Search results for "DOP"

showing 10 items of 4870 documents

Análogos de las benztropinas como agentes terapéuticos para la adicción a la cocaína: Estudios preclínicos en modelos animales de conducta adictiva

2015

La adicción a cocaína es un fenómeno de gran importancia clínica y social. Las consecuencias negativas que produce el abuso de estas sustancias son significativas, incluyendo problemas médicos, psicosociales y laborales para los individuos afectados. Además, su abuso está asociado a tasas incrementadas de crimen y violencia. La dependencia se caracteriza por tasas elevadas de recaída en un patrón cíclico de búsqueda y consumo. Estas recaídas pueden producirse incluso después de períodos prolongados de abstinencia. Dadas estas premisas, uno de los principales objetivos de nuestro trabajo es la identificación de fármacos que puedan atenuar el deseo compulsivo (“craving”) de consumir y reducir…

terapéutica:PSICOLOGÍA::Psicofarmacología [UNESCO]dopaminapsicoestimulantescocaínaAdicciónUNESCO::PSICOLOGÍA::Psicofarmacologíabenzotropina
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Understanding the White-Emitting CaMoO4 Co-Doped Eu3+, Tb3+, and Tm3+ Phosphor through Experiment and Computation

2019

In this article, the synthesis by means of the spray pyrolysis method, of the CaMoO4 and rare-earth cation (RE3+)-doped CaMoO4:xRE3+ (RE3+ = Eu3+, Tb3+, and Tm3+; and x = 1, 2, and 4% mol) compounds, is presented. The as-synthesized samples were characterized using X-ray diffraction, Rietveld refinement, field emission scanning electron microscopy (FE-SEM), Raman spectroscopy, and photoluminescence (PL) spectroscopy. To complement and rationalize the experimental results, first-principles calculations, at the density functional theory level, have been performed to analyze the band structure and density of states. In addition, a theoretical method based on the calculations of surface energie…

terbium compoundsMaterials scienceTm3+lightingAnalytical chemistryfield emission microscopes02 engineering and technology010402 general chemistry01 natural sciencesSpray pyrolysiseuropium compoundsTb3+White-Emitting CaMoO4Physical and Theoretical Chemistrydensity functional theorycalcium compoundscomputation theoryenamelsPhosphor021001 nanoscience & nanotechnologyred phosphorselectronic structureCo-Doped Eu3+0104 chemical sciencesSurfaces Coatings and FilmsElectronic Optical and Magnetic MaterialsESTRUTURA ELETRÔNICAGeneral Energyphotoluminescence spectroscopylight emissionphosphors0210 nano-technologyspray pyrolysisCo dopedscanning electron microscopy
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Termoelektrisko īpašību pētījumi tetratiotetracēna atvasinājumu plānās kārtiņās

2018

Darbā tika izveidotas organisku pusvadītāju - tetratiotetracēna (TTT) atvasinājumu plānas kārtiņas, izmantojot termiskās iztvaicēšanas metodi vakuumā. Izmantotie atvasinājumi ir ar metil, ¬¬metoksi, fenil un izopropil grupu aizvietojumiem 2. un 8. tetratiotetracēna molekulas pozīcijā, dažādās kombinācijās. Tika pētīta plāno kārtiņu morfoloģija, izmantojot ar skenējošā elektronu mikroskopu iegūtos attēlus, kā arī termoelektriskās īpašības, nosakot to elektrisko vadītspēju un Zēbeka koeficientu. Plānās kārtiņas tika pētītas gan tīrā veidā kā arī dopētas ar jodu, iegūstot p-tipa pusvadītāja īpašības. Tika izveidots tetratiotetracēna plāno kārtiņu termoelektriskais ģenerators. Darbā ir veikti t…

termoelektriskais ģeneratorsdopēšanaorganiskie pusvadītājitermoelektriskais efektsFizikatetratiotetracēns
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CCDC 855772: Experimental Crystal Structure Determination

2013

Related Article: Ralf W. Troff,Toni Mäkelä,Filip Topić,Arto Valkonen,Kari Raatikainen,Kari Rissanen|2013|Eur.J.Org.Chem.|2013|1617|doi:10.1002/ejoc.201201512

tetrakis(1-iodopyrrolidine-25-dione) 1357-tetraazatricyclo[3.3.1.137]decane chloroform solvateSpace GroupCrystallographyCrystal SystemCrystal StructureCell ParametersExperimental 3D Coordinates
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Il primo concorso per il Palazzo di Giustizia a Roma del 1884. Ricostruzione critica del progetto di Ernesto Basile

2019

1. Breve descrizione dell’oggetto di studio Il concorso del Palazzo di Giustizia di Roma si svolge in quattro fasi svolte tra il 1884 e il 1887. Il progetto per il primo concorso, del 1884, redatto dall’allora giovanissimo Ernesto Basile (Palermo 1857-1932), rivela una grande perizia progettuale che trasforma il complesso programma funzionale in un austero edificio in stile neofiorentino. I disegni originari dell’opera, non realizzata, conservati presso la Dotazione Basile del Dipartimento di Architettura dell’Università di Palermo, sono stati oggetto di studio propedeutico alle fasi di analisi, interpretazione e ricostruzione congetturale del modello digitale. 2. Stato dell’arte e riferime…

the spatiality of the great vestibule• elaboration of axonometric and perspective view• choice of interpretation criteria in case of project incongruitiethe vaulted arcades.the space of the main courtyard which Basile outlines in a sketch• elaboration of analytical drawings (modular functional compositional volumetric schemes)• modular study and flat vectorization• application of rendering techniques consistent with the available information. 4. Objectives pursued and achieved Conjectural reconstruction achieved the following results: • formulation of analytical documents which show how the planimetric and altimetric articulation are perfectly consistent with the functional program• definition of the level of uncertainty1. Brief description of the object of study The competition of the Palace of Justice in Rome takes place in four phases between 1884 and 1887. The project for the first competition in 1884 drawn up by the then very young Ernesto Basile (Palermo 1857-1932) reveals a great deal of design expertise that transforms the complex functional program into an austere building in neo-florentine style. The original drawings of the building not realized kept in the Basile Endowment of the Department of Architecture of the University of Palermo have been the subject of preliminary study to the phases of analysis interpretation and conceptual reconstruction of the digital model. 2. State of the art and main bibliographical references The conjectural reconstruction on the basis of drawings and archival documents is a well-established and codified practice thanks to various disciplinary contributions at national and international level. See: F. I. Apollonio Classification Schemes for Visualization of Uncertainty in Digital Hypothetical Reconstruction in M. Sander P. Mieke P. Kuroczyński M. Ioannides 3D Research Challenges in Cultural Heritage II Cham (CH) 2016. G. Antista M. Cannella Ricostruire. Architettura - Storia – Rappresentazione Palermo 2015. For studies related to the examinated project see: E. Mauro E. Sessa I disegni della Collezione Basile Roma 2015. E. Sessa Ernesto Basile. Dall'eclettismo Classicista al Modernismo Palermo 2002. 3. Definition of the methodologies adopted in the research Methodological phases: • historical analysi• survey of the original drawings and dimensional verification of the flat scanSettore ICAR/17 - Disegno• construction of perspective views deduced from the original drawings that highlight: the volumetric hierarchy and the function of the bugnate in the scanning of the masonry ma• three-dimensional modeling
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Protein tyrosine nitration and thiol oxidation by peroxynitrite-strategies to prevent these oxidative modifications.

2013

The reaction product of nitric oxide and superoxide, peroxynitrite, is a potent biological oxidant. The most important oxidative protein modifications described for peroxynitrite are cysteine-thiol oxidation and tyrosine nitration. We have previously demonstrated that intrinsic heme-thiolate (P450)-dependent enzymatic catalysis increases the nitration of tyrosine 430 in prostacyclin synthase and results in loss of activity which contributes to endothelial dysfunction. We here report the sensitive peroxynitrite-dependent nitration of an over-expressed and partially purified human prostacyclin synthase (3.3 μM) with an EC50 value of 5 μM. Microsomal thiols in these preparations effectively co…

thiol oxidationprotein tyrosine nitrationlcsh:Chemistrychemistry.chemical_compoundCytochrome P-450 Enzyme SystemSf9 CellsTyrosinelcsh:QH301-705.5Spectroscopychemistry.chemical_classification0303 health sciencesbiologySuperoxide030302 biochemistry & molecular biologyGeneral MedicineComputer Science ApplicationsIntramolecular OxidoreductasesBiochemistryThiolprostacyclin synthasesuperoxideOxidation-ReductionPeroxynitriteOxidative phosphorylationSpodopteraCatalysisArticleperoxynitriteNitric oxideProstacyclin synthaseInorganic Chemistry03 medical and health sciencesnitric oxideddc:570NitrationPeroxynitrous AcidAnimalsHumansSulfhydryl CompoundsPhysical and Theoretical ChemistryMolecular Biology030304 developmental biologyOrganic Chemistrynitric oxide; superoxide; peroxynitrite; protein tyrosine nitration; thiol oxidation; peroxynitrite scavengers; prostacyclin synthasechemistrylcsh:Biology (General)lcsh:QD1-999biology.proteinTyrosineCattleperoxynitrite scavengersProtein Processing Post-TranslationalInternational journal of molecular sciences
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Estimation of the Time-Variant Velocity of a Single Walking Person in Two-Dimensional Non-Stationary Indoor Environments Using Radio-Frequency Techni…

2020

Accurate estimation of the time-variant (TV) velocity of moving persons/objects in indoor spaces is of crucial importance for numerous wireless indoor applications. This article introduces a novel iterative procedure to estimate the TV velocity, i.e., TV speed and TV angle-of-motion (AOM), of a single moving person in 2D indoor environments by using radio-frequency (RF) techniques. The indoor area is equipped with a distributed 2 × 2 multiple-input multiple-output (MIMO) system. The proposed method is divided into two parts. In the first part, we estimate the path gains and the instantaneous Doppler frequencies by fitting the exact spectrograms of the complex channel gains of a 2D no…

time-variant velocity estimationEstimationGeneral Computer ScienceComputer scienceReal-time computingGeneral EngineeringDoppler characteristicsdistributed multiple-input multiple-output systemsnon-stationary indoor channelsGeneral Materials ScienceHuman activity of daily lifelcsh:Electrical engineering. Electronics. Nuclear engineeringRadio frequencylcsh:TK1-9971VDP::Teknologi: 500::Informasjons- og kommunikasjonsteknologi: 550
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Method and Practical Guidelines for Overcoming Enterprise Architecture Adoption Challenges

2017

During the last few years, interest towards Enterprise Architecture (EA) has increased, not least due to anticipated benefits resulting from adopting it. For instance, EA has been argued to provide cost reduction, technology standardisation, process improvement, and strategic differentiation. Despite these benefits, the EA adoption rate and maturity are still low. Consequently, EA benefits are not realised. A major reason hindering the adoption is that EA is not understood correctly. This paper aims for minimising the effect of the lack of understanding EA to adopting EA. Based on the research conducted in Finnish public sector, we propose an improved Enterprise Architecture Adoption Method…

toimintaohjeetKnowledge managementProcess managementbusiness.industryComputer sciencedesign scienceComputingMethodologies_MISCELLANEOUS05 social sciencesPublic sectorDelphi methodEnterprise integrationEnterprise architecture02 engineering and technologyEnterprise information security architectureDesign scienceDelphiCost reductionEnterprise architecture management0502 economics and business0202 electrical engineering electronic engineering information engineeringadoption method020201 artificial intelligence & image processingkokonaisarkkitehtuuribusiness050203 business & management
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Macierzyństwo adopcyjne jako zadanie rozwojowe

2017

tożsamość rodzicielskaadopcja
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Alla ricerca dell'i"rrintracciabile" Elena Ferrante

2019

Il saggio muove dal topos della sparizione, della perdita delle tracce, da cui prende avvio “L’amica geniale” rinvenendovi, pur nell’assenza di reali riscontri biografici, un inevitabile riverbero autobiografico. Si prova così, accogliendo alcune riflessioni della scrittrice, a ricostruire una storia di intelligenza compositiva, a sciogliere la sintassi dei sentimenti che solo le movenze della scrittura possono svelare. E all’esercizio vitale della scrittura si estende pure il topos del doppio che vede Elena e Lila bambine progettare di scrivere insieme un romanzo. Da questo primo snodo critico si passa a intessere una sottile trama intertestuale tra alcuni passaggi della tetralogia e il ra…

tracce libertà scrittura autobiografia donne doppiogioco fantasma
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