Search results for "Daily"
showing 10 items of 646 documents
The Impact of Prescribed Dosage Assumptions on the Evaluation of Adherence and Persistence to Medication in Patients After Acute Myocardial Infarction
2021
Medication adherence is a significant problem in public health. Prescription-level pharmacy databases have great potential for monitoring actual drug adherence patterns at the healthcare system level. Many research papers have reported adherence estimates in different settings and populations. However, comparison between studies is not always straightforward due to different approaches taken when computing adherence. A crucial component to accurately estimate adherence is the availability of days’ supply information for each dispensing event. Reasonable assumptions regarding medication dosage have to be made, when this information is not available. In this study, we evaluate adherence and p…
THE OCCURRENCE OF CHROMIUM IN RAW MATERIALS AND ITS FATE IN THE BREWING PROCESS
1987
The chromium content of raw materials, intermediate and final products in the brewing process were determined in order to evaluate the contribution of raw materials to the chromium content of beer. The contribution due to beer in the diet is considered in the light of the recommended daily intake of chromium.
Once-daily QVA149 improves dyspnoea and health status compared with tiotropium plus formoterol in patients without ICS use: A post-hoc analysis of th…
2015
Rationale: The QUANTIFY study compared the approved dual bronchodilator QVA149 with the free-dose combination of tiotropium plus formoterol (TIO+FOR) regarding lung function, dyspnoea and health status in patients with moderate-to-severe COPD. This post-hoc analysis reported on the subgroup of pts without ICS background therapy. Methods: This blinded, triple-dummy 26-week study randomised patients to QVA149 110/50 µg OD or TIO 18 µg OD plus FOR 12 µg b.i.d. (1:1). ICS was allowed as background therapy. Endpoints included lung function (trough FEV1), dyspnoea (TDI) and health status (COPD Assessment Test, CAT). Results: Of the 934 pts randomised (QVA149 [N=476] or TIO+FOR [N=458]); 87.9% com…
Risk assessment and monitoring programme of nitrates through vegetables in the Region of Valencia (Spain)
2017
This study was carried out to determine current levels of nitrate in vegetables marketed in the Region of Valencia (Spain) and to estimate the toxicological risk associated with their intake. A total of 533 samples of seven vegetable species were studied. Nitrate levels were derived from the Valencia Region monitoring programme carried out from 2009 to 2013 and food consumption levels were taken from the first Valencia Food Consumption Survey, conducted in 2010. The exposure was estimated using a probabilistic approach and two scenarios were assumed for left-censored data: the lower-bound scenario, in which unquantified results (below the limit of quantification) were set to zero and the up…
Exploring the relationship between demographic and disease-related variables and perceived effect of health status on sexual activity in patients wit…
2017
To explore the relationship between demographic and disease-related variables and the perceived effect of health status on sexual activity in patients with axial spondyloarthritis (ax-SpA).The study assessed 379 ax-SpA patients consecutively recruited from two rheumatology outpatient clinics. Data collection included information on demographics, markers and measures of ax-SpA disease, treatment, comorbidity, and health-related quality of life (HRQoL) using the Short Form-36. The perceived effect of health status on sexual activity was assessed using question 15 in the HRQoL instrument 15D.The mean age of the patients was 45.6 years, 66.5% were men, 87.3% were human leucocyte antigen-B27 pos…
Cercarial Production of the Trematode Rhipidocotyle fennica in Clams Kept in the Field
1998
The numbers of cercariae that trematodes produce have been previously investigated in the laboratory but not in the field. I studied cercarial production of the bucephalid trematode Rhipidocotyle fennica in the freshwater unionid clam Anodonta piscinalis kept under natural conditions. Naturally infected clams (n = 180) were collected and marked in early June 1996. Every 14 days, starting from the collection date and ending in October, these clams were taken to the laboratory where they were monitored for the emergence of trematode cercariae. Between monitoring dates, the clams were returned to the collection site. From a random subsample of infected clams (n = 12), the number of cercariae p…
Formación del profesorado de Educación Secundaria Obligatoria sobre el Bullying / Teachers training about Bullying at Secondary Education.
2011
We intend to publicize the study conducted in the 2008-2009 academic year on the level of training on skills to confront bulling amongst teachers in Obligatory Secondary Education. These kinds of problems exist throughout the educational system, however, in high school they increase given the characteristics of adolescence. There is a protocol that guides faculty actions when they are faced with bullying situations; however, this does not offer the answers needed for the small, daily incidents that occur in school life. These incidents are disregarded, for they are considered trivial and unimportant. But rather, we should be aware that no harmful act is trivial, especially for those who end…
Variables related to the informal caregivers' burden of dependent senior citizens in Spain
2009
The study aims at analyzing the psychosocial variables associated with the informal caregivers" burden of dependent older people. A sample of 296 dependent people and their informal caregivers (n= 153) was randomly selected among users and non-users of the Spanish public In-Home Help Service (HHS) in an autonomous Spanish region (Comunidad Valenciana). Diverse variables in reference to the care context and the caregiver as well as the care recipient show major associations with the burden: those associated to disease and the social situation of the dependent person, the greater frequency and intensity of care, and the low frequency in which the caregiver receives help from others. The obtai…
Walking Ability and All-Cause Mortality in Older Women
2010
In this study self-reported ability to walk 2 km and six-minute walking test (6MWT) performance were examined as predictors of all-cause mortality in 434 women, aged 63-76 years. The primary outcome measure was all-cause mortality (follow-up: 8 years). Predictors were self-reported difficulties in walking 2 km and 6-min walking distance tertiles of ≤495, 496-560 and ≥561 m, and no test result due to refusal by the physician to grant permission to perform the test or participant's inability or unwillingness to perform the test. During the follow-up, 39 participants died. Participants reporting minor (age- and body mass index-adjusted hazard ratio 2.53, 95% confidence interval 1.12-5.69) or m…
Cross-cultural development and psychometric evaluation of a patient-reported health-related quality of life questionnaire for adults with haemophilia.
2008
Co-morbidities of haemophilia, such as arthropathy and blood-borne infections, can adversely affect the quality of life of adult patients with haemophilia. The purpose of this study was to develop and validate a haemophilia-specific health-related quality of life questionnaire for adults (HAEMO-QoL-A). Subjects with varying severities of haemophilia completed the HAEMO-QoL-A at baseline and 4 weeks. Other assessments included the SF-36 and Health Assessment Questionnaire - Functional Disability Index (HAQ-FDI). Two-hundred and twenty-one participants completed the 41-item HAEMO-QoL-A covering six domains (Physical Functioning, Role Functioning, Worry, Consequences of Bleeding, Emotional Imp…