Search results for "DPPH"

showing 10 items of 137 documents

Anti-inflammatory and antioxidant activities of Jungia paniculata.

2010

The present study was conducted to evaluate the antioxidant and anti-inflammatory activities of Jungia paniculata (DC.) A. Gray (Asteraceae), used traditionally in Peru. The dry leaves were extracted with methanol, 50% methanol, and water. The anti-inflammatory activity of this plant was studied using in vitro (nitric oxide production in RAW 264.7 macrophages and sPLA(2) inhibition assay) and in vivo (carrageenan-induced paw edema in rats and TPA-induced ear edema in mice) model systems. The antioxidant activity of extracts was studied using three in vitro model systems (DPPH(*) radical-scavenging assay, ABTS(*+) assay, and superoxide radical-scavenging activity). The results have been corr…

MaleAntioxidantmedicine.drug_classDPPHmedicine.medical_treatmentPharmaceutical ScienceAsteraceaeAnti-inflammatoryAntioxidantsNitric oxidechemistry.chemical_compoundMiceIn vivoDrug DiscoverymedicineAnimalsEdemaMTT assayRats WistarCells CulturedPharmacologyTraditional medicinebiologyChemistryPlant ExtractsMacrophagesAnti-Inflammatory Agents Non-SteroidalGeneral MedicineEnzyme assayRatsPlant LeavesComplementary and alternative medicineBiochemistryPolyphenolbiology.proteinMolecular MedicinePharmaceutical biology
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Studies on the antioxidant activity of the essential oil and extract of Tunisian Tetraclinis articulata (Vahl) Mast. (Cupressaceae).

2013

This study analyses the chemical composition and in vitro antioxidant activity of both the essential oil and the 80% aqueous acetone extract of Tetraclinis articulata leaves. The GC-MS analysis of the essential oil identified 66 components that comprise 93.5% of the oil. The major constituents of the oil are: bornyl acetate (31.4%), α-pinène (24.5%) and camphor (20.3%). Antioxidant activities of the samples were determined using four different test systems, namely DPPH, β-carotene/linoleic acid, reducing power and metal chelating activity assay. Test results from the DPPH system showed the strongest radical scavenging activity was exhibited by the 80% aqueous acetone extract (IC(50) = 5.5 µ…

Metal chelating activityAntioxidantDPPHmedicine.medical_treatmentLinoleic acidMetal chelating activityPlant ScienceTetraclinisBiochemistryEssential oilAntioxidantsGas Chromatography-Mass SpectrometryAnalytical Chemistrylaw.inventionLinoleic Acidchemistry.chemical_compoundCamphorAntioxidant activityPicrateslawmedicineOils VolatileOrganic chemistryFood scienceEssential oilCarotene/linoleic acidbiologyPlant ExtractsOrganic ChemistryBiphenyl CompoundsCupressaceaePolyphenolsSettore CHIM/06 - Chimica Organicabiology.organism_classificationbeta CaroteneTetraclinis articulataPlant LeavesProanthocyanidinchemistryReducing powerDPPHNatural product research
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Comparison of Two Schizophyllum commune Strains in Production of Acetylcholinesterase Inhibitors and Antioxidants from Submerged Cultivation

2021

In recent years, fungi have been recognized as producers of acetylcholinesterase (AChE) inhibitors, agents important for the prevention of Alzheimer’s disease (AD). This study aimed to examine the AChE inhibitory, the antioxidative and antibacterial activity of two different Schizophyllum commune strains that originated from Serbia (SRB) and Italy (IT). Submerged cultivation of grown mycelia (M) and fermentation broth (F) of ethanol (EtOH) and polysaccharide (PSH) extracts lasted for 7, 14, 21 and 28 days. For AChE activity Ellman method was performed, while for antioxidative activity, sevendifferent assays were conducted: DPPH, ABTS, FRAP, SOA, OH, NO together with total phenolic content. …

Microbiology (medical)Submerged cultivationAntioxidantDPPH<i>Schizophyllum commune</i>medicine.medical_treatmentAcetylcholinesterase inhibitionPlant ScienceSchizophyllum commune01 natural sciencesArticle03 medical and health scienceschemistry.chemical_compoundmedicineFood sciencelcsh:QH301-705.5Ecology Evolution Behavior and SystematicsMycelium030304 developmental biology0303 health sciencesABTSbiology010405 organic chemistrySettore BIO/02 - Botanica SistematicaSchizophyllum communebiology.organism_classificationAntimicrobialAcetylcholinesterase0104 chemical scienceslcsh:Biology (General)chemistrySettore BIO/03 - Botanica Ambientale E ApplicataAntioxidantAntibacterial activityJournal of Fungi
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Preparation of two sets of 5,6,7-trioxygenated dihydroflavonol derivatives as free radical scavengers and neuronal cell protectors to oxidative damag…

2009

An unusual class of 5,6,7-trioxygenated dihydroflavonols (3a-e and 4a-j) were designed and prepared. Their antioxidative properties were assessed by examining their capacities in several in vitro models, including superoxide anion and 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical scavenging, rat liver homogenate lipid peroxidation inhibition, PC12 cells protection from oxidative damage, and xanthine oxidase inhibition. These dihydroflavonols displayed positive quenching abilities towards O(2)(-) and DPPH free radicals, in which the majority exhibited superior antioxidant properties to Vitamin C. cis-Configurated compound (+/-)-3e demonstrated remarkable inhibition to LPO with an IC(50) value…

Models MolecularXanthine OxidaseAntioxidantFlavonolsmedicine.drug_classDPPHmedicine.medical_treatmentClinical BiochemistryMolecular ConformationPharmaceutical Sciencemedicine.disease_causeBiochemistryPC12 CellsAntioxidantsLipid peroxidationRats Sprague-Dawleychemistry.chemical_compoundStructure-Activity RelationshipDrug DiscoverymedicineAnimalsXanthine oxidaseMolecular BiologyXanthine oxidase inhibitorNeuronsSuperoxideOrganic ChemistryFree Radical ScavengersFree radical scavengerRatschemistryBiochemistryMolecular MedicineLipid PeroxidationReactive Oxygen SpeciesOxidative stressBioorganicmedicinal chemistry
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Influence of Laccase and Tyrosinase on the Antioxidant Capacity of Selected Phenolic Compounds on Human Cell Lines

2015

Polyphenolic compounds affect the color, odor and taste of numerous food products of plant origin. In addition to the visual and gustatory properties, they serve as radical scavengers and have antioxidant effects. Polyphenols, especially resveratrol in red wine, have gained increasing scientific and public interest due to their presumptive beneficial impact on human health. Enzymatic oxidation of phenolic compounds takes place under the influence of polyphenol oxidases (PPO), including tyrosinase and laccase. Several studies have demonstrated the radical scavenger effect of plants, food products and individual polyphenols in vitro, but, apart from resveratrol, such impact has not been prove…

Monophenol MonooxygenasePlant Extracts530 PhysicsoxidationDPPH•food and beveragesantioxidant activitytyrosinase530 Physikcell culturesArticleAntioxidantsCell LinelaccaseFungal Proteinslcsh:QD241-441lcsh:Organic chemistryHumansOxidation-ReductionpolyphenolsMolecules
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Characterization of softwood and hardwood lignoboost kraft lignins with emphasis on their antioxidant activity

2014

Fractionation of softwood and hardwood LignoBoost kraft lignins, using sequential extraction with organic solvents of increasing hydrogen-bonding ability (dichloromethane, n-propanol, and methanol), was carried out. Using SEC, analytical pyrolysis, FTIR and UV/VIS spectroscopy, and chemical analytical methods, four fractions were obtained and characterized in terms of their yield, composition, functionality, lignin structural features, and antioxidant properties. In tests with free radicals (ABTS●+, DPPH●, O2●-) and the ORAC (oxygen radical absorbance capacity) assay, the high radical scavenging capacity of the lignin’s soluble fractions was demonstrated. The antioxidant activity of the fra…

ORAC assayEnvironmental EngineeringSoftwoodABTSOxygen radical absorbance capacityLignoBoost kraft ligninDPPHAntioxidant propertieslcsh:Biotechnologytechnology industry and agricultureBioengineeringmacromolecular substancesFractionationDPPH●chemistry.chemical_compoundchemistryABTS●+lcsh:TP248.13-248.65HardwoodOrganic chemistryLigninSolvent fractionationWaste Management and DisposalKraft paperO2●- assays
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ORAC and TEAC assays comparison to measure the antioxidant capacity of food products

2009

Abstract Oxygen radical antioxidant capacity (ORAC) and trolox equivalent antioxidant capacity (TEAC) assays were compared to estimate the total antioxidant capacity (TAC) of orange juice, milk, and an orange juice-milk beverage. When the TEAC method was used with this beverage, an increase in the concentration of orange juice corresponded to an increase in TAC, but increasing the percentage of milk did not increase the TAC value. When the ORAC method was applied, it was seen that increased concentrations of juice or milk corresponded to greater antioxidant capacity. An evaluation was also made of the influence of certain compounds (ascorbic acid, gallic acid, β-carotene, lutein, zeaxanthin…

Orange juiceLuteinDPPHTrolox equivalent antioxidant capacityfood and beveragesGeneral MedicineOrange (colour)Ascorbic acidAnalytical ChemistryZeaxanthinchemistry.chemical_compoundchemistryGallic acidFood scienceFood ScienceFood Chemistry
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Nutraceutical Value of Pantelleria Capers (Capparis spinosa L.)

2019

Abstract: Unopened flower buds of Capparis spinosa L. (capers), generally used in the Mediterranean area as food flavoring, are known to be a good source of bioactive compounds. The aim of this work was to evaluate the nutraceutical value of salt-fermented capers collected from different areas of Pantelleria Island (Italy), testing their methylglyoxal and glyoxal trapping capacity and antioxidant activity by 2,2-diphenyl-1-picryl hydrazyl (DPPH), [2,2-azinobis(3-ethylben- zothiazoline-6-sulfonic acid)] diammonium salt (ABTS), and oxygen radical absorbance capacity (ORAC) assays. Hydrophilic extracts were also characterized by high-performance liquid chromatography–electrospray ionization/ma…

Oxygen radical absorbance capacity030309 nutrition & dieteticsDPPHFlavonoidGlucosinolatesAntioxidantsCapparis spinosa03 medical and health scienceschemistry.chemical_compound0404 agricultural biotechnologyfoodFlavonolsPhenolsnutraceutical propertiesFood scienceKaempferolsChromatography High Pressure LiquidPantelleria Island caperschemistry.chemical_classificationFlavonoids0303 health sciencesABTSPlant ExtractsCapparis spinosa04 agricultural and veterinary sciencesnutraceutical propertie040401 food sciencefood.foodSettore AGR/03 - Arboricoltura Generale E Coltivazioni ArboreeCapparischemistryItalymethylglyoxal and glyoxal trapping capacityhydrophilic extract compositionDietary SupplementsSeedsQuercetinQuercetinKaempferolFood Science
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Water as a Solvent of Election for Obtaining Oleuropein-Rich Extracts from Olive (Olea europaea) Leaves

2021

Leaves from Olea europaea represent one of the main by-products of the olive oil industry, containing a plethora of bioactive compounds with several promising activities for human health. An organic solvent-free extraction method was developed for the recovery of olive leaf phenols, which obtained an extract containing oleuropein in high amounts. A comparison of various extraction media is reported, together with the total phenolic content, DPPH (2,2-Diphenyl-1-picrylhydrazyl) content, ORAC (oxygen radical absorbance capacity), and polyphenol oxidase activity of the corresponding extracts. The polyphenol profiles and content of the most representative extracts have also been studied. Extrac…

Oxygen radical absorbance capacityDPPHradical scavenging activity01 natural sciencesaqueous extractionlcsh:Agriculturechemistry.chemical_compound0404 agricultural biotechnologyOlive leafOleuropeinPhenolsFood scienceOlea europaeabiology010401 analytical chemistryExtraction (chemistry)lcsh:S04 agricultural and veterinary sciencesbiology.organism_classification040401 food science0104 chemical scienceschemistryPolyphenolOleabioactive compounds recoveryoleuropein<i>Olea europaea</i>Agronomy and Crop ScienceAgronomy
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Effect of cactus pear (Opuntia ficus-indica (L.) Miller) on the antioxidant capacity of donkey milk

2017

The cladodes of Opuntia ficus‐indica (L.) Miller were fed to lactating donkeys as an alternative food, in order to evaluate effects on the chemical composition and antioxidant activity of their milk. Lactating donkeys were divided into two groups: standard feeding and alternative feeding. With regard to chemical composition, no differences were observed. Total antioxidant capacity was constant in the standard feeding group, while it increased in the alternative feeding group: the radical scavenging activity increased from 95.53% to 96.62% in the ABTS test and from 28.40% to 33.33% in the DPPH test. This indicated that alternative feeding affects the antioxidant capacity of milk.

PEARAntioxidantABTSDPPHProcess Chemistry and Technologymedicine.medical_treatment0402 animal and dairy scienceBioengineering04 agricultural and veterinary sciencesBiologybiology.organism_classification040401 food science040201 dairy & animal scienceAntioxidant capacitychemistry.chemical_compound0404 agricultural biotechnologychemistryCactusmedicineCladodesFood scienceDonkeyFood ScienceInternational Journal of Dairy Technology
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