Search results for "Database"

showing 10 items of 2136 documents

A Comparative Study of Nonlinear Machine Learning for the "In Silico" Depiction of Tyrosinase Inhibitory Activity from Molecular Structure.

2011

In the preset report, for the first time, support vector machine (SVM), artificial neural network (ANN), Baye- sian networks (BNs), k-nearest neighbor (k-NN) are applied and compared on two "in-house" datasets to describe the tyrosinase inhibitory activity from the molecular structure. The data set Data I is used for the identification of tyrosi- nase inhibitors (TIs) including 701 active and 728 inactive compounds. Data II consists of active chemicals for potency estimation of TIs. The 2D TOMOCOMD-CARDD atom-based quadratic indices are used as molecular descriptors. The de- rived models show rather encouraging results with the areas under the Receiver Operating Characteristic (AURC) curve …

Virtual screeningArtificial neural networkComputer sciencebusiness.industryOrganic ChemistryMachine learningcomputer.software_genreComputer Science ApplicationsSupport vector machineData setStructural BiologyMolecular descriptorTest setDrug DiscoveryMultiple comparisons problemMolecular MedicineArtificial intelligencebusinesscomputerChemical databaseMolecular informatics
researchProduct

Topological virtual screening: a way to find new anticonvulsant drugs from chemical diversity.

2003

A topological virtual screening (tvs) test is presented, which is capable of identifying new drug leaders with anticonvulsant activity. Molecular structures of both anticonvulsant-active and non active compounds, extracted from the Merck Index database, were represented using topological indexes. By means of the application of a linear discriminant analysis to both sets of structures, a topological anticonvulsant model (tam) was obtained, which defines a connectivity function. On the basis of this model, 41 new structures with anticonvulsant activity have been identified by a topological virtual screening.

Virtual screeningBasis (linear algebra)Databases FactualMolecular StructureChemistryOrganic ChemistryClinical BiochemistryPharmaceutical ScienceDiscriminant AnalysisQuantitative Structure-Activity RelationshipTopologyLinear discriminant analysisBiochemistryDatabase indexChemical diversityDrug DesignDrug DiscoveryMolecular MedicineAnticonvulsantsComputer SimulationMolecular BiologyAnticonvulsant drugsTopology (chemistry)Bioorganicmedicinal chemistry letters
researchProduct

Approach to mathematics in textbooks at tertiary level – exploring authors’ views about their texts

2012

The aim of this article is to present and discuss some results from an inquiry into mathematics textbooks authors’ visions about their texts and approaches they choose when new concepts are introduced. Authors’ responses are discussed in relation to results about students’ difficulties with approaching calculus reported by previous research. A questionnaire has been designed and sent to seven authors of the most used calculus textbooks in Norway and four authors have responded. The responses show that the authors mainly view teaching in terms of transmission so they focus mainly on getting the mathematical content correct and ‘clear’. The dominant view is that the textbook is intended to he…

VisionMathematics (miscellaneous)Relation (database)Postsecondary educationApplied MathematicsComputingMilieux_COMPUTERSANDEDUCATIONMathematical contentMathematics educationTertiary levelMathematics instructionEducationMathematicsFocus (linguistics)International Journal of Mathematical Education in Science and Technology
researchProduct

Effects of different lower-limb sensory stimulation strategies on postural regulation-a Systematic review and metaanalysis

2017

Systematic reviews of balance control have tended to only focus on the effects of single lower-limb stimulation strategies, and a current limitation is the lack of comparison between different relevant stimulation strategies. The aim of this systematic review and meta-analysis was to examine evidence of effects of different lower-limb sensory stimulation strategies on postural regulation and stability. Moderate- to high-pooled effect sizes (Unbiased (Hedges' g) standardized mean differences (SMD) = 0.31-0.66) were observed with the addition of noise in a Stochastic Resonance Stimulation Strategy (SRSS), in three populations (i.e., healthy young adults, older adults, and individuals with low…

VisionSocial Scienceslcsh:MedicineStimulationDatabase and Informatics MethodsElderlyMathematical and Statistical Techniques0302 clinical medicineMedicine and Health SciencesPsychologyDatabase SearchingYoung adultlcsh:SciencePostural BalanceMultidisciplinarySensory stimulation therapyPhysicsTextilesCompressionClassical MechanicsSystematic reviewMeta-analysisPhysical Sciences/dk/atira/pure/sustainabledevelopmentgoals/good_health_and_well_beingSensory Perceptionmedicine.symptomStatistics (Mathematics)Research Articlemedicine.medical_specialtyCognitive NeuroscienceSurgical and Invasive Medical ProceduresResearch and Analysis MethodsLower limbClothingMotor Reactions03 medical and health sciencesPhysical medicine and rehabilitationSDG 3 - Good Health and Well-beingPhysical StimulationmedicineHumansStatistical MethodsBalance (ability)Balance and FallsFunctional Electrical Stimulationbusiness.industrylcsh:RBiology and Life Sciences030229 sport sciencesPostural ControlAge GroupsGeriatricsPeople and PlacesCognitive SciencePopulation Groupingslcsh:QbusinessMathematics030217 neurology & neurosurgeryNeuroscienceMeta-AnalysisBalance problemsPLoS ONE
researchProduct

A Probabilistic Classification Procedure Based on Response Time Analysis Towards a Quick Pre-Diagnosis of Student's Attention Deficit

2019

[EN] A classification methodology based on an experimental study is proposed towards a fast pre-diagnosis of attention deficit. Our sample consisted of school-aged children between 8 and 12 years from Valencia, Spain. The study was based on the response time (RT) to visual stimuli in computerized tasks. The process of answering consecutive questions usually follows an ex-Gaussian distribution of the RTs. Specifically, we seek to propose a simple automatic classification scheme of children based on the most recent evidence of the relationship between RTs and ADHD. Specifically, the prevalence percentage and reported evidence for RTs in relation to ADHD or to attention deficit symptoms were t…

Visual perceptionRelation (database)Process (engineering)General Mathematicsattention deficit hyperactivity disorder (ADHD) reaction time ex-Gaussian analysis.Sample (statistics)behavioral disciplines and activities050105 experimental psychology03 medical and health sciences0302 clinical medicineComputer Science (miscellaneous)medicineSelection (linguistics)0501 psychology and cognitive sciencesOverdiagnosisEngineering (miscellaneous)Reaction timeProbabilistic classificationlcsh:MathematicsEx-Gaussian analysis05 social sciencesCognitive disorderAttention deficit hyperactivity disorder (ADHD)medicine.diseaselcsh:QA1-939PsychologyMATEMATICA APLICADA030217 neurology & neurosurgeryCognitive psychology
researchProduct

GreekLex 2: A comprehensive lexical database with part-of-speech, syllabic, phonological, and stress information

2017

Databases containing lexical properties on any given orthography are crucial for psycholinguistic research. In the last ten years, a number of lexical databases have been developed for Greek. However, these lack important part-of-speech information. Furthermore, the need for alternative procedures for calculating syllabic measurements and stress information, as well as combination of several metrics to investigate linguistic properties of the Greek language are highlighted. To address these issues, we present a new extensive lexical database of Modern Greek (GreekLex 2) with part-of-speech information for each word and accurate syllabification and orthographic information predictive of stre…

VocabularyDatabases FactualComputer scienceSocial Scienceslcsh:Medicinecomputer.software_genreLexical databaseVocabulary0302 clinical medicinePsychologylcsh:ScienceLanguagemedia_commonPsycholinguisticsMultidisciplinaryGreeceSyllabification05 social sciencesModern GreekSyllablesPhoneticsGreek languagePhysical SciencesSyllabic verseSyllableNatural language processingResearch ArticleStatistical Distributionsmedia_common.quotation_subjectDNA transcriptionGrammatical categoryPhonology050105 experimental psychology03 medical and health sciencesPhoneticsGeneticsHumansSpeech0501 psychology and cognitive sciencesVowelsbusiness.industrylcsh:RPhonetic transcriptionCognitive PsychologyBiology and Life SciencesLinguisticsProbability TheoryPart of speechCognitive Sciencelcsh:QGene expressionArtificial intelligencebusinesscomputerMathematics030217 neurology & neurosurgeryOrthographyNeurosciencePLOS ONE
researchProduct

Towards an Ontology for Information Systems Development—A Contextual Approach

2007

This chapter presents an ISD ontology, which aims to provide an integrated conceptualization of ISD through anchoring it upon a contextual approach. The ISD ontology is composed of concepts, relationships, and constraints referring to purposes, actors, actions, and objects of ISD. It is presented as a vocabulary with explicit definitions and in meta models in a UML-based ontology representation language. We believe that although not complete the ISD ontology can promote the achievement of a shared understanding of contextual aspects in ISD. It can be used to analyze and compare existing frameworks and meta models and as a groundwork for engineering new ISD methods, and parts thereof. IGI PU…

VocabularyKnowledge managementConceptualizationbusiness.industryComputer scienceSuitemedia_common.quotation_subjectOntology (information science)Database designWorld Wide WebUnified Modeling LanguagePublishingInformation systembusinesscomputermedia_commoncomputer.programming_language
researchProduct

Optimal configuration for size-based burst assembly algorithms at the edge node for video traffic transmissions over OBS networks

2008

Optical burst switching (OBS) has been proposed to be a technology for implementing the next generation optical Internet. In this architecture, burst assembly algorithms have an important influence in the pattern traffic that characteristic this sort of optical networks. On the other hand, traffic coming from new applications (such as video on demand, Voice over IP, online gaming or Grid computing) that have real time and bandwidth constraints, has been experimented a rapid increment. Consequently, we consider important to evaluate the performance of traffic from real time applications over OBS networks. In this paper, we evaluate the effects of implementing a size-based burst assembly sche…

Voice over IPRelation (database)business.industryComputer scienceReal-time computing020206 networking & telecommunications02 engineering and technologyData losscomputer.software_genreOptical burst switchingGrid computing0202 electrical engineering electronic engineering information engineeringBandwidth (computing)sort020201 artificial intelligence & image processingThe InternetbusinesscomputerAlgorithmComputer network
researchProduct

On-line database of voltammetric data of immobilized particles for identifying pigments and minerals in archaeometry, conservation and restoration (E…

2016

[EN] A web-based database of voltammograms is presented for characterizing artists' pigments and corrosion products of ceramic, stone and metal objects by means of the voltammetry of immobilized particles methodology. Description of the website and the database is provided. Voltammograms are, in most cases, accompanied by scanning electron microphotographs, X-ray spectra, infrared spectra acquired in attenuated total reflectance Fourier transform infrared spectroscopy mode (ATR-FTIR) and diffuse reflectance spectra in the UV-Vis-region. For illustrating the usefulness of the database two case studies involving identification of pigments and a case study describing deterioration of an archae…

Voltammetry of immobilized particlesDatabasePigmentsCorrosion productsAnalytical chemistryMineralogyInfrared spectroscopy02 engineering and technologycomputer.software_genre01 natural sciencesBiochemistryAnalytical ChemistryArchaeological scienceConservationDiffuse reflectance spectraEnvironmental ChemistryCeramicFourier transform infrared spectroscopySpectroscopyMetallic ObjectDatabaseChemistry010401 analytical chemistry021001 nanoscience & nanotechnology0104 chemical sciencesvisual_artAttenuated total reflectionPINTURAvisual_art.visual_art_medium0210 nano-technologycomputer
researchProduct

Extended Poster Abstract: Open Source Solution for Massive Map Sheet Georeferencing Tasks for Digital Archiving

2010

Scanned maps need to be georeferenced, to be useful in a GIS environment for data extraction (vectorization), web publishing or spatially-aware archiving. Widely used software solutions with georeferencing functionality are designed to suit a universal scenario for georeferencing many different kinds of data sources. Such general nature also makes them very time-consuming for georeferencing a large number of map sheets to a known grid. This work presents an alternative scenario for georeferencing large numbers of map sheets in a time-efficient manner and implements the approach as the MapSheetAutoGeoRef plug-in for the freely available open source Quantum GIS [1].

Web publishingDatabaseComputer sciencebusiness.industryInformationSystems_DATABASEMANAGEMENTcomputer.software_genreGridOpen sourceSoftwareData extractionGeoreferenceImage tracingbusinesscomputer
researchProduct