Search results for "DOP"

showing 10 items of 4870 documents

The incidence of psychotic disorders among migrants and minority ethnic groups in Europe: findings from the multinational EU-GEI study

2022

AbstractBackgroundIn Europe, the incidence of psychotic disorder is high in certain migrant and minority ethnic groups (hence: ‘minorities’). However, it is unknown how the incidence pattern for these groups varies within this continent. Our objective was to compare, across sites in France, Italy, Spain, the UK and the Netherlands, the incidence rates for minorities and the incidence rate ratios (IRRs, minorities v. the local reference population).MethodsThe European Network of National Schizophrenia Networks Studying Gene–Environment Interactions (EU-GEI) study was conducted between 2010 and 2015. We analyzed data on incident cases of non-organic psychosis (International Classification of …

medicine.medical_specialtyDopamineRegion of originEthnic groupmigrationpsychosistress03 medical and health sciencesRace (biology)0302 clinical medicineEpidemiologymedicineHumanspsychosis10. No inequalityraceMinority GroupsApplied PsychologyTransients and MigrantsHigh rateIncidenceIncidence (epidemiology)Social environmentPREVALENCE030227 psychiatry3. Good healthEuropeschizophreniaPsychiatry and Mental healthGeographyPsychotic DisordersMultinational corporation1ST-CONTACT INCIDENCEethnicityepidemiology030217 neurology & neurosurgerySOCIAL DEFEAT HYPOTHESISDemographyPsychological Medicine
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Left ventricular non-compaction cardiomyopathy in children: Is segmental fibrosis the cause of tissue Doppler alterations and of EF reduction?

2009

Noncompaction of the ventricular myocardium (LVNC) is a rare congenital cardiomyopathy resulting from an arrest in normal endomyocardial embryogenesis. In 2002 Jenni et al. [Jenni R, Wyss CA, Oechslin EN, Kaufmann PA. Isolated ventricular noncompaction is associated with coronary microcirculatory dysfunction. J Am Coll Cardiol 2002; 39:450-454.] reported a microvascular dysfunction in 12 patients affected by non compaction: areas of restricted myocardial perfusion have been documented by scintigraphy, suggesting a reduction of Coronary flow reserve. McMahon et al reported in a recent article a reduction of TD velocities in children with noncompaction of the left ventricle, compared with nor…

medicine.medical_specialtyEjection fractionmedicine.diagnostic_testbusiness.industryHeart VentriclesCardiomyopathyCoronary flow reserveStroke VolumeScintigraphymedicine.diseaseFibrosisEchocardiography DopplerTransplantationmedicine.anatomical_structureLeft ventricular non-compactionVentricleFibrosisInternal medicineCardiologymedicineHumansCardiology and Cardiovascular MedicinebusinessCardiomyopathiesPerfusion
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Effects of Different Opioid Receptor Antagonists on the Electrically-Evoked Release of Endogenous Dopamine from the Isolated Neural Lobe of the Rat P…

2009

Abstract Isolated neural lobes of the rat pituitary gland were incubated in Krebs-HEPES solution which contained the dopamine uptake inhibitor GBR 12921 and in some experiments additionally pargyline. The release of endogenous dopamine evoked by electrical stimulation of the pituitary stalk was determined by high-performance liquid chromatography with electrochemical detection. (+/-)- Naloxone increased the evoked dopamine release maximally by 440% (EC(50) 209 nM). The (+)-enantiomer of naloxone (up to 10 muM) did not affect the release of dopamine. The preferential kappa-opioid receptor antagonist MR 2266 increased the evoked dopamine release maximally by 135% (EC(50) 7 nM). MR 2267, the i…

medicine.medical_specialtyEndocrine and Autonomic SystemsChemistrymedicine.drug_classEndocrinology Diabetes and Metabolism(+)-NaloxonePharmacologyCellular and Molecular NeuroscienceEndocrinologyEndocrinologyDopamine receptor D1Dopamine receptorOpioid receptorDopamineInternal medicineDopamine receptor D2medicineEndogenous agonistEndogenous opioidmedicine.drugJournal of neuroendocrinology
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INTERACTION BETWEEN NORADRENALINE AND DOPAMINE IN THE ISOLATED GUINEA-PIGATRIA

1978

medicine.medical_specialtyEndocrinologyChemistryDopamineInternal medicinemedicinemedicine.drug
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Chapter 7: Incidence of Endophthalmitis in Ophthalmic Surgery

2002

medicine.medical_specialtyEndophthalmitisbusiness.industryOphthalmologyIncidence (epidemiology)medicinemedicine.diseasebusinessOphthalmic surgerySurgery
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The Harderian Gland of the Djungarian Hamster (<i>Phodopus sungorus</i>): Light- and Electron-Microscopical Investigations

1993

The Harderian gland of the Djungarian hamster Phodopus sungorus was investigated by light and electron microscopy in adult animals of both sexes, held under either long or short photoperiods. These glands have a tubuloalveolar structure. Epithelial cells were seen as small cylindric cells with a large, round nucleus located basally, many small vacuoles distributed throughout the cytoplasm (type I cells) or as rather broad cells with larger vacuoles (type II cells). The ratio of both cell types differed from 1:1 to 2:1 (type I:type II), regardless of the animal’s sex. In the electron microscope, abundant smooth endoplasmic reticulum of the vesicular type and rod-like or oval-shaped mitochond…

medicine.medical_specialtyExocrine glandHistologybiologyHamsterGlandula exocrinabiology.organism_classificationlaw.inventionPhodopusHarderian glandEndocrinologymedicine.anatomical_structurelawInternal medicinemedicineUltrastructureAnatomyElectron microscopeCells Tissues Organs
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Ambulatory assessment as a means of longitudinal phenotypes characterization in psychiatric disorders

2014

Abstract Ambulatory Assessment (AA) comprises the use of in-field methods to assess individuals’ behavior, physiology, and the experience as they unfold in naturalistic settings. We propose that AA is favorable for the investigation of gene–environment interactions and for the search for endophenotypes, being able to assess the experienced environment and to track basic regulatory processes, such as stress reactivity, affective instability, and reward experience, which are potential common factors that underlie psychiatric disorders. In this article, we (a) first describe briefly the rationale of AA and summarize the key advantages of the approach, (b) highlight within-subject regulatory pr…

medicine.medical_specialtyExperience sampling methodMood DisordersMental DisordersGeneral NeuroscienceMonitoring AmbulatoryGeneral MedicinePhenotype030227 psychiatry03 medical and health sciencesFamily studiesPhenotype0302 clinical medicinePsychotic DisordersEndophenotypemedicineHumansGene-Environment InteractionStress reactivityPsychiatryPsychology030217 neurology & neurosurgeryPsychiatric geneticsClinical psychologyNeuroscience Research
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OC005: Ultrasound bioeffects: Quantification of cellular damage in animal fetal liver after use of Doppler pulse to measure ductus venosus

2008

medicine.medical_specialtyFetusRadiological and Ultrasound TechnologyPulse (signal processing)business.industryUltrasoundMeasure (physics)Obstetrics and GynecologyGeneral Medicinesymbols.namesakeReproductive MedicineInternal medicinemedicinesymbolsCardiologyRadiology Nuclear Medicine and imagingbusinessDoppler effectDuctus venosusUltrasound in Obstetrics and Gynecology
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Endocrinology and physiology of pseudocyesis

2013

This literature review on pseudocyesis or false pregnancy aims to find epidemiological, psychiatric/psychologic, gynecological and endocrine traits associated with this condition in order to propose neuroendocrine/endocrine mechanisms leading to the emergence of pseudocyetic traits. Ten women from 5 selected studies were analyzed after applying stringent criteria to discriminate between cases of true pseudocyesis (pseudocyesis vera) versus delusional, simulated or erroneous pseudocyesis. The analysis of the reviewed studies evidenced that pseudocyesis shares many endocrine traits with both polycystic ovarian syndrome and major depressive disorder, although the endocrine traits are more akin…

medicine.medical_specialtyGalactorrheaPolycystic ovarian syndromeReproductive medicinePhysiologyReviewBiologyMajor depression disorderDiagnosis DifferentialGonadotropin-Releasing HormoneEndocrinologyCatecholaminesInternal medicineHypomenorrheamedicineEndocrine systemHumansNervous System Physiological PhenomenaPseudopregnancyHypothalamus-pituitary-ovarian axisDepressive Disorder MajorObstetrics and Gynecologymedicine.diseaseEndocrinologyReproductive MedicineSympathetic nervous systemMajor depressive disorderAmenorrheaFemalemedicine.symptomFalse pregnancyHormoneDevelopmental BiologyPolycystic Ovary Syndrome
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Progressive Endoplasmic Reticulum Stress Contributes to Hepatocarcinogenesis in Fatty Acyl-CoA Oxidase 1–Deficient Mice

2011

Fatty acyl-coenzyme A oxidase 1 (ACOX1) knockout (ACOX1(-/-)) mice manifest hepatic metabolic derangements that lead to the development of steatohepatitis, hepatocellular regeneration, spontaneous peroxisome proliferation, and hepatocellular carcinomas. Deficiency of ACOX1 results in unmetabolized substrates of this enzyme that function as biological ligands for peroxisome proliferator-activated receptor-α (PPARα) in liver. Here we demonstrate that sustained activation of PPARα in ACOX1(-/-) mouse liver by these ACOX1 substrates results in endoplasmic reticulum (ER) stress. Overexpression of transcriptional regulator p8 and its ER stress-related effectors such as the pseudokinase tribbles h…

medicine.medical_specialtyGenotypePeroxisome proliferator-activated receptorPeroxisome ProliferationMice TransgenicBiologyEndoplasmic ReticulumModels BiologicalPathology and Forensic MedicineMiceInternal medicinemedicineAnimalsHumansAcyl-CoA oxidasePPAR alphaTransgenesDNA Primerschemistry.chemical_classificationLiver cellEndoplasmic reticulumLiver NeoplasmsRegular ArticlePeroxisomemedicine.diseaseNeoplasm ProteinsCell biologyDNA-Binding ProteinsMice Inbred C57BLEndocrinologyGene Expression RegulationLiverchemistryHepatocytesUnfolded protein responseAcyl-CoA OxidaseSteatohepatitisThe American Journal of Pathology
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