Search results for "DNA nanotechnology"
showing 3 items of 23 documents
DNA Nanotechnology for Bioanalysis
2017
This book is intended for non-specialists and students, presenting a unique introduction to the field of DNA nanotechnology. The primary focus is on the extraordinary advantages of specificity and sensitivity obtained by integrating DNA nanostructures in bioanalytical devices. DNA Nanotechnology for Bioanalysis provides a concise and rigorous description for the fabrication of various types of functional nanostructures by optimized software-aided high-yield synthesis. Following this is the explanation of methods to decorate these nanostructures with molecules such as proteins, metal nanoparticles or bioorganic moieties covalently bonded onto DNA via self-assemblage processes. Also provided …
Reconfigurable DNA Origami Nanocapsule for pH-Controlled Encapsulation and Display of Cargo
2019
DNA nanotechnology provides a toolbox for creating custom and precise nanostructures with nanometer-level accuracy. These nano-objects are often static by nature and serve as versatile templates for assembling various molecular components in a user-defined way. In addition to the static structures, the intrinsic programmability of DNA nanostructures allows the design of dynamic devices that can perform predefined tasks when triggered with external stimuli, such as drug delivery vehicles whose cargo display or release can be triggered with a specified physical or chemical cue in the biological environment. Here, we present a DNA origami nanocapsule that can be loaded with cargo and reversibl…
Fabrication of DNA origami lattice on silicon surface for DNA-assisted lithography
2022
Metamaterials obtain new properties from having metallized nanoscale features that are often arranged in repeating patterns. In particular, there is a need to create metasurfaces with a negative refractive index. As nanoscale fabrication using conventional top-down methods can be both difficult and time-consuming, bottom-up techniques have gained growing interest. Especially, the DNA origami method can be utilized to assemble lattices with nanoscale features on 2D surfaces, which can then be metallized using DNA-assisted lithography (DALI). This thesis provides a full study of the DNA origami fishnet lattice assembly kinetics and optimization of lattice order on a silicon surface using liqu…