Search results for "DP"
showing 10 items of 10968 documents
Towards Improved Healthcare Performance: Examining Technological Possibilities and Patient Satisfaction with Wireless Body Area Networks
2009
Published version of an article from the journal: Journal of Medical Systems. he original publication is available at Springerlink. http://dx.doi.org/10.1007/s10916-009-9291-8 This paper investigates the benefits of using less intrusive wireless technologies for heart monitoring. By replacing well established heart monitoring devices (i.e. Holter) with wireless ECG based Body Area Networks (BAN), improved healthcare performance can be achieved, reflected in (1) high quality ECG recordings during physical activities and (2) increased patient satisfaction. A small scale clinical trial was conducted to compare both technologies and the results illustrate that the wireless ECG monitor was able …
The road to gold: Training and peaking characteristics in the year prior to a gold medal endurance performance
2014
Published version of an article in the journal PLoS ONE. Also available from the publisher at: http://dx.doi.org/10.1371/journal.pone.0101796 Open Access Purpose: To describe training variations across the annual cycle in Olympic and World Champion endurance athletes, and determine whether these athletes used tapering strategies in line with recommendations in the literature. Methods: Eleven elite XC skiers and biathletes (4 male; 28±1 yr, 85±5 mL. min-1. kg-1 V̇O2max, 7 female, 25±4 yr, 73±3 mL. min-1. kg-1 V̇O2max) reported one year of day-to-day training leading up to the most successful competition of their career. Training data were divided into periodization and peaking phases and dis…
Atypical CIDP: diagnostic criteria, progression and treatment response. Data from the Italian CIDP Database
2019
ObjectivesA few variants of chronic inflammatory demyelinating polyradiculoneuropathy (CIDP) have been described, but their frequency and evolution to typical CIDP remain unclear. To determine the frequency and characteristics of the CIDP variants, their possible evolution to typical CIDP, and treatment response.MethodsWe applied a set of diagnostic criteria to 460 patients included in a database of Italian patients with CIDP. Clinical characteristics and treatment response were reviewed for each patient. The Kaplan-Meier curve was used to estimate the progression rate from atypical to typical CIDP.ResultsAt the time of inclusion, 376 (82%) patients had a diagnosis of typical CIDP while 84 …
Statement of severe trauma management in France; teachings of the FIRST study
2013
Abstract Introduction The blunt trauma victim management is still a matter of debate and comparing studies involving different emergency medical services and health care organization remains fictitious. Hence, the French Intensive care Recorded in Severe Trauma (FIRST) was conducted in order to describe the severe blunt trauma management in France. The present paper aimed at recalling the main results of FIRST study. Methods The FIRST study was based on a multicenter prospective cohort of patients aged 18 or over with severe exclusive blunt trauma requiring admission to university hospital care unit within the first 72 h and/or managed by medical-Staffed Emergency Mobile Unit (SMUR). Multip…
The Inclusion of Sprints in Low-Intensity Sessions During the Transition Period of Elite Cyclists Improves Endurance Performance 6 Weeks Into the Sub…
2021
Purpose: To investigate the effects of including repeated sprints in a weekly low-intensity (LIT) session during a 3-week transition period on cycling performance 6 weeks into the subsequent preparatory period (PREP) in elite cyclists. Methods: Eleven elite male cyclists (age = 22.0 [3.8] y, body mass = 73.0 [5.8] kg, height = 186 [7] cm, maximal oxygen uptake [VO2max] = 5469 [384] mL·min−1) reduced their training load by 64% and performed only LIT sessions (CON, n = 6) or included 3 sets of 3 × 30-second maximal sprints in a weekly LIT session (SPR, n = 5) during a 3-week transition period. There was no difference in the reduction in training load during the transition period between group…
Patients with adenoid cystic carcinomas of the salivary glands treated with lenvatinib: Activity and quality of life
2019
The treatment of patients with recurrent and/or metastatic (R/M) salivary gland adenoid cystic carcinoma (ACC) remains an unmet need.Patients with R/M disease with a history of clinical or symptomatic disease progression within 6 months and a maximum of 1 previous line of chemotherapy or a multiple kinase inhibitor received oral lenvatinib at a dose of 24 mg/day. The primary endpoint was the objective response rate; secondary endpoints included quality of life (QOL) (according to the European Organization for Research and Treatment of Cancer Quality of Life Questionnaire-Core 30 Items [EORTC QLQ-C30] and the European Organization for Research and Treatment of Cancer Quality of Life Question…
Prospective risk stratification of sudden cardiac death in Marfan's syndrome.
2013
Marfan syndrome (MFS) is a variable, autosomal-dominant disorder of the connective tissue. In MFS serious ventricular arrhythmias and sudden cardiac death (SCD) can occur. The aim of this prospective study was to reveal underlying risk factors and to prospectively investigate the association between MFS and SCD in a long-term follow-up.77 patients with MFS were included. At baseline serum N-terminal pro-brain natriuretic peptide (NT-proBNP), transthoracic echocardiogram, 12-lead resting ECG, signal-averaged ECG (SAECG) and a 24-h Holter ECG with time- and frequency domain analyses were performed. The primary composite endpoint was defined as SCD, ventricular tachycardia (VT), ventricular fi…
Personality, Risk Perceptions, and Health Behaviors: A Two-Wave Study on Reciprocal Relations in Adults
2022
The aim of the study was to examine reciprocal associations between risk perceptions for cardiovascular disease and health behaviors (i.e., physical activity, fruit/vegetable consumption), while accounting for key personality characteristics in middle-aged adults. Participants (N = 297; M (SD) age = 51 (6.95); 72.4% female) completed online questionnaires assessing risk perceptions, physical activity, fruit/vegetable consumption, and personality (conscientiousness and neuroticism) on two occasions, one week apart. Physical activity did not have a statistically significant effect on risk perception over time (b = −0.00, p = 0.227). However, fruit and vegetable consumption (b = −0…
Device-measured physical activity, adiposity and mortality: a harmonised meta-analysis of eight prospective cohort studies.
2021
BackgroundThe joint associations of total and intensity-specific physical activity with obesity in relation to all-cause mortality risk are unclear.MethodsWe included 34 492 adults (72% women, median age 62.1 years, 2034 deaths during follow-up) in a harmonised meta-analysis of eight population-based prospective cohort studies with mean follow-up ranging from 6.0 to 14.5 years. Standard body mass index categories were cross-classified with sample tertiles of device-measured total, light-to-vigorous and moderate-to-vigorous physical activity and sedentary time. In five cohorts with waist circumference available, high and low waist circumference was combined with tertiles of moderate-to-vigor…
Teprotumumab for Thyroid-Associated Ophthalmopathy
2017
Thyroid-associated ophthalmopathy, a condition commonly associated with Graves' disease, remains inadequately treated. Current medical therapies, which primarily consist of glucocorticoids, have limited efficacy and present safety concerns. Inhibition of the insulin-like growth factor I receptor (IGF-IR) is a new therapeutic strategy to attenuate the underlying autoimmune pathogenesis of ophthalmopathy.We conducted a multicenter, double-masked, randomized, placebo-controlled trial to determine the efficacy and safety of teprotumumab, a human monoclonal antibody inhibitor of IGF-IR, in patients with active, moderate-to-severe ophthalmopathy. A total of 88 patients were randomly assigned to r…