Search results for "Dam"

Interspecific territoriality in Calopteryx damselflies: the role of secondary sexual characters

2006

Interspecific territoriality is usually interpreted to result from interspecific interference competition, although it may also originate from mistaken species recognition. In the latter case, it may be based on similarity of secondary sexual characters. In the damselfly Calopteryx splendens, males have pigmented wing spots as a sexual character, and males with the largest spots resemble males of another species, Calopteryx virgo. Probably because of this resemblance, C. virgo males are more aggressive towards large- than small-spotted C. splendens males. We examined whether wing spot size of C. splendens males affects territorial interactions between the species. In a removal experiment, t…

Wee1 inhibition potentiates Wip1-dependent p53-negative tumor cell death during chemotherapy

2016

AbstractInactivation of p53 found in more than half of human cancers is often associated with increased tumor resistance to anti-cancer therapy. We have previously shown that overexpression of the phosphatase Wip1 in p53-negative tumors sensitizes them to chemotherapeutic agents, while protecting normal tissues from the side effects of anti-cancer treatment. In this study, we decided to search for kinases that prevent Wip1-mediated sensitization of cancer cells, thereby interfering with efficacy of genotoxic anti-cancer drugs. To this end, we performed a flow cytometry-based screening in order to identify kinases that regulated the levels of γH2AX, which were used as readout. Another criter…

Real-time hermeneutics : meaning-making in ludonarrative digital games

2015

Experiencia y verdad en la hermenéutica de Gadamer. Algunos problemas

2006

Gadamer vincula su concepción de la experiencia hermenéutica a una interpretación especulativa de la verdad que no se justifica simplemente por la exigencia de superar el enfoque metódico. Este ensayo responde al propósito de indagar hasta qué punto esta interpretación sólo supera la escisión fenomenológica entre conciencia y objeto en tanto que remite a un fundamento ontológico de su unidad, que pasa a ocupar la posición de sujeto. Nuestra hipótesis es que el concepto gadameriano de la verdad como una «infinitud de sentido» genera tensiones con su concepción de la experiencia hermenéutica, que permanecen irresueltas. También intentaremos mostrar que una de las consecuencias que se siguen d…

Exact 3D solution for static and damped harmonic response of simply supported general laminates

2014

International audience; The state-space method is adapted to obtain three dimensional exact solutions for the static and damped dynamic behaviors of simply supported general laminates. The state-space method is written in a general form that permits to handle both cross-ply and antisymmetric angle-ply laminates. This general form also permits to obtain exact solutions for general laminates, albeit with some constraints. For the general case and for the static behavior, either an additive term is added to the load to simulate simply supported boundary conditions, or the plate bends in a particular way. For the dynamic behavior, the general case leads to pairs of natural frequencies for each …

Optimal passive-damping design using a decentralized velocity-feedback H-infinity approach

2012

In this work, a new strategy to design passive energy dissipation systems for vibration control of large structures is presented. The method is based on the equivalence between passive damping systems and fully decentralized static velocity-feedback controllers. This equivalence allows to take advantage of recent developments in static output-feedback control design to formulate the passive-damping design as a single optimization problem with Linear Matrix Inequality constraints. To illustrate the application of the proposed methodology, a passive damping system is designed for the seismic protection of a five-story building with excellent results. Peer Reviewed

Process intensification in a photocatalytic membrane reactor: Analysis of the techniques to integrate reaction and separation

2017

Abstract Different methods to integrate reaction and separation in a membrane reactor are studied in the present work, with the aim being to highlight the pros and cons of the different alternatives and the effects of the intervening parameters. The coupling of the two processes can take place inside a single apparatus or using separate units. If a single apparatus is utilized, the coupling is more direct, but separate units offer higher degrees of freedom for the design with more opportunities to optimize the system without constraints. However, when using separate units, the integration of the two unit operations depends largely on the parameters intervening in the coupling procedure. The…

A thermodynamically consistent cohesive-frictional interface model for mixed mode delamination

2016

Abstract A new interface constitutive model based on damage mechanics and frictional plasticity is presented. The model is thermodynamically consistent, it is able to accurately reproduce arbitrary mixed mode debonding conditions and it is proved that the separation work is always bounded between the fracture energy in mode I and the fracture energy in mode II. Analytical results are given for proportional loading paths and for two non-proportional loading paths, confirming the correct behavior of the model for complex loading histories. Numerical and analytical solutions are compared for three classical delamination tests and frictional effects on 4ENF are also considered.

The interphase model applied to the analysis of masonry structures

2014

Abstract Masonry material presents a mechanical response strongly dependent on the static and kinematic phenomena occurring in the constituents and at their joints. At the mesoscopic level the interaction between the units is simulated by means of specific mechanical devices such as the zero thickness interface model where the contact tractions and the displacement discontinuities are the primary static and kinematic variables respectively. In many cases the joint response depends also on internal stresses and strains within the interface layer adjacent to the joint interfaces. The introduction of internal stresses and strains leads to the formulation of the interphase model, a sort of enha…

Characteristics of new patient referrals to specialised diabetic foot units across Europe and factors influencing delays

2021

Objective: Foot ulcers are a common complication of diabetes and are associated with an increase in lower limb amputation and death. Early referral to a specialised unit is recommended. The aim of this study was to assess the characteristics of new-patient referrals to specialised diabetes foot care units across Europe and to determine the factors involved in delayed referral. Method: In this prospective observational study, consecutive patients with a new foot ulcer presenting to nine diabetic foot centres in five European countries (France, Germany, Italy, Spain and the UK) were included. Results: Some 25% of the 332 patients included had presented with a foot ulcer >3 months before re…