Search results for "DORSAL"

Increase of the FGFR1 signaling in the FGFR1-5-HT1A heteroreceptor complex in midbrain raphe 5-HT neuron systems via allosteric receptor-receptor int…

2015

The ascending midbrain 5-HT neurons known to contain 5-HT1A autoreceptors may be dysregulated in depression due to a reduced trophic support. New findings show existence of FGFR1-5-HT1A heteroreceptor complexes in the rat hippocampus with a partial characterization of their interface and in midbrain raphe 5-HT nerve cells. With in situ Proximity Ligation Assay (PLA) and supported by co-location of the FGFR1 and 5-HT1A immunoreactivities in midbrain raphe 5-HT cells, evidence for the existence of FGFR1-5-HT1A heteroreceptor complexes were obtained in the dorsal and median raphe nuclei of the Sprague–Dawley rat. Their existence in the rat medullary raphe RN33B cell cultures was also establish…

Do properties and species of weed seeds affect their consumption by carabid beetles?

2019

International audience; Seed predators are an integral part of agroecosystems, where they can reduce the populations of weeds. The preference of predators for seeds and the observed predation rate may be affected by the properties of seeds (e.g. taxonomy, chemical composition, physical defence). In this work, we focused on seed consumption of Taraxacum officinale Web. and Stellaria media (L.) Vill., from France and the Czech Republic, by three species of ground beetle that are seed predators (Coleoptera: Carabidae): Poecilus cupreus (L.), Pterostichus melanarius (Illiger) and Anchomenus dorsalis (Pontoppidan). The seed species were offered in arenas, simultaneously, under three different ex…

Co-expression of the voltage-gated potassium channel Kv1.4 with transient receptor potential channels (TRPV1 and TRPV2) and the cannabinoid receptor …

2006

Potassium channels contribute to basic neuronal excitability and modulation. Here, we examined expression patterns of the voltage-gated potassium channel Kv1.4, the nociceptive transduction channels TRPV1 and TRPV2 as well as the putative anti-nociceptive cannabinoid receptor CB1 by immunofluorescence double-labelings in sections of rat dorsal root ganglia (DRGs). Kv1.4, TRPV1 and CB1 were each detected in about one third of neurons (35.7+/-0.5%, 29.4+/-1.1% and 36.4+/-0.5%, respectively, mean diameter 19.1+/-0.3 microm). TRPV2 was present in 4.4+/-0.4% of all neurons that were significantly larger in diameter (27.4+/-0.7 microm; P < 0.001). Antibody double-labeling revealed that the majori…

Relationship between the caudate nucleus and the dorsal hippocampus, in the cat.

1972

The GABAergic system of the dorsal cortex of lizards: a combined HRP-GABA immunohistochemistry study.

1990

Abstract γ-Aminobutyric acid (GABA)-like immunoreactive (GABA-LI) neurons were found throughout the mediolateral and rostrocaudal axis of the dorsal cortex. They were horizontal, vertical and multipolar cells, mainly distributed in layers 1 and 3. GABA-LI boutons were diffusely distributed in layers 1 and 3, as well as forming basket-like images around layer 2 pyramidal perikarya. Double labelling experiments indicate that GABA-LI cells are an origin of and a target for rostrocaudal intrinsic projections within the dorsal cortex.

Multiple mechanisms of secondary hyperalgesia

2000

Publisher Summary This chapter discusses the multiple mechanisms of secondary hyperalgesia. The chapter defines the minimal conditions of complexity that must be fulfilled by a model of plasticity of spinal nociceptive transmission in order to explain clinical and psychophysical observations in humans. Secondary hyperalgesia is characterized by a leftward shift of the stimulus-response function for noxious mechanical stimuli. In order to define the afferent pathways involved in inducing central sensitization and in mediating the hyperalgesia to noxious mechanical stimuli, several psychophysical experiments using selective nerve block techniques is performed. Secondary hyperalgesia is likely…

The Argument Dependency Model

2015

This chapter summarizes the architecture of the extended Argument Dependency Model (eADM), a model of language comprehension that aspires toward neurobiological plausibility. It combines design principles from neurobiology with insights on cross-linguistic diversity. Like other current models, the eADM posits that auditory language processing proceeds along two distinct streams in the brain emanating from auditory cortex: the antero-ventral and postero-dorsal streams. Both streams are organized hierarchically and information processing takes place in a cascaded fashion. Each stream has functionally unified computational properties congruent with its role in primate audition. While the dorsa…

Dorsal Column Nuclei Neural Signal Features Permit Robust Machine-Learning of Natural Tactile- and Proprioception-Dominated Stimuli

2020

Neural prostheses enable users to effect movement through a variety of actuators by translating brain signals into movement control signals. However, to achieve more natural limb movements from these devices, the restoration of somatosensory feedback is required. We used feature-learnability, a machine-learning approach, to assess signal features for their capacity to enhance decoding performance of neural signals evoked by natural tactile and proprioceptive somatosensory stimuli, recorded from the surface of the dorsal column nuclei (DCN) in urethane-anesthetized rats. The highest performing individual feature, spike amplitude, classified somatosensory DCN signals with 70% accuracy. The hi…

Artificial neural networks for predicting dorsal pressures on the foot surface while walking

2012

In this work, artificial neural networks (ANNs) are proposed to predict the dorsal pressure over the foot surface exerted by the shoe upper while walking. A model that is based on the multilayer perceptron (MLP) is used since it can provide a single equation to model the exerted pressure for all the materials used as shoe uppers. Five different models are produced, one model for each one of the four subjects under study and an overall model for the four subjects. The inputs to the neural model include the characteristics of the material and the positions during a whole step of 14 pressure sensors placed on the foot surface. The goal is to find models with good generalization capabilities, (…

From the Golgi-Cajal mapping to the transmitter-based characterization of the neuronal networks leading to two modes of brain communication: Wiring a…

2007

After Golgi-Cajal mapped neural circuits, the discovery and mapping of the central monoamine neurons opened up for a new understanding of interneuronal communication by indicating that another form of communication exists. For instance, it was found that dopamine may be released as a prolactin inhibitory factor from the median eminence, indicating an alternative mode of dopamine communication in the brain. Subsequently, the analysis of the locus coeruleus noradrenaline neurons demonstrated a novel type of lower brainstem neuron that monosynaptically and globally innervated the entire CNS. Furthermore, the ascending raphe serotonin neuron systems were found to globally innervate the forebrai…