Search results for "DPC"
showing 10 items of 10 documents
Circulating Tumor DNA Detection by Digital-Droplet PCR in Pancreatic Ductal Adenocarcinoma: A Systematic Review
2021
Simple Summary Pancreatic cancer is a digestive tumor that is most difficult to treat and carries one of the worst prognoses. The anatomical location of the pancreas makes it very difficult to obtain enough tumor material to establish a molecular diagnosis, so knowing the biology of this tumor and implementing new targeted-therapies is still a pending issue. The use of liquid biopsy, a blood sample test to detect circulating-tumor DNA fragments (ctDNA), is key to overcoming this difficulty and improving the evolution of this tumor. Liquid biopsies are equally representative of the tissue from which they come and allow relevant molecular and diagnostic information to be obtained in a faster …
Uplink DPCCH Gating of Inactive UEs in Continuous Packet Connectivity Mode for HSUPA
2007
In order to further improve the packet performance in the UMTS FDD system, uplink dedicated physical control channel (DPCCH) gating as a scheme is proposed in 3GPP under the work item "continuous connectivity for packet data users". In this paper, the uplink DPCCH gating concept is described and analyzed on both a qualitative and a quantitative level. And the system performance of different gating patterns used in the scheme was investigated by analytical prediction and system level simulations with different channel profiles. As shown, the selection of the gating pattern has a significant influence on the system performance, which is correlated with the uplink data transmission activity an…
Guava (Psidium guajava L.) Leaf Extract as Bioactive Substances for Anti-Androgen and Antioxidant Activities
2022
Leaves of guava (Psidium guajava L.) have been used in Thai folk medicine without any supporting evidence as a traditional herbal remedy for hair loss. Androgenetic alopecia (AGA) is chronic hair loss caused by effects of androgens in those with a genetic predisposition, resulting in hair follicle miniaturization. Our objectives were to provide the mechanistic assessment of guava leaf extract on gene expressions related to the androgen pathway in well-known in vitro models, hair follicle dermal papilla cells (HFDPC), and human prostate cancer cells (DU-145), and to determine its bioactive constituents and antioxidant activities. LC-MS analysis demonstrated that the main components of the et…
DISEASES DIVERSITY FOR FLAX GENETIC RESOURCES IN LATVIA
2017
Flax ( Linum usitatissimum L) yield of stem and seeds and them quality is influenced by a number of harmful diseases but investigation about pathogens in recent years have not been done in Latvia. Each stage of development of disease is important in the pathogen life cycle and requires certain condition. Goal of this study have identify possibilities of the pathogens and were assess disease severity depending on the genotypes on flax in variable environmental conditions. The resistance to the diseases for 24 flax genotypes and standard variety ‘Vega 2’ were evaluated. The field trials have been carried out over the period from 2015 to 2016 at the Research Centre of Priekuli, part of Vilani…
Electronic functionality of Gd-bisphthalocyanine: Charge carrier concentration, charge mobility, and influence of local magnetic field
2018
Abstract Gadolinium bisphthalocyanine (GdPc2) has been placed among the highest ranked molecular materials considered namely for modern optoelectronic applications including organic solar cells. To improve understanding of the correlation between GdPc2 magnetic properties and its electronic functionality, we experimentally and theoretically studied charge carrier concentration, charge mobility, and influence of local magnetic field on charge carrier transport. For better clearance, all the main studied properties of GdPc2 bisphthalocyanine were compared with Zn phthalocyanine (ZnPc) as a reference material. Conductivity and charge carrier mobility were measured in materials incorporated in …
Responsabilité Sociale des Organisations (RSO) et New Public Management (NPM) : Logiques contradictoires ou complémentaires dans une organisation pub…
2021
International audience; Les professionnels de santé doivent s'inscrire dans une démarche de formation médicale continue. Celle-ci est réglementée par le Développement Professionnel Continu (DPC), un dispositif initié en 2009 par la loi dite HPST (Hôpital, Patients, Santé et Territoires). Depuis 2016, le DPC est géré par l'Agence Nationale du DPC (ANDPC), un groupement d'intérêt public (GIP) constitué paritairement entre l'État et l'Union Nationale des Caisses d'Assurance Maladie (UNCAM). L'objectif de l'ANDPC est par conséquent de mieux former les professionnels de santé dans un souci d'optimisation des coûts. Cela représente un véritable enjeu sociétal dans le cadre de l'évaluation des pol…
Dynamic Packet Bundling for VoIP Transmission Over Rel'7 HSUPA with 10ms TTI Length
2007
In this paper, the system level optimization of the voice over IP transmission in the HSUPA system, configured with a 10 ms TTI length, is analyzed. The study considers the release 7 improvements to HSUPA, in terms of the DPCCH gating concept. A dynamic activated MAC layer bundling of two VoIP packets in a single frame is proposed and compared against the single packet per frame transmission by means of quasi-static system level simulations.
Améliorer la méthodologie standard de la qPCR pour l’analyse de la densité microbienne dans la plateforme GenoSol. Mémoire de stage BTS de 2ème année…
2019
Le stage a été dédié à la comparaison de la méthode de ddPCR à celle de la PCR quantitative pour évaluer le nombre de copies de gènes 16S dans un échantillon d’ADN extrait de sol.
DNA recovery from Droplet Digital™ PCR emulsions using liquid nitrogen
2020
Droplet microfluidics is a technology that enables the production and manipulation of small volumes. In biosciences, the most popular application of this technology is Droplet Digital™ PCR (ddPCR™), where parallel nanoliter-scale PCR assays are used to provide a high sensitivity and specificity for DNA detection. However, the recovery of PCR products for downstream applications such as sequencing can be challenging due to the droplets' stability. Here we compared five methods for disrupting the droplets to recover DNA. We found that rapid freezing in liquid nitrogen results in a clear phase separation and recovery of up to 70% of the DNA content. Liquid nitrogen freezing can thus offer a si…
RNS biomarķieru analīze prostatas vēža pacientu plazmas un urīna ekstracelulārajās vezikulās
2022
Ekstracelulārās vezikulas (EVs) ir heterogēni, ar membrānu norobežoti pūslīši, kas satur dažādas makromolekulas, tai skaitā RNS. EVs izdala visu veidu organisma šūnas un tās atrodas visos cilvēka bioloģiskajos šķidrumos. Ir pierādīta to loma prostatas vēža (PV) attīstībā, progresijā un metastazēšanās procesos. Šajā darbā iekļauta astoņu potenciālo RNS biomarķieru analīze PV un labdabīgas prostatas hiperplāzijas (LPH) pacientu plazmas un urīna EVs, kā arī PV pacientiem pirms un pēc radikālas prostatektomijas, izmantojot pilienu digitālo PCR. Tika novērota būtiska miR-375, piR-28004 un AMD1 līmeņa samazināšanās urīna EVs pēc radikālas prostatektomijas un tie tika izvirzīti kā potenciāli RNS b…