Search results for "DUP"

showing 10 items of 499 documents

Girl With Partial Turner Syndrome and Absence Epilepsy

2007

This report describes a 16-year-old girl with short stature (-5 standard deviations), normal puberty, panic attacks, absence epilepsy, some stigmata of Turner syndrome, and a Madelung deformity. Routine chromosomal analysis revealed a female karyotype with one abnormal chromosome X, with the suspicion of additional material on the short arm. With fluorescent in situ hybridization and array-multiplex amplifiable probe hybridization methodology, a complex aberration was detected, with a deletion of the distal part of Xp22.33 (including the short-stature homeobox gene) and a duplication of Xp22.32-p22.12 proximal to the deleted segment. The deletion in our patient involves the Xp22.33 region. …

Homeodomain ProteinsGeneticsAdolescentTurner SyndromeKaryotypeBiologymedicine.diseaseShort statureEpilepsy AbsenceShort Stature Homeobox ProteinDevelopmental NeuroscienceNeurologyShort Stature Homeobox ProteinPediatrics Perinatology and Child HealthGene duplicationTurner syndromemedicineOMIM : Online Mendelian Inheritance in ManHumansHomeoboxFemaleNeurology (clinical)medicine.symptomX chromosomePediatric Neurology
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Oral CorticoSteroid sparing with biologics in severe asthma: A remark of the Severe Asthma Network in Italy (SANI)

2020

According to the data derived from several national and international registries, including SANI (Severe Asthma Network Italy), and considering the strong impact that frequent or regular use of oral corticosteroid has on quality of life (QoL) of severe asthmatics, as well as on the costs for managing corticosteroid-related diseases, oral corticosteroid sparing up to withdrawal should be considered a primary outcome in the management of severe asthma. New biologics have clearly demonstrated that this effect is possible, with concomitant reduction in the rate of exacerbations and in symptom control. Then, there is no reason for using so frequently oral corticosteroid before having explored al…

ISAR International Severe Asthma RegistrySHARPPediatricsSevere asthmaSA severe asthmaBiologics Oral corticosteroids Real-life Registr Severe asthmaOmalizumabforced expiratory volume in the 1st secondFood &ampGrading of Recommendations Assessmentchronic rhinosinusitis with nasal polyposisFEV1chemistry.chemical_compound0302 clinical medicineQuality of lifeEMAReal WorldEuropean Medicines AgencyBiologics; Oral corticosteroids; Real-life; Registr; Severe asthmaOral corticosteroidsFDA Food & Drug AdministrationImmunology and Allergy030223 otorhinolaryngologySevere Heterogeneous Asthma Research collaborationmusculoskeletal neural and ocular physiologyReal-lifeCRSwNPOCSsBenralizumabDupilumabCRSwNP chronic rhinosinusitis with nasal polyposisGRADESHARP Severe Heterogeneous Asthma Research collaboration Patient-centredSevere Asthma Network in ItalyFDAmedicine.drugPulmonary and Respiratory Medicinelcsh:Immunologic diseases. Allergymedicine.medical_specialtyDrug AdministrationGINA Global Initiative for AsthmaRW Real WorldImmunologymacromolecular substancesRWSettore MED/10 - Malattie Dell'Apparato RespiratorioBiologicsInternational Severe Asthma RegistryISAR03 medical and health sciencesSADisease registrySARP Severe Asthma Research ProgramPatient-centredmedicineAsthmabusiness.industrySettore MED/09 - MEDICINA INTERNASANI Severe Asthma Network in ItalySANIBiological productmedicine.diseaseOCSs Oral CorticoSteroidsGINASARPSevere Asthma Research ProgramFEV1 forced expiratory volume in the 1st second030228 respiratory systemchemistrynervous systemRegistrEMA European Medicines AgencyDevelopment and EvaluationSevere asthma Biologics Oral corticosteroids Real-life Registrbusinesslcsh:RC581-607Global Initiative for AsthmaMepolizumabGRADE Grading of Recommendations Assessment Development and Evaluation
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The nearly Gorenstein property for numerical duplications and semitrivial extensions

2022

In this thesis we present and study the ideal duplication, a new construction within the class of the relative ideals of a numerical semigroup $S$, that, under specific assumptions, produces a relative ideal of the numerical duplication $SJoin^b E$, for some ideal $E$ of $S$. We prove that every relative ideal of the numerical duplication can be uniquely written as the ideal duplication of two relative ideals of $S$; this allows us to better understand how the basic operations of the class of the relative ideals of $SJoin^b E$ work. In particular, we characterize the ideals $E$ such that $SJoin^b E$ is nearly Gorenstein. With the aim to generalize this construction to commutative rings with…

Ideal DuplicationSettore MAT/02 - AlgebraNagata's IdealizationNumerical SemigroupNearly Gorenstein Numerical SemigroupSemitrivial ExtensionNearly Gorenstein RingRelative IdealZ_2-Graded RingCanonical IdealNumerical Duplication
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WITHDRAWN: Systems Biology and Immune Aging

2014

The Publisher regrets that this article is an accidental duplication of anarticle that has already been published, http://dx.doi.org/10.1016/j.imlet.2014.09.009 . The duplicate article has therefore been withdrawn.

Immune systembusiness.industryAccidentalSystems biologyImmunologyGene duplicationImmunology and AllergyMedicineBioinformaticsbusinessImmunology Letters
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Dissecting the factors controlling seed development in the model legume Medicago truncatula

2012

Legumes are not only indispensible for sustainable agriculture but are also a rich source of protein in food and feed for humans and animals, respectively. However, major proteins stored in legume seeds are poor in sulfur-containing amino acids, and may be accompanied by anti-nutritional factors causing low protein digestibility problems. In this regard, Medicago truncatula serves as a model legume to study legume seed development especially the phase of seed storage protein accumulation. As developing legume seeds are complex structures, a thorough knowledge of the morphogenesis of the seed and the characterization of regulatory mechanisms underlying the embryo development and seed filling…

In silicoCytométrie en fluxTransformation génétiqueEndoreduplicationLegumesAuxineFacteur de TranscriptionRemplissage de la graineGenetic transformationIn vitroDOFMedicago truncatulaDéveloppement de la graineAuxin[SDV.BV] Life Sciences [q-bio]/Vegetal BiologyFlow cytometrySeed developmentTranscription factor
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Lengthening the time intervals between doses of dupilumab in remission atopic dermatitis

2023

Infectious Diseasesatopic dermatitis dupilumab therapyDermatology
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A systematic analysis of duplicate records in Scopus

2015

In recent years, the Web of Science Core Collection and Scopus databases have become primary sources for conducting studies that evaluate scientific investigations. Such studies require that duplicate records be excluded to avoid errors of overrepresentation. In this line, we identify duplicate records in Scopus and examine their origins. Identifying journals with duplicate records in Scopus, selecting and downloading bibliographic journal records, and identifying and analyzing the duplicate records is the methodology adopted. Duplicate records are found when articles published in a journal are incorrectly mapped by Scopus to this journal and to a different journal from the same publisher a…

Information retrievalComputer scienceMEDLINEScopusLibrary and Information SciencesComputer Science ApplicationsBibliographic recordDuplicate recordsIndexing errorsScopus databaseBibliographic control guidelinesGeneralLiterature_REFERENCE(e.g.dictionariesencyclopediasglossaries)Bibliometric indicators overdimensionalized
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LightSpMV: Faster CSR-based sparse matrix-vector multiplication on CUDA-enabled GPUs

2015

Compressed sparse row (CSR) is a frequently used format for sparse matrix storage. However, the state-of-the-art CSR-based sparse matrix-vector multiplication (SpMV) implementations on CUDA-enabled GPUs do not exhibit very high efficiency. This has motivated the development of some alternative storage formats for GPU computing. Unfortunately, these alternatives are incompatible with most CPU-centric programs and require dynamic conversion from CSR at runtime, thus incurring significant computational and storage overheads. We present LightSpMV, a novel CUDA-compatible SpMV algorithm using the standard CSR format, which achieves high speed by benefiting from the fine-grained dynamic distribut…

Instruction setCUDASpeedupComputer scienceSparse matrix-vector multiplicationDouble-precision floating-point formatParallel computingGeneral-purpose computing on graphics processing unitsRowSparse matrix2015 IEEE 26th International Conference on Application-specific Systems, Architectures and Processors (ASAP)
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Bit-Parallel Approximate Pattern Matching on the Xeon Phi Coprocessor

2014

Bit-parallel pattern matching encodes calculated values in bit arrays. This approach gains its efficiency by performing multiple updates within a machine word. An important parameter is therefore the machine word size (e.g. 32 or 64 bits). With the increasing length of vector registers, the efficient mapping of bit-parallel pattern matching algorithms onto modern high performance computing architectures is becoming increasingly important. In this paper, we investigate an efficient implementation of the Wu-Manber approximate pattern matching algorithm on the Intel Xeon Phi coprocessor. This architecture features a 512-bit long vector processing unit (VPU) as well as a large number of process…

Instruction setCoprocessorSpeedupComputer scienceParallel computingPattern matchingIntrinsicsWord (computer architecture)Xeon PhiVector processor2014 IEEE 26th International Symposium on Computer Architecture and High Performance Computing
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Exploiting selective instruction reuse and value prediction in a superscalar architecture

2009

In our previously published research we discovered some very difficult to predict branches, called unbiased branches. Since the overall performance of modern processors is seriously affected by misprediction recovery, especially these difficult branches represent a source of important performance penalties. Our statistics show that about 28% of branches are dependent on critical Load instructions. Moreover, 5.61% of branches are unbiased and depend on critical Loads, too. In the same way, about 21% of branches depend on MUL/DIV instructions whereas 3.76% are unbiased and depend on MUL/DIV instructions. These dependences involve high-penalty mispredictions becoming serious performance obstac…

Instructions per cycleSpeedupComputer scienceSpeculative executionSpec#Thread (computing)Parallel computingReuseHardware and ArchitectureSuperscalarHardware_CONTROLSTRUCTURESANDMICROPROGRAMMINGcomputerData cacheSoftwarecomputer.programming_languageJournal of Systems Architecture
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