Search results for "DLS"
showing 10 items of 22 documents
Amyloid Fibrils Formation in Concanavalin A studied by Dynamic Light Scattering and Fluorescence techniques
2007
AMYLOID AGGREGATION IN CONCANAVALIN A AT HIGH PH STUDIED BY LIGHT SCATTERING, FLUORESCENCE AND CIRCULAR DICHROISM SPECTROSCOPY
2008
Small, dense LDL: An update
2017
Purpose of review In this review, we summarize the latest findings on small, dense LDL (sdLDL) atherogenic particles, including their associations with other biomarkers. Recent findings Increased sdLDL levels have been reported not only in different metabolic disorders such as diabetes, obesity and metabolic syndrome, but also in patients with rheumatoid and psoriatic arthritis as well as hypothyroidism. A wide range of lipid-lowering, as well as other drug classes, including novel antidiabetic agents and nutraceuticals, exert favourable effects on these atherogenic particles. The 'gold standard' methodology for the assessment of sdLDL has not been established yet. However, the association …
Aqueous block copolymer-surfactant mixtures and their ability in solubilizing chlorinated organic compounds. A thermodynamic and SANS study.
2006
Within the topic of surfactant enhanced solubilization of additives sparingly soluble in water, volumetric, solubility, conductivity, and small-angle neutron scattering (SANS) experiments on mixtures composed of alpha,omega-dichloroalkane, surfactant, copolymer, and water were carried out at 298 K. The triblock copolymers (ethylene oxide)132(propylene oxide)50(ethylene oxide)132 (F108) and (ethylene oxide)76(propylene oxide)29(ethylene oxide)76 (F68) were chosen to investigate the role of the molecular weight keeping constant the hydrophilic/hydrophobic ratio. The selected surfactants are sodium decanoate (NaDec) and decyltrimethylammonium bromide (DeTAB) with comparable hydrophobicity and …
Quantitative analysis of the impact of a human pathogenic mutation on the CCT5 chaperonin subunit using a proxy archaeal ortholog
2017
The human chaperonin complex is a ~ 1 MDa nanomachine composed of two octameric rings formed from eight similar but non-identical subunits called CCT. Here, we are elucidating the mechanism of a heritable CCT5 subunit mutation that causes profound neuropathy in humans. In previous work, we introduced an equivalent mutation in an archaeal chaperonin that assembles into two octameric rings like in humans but in which all subunits are identical. We reported that the hexadecamer formed by the mutant subunit is unstable with impaired chaperoning functions. This study quantifies the loss of structural stability in the hexadecamer due to the pathogenic mutation, using differential scanning calorim…
An Advanced Sensor for Particles in Gases Using Dynamic Light Scattering in Air as Solvent
2021
Dynamic Light Scattering is a technique currently used to assess the particle size and size distribution by processing the scattered light intensity. Typically, the particles to be investigated are suspended in a liquid solvent. An analysis of the particular conditions required to perform a light scattering experiment on particles in air is presented in detail, together with a simple experimental setup and the data processing procedure. The results reveal that such an experiment is possible and using the setup and the procedure, both simplified to extreme, enables the design of an advanced sensor for particles and fumes that can output the average size of the particles in air.
Low-density lipoproteins generated during an oral fat load in mild hypertriglyceridemic and healthy subjects are smaller, denser, and have an increas…
2005
Triglyceride-rich lipoproteins generated during the postprandial phase are atherogenic. Large very low-density lipoproteins (LDLs) or chylomicrons (CMs) are not as atherogenic as their remnants (Rem). Small and dense LDLs are associated with cardiovascular disease. Low-density lipoprotein size is partly under genetic control and is considered as a relatively stable LDL feature. In this article, we present data on retinyl palmitate kinetics correlated with the modification of LDL features in terms of size, density, and in vitro receptor binding affinity after an oral fat load. Six nondiabetic, hypertriglyceridemic (HTG) patients and 6 healthy controls were examined. Low-density lipoprotein s…
Profiling Suspensions in Natural Water by a Simplified Dynamic Light Scattering Procedure and Sedimentation
2015
Abstract A coherent light scattering experiment was carried out. The samples were aqueous natural water suspensions picked from the same river. While sedimentation occurred in the samples, they were subjected to a dynamic light scattering (DLS) experiment and the time series was recorded at certain time intervals. For each recording, a program written for this purpose, performing at least square minimisation, computed the average diameter of the particles in suspension. The variation of the average diameter in time indicates the dominant type of suspensions in water.
Mass Action Model Applied to the Thermodynamic Properties of Transfer of Nonionic Copolymers from Water to the Aqueous Surfactant Solutions
2003
A thermodynamic model which enables the properties of aqueous copolymer/surfactant mixtures to be fit quantitatively was proposed. Namely, a relationship between the properties of transfer of the unassociated copolymer from water to the aqueous surfactant solutions (DeltaY(t)) and the surfactant concentration was derived. The model was based on the idea that AY, can be expressed in terms of the following contributions: (1) interaction between monomers of copolymer and surfactant, (2) displacement of the monomer-micelle equilibrium induced by the copolymer, (3) formation of the surfactant-copolymer aggregation complex, and (4) formation of the mixed micelles. Such a model was applied to most…
Using Dynamic Light Scattering for Monitoring the Size of the Suspended Particles in Wastewater
2019
Abstract A coherent light scattering experiment on wastewater samples extracted from several stages of water processing within a wastewater processing plant was carried out. The samples were allowed to sediment while they were the subject of a Dynamic Light Scattering (DLS) measurement. The recorded time series were processed using an Artificial Neural Network based DLS procedure to produce the average diameter of the particles in suspension. The method, using a single physical procedure for monitoring the variation of the average diameter in time, indicates the dominant type of suspensions in water.