negative impact on the patient’s quality of life, postoperative complications, and survival rates. Particularly in the last decade, there has been enormous progress regarding the diagnostic and therapeutic options in patients with malignant biliary obstruction. Endoscopy has given a new insight in this direction and novel techniques have been developed for the better characterization and treatment of malignant strictures. We herein summarize the available data on the different endoscopic techniques, and clarify their role in the diagnosis and treatment of malignant biliary obstructive disease. Finally, we propose an al…

Editorial: Neurobehavioural Mechanisms of Resilience and Vulnerability in Addictive Disorders

2021

I Cannot Read Your Eye Expression: Suicide Attempters Have Difficulties in Interpreting Complex Social Emotions

2020

International audience; Background: The ability to differentiate emotions in social contexts is important for dealing with challenging social situations. Suicide attempters show some difficulties in emotion recognition that may result in hypersensitivity to social stress. However, other studies on the recognition of social complex emotions found that suicide attempters have similar performances as depressed non-attempters. Objectives: To investigate differences in social emotion recognition in patients with current Major Depressive Episode (MDE) with and without history of suicide attempt. Methods: Two hundred and ten patients with MDE were recruited among whom 115 had lifetime history of s…

Analysis of suicide attempts among children hospitalised in the Department of Paediatrics in Zabrze in 2010–2016

2018

Introduction: Despite the current decline in the number of suicides, they are the second most common cause of death among children and adolescents. At the end of the 20th century, suicides represented about 10% of all causes of death of people up to 18 years old, but currently they reach up to 20%. Over the years, the number of suicide attempts (SA) has also increased. Aim of the study: The aim of the study was to analyse the cases of hospitalisation of children in the Department of Paediatrics of the Independent Public Clinical Hospital No. 1 in Zabrze (DP IPCH1) due to a suicide attempt. Material and methods: Medical records of 87 patients hospitalised due to SA in the years 2010–2016 in …

Comparative transcriptomics of albino and warningly‐coloured caterpillars

2021

Abstract Coloration is perhaps one of the most prominent adaptations for survival and reproduction of many taxa. Coloration is of particular importance for aposematic species, which rely on their coloring and patterning acting as a warning signal to deter predators. Most research has focused on the evolution of warning coloration by natural selection. However, little information is available for color mutants of aposematic species, particularly at the genomic level. Here, I compare the transcriptomes of albino mutant caterpillars of the aposematic wood tiger moth (Arctia plantaginis) to those of their full sibs having their distinctive orange‐black warning coloration. The results showed >29…

The Effects of Combined Same Session Aerobic and Resistance Training on Physical Performance in Coronary Artery Disease Patients : Protocol Comparison

2021

Aerobic training is included to cardiac rehabilitation programs together with resistance training. The effects of combined aerobic and resistance training performed in a same session with different protocols on peak aerobic capacity (VO2peak) and maximal dynamic strength (1RM: one repetition maximum) are not well known. We compared the effectiveness of two different combined aerobic and resistance training programs for 12 weeks performed three times in a week in stable Coronary Artery Disease (CAD) patients (n=30) who had previously performed aerobic training only. The patients were randomized to High Volume- Low Intensity Group (HLG) or Low Volume-High Intensity Group (LHG). Both groups pe…

Antibacterial Activity of Positively and Negatively Charged Hematite (α-Fe2O3) Nanoparticles to Escherichia coli, Staphylococcus aureus and Vibrio fi…

2021

This research and work has been supported by the European Regional Development Fund within the Activity 1.1.1.2 “Post-doctoral Research Aid” of the Specific Aid Objective 1.1.1 (i.e., “to increase the research and innovative capacity of scientific institutions of Latvia and the ability to attract external financing, investing in human resources and infrastructure”) of the Operational Programme “Growth and Employment” (No. 1.1.1.2/VIAA/2/18/331).

Additional file 1 of Understanding developmental language disorder - the Helsinki longitudinal SLI study (HelSLI): a study protocol

2018

Appendix 1 Neuropsychological assessment battery. List of neuropsychological assessments used in the study. (DOCX 81 kb)