Search results for "DOMAIN"
showing 10 items of 2485 documents
The Proterozoic Franceville Basin (S.E. Gabon): an example of interaction between marine sedimentation and extensional faulting.
2006
30 pages; International audience
Quelques questions concernant la contribution de MO fossile dans le cycle supergène
2003
Bien qu'observée depuis plus d'un siècle dans les cours d'eau, les sédiments et plus récemment dans les sols (un exemple parmi d'autres : [1]), la contribution potentielle de carbone organique (Corg) que nous qualifierons de géologique et libéré par l'altération des formations géologiques n'a que rarement été, excepté [2], prise en compte dans les bilans globaux concernant le cycle supergène (références dans [3]). Pourtant les formations géologiques classiquement reconnues comme contenant du Corg. représentent plus de 50% des surfaces continentales. Une estimation de ce que nous pouvons appeler une production organique liée à l'érosion chimique des roches carbonatées (carbonates, shales) a …
Dynamique sédimentaire des dépôts post-rift du bassin intérieur du Gabon.
2006
14 pages; International audience
Rheological properties of thermal gels of pea and egg white protein mixtures
2021
International audience
Terahertz Biomedical Imaging: From Multivariate Analysis and Detection to Material Parameter Extraction
2017
Terahertz imaging is an interesting route for biomedical analysis. In particular, cancer imaging is a subject of study for different teams [1,2]. A work is done in Bordeaux in partnership with a hospital to do terahertz analysis of breast tissue. This work is done in reflection with time domain imaging setup with fresh samples. The aim is to accurately assess tumor margins and which could in the future allow a quick validation of the precision of the surgical procedure and know if new surgery should be performed. We have presented in a previous paper [3] the use of automatic methods of image generation with different parameters [4] in order to explore the different contrasts that exist in t…
Rôle de la Dynamique Membranaire dans la Mise en Place des Mécanismes de Défense chez le Tabac
2011
Cryptogein, a protein secreted by the oomycete Phytophthora cryptogea, induces defense mechanisms in tobacco. Several proteins involved in the associated signaling pathway were identified and localized on the plasma membrane (PM). A fraction resistant to solubilization by detergent named DIMs for Detergent Insoluble Membranes, enriched in sterols an sphigolipids had been isolated from tobacco PM. It was proved to contain proteins previously identified as actors of the signaling cascade triggered by cryptogein. In animal cells, the dynamic association of proteins to sterol and sphingolipid rich microdomains under the influence of a biological stimulus plays an essential role in the regulatio…
Liquid ordered domains of tobacco cell plasma membrane : in vivo visualization, spatial distribution and modulation upon elicitation
2012
SPE IPM; International audience; The ability of lipids in complex mixtures to form liquid-ordered, sterol-rich phases, together with the association of specific proteins with sterol-enriched biochemical fractions extracted from biological membranes, gave raise to the "lipid rafts" hypothesis. This suggests the presence within biological membranes of small-sized, ordered domains, of particular lipid and protein composition, which could serve as signal transduction platforms, particularly during plant-microorganisms interactions. However, the precise organization of living cell plasma membrane is still poorly described and the spatial distribution of segregating liquid-disordered and liquid-o…
Plasma membrane microdomains in plants: for which physiological roles?
2007
International audience; A large body of evidence supports the existence, in membrane from animal and yeast cells, of functional microdomains playing important roles in protein sorting, signal transduction, or infection by pathogens (1). We demonstrated the presence, in plants, of detergent resistant fractions isolated from plasma membrane, with a lipidic composition similar to animal microdomains (2). Electrophoresis experiments indicated that these fractions were able to recruit a specific set of plasma membrane proteins and exclude others. We used mass spectrometry to give an extensive description of a tobacco plasma membrane microdomains. This led to the identification of 145 proteins wh…
Interactions in the network of Usher syndrome type 1 proteins
2004
International audience; Defects in myosin VIIa, harmonin (a PDZ domain protein), cadherin 23, protocadherin 15 and sans (a putative scaffolding protein), underlie five forms of Usher syndrome type I (USH1). Mouse mutants for all these proteins exhibit disorganization of their hair bundle, which is the mechanotransduction receptive structure of the inner ear sensory cells, the cochlear and vestibular hair cells. We have previously demonstrated that harmonin interacts with cadherin 23 and myosin VIIa. Here we address the extent of interactions between the five known USH1 proteins. We establish the previously suggested sans-harmonin interaction and find that sans also binds to myosin VIIa. We …
Rbt1 Protein Domains Analysis in Candida albicans Brings Insights into Hyphal Surface Modifications and Rbt1 Potential Role during Adhesion and Biofi…
2013
Cell wall proteins are central to the virulence of Candida albicans. Hwp1, Hwp2 and Rbt1 form a family of hypha-associated cell surface proteins. Hwp1 and Hwp2 have been involved in adhesion and other virulence traits but Rbt1 is still poorly characterized. To assess the role of Rbt1 in the interaction of C. albicans with biotic and abiotic surfaces independently of its morphological state, heterologous expression and promoter swap strategies were applied. The N-terminal domain with features typical of the Flo11 superfamily was found to be essential for adhesiveness to polystyrene through an increase in cell surface hydrophobicity. A 42 amino acid-long domain localized in the central part o…