Search results for "DUP"
showing 10 items of 499 documents
Patients Withdrawing Dupilumab Monotherapy for COVID-19-Related Reasons Showed Similar Disease Course Compared With Patients Continuing Dupilumab The…
2022
N/A
Dupin aîné avocat, un juriste entre l’ancien et le nouveau droit
2013
International audience
The Diagnosis and Treatment of Peripheral Arterial Vascular Disease
2016
Background In peripheral arterial occlusive disease (PAOD), arterial stenosis or occlusion impairs perfusion in the territory of the distal portion of the aorta and the iliac and leg arteries. In Germany, the prevalence of PAOD rises with age, reaching 20% among persons over age 70. Methods This guideline was prepared by a collaboration of 22 medical specialty societies and two patient self-help organizations on the basis of pertinent publications that were retrieved by a systematic search in PubMed for articles that appeared from 2008 to April 2014, with a subsequent update to May 2015. Results 294 articles were assessed, including 34 systematic reviews and 98 randomized controlled trials …
Memoria de lo acaecido en el exército del General Dupont : desde su entrada en Córdova en el dia 7 de junio del año 1808, hasta su rendición de resul…
Sign.: [A]4, B-E4 Notes a peu de pàg
Dupuytren's contracture and phenobarbital: Our case reports and review of the literature
2009
Background: Dupuytren’s contracture is a fibroproliferative condition involving the superficial palmar fascia, leading to a progressive and irreversible flexion of the fingers. In literature, there are different opinions regarding the phenobarbital, a common antiepileptic drug, and its effective role in the genesis and development of Dupuytren’s disease. In our this retrospective study the association between phenobarbital and Dupuytren’s contracture is discussed. Case Reports: Three patients in treatment with phenobarbital who had no others significant risk factors for Dupuytren’s contracture were included in this study. The disease occurred after one to four years of drug therapy, at dosa…
Accelerating short read mapping on an FPGA (abstract only)
2012
The explosive growth of short read datasets produced by high throughput DNA sequencing technologies poses a challenge to the mapping of short reads to a reference genome in terms of sensitivity and execution speed. Existing methods often use a restrictive error model for computing the alignments to improve speed, whereas more flexible error models are generally too slow for large-scale applications. Although a number of short read mapping software tools have been proposed, designs based on hardware are relatively rare. In this paper, we present a hybrid system for short read mapping utilizing both software and field programmable gate array (FPGA)-based hardware. The compute intensive semi-g…
A naïve approach to speed up portfolio optimization problem using a multiobjective genetic algorithm
2012
a b s t r a c t Genetic algorithms (GAs) are appropriate when investors have the objective of obtaining mean-variance (VaR) efficient frontier as minimising VaR leads to non-convex and non-differential risk-return optimisation problems. However GAs are a time-consuming optimisation technique. In this paper, we propose to use a naive approach consisting of using samples split by quartile of risk to obtain complete efficient frontiers in a reasonable computation time. Our results show that using reduced problems which only consider a quartile of the assets allow us to explore the efficient frontier for a large range of risk values. In particular, the third quartile allows us to obtain efficie…
Split hand/foot malformation with long-bone deficiency andBHLHA9duplication: report of 13 new families
2013
Split hand/foot malformation (SHFM) with long-bone deficiency (SHFLD, MIM#119100) is a rare condition characterized by SHFM associated with long-bone malformation usually involving the tibia. Previous published data reported several unrelated patients with 17p13.3 duplication and SHFLD. Recently, the minimal critical region had been reduced, suggesting that BHLHA9 copy number gains are associated with this limb defect. Here, we report on 13 new families presenting with ectrodactyly and harboring a BHLHA9 duplication.
Isolated bladder exstrophy associated with a de novo 0.9 Mb microduplication on chromosome 19p13.12
2012
BACKGROUND: The exstrophy-epispadias complex (BEEC) is a urogenital birth defect of varying severity. The causes of the BEEC are likely to be heterogeneous, with individual environmental or genetic risk factors still being largely unknown. In this study, we aimed to identify de novo causative copy number variations (CNVs) that contribute to the BEEC. METHODS: Array-based molecular karyotyping was performed to screen 110 individuals with BEEC. Promising CNVs were tested for de novo occurrence by investigating parental DNAs. Genes located in regions of rearrangements were prioritized through expression analysis in mice to be sequenced in the complete cohort, to identify high-penetrance mutati…
Convergence-based Analysis of Robustness to Delay in Anti-windup Loop of Aircraft Autopilot∗∗This work was supported by Russian Scientific Foundation…
2015
Abstract The windup phenomenon is interpreted as a consequence of the convergent property absence for system with a saturation. This makes it possible to use the frequency-domain criterion for analysis of anti-windup augmentation in the case of stable and marginally stable plants. Based on this approach, robustness of the systems with respect to time delay in the anti-windup loop is examined and the approach for an optimal choice of the static anti-windup gain is proposed. An application of the convergence-based anti-windup control strategy to aircraft flight control for the case of time-delay in the anti-windup loop is described and studied by simulations.