Search results for "Data Analysis"
showing 10 items of 383 documents
Harmonizing behavioral outcomes across studies, raters, and countries: application to the genetic analysis of aggression in the ACTION Consortium
2020
BACKGROUND: Aggression in children has genetic and environmental causes. Studies of aggression can pool existing datasets to include more complex models of social effects. Such analyses require large datasets with harmonized outcome measures. Here, we made use of a reference panel for phenotype data to harmonize multiple aggression measures in school-aged children to jointly analyze data from five large twin cohorts.METHODS: Individual level aggression data on 86,559 children (42,468 twin pairs) were available in five European twin cohorts measured by different instruments. A phenotypic reference panel was collected which enabled a model-based phenotype harmonization approach. A bi-factor i…
Normalizing temporal patterns to analyze sit-to-stand movements by using registration of functional data
2004
Functional data analysis techniques provide an alternative way of representing movement and movement variability as a function of time. In particular, the registration of functional data provides a local normalization of time functions. This normalization transforms a set of curves, records of repeated trials, yielding a new set of curves that only vary in terms of amplitude. Therefore, main events occur at the "same time" for all transformed curves and interesting features of individual recordings remain after averaging processes. This paper presents an application of the registration process to the analysis of the vertical forces exerted on the ground by both feet during the sit-to-stand …
Construct validity of the anxiety sensitivity index-3 in clinical samples
2012
"Using two clinical samples of patients, the presented studies examined the construct validity of the recently revised Anxiety Sensitivity Index-3 (ASI-3). Confirmatory factor analyses established a clear three-factor structure that corresponds to the postulated subdivision of the construct into correlated somatic, social, and cognitive components. Participants with different primary clinical diagnoses differed from each other on the ASI-3 subscales in theoretically meaningful ways. Specifically, the ASI-3 successfully discriminated patients with anxiety disorders from patients with nonanxiety disorders. Moreover, patients with panic disorder or agoraphobia manifested more somatic concerns …
Data analytics in banks' audit: The case of loan loss provisions in Uruguay
2016
Abstract The purpose of this study is two-fold: firstly, to analyze the benefits of implementing an enterprise resource planning (ERP) system and using eXtensible Business Reporting Language (XBRL) format to report in the banking industry considering the industry's specific risks and complexities. Secondly, to show that both, ERP and XBRL are necessary to successfully use Computer Assisted Audit Techniques (CAATs) while performing audit procedures to verify the compliance of certain crucial regulatory requirements. The study shows the possible consequences of not using CAATs to audit the compliance of loan loss provisions' regulatory requirements in Uruguay.
Scatter tabu search for multiobjective clustering problems
2011
We propose a hybrid heuristic procedure based on scatter search and tabu search for the problem of clustering objects to optimize multiple criteria. Our goal is to search for good approximations of the efficient frontier for this class of problems and provide a means for improving decision making in multiple application areas. Our procedure can be viewed as an extension of SSPMO (a scatter search application to nonlinear multiobjective optimization) to which we add new elements and strategies specially suited for combinatorial optimization problems. Clustering problems have been the subject of numerous studies; however, most of the work has focused on single-objective problems. Clustering u…
Functional Data Analysis for Optimizing Strategies of Cash-Flow Management
2017
The cash management deals with problem of automating and managing cash-flow processes. Optimization of the management processes greatly reduces overall cash handling costs. The present analysis is an empirical study of cash flows, from and to bank branches, deriving an underlying theoretical framework, which can in a reasonable way be connected with the optimal strategy. Functional data analysis is considered an appropriate framework to analyze the dynamics of the time series behavior of cash flows: since the observations are not equally spaced in time and their number is different for each series, they are converted into a collection of random curves in a space spanned by finite dimensiona…
Zeeman effect in sulfur monoxide: A tool to probe magnetic fields in star forming regions
2017
[Context] Magnetic fields play a fundamental role in star formation processes and the best method to evaluate their intensity is to measure the Zeeman effect of atomic and molecular lines. However, a direct measurement of the Zeeman spectral pattern from interstellar molecular species is challenging due to the high sensitivity and high spectral resolution required. So far, the Zeeman effect has been detected unambiguously in star forming regions for very few non-masing species, such as OH and CN.
Functional Data Analysis for Gait Analysis after Stroke
2013
Variability is one of the key determinants of gait after stroke. Functional Data Analysis (FDA) is a suitable tool to deal with variability associated with movement analysis patterns. In this contribution (FDA) has been applied for the analysis 53 post-stroke patients. Functional Principal Components Analysis (FPCA) has been applied. Dependence of velocity on the functional state of the patient has been found as well as other mechanisms that are hidden in conventional parametric analysis of the curves.
Studying Nucleosomes Positioning by a Multi-Layer Model
2007
Eukaryotic DNA is packaged into a highly compact and dynamic structure called chromatin. While this packaging allows the cell to organize a large and complex genome in the nucleus, it can also block the access of transcription factors and other proteins to DNA. Nucleosomes are the fundamental repeating units of eukaryotic chromatin. Nucleosome position can be regulated in vivo by multi-subunit chromatin remodeling complexes, and their position can influence gene expression in eukaryotic cells. Alterations in chromatin structure, and hence in nucleosome organization, can result in a variety of diseases, including cancer, highlighting the need to achieve a better understanding of the molecula…
The Acts project: track reconstruction software for HL-LHC and beyond
2019
The reconstruction of trajectories of the charged particles in the tracking detectors of high energy physics experiments is one of the most difficult and complex tasks of event reconstruction at particle colliders. As pattern recognition algorithms exhibit combinatorial scaling to high track multiplicities, they become the largest contributor to the CPU consumption within event reconstruction, particularly at current and future hadron colliders such as the LHC, HL-LHC and FCC-hh. Current algorithms provide an extremely high standard of physics and computing performance and have been tested on billions of simulated and recorded data events. However, most algorithms were first written 20 year…