Search results for "Database"

showing 10 items of 2136 documents

Psychiatric genome-wide association study analyses implicate neuronal, immune and histone pathways

2015

G.B. and S.N. acknowledge funding support for this work from the National Institute for Health Research (NIHR) Mental Health Biomedical Research Centre at South London and Maudsley NHS Foundation Trust and King's College London. P.H.L. is supported by US National Institute of Mental Health (NIMH) grant K99MH101367. Genome-wide association studies (GWAS) of psychiatric disorders have identified multiple genetic associations with such disorders, but better methods are needed to derive the underlying biological mechanisms that these signals indicate. We sought to identify biological pathways in GWAS data from over 60,000 participants from the Psychiatric Genomics Consortium. We developed an an…

Netherlands Twin Register (NTR)Statistical methodsAutismMedizinLOCIGenome-wide association studyheritabilityGenome-wide association studiesHistonesGenètica mèdica0302 clinical medicineHistone methylationDatabases Genetic2.1 Biological and endogenous factorsPsychologyGWASAetiologyPsychiatric geneticsR2Cbipolar disorderPsychiatry0303 health sciencesDisordersLociDepressionGeneral NeuroscienceMental DisordersMedical geneticsMETHYLATIONBrain3rd-DASSerious Mental IllnessPsychiatric Disorders3. Good healthHistoneMental HealthSchizophreniaMental DisorderCognitive Sciences[SDV.NEU]Life Sciences [q-bio]/Neurons and Cognition [q-bio.NC]PromotersBDCBURDENRC0321 Neuroscience. Biological psychiatry. NeuropsychiatryHumanSignal Transductionmedicine.medical_specialtyDISORDERSGenomicsNetwork and Pathway Analysis Subgroup of Psychiatric Genomics ConsortiumBurdenBiologyMethylationArticleBiological pathwayPROMOTERS03 medical and health sciencesDatabasesGeneticmedicineGenetics/dk/atira/pure/keywords/cohort_studies/netherlands_twin_register_ntr_HumansGenetic Predisposition to Diseasehistone methylationBipolar disorderPsiquiatriaAUTISMPsychiatry030304 developmental biologyGenetic associationNeurodevelopmental disorders Donders Center for Medical Neuroscience [Radboudumc 7]Neurology & NeurosurgeryNeuroscience (all)Human GenomeNeurosciencesmedicine.diseaseBrain DisordersGood Health and Well BeingDE-NOVO MUTATIONSPerturbações do Desenvolvimento Infantil e Saúde MentalRC0321SchizophreniaGenome-wide Association StudiesDe-novo mutationsmajor depressionNeuroscience030217 neurology & neurosurgeryGenome-Wide Association Study
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SymbioGenomesDB: a database for the integration and access to knowledge on host-symbiont relationships.

2014

Symbiotic relationships occur naturally throughout the tree of life, either in a commensal, mutualistic or pathogenic manner. The genomes of multiple organisms involved in symbiosis are rapidly being sequenced and becoming available, especially those from the microbial world. Currently, there are numerous databases that offer information on specific organisms or models, but none offer a global understanding on relationships between organisms, their interactions and capabilities within their niche, as well as their role as part of a system, in this case, their role in symbiosis. We have developed the SymbioGenomesDB as a community database resource for laboratories which intend to investigat…

NicheTree of lifeGenomicsBiologycomputer.software_genreGenomeGeneral Biochemistry Genetics and Molecular BiologyHost-Parasite InteractionsUser-Computer InterfaceDatabases GeneticAnimalsHumansSymbiosisInternetGenomeDatabasebusiness.industryMetadataDatabase ToolGenesScripting languageTable (database)The InternetGeneral Agricultural and Biological SciencesbusinesscomputerInformation SystemsDatabase : the journal of biological databases and curation
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NATURAL SELECTION AND THE ORGAN-SPECIFIC DIFFERENTIATION OF HIV-1 V3 HYPERVARIABLE REGION

2004

The existence of organ-specific HIV-1 populations within infected hosts has been studied for many years; nonetheless results reported by different authors are somewhat discrepant. To tackle this problem, we used a population genetics approach to analyze previously published data from the V3 hypervariable region of the envelope env gene. Our results are compatible with a population subdivision by organs in 95% of individuals analyzed at autopsy. In addition, populations infecting the nervous system and testicles clearly appear as differentiated subsets of the so-called macrophage-tropic variants. Liver and kidney may harbor differentiated populations as well. Although it is widely accepted t…

Nonsynonymous substitutionPopulationPopulation geneticsHIV Envelope Protein gp120BiologyEvolution MolecularGeneticsCluster AnalysisHumansSelection GeneticeducationEcology Evolution Behavior and SystematicsGeneticsAnalysis of VarianceLikelihood Functionseducation.field_of_studyNatural selectionBase SequenceModels GeneticMechanism (biology)HIVPeptide FragmentsHypervariable regionGenetics PopulationOrgan SpecificityViral evolutionAdaptationDatabases Nucleic AcidGeneral Agricultural and Biological SciencesSequence AlignmentEvolution
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SEARCHES FOR POINT-LIKE AND EXTENDED NEUTRINO SOURCES CLOSE TO THE GALACTIC CENTER USING THE ANTARES NEUTRINO TELESCOPE

2014

A search for cosmic neutrino sources using six years of data collected by the ANTARES neutrino telescope has been performed. Clusters of muon neutrinos over the expected atmospheric background have been looked for. No clear signal has been found. The most signal-like accumulation of events is located at equatorial coordinates R.A. = -46º.8 and decl. = -64º.9 and corresponds to a 2.2 sigma background fluctuation. In addition, upper limits on the flux normalization of an E-2 muon neutrino energy spectrum have been set for 50 pre-selected astrophysical objects. Finally, motivated by an accumulation of seven events relatively close to the Galactic Center in the recently reported neutrino sample…

Normalization (statistics)AstrofísicaParticle physics[PHYS.ASTR.HE]Physics [physics]/Astrophysics [astro-ph]/High Energy Astrophysical Phenomena [astro-ph.HE][PHYS.ASTR.IM]Physics [physics]/Astrophysics [astro-ph]/Instrumentation and Methods for Astrophysic [astro-ph.IM]Physics::Instrumentation and DetectorsAstrophysics::High Energy Astrophysical PhenomenaFOS: Physical sciencesFluxAstrophysicslaw.inventionHigh Energy Physics - ExperimentTelescopeHigh Energy Physics - Experiment (hep-ex)neutrinolaw[PHYS.HEXP]Physics [physics]/High Energy Physics - Experiment [hep-ex]Point (geometry)Muon neutrinoNeutrinsNeutrinosInstrumentation and Methods for Astrophysics (astro-ph.IM)High Energy Astrophysical Phenomena (astro-ph.HE)PhysicsMuonCOSMIC cancer databaseGalaxy: center[SDU.ASTR.HE]Sciences of the Universe [physics]/Astrophysics [astro-ph]/High Energy Astrophysical Phenomena [astro-ph.HE]astroparticle physicFísicaneutrinosAstronomy and Astrophysicscenter [Galaxy]Galaxy centerNeutrino astrophysics[SDU.ASTR.IM]Sciences of the Universe [physics]/Astrophysics [astro-ph]/Instrumentation and Methods for Astrophysic [astro-ph.IM]13. Climate actionSpace and Planetary Scienceastroparticle physicsFISICA APLICADA:Física::Astronomia i astrofísica [Àrees temàtiques de la UPC]High Energy Physics::ExperimentNeutrinoAstroparticle physicsMATEMATICA APLICADAAstrophysics - High Energy Astrophysical PhenomenaAstrophysics - Instrumentation and Methods for Astrophysicsastroparticle physics; Galaxy: center; neutrinos
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Combining Inter-Subject Modeling with a Subject-Based Data Transformation to Improve Affect Recognition from EEG Signals

2019

Existing correlations between features extracted from Electroencephalography (EEG) signals and emotional aspects have motivated the development of a diversity of EEG-based affect detection methods. Both intra-subject and inter-subject approaches have been used in this context. Intra-subject approaches generally suffer from the small sample problem, and require the collection of exhaustive data for each new user before the detection system is usable. On the contrary, inter-subject models do not account for the personality and physiological influence of how the individual is feeling and expressing emotions. In this paper, we analyze both modeling approaches, using three public repositories. T…

Normalization (statistics)Data AnalysisSupport Vector MachineDatabases FactualComputer sciencemedia_common.quotation_subjectEmotionsData transformation (statistics)Context (language use)02 engineering and technologyvalence detectionElectroencephalographyAffect (psychology)Machine learningcomputer.software_genrelcsh:Chemical technologyBiochemistryModels BiologicalArticleAnalytical Chemistrydata transformation0202 electrical engineering electronic engineering information engineeringmedicinePersonalityHumanslcsh:TP1-1185EEGElectrical and Electronic EngineeringInstrumentationarousal detectionmedia_commonmedicine.diagnostic_testbusiness.industry020206 networking & telecommunicationsSubject (documents)ElectroencephalographySignal Processing Computer-AssistedAtomic and Molecular Physics and Opticsnormalization020201 artificial intelligence & image processingArtificial intelligencebusinessArousalcomputerSensors
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Privacy preserving via tree augmented naïve Bayesian classifier in multimedia database

2011

International audience; In this paper, we propose a novel technique for privacy preserving in multimedia databases. Our technique is based on a multimedia co-occurrence matrix and a tree augmented naive Bayesian classifier (TAN) to detect possible data associations making confidential multimedia objects at risk.

Novel technique[ INFO.INFO-IR ] Computer Science [cs]/Information Retrieval [cs.IR][INFO.INFO-WB] Computer Science [cs]/WebComputer scienceMultimedia database[ INFO.INFO-WB ] Computer Science [cs]/Web[SCCO.COMP]Cognitive science/Computer science02 engineering and technologycomputer.software_genre[SCCO.COMP] Cognitive science/Computer science020204 information systems0202 electrical engineering electronic engineering information engineering[INFO.INFO-DB] Computer Science [cs]/Databases [cs.DB][ INFO.INFO-MM ] Computer Science [cs]/Multimedia [cs.MM][INFO.INFO-MM] Computer Science [cs]/Multimedia [cs.MM][INFO.INFO-DB]Computer Science [cs]/Databases [cs.DB]Naive bayesian classifier[INFO.INFO-WB]Computer Science [cs]/Web[INFO.INFO-MM]Computer Science [cs]/Multimedia [cs.MM]Privacy preservingTree (data structure)[ INFO.INFO-DB ] Computer Science [cs]/Databases [cs.DB][INFO.INFO-IR]Computer Science [cs]/Information Retrieval [cs.IR][ SCCO.COMP ] Cognitive science/Computer science020201 artificial intelligence & image processing[INFO.INFO-IR] Computer Science [cs]/Information Retrieval [cs.IR]Data miningcomputerProceedings of the International Conference on Management of Emergent Digital EcoSystems
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Constraints on the extremely-high energy cosmic neutrino flux with the IceCube 2008-2009 data

2011

We report on a search for extremely-high energy neutrinos with energies greater than $10^6$ GeV using the data taken with the IceCube detector at the South Pole. The data was collected between April 2008 and May 2009 with the half completed IceCube array. The absence of signal candidate events in the sample of 333.5 days of livetime significantly improves model independent limit from previous searches and allows to place a limit on the diffuse flux of cosmic neutrinos with an $E^{-2}$ spectrum in the energy range $2.0 \times 10^{6}$ $-$ $6.3 \times 10^{9}$ GeV to a level of $E^2 \phi \leq 3.6 \times 10^{-8}$ ${\rm GeV cm^{-2} sec^{-1}sr^{-1}}$.

Nuclear and High Energy PhysicsCosmology and Nongalactic Astrophysics (astro-ph.CO)Astrophysics::High Energy Astrophysical PhenomenaFluxFOS: Physical sciencesCosmic rayRaysAstrophysicsParticle detectorHigh Energy Physics - ExperimentHigh Energy Physics - Experiment (hep-ex)Spectrumddc:530Instrumentation and Methods for Astrophysics (astro-ph.IM)PhysicsSPECTRUMCOSMIC cancer databaseRAYS004Massless particleNeutrino detectorPhysics and AstronomyNeutrinoAstrophysics - Instrumentation and Methods for Astrophysicsinfo:eu-repo/classification/ddc/004Astrophysics - Cosmology and Nongalactic AstrophysicsLepton
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Development of a Reference Database for Beta-Delayed Neutron Emission

2021

Beta-delayed neutron emission is important for nuclear structure and astrophysics as well as for reactor applications. Significant advances in nuclear experimental techniques in the past two decades have led to a wealth of new measurements that remain to be incorporated in the databases. We report on a coordinated effort to compile and evaluate all the available beta-delayed neutron emission data. The different measurement techniques have been assessed and the data have been compared with semi-microscopic and microscopic-macroscopic models. The new microscopic database has been tested against aggregate total delayed neutron yields, time-dependent group parameters in 6-and 8-group re-present…

Nuclear and High Energy PhysicsFissile material010308 nuclear & particles physicsNeutron emissionAstrophysics::High Energy Astrophysical PhenomenaAggregate (data warehouse)Nuclear TheoryNuclear dataFOS: Physical sciences[PHYS.NEXP]Physics [physics]/Nuclear Experiment [nucl-ex]01 natural sciencesNuclear physicsBeta (plasma physics)0103 physical sciencesReference databaseEnvironmental scienceNuclear Experiment (nucl-ex)010306 general physicsNuclear ExperimentDelayed neutronNuclear Experiment
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Energy spectrum of cosmic protons and helium nuclei by a hybrid measurement at 4300 m a.s.l.

2014

The energy spectrum of cosmic Hydrogen and Helium nuclei has been measured, below the so-called "knee", by using a hybrid experiment with a wide field-of-view Cherenkov telescope and the Resistive Plate Chamber (RPC) array of the ARGO-YBJ experiment at 4300 m above sea level. The Hydrogen and Helium nuclei have been well separated from other cosmic ray components by using a multi-parameter technique. A highly uniform energy resolution of about 25% is achieved throughout the whole energy range (100 TeV - 700 TeV). The observed energy spectrum is compatible with a single power law with index gamma=-2.63+/-0.06.

Nuclear and High Energy PhysicsHydrogenAstrophysics::High Energy Astrophysical PhenomenaARGO-YBJFOS: Physical scienceschemistry.chemical_elementCosmic rayHigh Energy Physics - Experimentlaw.inventionNuclear physicsTelescopeHigh Energy Physics - Experiment (hep-ex)lawInstrumentationCherenkov radiationHeliumHigh Energy Astrophysical Phenomena (astro-ph.HE)PhysicsRange (particle radiation)COSMIC cancer databaseSettore FIS/01 - Fisica SperimentaleAstrophysics::Instrumentation and Methods for AstrophysicsHybrid measurementAstronomy and AstrophysicsAlpha particlechemistryCherenkov telescopeEnergy SpectrumAstrophysics - High Energy Astrophysical PhenomenaComposition
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Detecting the long-distance structure of the X(3872)

2014

We study the X(3872)-->D^0 \bar D^0 \pi^0 decay within a D \bar D^* molecular picture for the X(3872) state. This decay mode is more sensitive to the long-distance structure of the X(3872) resonance than its J/\psi\pi\pi and J/\psi3\pi decays, which are mainly controlled by the details of the X(3872) wave function at short distances. We show that the D^0 \bar D^0 final state interaction can be important, and that a precise measurement of this partial decay width can provide valuable information on the interaction strength between the D^{(*)} \bar D^{(*)} charm mesons.

Nuclear and High Energy PhysicsParticle physicsMeson[PHYS.NUCL]Physics [physics]/Nuclear Theory [nucl-th][SDU.ASTR.CO]Sciences of the Universe [physics]/Astrophysics [astro-ph]/Cosmology and Extra-Galactic Astrophysics [astro-ph.CO]Structure (category theory)FOS: Physical sciencesInteraction strength01 natural sciencesHigh Energy Physics - Experiment[PHYS.ASTR.CO]Physics [physics]/Astrophysics [astro-ph]/Cosmology and Extra-Galactic Astrophysics [astro-ph.CO]High Energy Physics - Experiment (hep-ex)High Energy Physics - Phenomenology (hep-ph)[PHYS.QPHY]Physics [physics]/Quantum Physics [quant-ph]0103 physical sciences[PHYS.PHYS.PHYS-INS-DET]Physics [physics]/Physics [physics]/Instrumentation and Detectors [physics.ins-det]010306 general physicsWave functionComputer Science::DatabasesPhysics010308 nuclear & particles physicsHigh Energy Physics::PhenomenologyResonanceFísicaHigh Energy Physics - PhenomenologyHigh Energy Physics::ExperimentBar (unit)X(3872)
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