Search results for "Data"

showing 10 items of 12992 documents

Improved T2* assessment in liver iron overload by magnetic resonance imaging.

2009

In the clinical MRI practice, it is common to assess liver iron overload by T2* multi-echo gradient-echo images. However, there is no full consensus about the best image analysis approach for the T2* measurements. The currently used methods involve manual drawing of a region of interest (ROI) within MR images of the liver. Evaluation of a representative liver T2* value is done by fitting an appropriate model to the signal decay within the ROIs vs. the echo time. The resulting T2* value may depend on both ROI placement and choice of the signal decay model. The aim of this study was to understand how the choice of the analysis methodology may affect the accuracy of T2* measurements. A softwar…

AdultMaleIron OverloadBiomedical EngineeringBiophysicsImage processingSignalSoftwareRegion of interestImage Processing Computer-AssistedMedicineLiver ironHumansRadiology Nuclear Medicine and imagingliver iron overloadObserver VariationReproducibilitymedicine.diagnostic_testbusiness.industrybeta-ThalassemiaReproducibility of ResultsPattern recognitionMagnetic resonance imagingMagnetic Resonance ImagingLiverData Interpretation StatisticalAutomatic segmentationFemaleArtificial intelligencebusinessNuclear medicineAlgorithmsSoftwareMagnetic resonance imaging
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Planning an action.

1997

The motor control of a sequence of two motor acts forming an action was studied in the present experiment. The two analysed motor acts were reaching-grasping an object (first target) and placing it on a second target of the same shape and size (experiment 1). The aim was to determine whether extrinsic properties of the second target (i.e. target distance) could selectively influence the kinematics of reaching and grasping. Distance, position and size of both targets were randomly varied across the experimental session. The kinematics of the initial phase of the first motor act, that is, velocity of reaching and hand shaping of grasping, were influenced by distance of the second target. No k…

AdultMaleKinematicsComputer scienceMovementPoison controlKinematicsStimulus (physiology)Visual controlFingersMental ProcessesHumansComputer visionMotor actCommunicationLift (data mining)business.industryGeneral NeuroscienceGRASPReaching-graspingMotor controlBody movementWristHandPlacingThumbArmFemaleArtificial intelligencebusinessPsychomotor PerformanceExperimental brain research
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Isolated hevein-like domains, but not 31-kd endochitinases, are responsible for IgE-mediated in vitro and in vivo reactions in latex-fruit syndrome.

2005

Background Individuals with natural rubber latex allergy often have immediate reactions to plant-derived foods and fresh fruits, such as avocado and banana. IgE of these patients has been shown to bind endochitinases containing an N-terminal hevein-like domain (HLD). However, evidence on 31-kd endochitinase-induced reactions in vivo is lacking. Objective We sought to assess the clinical significance of 31-kd endochitinases and isolated HLDs in latex-fruit syndrome. Methods The 31-kd endochitinases and corresponding HLDs were purified or produced from avocado, banana, latex, and wheat germ. Skin prick test reactivities against purified proteins were examined in 15 patients with natural rubbe…

AdultMaleLatexImmunologyMolecular Sequence DataEnzyme-Linked Immunosorbent Assaymedicine.disease_causeImmunoglobulin ECross-reactivityMicrobiology03 medical and health sciences0302 clinical medicineFood allergyChitin bindingLatex HypersensitivitymedicineImmunology and AllergyHumansAmino Acid Sequence030304 developmental biologyDNA PrimersSkin Tests0303 health sciencesbiologySequence Homology Amino AcidChemistryPerseaChitinasesfood and beveragesMusaAllergensImmunoglobulin EMiddle Agedmedicine.diseaseIn vitroWheat germ agglutinin3. Good healthProtein Structure Tertiary030228 respiratory systemSpectrometry Mass Matrix-Assisted Laser Desorption-IonizationImmunologybiology.proteinFemaleAntibodyPlant LectinsAnaphylaxisFood HypersensitivityAntimicrobial Cationic PeptidesThe Journal of allergy and clinical immunology
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Muscle tone in different joint positions and at submaximal isometric torque levels

2007

The aim was to evaluate the tone and electric activity of the quadriceps muscle at rest and different torque levels. The second aim was to study whether thickness of soft tissues and change in the joint position would affect muscle tone. Eighteen healthy subjects participated. Computerized muscle tonometer (CMT) and surface electromyography (sEMG) measurements were performed: seated, first at rest with leg straight and then with the knee at 60 degrees . Thereafter measurements were obtained at levels of 80, 60, 40 and 20% of the maximum isometric torque at the same knee angle. Thickness of skin, subcutis and muscle was measured by ultrasound. The CMT values taken were the depth the indenter…

AdultMaleManometryPhysiologyBiomedical EngineeringBiophysicsElectromyographyTone (musical instrument)Muscle toneIsometric ContractionPhysiology (medical)medicineHumansTorqueMuscle Skeletalmedicine.diagnostic_testElectromyographybusiness.industryUltrasoundWork (physics)Soft tissueRepeatabilityAnatomyBiomechanical PhenomenaElectrophysiologyCross-Sectional Studiesmedicine.anatomical_structureData Interpretation StatisticalMuscle TonusFemaleJointsbusinessBiomedical engineeringPhysiological Measurement
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Incidence of cardiovascular events and risk markers in a prospective study of children diagnosed with Marfan syndrome

2018

Little is known about the incidence of cardiovascular events (CVEs) and their associated risk markers in children with Marfan syndrome (MFS).To assess the incidence of CVEs and determine risk markers in a cohort diagnosed with Marfan syndrome during childhood and followed for several years.From a French multicentre nationwide database, 462 patients with MFS diagnosed during childhood were included prospectively. Patients' files were screened for a period of 20 years (1993-2013). CVEs (e.g. death, aortic dissection, cardiac valve or aortic root surgery) were assessed during the prospective follow-up.Median (interquartile range) age at the end of follow-up was 17.2 (11.1-21.3) years. CVEs wer…

AdultMaleMarfan syndromePediatricsmedicine.medical_specialtyTime FactorsAdolescentDatabases Factual030204 cardiovascular system & hematologyRisk AssessmentMarfan SyndromeYoung Adult03 medical and health sciences0302 clinical medicineRisk FactorsInterquartile rangeCardiac valvemedicineHumansProspective Studies030212 general & internal medicineChildProspective cohort studyAortic dissectionbusiness.industryIncidenceIncidence (epidemiology)Age FactorsInfantGeneral MedicinePrognosismedicine.diseaseConfidence intervalCardiovascular DiseasesChild PreschoolCohortFemaleFranceCardiology and Cardiovascular MedicinebusinessArchives of Cardiovascular Diseases
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Neuromuscular responses to different resistance loading protocols using pneumatic and weight stack devices

2013

The purpose of this study was to examine single repetition characteristics and acute neuromuscular responses to typical hypertrophic (HL), maximal strength (MSL), and power (PL) loadings performed with two of the most common resistance modes; pneumatic and weight stack. Acute responses were assessed by measuring maximal voluntary contraction (MVC), corresponding quadriceps-EMG and resting and superimposed twitch torques. Activation level was calculated from the twitch torques. Decreases in MVC were greater during HL and MSL than during PL. During HL, resting twitch force decreased 8% (P < 0.05) more on the weight stack than on the pneumatic device. Furthermore, loading using the weight stac…

AdultMaleMaterials sciencePhysical ExertionBiophysicsNeuroscience (miscellaneous)Young AdultVoluntary contractionStack (abstract data type)Maximal strengthmedicineHumansContraction velocityTwitch forceMuscle SkeletalMuscle fatigueResistance trainingResistance TrainingTorquePhysical FitnessMuscle FatiguePhysical EnduranceNeurology (clinical)medicine.symptomMuscle ContractionBiomedical engineeringMuscle contractionJournal of Electromyography and Kinesiology
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Influence of Beach Chair Position on Cerebral Oxygen Saturation

2013

Although beach chair position (BCP) is frequently used for shoulder surgery, a potentially detrimental influence on cerebral oxygenation is discussed. Therefore, the present study investigated changes in regional cerebral oxygen saturation (rSO2/StO2) during BCP comparing 2 different devices for near-infrared spectroscopy measurement.Data were collected in 35 patients undergoing shoulder surgery in BCP and compared with a control group of 35 awake volunteers. The rSO2/StO2 was assessed using INVOS and FORE-SIGHT monitors. Mean arterial blood pressure (MAP), peripheral oxygen saturation (SpO2), PeCO2, FiO2, end-tidal sevoflurane concentration, and rSO2/StO2 were measured before positioning, …

AdultMaleMethyl EthersBeach chair positionSupine positionAdolescentShoulder surgerymedicine.medical_treatmentCerebral oxygen saturationPatient PositioningSevofluraneYoung AdultOxygen ConsumptionCerebral oxygenationHeart RateSupine PositionmedicineHumansArterial PressureOximetryCerebral oximetryAgedbusiness.industryData interpretationMiddle AgedOxygenAnesthesiology and Pain MedicineData Interpretation StatisticalAnesthesiaAnesthetics InhalationFemaleSurgeryNeurology (clinical)Anesthesia Inhalationbusinesshuman activitiesJournal of Neurosurgical Anesthesiology
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Identification of a Unique Helicobacter Species by 16S rRNA Gene Analysis in an Abdominal Abscess from a Patient with X-Linked Hypogammaglobulinemia

2000

ABSTRACT A unique Helicobacter species, MZ640285, was isolated from a patient with X-linked hypogammaglobulinemia suffering from recurrent abdominal abscesses and was identified by 16S rRNA gene sequence analysis. In the phylogenetic tree, the isolate fell into a cluster which included Flexispira rappini , Helicobacter bilis , and Helicobacter sp. strain Mainz. Helicobacters are being increasingly recognized as pathogens in immunocompromised hosts. These fastidious bacteria are not easily cultured in the routine diagnostic laboratory, and this is the first report of their identification by 16S rRNA gene sequencing performed directly from a clinical specimen.

AdultMaleMicrobiology (medical)Fastidious organismHelicobacter bilisAbdominal AbscessX ChromosomeGenetic LinkageMolecular Sequence DataBiologyPolymerase Chain ReactionHelicobacter InfectionsHypogammaglobulinemiaImmunocompromised HostAgammaglobulinemiaRecurrenceHelicobacterRNA Ribosomal 16SmedicineHumansHelicobacterRibosomal DNAPhylogenetic treeGenes rRNABacteriologySequence Analysis DNARibosomal RNA16S ribosomal RNAmedicine.diseasebiology.organism_classificationVirologyJournal of Clinical Microbiology
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Helicobacter sp. strain Mainz isolated from an AIDS patient with septic arthritis: case report and nonradioactive analysis of 16S rRNA sequence

1994

A campylobacter-like organism was isolated from an effusion of the left knee joint of an AIDS patient 2 weeks after bacteremia with a morphologically identical organism. Amplified genomic 16S rRNA sequences were analyzed by a nonradioactive blotting technique. The closest match was found with Helicobacter fenelliae (97.7% homology). Sequence data and phenotype suggest that the isolate may represent a so far unrecognized species of the genus Helicobacter.

AdultMaleMicrobiology (medical)Knee JointMolecular Sequence DataBiologyHelicobacter InfectionsHelicobacterRNA Ribosomal 16SGenotypemedicineHumansTypingHelicobacterRibosomal DNAAcquired Immunodeficiency SyndromeArthritis InfectiousBase SequenceSequence Analysis RNAbiology.organism_classificationmedicine.disease16S ribosomal RNAVirologyPhenotypeBacteremiaSeptic arthritisResearch ArticleJournal of Clinical Microbiology
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Presence of Rickettsia conorii subsp. israelensis , the Causative Agent of Israeli Spotted Fever, in Sicily, Italy, Ascertained in a Retrospective St…

2005

ABSTRACT A retrospective analysis by molecular-sequence-based techniques was performed to correctly identify the etiological agent of 24 Mediterranean spotted fever cases occurring in Western Sicily, Italy, from 1987 to 2001. Restriction analysis of a 632-bp PCR-amplified portion of the ompA gene allowed presumptive identification of five clinical isolates as belonging to Rickettsia conorii subsp. israelensis , the etiological agent of Israeli spotted fever (ISF). The remaining 19 rickettsial isolates were Rickettsia conorii subsp. conorii , the only pathogenic rickettsia of the spotted fever group reported in Italy until the present. Sequence analysis of the ompA gene confirmed the identif…

AdultMaleMicrobiology (medical)Settore MED/07 - Microbiologia E Microbiologia ClinicaChlamydiology and RickettsiologyMolecular Sequence DataBiologyBoutonneuse FeverRickettsiaceaeMicrobiologymedicineHumansIsraelAgedRetrospective StudiesRetrospective cohort studySequence Analysis DNAMiddle Agedmedicine.diseasebiology.organism_classificationVirologySpotted feverBoutonneuse feverRickettsia conoriiRickettsiosisRickettsiaItalyBacteria (microorganisms) Rickettsia Rickettsia conoriibacteriaFemaleRickettsia conoriiRickettsialesBacterial Outer Membrane ProteinsJournal of Clinical Microbiology
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