Search results for "DOT"

showing 10 items of 5147 documents

Religione e politica in Niccolò Tommaseo

2008

Cattolicesimo liberaleSettore SPS/02 - Storia Delle Dottrine PoliticheRisorgimentoConfederalismo
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Recensione a: C. Giurintano, Riformismo e liberalismo in Augustin Cochin (1823-1872), Firenze, Centro Editoriale Toscano, 2007

2009

Il lavoro di Claudia Giurintano analizza il pensiero e l’opera di Augustin Cochin, che può considerarsi come uno dei più qualificati rappresentanti del cattolicesimo sociale francese. Attraverso molteplici e documentate comparazioni teoriche, che attestano quanto sia stata capillare la circolazione delle idee nell’Europa ottocentesca, da questo volume su Cochin riceviamo un interessante approfondimento delle trame intellettuali e politiche su cui è stato chiamato a muoversi e a maturare l’incontro dei cattolici con le nuove caratterizzazioni storiche assunte dalla libertà e dalla democrazia.

Cattolicesimo sociale francese Ottocento neoguelfismo democrazia popolarismoSettore SPS/02 - Storia Delle Dottrine Politiche
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I candidati cattolici siciliani alle elezioni del primo Parlamento unitario

2012

With the use of newspapers, manuscripts, letters and speeches, the article analyses the admission of Sicilian Catholic deputies in the first national Parliament, like Emerico Amari, Vito d’Ondes Reggio and Gregorio Ugdulena. It underlines their political programs, beliefs and the idea of political representation as an action that was in the best interest of the represented people. In the background there was a steady claim to Legazia Apostolica that could have continued to exist only in a system of regional autonomy. According to the Sicilian deputies, the national deputy’s mandate had to be based on administrative freedom and there was a need for institutional solutions to ensure the prosp…

Cattolici siciliani Parlamento unitario Vito d'Ondes Reggio Emerico Amari Gregorio UgdulenaSettore SPS/02 - Storia Delle Dottrine Politiche
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La settimana sociale di Palermo al vaglio della stampa locale

2010

Il contributo propone un'analisi critica degli interventi dei cattolici alla settimana sociale di Palermo del 1908, utilizzando come fonti anche gli articoli pubblicati sulla stampa locale (Giornale di Sicilia, L'Ora, La Battaglia, Piff! Paff, La Sicilia cattolica, Letture domenicali, Il Centro etc.)

Cattolici siciliani Settimana socialeSettore SPS/02 - Storia Delle Dottrine Politiche
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Cattolici, politica e società in Piemonte tra '800 e '900, di Walter E. Crivellin.

2009

Il libro offre un interessante spaccato della Chiesa e della società piemontese tra il XIX e XX secolo.

Cattolici PiemonteSettore SPS/02 - Storia Delle Dottrine Politiche
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An affordable method to obtain cultured endothelial cells from peripheral blood

2013

The culture of endothelial progenitor cells (EPC) provides an excellent tool to research on EPC biology and vascular regeneration and vasculogenesis. The use of different protocols to obtain EPC cultures makes it difficult to obtain comparable results in different groups. This work offers a systematic comparison of the main variables of most commonly used protocols for EPC isolation, culture and functional evaluation. Peripheral blood samples from healthy individuals were recovered and mononuclear cells were cultured. Different recovery and culture conditions were tested: blood volume, blood anticoagulant, coating matrix and percentage of foetal bovine serum (FBS) in culture media. The succ…

Cell Culture TechniquesNeovascularization PhysiologicSangBlood volumeCell SeparationPeripheral blood mononuclear cellUmbilical veinvasculogenesisAndrologyVasculogenesisCell AdhesionHuman Umbilical Vein Endothelial CellsmedicineHumansProgenitor cellCells CulturedCell Proliferationendothelial progenitor cellsFisiologia cel·lularcell cultureBlood CellsbiologyStem CellsReproducibility of ResultsOriginal ArticlesCell BiologyHeparinFibronectinCell cultureImmunologyembryonic structuresbiology.proteincardiovascular systemMolecular Medicinemedicine.drugcirculatory and respiratory physiology
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Bacillus thuringiensis Cry1Ac Toxin-Binding and Pore-Forming Activity in Brush Border Membrane Vesicles Prepared from Anterior and Posterior Midgut R…

2008

ABSTRACT It is generally accepted that Bacillus thuringiensis Cry toxins insert into the apical membrane of the larval midgut after binding to specific receptors, and there is evidence that the distribution of binding molecules along the midgut is not uniform. By use of the voltage-sensitive dye DiSC 3 (5) and 125 I-labeled Cry1Ac, we have measured the effect of Cry1Ac in terms of permeabilization capacity and of binding parameters on brush border membrane vesicles (BBMV) prepared from the anterior and the posterior regions of the larval midgut from two insect species, Manduca sexta and Helicoverpa armigera . The permeabilizing activity was significantly higher with BBMV from the posterior …

Cell Membrane PermeabilityBrush bordermedia_common.quotation_subjectBacterial ProteinInsectApplied Microbiology and BiotechnologyIodine RadioisotopeIodine RadioisotopesHemolysin ProteinsEndotoxinBacterial ProteinsManducaBacillus thuringiensisInvertebrate MicrobiologyAnimalsmedia_commonBacillus thuringiensis ToxinsMicrovilliEcologybiologyAnimalVesiclefungiMidgutHemolysin ProteinApical membraneAlkaline Phosphatasebiology.organism_classificationEndotoxinsEnzyme ActivationLepidopteraBiochemistryManduca sextaLarvaPotassiumBiophysicsManducaDigestive SystemProtein BindingFood ScienceBiotechnologyApplied and Environmental Microbiology
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Toxicity and mode of action of Bacillus thuringiensis Cry proteins in the Mediterranean corn borer, Sesamia nonagrioides (Lefebvre)

2006

ABSTRACT Sesamia nonagrioides is one of the most damaging pests of corn in Spain and other Mediterranean countries. Bt corn expressing the Bacillus thuringiensis Cry1Ab toxin is being grown on about 58,000 ha in Spain. Here we studied the mode of action of this Cry protein on S. nonagrioides (binding to specific receptors, stability of binding, and pore formation) and the modes of action of other Cry proteins that were found to be active in this work (Cry1Ac, Cry1Ca, and Cry1Fa). Binding assays were performed with 125 I- or biotin-labeled toxins and larval brush border membrane vesicles (BBMV). Competition experiments indicated that these toxins bind specifically and that Cry1Aa, Cry1Ab, an…

Cell Membrane PermeabilityMembrane permeabilityBacterial ToxinsBacillus thuringiensisSesamia nonagrioidesBacterial ToxinBacterial ProteinZea maysApplied Microbiology and BiotechnologyOstriniaHemolysin ProteinsZea mayBacterial ProteinsEndotoxinBacillus thuringiensisBotanyInvertebrate MicrobiologyAnimalsBacillus thuringiensiBinding siteMode of actionPest Control BiologicalGenetically modified maizeBacillus thuringiensis ToxinsEcologybiologyMicrovilliAnimalfungifood and beveragesHemolysin Proteinbiology.organism_classificationPlants Genetically ModifiedEndotoxinsLepidopteraCry1AcBiochemistryLarvaFood ScienceBiotechnology
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PECAM-1 expression in human mesothelial cells: an in vitro study.

1996

Mesothelial cells are actively involved in inflammatory processes by expressing a set of cell adhesion molecules (CAMs). Transmigration of leukocytes into inflamed tissues requires a chemotactic stimulus and engagement of platelet-endothelial cell adhesion molecule-1 (PECAM-1). To investigate the kinetics involved in peritonitis, pure cultures of mesothelial cells are necessary. In previous studies, we have found that human mesothelial cells (HOMES) show a weak constitutive expression of PECAM-1, which cannot be further stimulated by cytokines. It is known that all serous cavities and body fluids contain numerous macrophages which strongly express this adhesion molecule. To identify the cel…

Cell SeparationIn Vitro TechniquesEpitheliumPathology and Forensic MedicineInterferon-gammaE-selectinmedicineHumansCell adhesionMolecular BiologyCells CulturedbiologyChemistryCell adhesion moleculeTumor Necrosis Factor-alphaMonocyteEpithelial CellsCell BiologyGeneral MedicineCell sortingMolecular biologyImmunohistochemistryRecombinant ProteinsCell biologyPlatelet Endothelial Cell Adhesion Molecule-1Microscopy Electronmedicine.anatomical_structureCell culturebiology.proteinNeural cell adhesion moleculeOmentumMesothelial CellInterleukin-1Pathobiology : journal of immunopathology, molecular and cellular biology
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Quinoline-Based Molecules Targeting c-Met, EGF, and VEGF Receptors and the Proteins Involved in Related Carcinogenic Pathways

2020

The quinoline ring system has long been known as a versatile nucleus in the design and synthesis of biologically active compounds. Currently, more than one hundred quinoline compounds have been approved in therapy as antimicrobial, local anaesthetic, antipsychotic, and anticancer drugs. In drug discovery, indeed, over the last few years, an increase in the publication of papers and patents about quinoline derivatives possessing antiproliferative properties has been observed. This trend can be justified by the versatility and accessibility of the quinoline scaffold, from which new derivatives can be easily designed and synthesized. Within the numerous quinoline small molecules developed as a…

Cell SurvivalAngiogenesisPharmaceutical ScienceAntineoplastic AgentsReviewMolecular Dynamics SimulationAnalytical Chemistrylcsh:QD241-441Structure-Activity Relationship03 medical and health scienceschemistry.chemical_compound0302 clinical medicinelcsh:Organic chemistryEpidermal growth factorquinolineDrug DiscoverySAR studieHumansPhysical and Theoretical Chemistrycarcinogenic pathwaysProtein kinase BPI3K/AKT/mTOR pathway030304 developmental biology0303 health sciencesantiproliferative compoundChemistryDrug discoveryOrganic ChemistryQuinolineBiological activityProto-Oncogene Proteins c-metantiproliferative compoundstargeted therapySettore CHIM/08 - Chimica FarmaceuticaSmall moleculeErbB Receptorscarcinogenic pathwayReceptors Vascular Endothelial Growth FactorSAR studiesChemistry (miscellaneous)030220 oncology & carcinogenesisQuinolinesCancer researchMolecular Medicinekinases modulatorkinases modulatorsbiological dataSignal TransductionMolecules
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