Search results for "DOAC"

showing 9 items of 29 documents

CCDC 931326: Experimental Crystal Structure Determination

2013

Related Article: Dawid Siodłak, Maciej Bujak, Monika Staś|2013|J.Mol.Struct.|1047|229|doi:10.1016/j.molstruc.2013.04.078

Space GroupCrystallographyCrystal SystemMethyl 2-acetamidoacrylateCrystal StructureCell ParametersExperimental 3D Coordinates
researchProduct

CCDC 864559: Experimental Crystal Structure Determination

2012

Related Article: J.Ferrando-Soria, T.Grancha, J.Pasan, C.Ruiz-Perez, L.Canadillas-Delgado, Y.Journaux, M.Julve, J.Cano, F.Lloret, E.Pardo|2012|Inorg.Chem.|51|7019|doi:10.1021/ic300953n

Space GroupCrystallographycatena-[bis(mu~5~-22'-(13-Phenylenedinitrilo)bis(oxidoacetato))-bis(mu~4~-22'-(13-phenylenedinitrilo)bis(oxidoacetato))-nona-aqua-tetra-copper(ii)-tetra-manganese(ii) tetradecahydrate]Crystal SystemCrystal StructureCell ParametersExperimental 3D Coordinates
researchProduct

New Gold(I) Organometallic Compounds with Biological Activity in Cancer Cells

2014

N-Heterocyclic carbene gold(I) complexes bearing a fluorescent coumarin ligand were synthesized and characterized by various techniques. The compounds were examined for their antiproliferative effects in normal and tumor cells in vitro; they demonstrated moderate activity and a certain degree of selectivity. The compounds were also shown to efficiently inhibit the selenoenzyme thioredoxin reductase (TrxR), whereas they were poorly effective towards the glutathione reductase (GR) and glutathione peroxidase enzymes. Notably, {3-[(7-methoxy-2-oxo-2H-chromen-4-yl) methyl]-1-methylimidazol-2-ylidene}(tetra-O-acetyl-1-thio-beta-D-glucopyranosido) gold(I) (3) showed a pronounced inhibition of TrxR…

Thioredoxin reductaseGlutathione reductaseMECHANISMSInorganic Chemistrychemistry.chemical_compoundCoumarinsCHEMISTRYTARGETSN-HETEROCYCLIC CARBENESCancerchemistry.chemical_classificationSelenocysteineGlutathione peroxidaseGold; carbenes; coumarins; enzyme; CancerBiological activityLigand (biochemistry)EnzymesenzymechemistryBiochemistryCancer cellIodoacetamideCarbenesANTICANCER AGENTSCOMPLEXESGold
researchProduct

La diversité des communautés végétales des forêts alluviales de l’Allier est-elle affectée par l’invasion de l’Érable négundo, du Robinier faux-acaci…

2012

Identifiant ProdInra 270418 SPE EcolDur CT3; Master; L’objectif de notre étude a été d’analyser les effets de l’invasion de 3 espèces végétales (Érable négundo, Robinier faux-acacia, Renouée de Bohême) sur la diversité spécifique et fonctionnelle ainsi que sur la structure et la composition spécifique des communautés végétales des forêts alluviales de l’Allier. Des relevés de végétation ont été réalisés dans des paires de quadrats contiguës, envahis et non envahis par les 3 espèces invasives étudiées et dans 3 habitats envahis des forêts alluviales de l’Allier (Saulaie-peupleraie de niveau topographique haut et bas et Chênaie pédonculée-ormaie). Complémentairement à cette approche, un gradi…

[SDV] Life Sciences [q-bio][SDE] Environmental Sciences[SDV]Life Sciences [q-bio][SDE]Environmental Sciencesplante invasive[SDV.BV]Life Sciences [q-bio]/Vegetal Biologyforêt alluvialeacer negundodiversité spécifique et fonctionnelle[SDV.BV] Life Sciences [q-bio]/Vegetal Biologyreynoutria x bohemicarobinia pseudoacacia
researchProduct

CCDC 1414395: Experimental Crystal Structure Determination

2016

Related Article: Marta Mon, Alejandro Pascual-Álvarez, Thais Grancha, Joan Cano, Jesús Ferrando-Soria, Francesc Lloret, Jorge Gascon, Jorge Pasán, Donatella Armentano, Emilio Pardo|2016|Chem.-Eur.J.|22|539|doi:10.1002/chem.201504176

catena-[tri-sodium (5101520-tetraphenylporphryinato)-manganese(iii) bis(tris(mu-22'-((246-trimethyl-13-phenylene)diazanylylidene)bis(oxidoacetato))-tetra-aqua-tri-copper(ii)-di-manganese(ii)) unknown solvate pentatriacontahydrate]Space GroupCrystallographyCrystal SystemCrystal StructureCell ParametersExperimental 3D Coordinates
researchProduct

Intra-Articular Injection of Fructus Ligustri Lucidi Extract Attenuates Pain Behavior and Cartilage Degeneration in Mono-Iodoacetate Induced Osteoart…

2018

Fructus Ligustri Lucidi (FLL) has been widely used as a traditional Chinese medicine (TCM) for treating soreness and weakness of waist and knees. It has potential for treating OA owing to its kidney-tonifying activity with bone-strengthening effects, but there is so far no report of its anti-OA effect. This study established a rat OA model by intra-articular (IA) injection of mono-iodoacetate (1.5 mg) and weekly treated by IA administration of FLL at 100 μg/mL for 4 weeks. Thermal withdrawal latency, mechanical withdrawal threshold, and spontaneous activity were tested for evaluation of pain behavior, and histopathological (HE, SO, and ABH staining) and immunohistochemical (Col2, Col10, and…

medicine.medical_specialtyChondrocyte hypertrophyintra-articularChondrocyteMuscle hypertrophymono-iodoacetateExtracellular matrix03 medical and health sciences0302 clinical medicineInternal medicinemedicinePharmacology (medical)MTT assayAggrecanFructus Ligustri LucidiOriginal Research030203 arthritis & rheumatologyPharmacologyChemistryCartilagelcsh:RM1-950medicine.anatomical_structureEndocrinologylcsh:Therapeutics. Pharmacology030220 oncology & carcinogenesisJoint painchondrocytemedicine.symptomhypertrophyFrontiers in Pharmacology
researchProduct

A multicenter real‐life study on anticoagulant treatment with direct oral anticoagulants in patients with P h‐negative myeloproliferative neoplasms

2020

NA

medicine.medical_specialtyDOACbusiness.industrymyeloproliferative neoplasmvenous thromboembolismMEDLINEdirect oral anticoagulantAtrial fibrillationHematologymedicine.diseasePhiladelphia chromosomeClinical trialText miningAnticoagulant therapyInternal medicineMedicineLife studybusinessMyeloproliferative neoplasmatrial fibrillation.American Journal of Hematology
researchProduct

The changing landscape of thromboprophylaxis for atrial fibrillation: insights from the ISPAF-2 survey

2018

Atrial fibrillation is the most common sustained cardiac dysrhythmia. It represents a major public health problem due to increased mortality risk, reduced quality of life, and increased health costs [1, 2]. The prevalence of nonvalvular atrial fibrillation (AF) continues to increase worldwide, largely affecting the elderly, but also occurring in younger patients as a result of structural heart disease, autonomic imbalance, genetic abnormality, or previous cardiac surgery [3]. The rise in prevalence of AF is largely due to the increasing age of the population. About 1–2% of the total population is affected by AF, but the prevalence of this condition rises to ≈ 10% in individuals aged > 75…

medicine.medical_specialtySettore MED/09 - Medicina Internabusiness.industryMEDLINEAtrial fibrillaztion - Anticoagulants - NOACs - DOACsAnticoagulantsAtrial fibrillation030204 cardiovascular system & hematologymedicine.diseaseStroke03 medical and health sciences0302 clinical medicineItalySurveys and QuestionnairesAtrial FibrillationEmergency MedicineInternal MedicinemedicineHumans030212 general & internal medicineIntensive care medicinebusinessStroke
researchProduct

Effects of retinotoxic drugs on rats heterozygotic for recessive retinitis pigmentosa

1971

medicine.medical_specialtybusiness.industryIodoacetatesRats Inbred Strainsmedicine.diseaseRetinaSensory SystemsRatsFluoridesOphthalmologyEndocrinologyInternal medicineInjections IntravenousRetinitis pigmentosaElectroretinographymedicineAnimalsCholinesterasesbusinessRetinitis PigmentosaVision Research
researchProduct