Search results for "DOMAIN"
showing 10 items of 2485 documents
Numerical Algorithms Based on Characteristic Domain Decomposition for Obstacle Problems
1997
A new numerical solution algorithm for obstacle problems is proposed, where the characteristic domain decomposition into active and inactive subdomains separated by the free boundary is approximated by a Schwarz method. Such an approach gives an opportunity to apply fast linear system solvers to genuinely non-linear obstacle problems. Other solution algorithms, like projected relaxation methods and active set strategies, are compared to the new solution algorithm. Numerical experiments related to the elastoplastic torsion problem are included showing the efficiency of the new approach.
The Calderón problem for the fractional Schrödinger equation
2020
We show global uniqueness in an inverse problem for the fractional Schr\"odinger equation: an unknown potential in a bounded domain is uniquely determined by exterior measurements of solutions. We also show global uniqueness in the partial data problem where the measurements are taken in arbitrary open, possibly disjoint, subsets of the exterior. The results apply in any dimension $\geq 2$ and are based on a strong approximation property of the fractional equation that extends earlier work. This special feature of the nonlocal equation renders the analysis of related inverse problems radically different from the traditional Calder\'on problem.
Dificultades de aprendizaje y cambio conceptual, procedimental y axiológico (II): nuevas perspectivas
2009
En este trabajo veremos como las ciencias cognitivas, las neurociencias, los estudios CTS, la educacion cientifica no formal, etc., ofrecen nuevas posibilidades de avance en el campo del aprendizaje de conceptos, procedimientos y actitudes, y tambien veremos otras perspectivas que amplian el dominio usual de la didactica de las ciencias. Por ultimo, se muestra como los modelos de ensenanza deben tener en cuenta estas dimensiones del aprendizaje de las ciencias, para contribuir a la solucion de los nuevos problemas que se plantean sobre la educacion cientifica.Palabras clave: ciencias cognitivas; neurociencias; estudios CTSA; ensenanza, aprendizaje.Learning difficulties and conceptual, metho…
Medical Data Mining for Heart Diseases and the Future of Sequential Mining in Medical Field
2018
Data Mining in general is the act of extracting interesting patterns and discovering non-trivial knowledge from a large amount of data. Medical data mining can be used to understand the events happened in the past, i.e. studying a patients vital signs to understand his complications and discover why he has died, or to predict the future by analyzing the events that had happened. In this chapter we are presenting an overview on studies that use data mining to predict heart failure and heart diseases classes. We will also focus on one of the trendiest data-mining field, namely the Sequential Mining, which is a very promising paradigm. Due to its important results in many fields, this chapter …
Computational approach to design of aptamers to the receptor binding domain of SARS-CoV-2
2021
The aim of the research. In this work, in silico selection of DNA-aptamers to the receptor-binding domain (RBD) of the SARS-CoV-2 spike protein was performed using molecular modeling methods. Material and methods. A new computational approach to aptamer in silico selection is based on a cycle of simulations, including the stages of molecular modeling, molecular docking, molecular dynamic simulations, and quantum chemical calculations. To verify the obtained calculated results flow cytometry, fluorescence polarization, and small-angle X-ray scattering methods were applied. Results. An initial library consisted of 256 16-mer oligonucleotides was modeled. Based on molecular docking results, th…
De la dualité de l'arbitrage commercial et de l'arbitrage administratif
2010
International audience; (T. confl., 17 mai 2010, n° 3754, Institut national de la santé et de la recherche médicale c/ Fondation Letten F. Saugstad, Lebon ; AJDA 2010. 1047 ; ibid. 1564, étude P. Cassia ; D. 2010. 1359, obs. X. Delpech ; ibid. 2323, obs. L. d'Avout et S. Bollée)
A Generic Architectural Model Approach for Efficient Utilization of Patterns
2015
A software pattern describes the core of the solution to a problem that tends to (re-)occur in a particular environment. Such patterns are commonly used as a means to facilitate the creation of an architectural design satisfying the desired quality goals. In this chapter, the practical challenges of efficient usage of patterns in domain-specific software development are presented. The specific domain considered here is the mobile domain, for which is given a sample collection of potentially useful patterns. After that, a novel generic architectural model approach for organizing patterns is presented. In this approach, the identification of relevant patterns is considered as the process of r…
orthoFind Facilitates the Discovery of Homologous and Orthologous Proteins
2015
Finding homologous and orthologous protein sequences is often the first step in evolutionary studies, annotation projects, and experiments of functional complementation. Despite all currently available computational tools, there is a requirement for easy-to-use tools that provide functional information. Here, a new web application called orthoFind is presented, which allows a quick search for homologous and orthologous proteins given one or more query sequences, allowing a recurrent and exhaustive search against reference proteomes, and being able to include user databases. It addresses the protein multidomain problem, searching for homologs with the same domain architecture, and gives a si…
Agent-Oriented Captology for Anthropocentric Systems
2001
Abstract Considering that anthropo centric systems are an adequate domain for captological approaches, and that interface agents are most natural interactants for the humans involved, the paper presents a broad-spectrum generic architectural framework to support developing flexible interfaces for industrial applications, based on synergetic correlation between persuasive technologies and polymorphic agents. The design space for agent-oriented captology is defined and several of its main dimensions are elaborated upon. The main mechanisms used are dynamic priorities, "flexible cloning" and fuzzy temporal windows. Some agent-oriented test-bench applications instantiating the generic architect…
Enquête sur les archives ouvertes françaises menée par Couperin en 2019 : résultats et analyses
2020
French Higher Education Institutions (HEIs) are, for 89% of the respondents to the survey, now having their own open repository, or declaring to be in the implementation phase (compared to 82% in 2017 and only 62% in 2014). It can therefore be considered that almost all HEIs now offer a green open access repository or signalling solution to their researchers. The « still in progress » or suspended projects are rather related to the current recomposition of the Higher Education landscape. The most obvious obstacles to the latest implementations remain both the low involvement of researchers in the project and the human resources allocated. There is a slight but real increase in the rate of i…