Search results for "Dam"
showing 10 items of 3828 documents
Rac1 protein signaling is required for DNA damage response stimulated by topoisomerase II poisons.
2012
To investigate the potency of the topoisomerase II (topo II) poisons doxorubicin and etoposide to stimulate the DNA damage response (DDR), S139 phosphorylation of histone H2AX (γH2AX) was analyzed using rat cardiomyoblast cells (H9c2). Etoposide caused a dose-dependent increase in the γH2AX level as shown by Western blotting. By contrast, the doxorubicin response was bell-shaped with high doses failing to increase H2AX phosphorylation. Identical results were obtained by immunohistochemical analysis of γH2AX focus formation, comet assay-based DNA strand break analysis, and measuring the formation of the topo II-DNA cleavable complex. At low dose, doxorubicin activated ataxia telangiectasia m…
RADIATION CURING OF CARBON FIBRE COMPOSITES
2012
Radiation processing: a versatile methodology to tune the structure of polymeric materials
2013
IAEA Contribution to Nanosized Targeted Radiopharmaceuticals for Drug Delivery.
2022
The rapidly growing interest in the application of nanoscience in the future design of radiopharmaceuticals and the development of nanosized radiopharmaceuticals in the late 2000′s, resulted in the creation of a Coordinated Research Project (CRP) by the International Atomic Energy Agency (IAEA) in 2014. This CRP entitled ‘Nanosized delivery systems for radiopharmaceuticals’ involved a team of expert scientist from various member states. This team of scientists worked on a number of cutting-edge areas of nanoscience with a focus on developing well-defined, highly effective and site-specific delivery systems of radiopharmaceuticals. Specifically, focus areas of various teams of scientists com…
Rappresentanza diretta ed indiretta: un cantiere ancora aperto
2012
L'autore propone una rivisitazione del dibattito interno in tema di rappresentanza indiretta, muovendo dalla posizione espressa dalle Sezioni Unite, alla luce degli spunti che possono trarsi dalla prospettiva europea. dell'istituto. Il modello di rappresentanza emergente dalla prospettiva europea sembra confermare gli sviluppi del diritto vivente interno. Si prospetta il superamento della contrapposizione tra rappresentanza diretta e rappresentanza indiretta, attraverso il superamento della c.d contemplatio domini e la valorizzazione del criterio dell'affidamento. La rappresentanza, nella prospettiva europea, sembra potersi ricostruire intorno al criterio dell'affidamento, quale principale …
Achilles tendon viscoelastic properties and mechanical responses to a single bout of exercise
2014
Quando le garanzie cedono all'ideologia: il diritto penale inquinato dalla legislazione razziale fascista
2021
Furthermore, Fascism produces deep wounds in the development of criminal law. The introduction of the racial corpus becomes a Trojan horse capable of breaching all guarantees. Clear data emerges: the persecution of the Jews takes place primarily outside the parameters of criminal law, but the normatives in defense of the lineage will actually favor racial laws. Mirroring the formal permanence system of liberal guarantees is a stance taken by many criminal lawyers who, in some cases, seem to take a different position than those imposed by the regime, but only in legal journals circulating in the academic field and without any impactful influence on political decisions. There are at least thr…
recensione a F. Frontisi-Ducroux, Ouvrages des dames. Ariane, Hélène, Pénélope..., Paris, Editions du Seuil, 2009
2010
Recensione al volume di cui si evidenziano le linee tematiche e le chiavi interpretative
Intérêts et limites de l’electrostimulation pour l’évaluation, le traitement et la prévention des altérations neuromusculaires induites par l’exercic…
2004
L'objectif de ce travail était d'une part d'étudier les altérations neuromusculaires induites par un exercice excentrique sollicitant les muscles extenseurs du genou, et d'autre part d'étudier l'efficacité de l'électrostimulation (ES) comme moyen d'évaluation, de traitement et de prévention de ces altérations. La première étude de ce travail consistait à évaluer les contributions des mécanismes centraux et périphériques à la diminution de la contraction maximale volontaire observée après l'exercice excentrique. La fatigue basse fréquence (FBF) et la fatigue centrale expliquaient principalement la diminution du moment maximal volontaire après l'exercice excentrique. Le but de la deuxième étu…
Acute and chronic effects of cold treatment on physiological variables and neuromuscular function during a short training period in men
2015
Introduction. Recovery following various physical exercises is a complicated process. The exercise session can involve strong demands on both muscle structure and energy production (aerobic and anaerobic). Many exercise sessions also induce muscle damage (exercise induced muscle damage; EIMD). Different recovery methods attempt to alleviate or prevent EIMD and its associated symptoms, such as muscle soreness and swelling, and reduction in muscle function. One of the used strategies is cold treatment (cryotherapy), which decreases tissue temperature and subsequently effects on e.g. blood flow, metabolism and neural conductance velocity. To date, there is conflicting evidence to support the u…