Search results for "DNA"
showing 3 items of 6803 documents
Conservation of the positions of metazoan introns from sponges to humans
2002
Abstract Sponges (phylum Porifera) are the phylogenetic oldest Metazoa still extant. They can be considered as reference animals (Urmetazoa) for the understanding of the evolutionary processes resulting in the creation of Metazoa in general and also for the metazoan gene organization in particular. In the marine sponge Suberites domuncula , genes encoding p38 and JNK kinases contain nine and twelve introns, respectively. Eight introns in both genes share the same positions and the identical phases. One p38 intron slipped for six bases and the JNK gene has three more introns. However, the sequences of the introns are not conserved and the introns in JNK gene are generally much longer. Intron…
Emergence and Disappearance of an Immune Molecule, an Antimicrobial Lectin, in Basal Metazoa
2003
Sponges (phylum Porifera) represent the evolutionarily oldest metazoans that comprise already a complex immune system and are related to the crown taxa of the protostomians and the deuterostomians. Here, we demonstrate the existence of a tachylectin-related protein in the demosponge Suberites domuncula, termed Suberites lectin. The MAPK pathway was activated in response to lipopolysaccharide treatment of the three-dimensional cell aggregates, the primmorphs; this process was abolished by the monosaccharide D-GlcNAc. The cDNA encoding the S. domuncula lectin was identified and cloned; it comprises 238 amino acids (26 kDa) in the open reading frame. The deduced protein has one potential trans…
Itsejärjestäytyvä DNA-kultananopartikkeli-rakenne yhden elektronin transistorina
2012
Tässä tutkielmassa selvitettiin kultananopartikkelien ja itsejärjestäytyvän DNA-järjestelmän soveltuvuutta nanoteknologian komponenttina. Työssä yhdistetään funktionalisoituja kultapartikkeleita jo valmiiksi tutkittuun itsejärjestäytyvään DNA-rakenteeseen työnimeltään BAB. Se muodostuu kolmen TX-tiilen ketjusta, johon suunnittelin kandidaatin tutkinnossani kiinnityskohdat kultapartikkeleille. Yhdistämällä kultapartikkelit ja BAB-rakenne saadaan muodostettua kolmen partikkelin ketju, ja tällä rakenteella pyritään muodostamaan yhden elektronin transistori: Toiminta yhden elektronin transistorina pyrittiin havainnoimaan Coulombin saarron avulla mittaamalla differentiaalista konduktanssia sekä …