Search results for "Dative"

showing 10 items of 2381 documents

Relationship between preoperative anxiety and postoperative satisfaction in dental implant surgery with intravenous conscious sedation

2008

Purpose: To study if patient preoperative anxiety is related to age and gender and to compare preoperative anxiety with postoperative patient and surgeon satisfaction in dental implant surgery under intravenous conscious sedation. Materials and Methods: Dental implants were placed in 102 patients under local anesthesia and intravenous conscious sedation. The procedures were performed with or without dental extractions, and with or without bone regeneration. Anxiety was evaluated using Corah?s Dental Anxiety Scale and levels of surgeon and patient satisfaction were evaluated on an adapted scale. Results: Low preoperative anxiety was observed in 27.8% of patients, moderate in 50%, and high in…

AdultMalemedicine.medical_specialtyPatient anxietySedationConscious SedationAnxietyJob SatisfactionDental implant surgeryPatient satisfactionSurveys and QuestionnairesmedicineHumansHypnotics and SedativesLocal anesthesiaBone regenerationGeneral DentistryDental Implantsbusiness.industry:CIENCIAS MÉDICAS [UNESCO]SurgeryOtorhinolaryngologyPatient SatisfactionAnesthesiaInjections IntravenousUNESCO::CIENCIAS MÉDICASAnxietyFemaleSurgeryJob satisfactionmedicine.symptombusinessAnesthesia LocalMedicina Oral Patología Oral y Cirugia Bucal
researchProduct

Lipid metabolism during exercise I: Physiological and biochemical characterization of normal healthy male subjects in relation to their physical fitn…

1978

On the basis of maximal oxygen uptake (\(\dot V\)O2 max) 18 normal, healthy men were divided into two groups of equal size: moderately trained subjects (MTR) each having \(\dot V\)O2 max below 65.0 ml·min−1·kg−1 body weight (54.0±8.3) and well trained subjects (WTR), whose \(\dot V\)O2 max exceeded 65.0 ml·min−1·kg−1 body weight (69.2±4.1). The WTR group had slightly (non significant, n.s.) higher percentage of slow twitch, oxidative (SO) fibers in M. vastus lateralis and higher (n.s.) activities of cytochrome c oxidase (CytOx), succinate dehydrogenase (SDH), 3-hydroxyacyl-CoA-dehydrogenase (HADH), and citrate synthase (CS), while lactate dehydrogenase (LDH) activity was lower (n.s.). In th…

AdultMalemedicine.medical_specialtyPhysiologyPhysical fitnessCitrate (si)-SynthaseOxidative phosphorylationBiologyModels BiologicalElectron Transport Complex IVchemistry.chemical_compoundOxygen ConsumptionPhysiology (medical)Internal medicineLactate dehydrogenasemedicineHumansCytochrome c oxidaseCitrate synthaseOrthopedics and Sports MedicineL-Lactate Dehydrogenasebusiness.industryMusclesSuccinate dehydrogenasePublic Health Environmental and Occupational Health3-Hydroxyacyl CoA DehydrogenasesOxo-Acid-LyasesVO2 maxGeneral MedicineSuccinate DehydrogenaseEndocrinologyBiochemistrychemistryPhysical Fitnessbiology.proteinLean body massOxidoreductasesbusinessEuropean Journal of Applied Physiology and Occupational Physiology
researchProduct

Behaviour of protein carbonyl groups in juvenile myocardial infarction.

2012

Acute myocardial infarction (AMI) is accompanied by oxidative stress, and protein oxidation is among the con- sequences of oxidative stress. We examined the plasma concentration of protein carbonyl groups (PC), a marker of protein oxidation, in a group of young subjects with AMI (45 men and 5 women; mean age 40.4 ± 4.8 yrs). We found a significant increase of PC (p < 0.001) in comparison with normal controls. No difference was observed between patients with AMI char- acterized by elevated ST segment and those without elevation of ST segment. There was no correlation between the ejection fraction and PC in the whole group nor in the subgroups of STEMI and non-STEMI patients. Subdividing the …

AdultMalemedicine.medical_specialtyPhysiologyProtein oxidationmedicine.disease_causeProtein CarbonylationRisk FactorsPhysiology (medical)Internal medicinemyocardial infarction; protein oxidationmedicineST segmentJuvenileHumansprotein oxidationcardiovascular diseasesMyocardial infarctionEjection fractionbusiness.industryMean ageHematologymedicine.diseaseSurgeryOxidative Stressmyocardial infarctionAcute DiseaseCardiologyFemaleCardiology and Cardiovascular MedicinebusinessProtein carbonylOxidative stress
researchProduct

Interrelationships between lipid peroxidation and total antioxidant status in sedentary controls and unprofessional athletes.

2010

We examined the thiobarbituric acid-reactive substances (TBARS) as an index of lipid peroxidation, and the total antioxidant status (TAS) in 81 unprofessional athletes subdivided into three subgroups. The first group included 28 subjects who practised endurance sports, the second included 30 subjects who practised mixed sports, the third included 23 subjects who practised power sports. We enrolled also a group of 61 sedentary controls (SC). TBARS were increased and TAS was decreased in the whole group of athletes in comparison with SC; an almost similar behaviour was present also subdividing athletes according to the practised sport. A significant negative correlation between these two para…

AdultMalemedicine.medical_specialtyPhysiologySignificant negative correlationThiobarbituric Acid Reactive SubstancesAntioxidantsLipid peroxidationchemistry.chemical_compoundPhysiology (medical)TBARSMedicineHumansOXIDATIVE STRESS EXERCISE ATHLETEbiologybusiness.industryAthletesHematologySedentary behaviorMiddle Agedbiology.organism_classificationWeight liftingAntioxidant capacitychemistryAthletesPhysical therapyFemaleLipid PeroxidationSedentary BehaviorCardiology and Cardiovascular Medicinebusinesshuman activitiesSportsClinical hemorheology and microcirculation
researchProduct

Oxidative stress and maternal obesity: Feto-placental unit interaction

2013

Abstract Objective To determine oxidative stress markers in maternal obesity during pregnancy and to evaluate feto-placental unit interaction, especially predictors of fetal metabolic alterations. Patients and methods 40 obese pregnant women (prepregnancy BMI > 30 kg/m²) were compared to 50 control pregnant women. Maternal, cord blood and placenta samples were collected at delivery. Biochemical parameters (total cholesterol and triglycerides) and oxidative stress markers (malondialdehyde, carbonyl proteins, superoxide anion expressed as reduced Nitroblue Tetrazolium, nitric oxide expressed as nitrite, reduced glutathione, catalase, superoxide dismutase) were assayed by biochemical methods. …

AdultMalemedicine.medical_specialtyPlacentaNitric Oxidemedicine.disease_causeNitric oxideSuperoxide dismutasechemistry.chemical_compoundPregnancySuperoxidesMalondialdehydeInternal medicinePlacentamedicineHumansObesityMaternal-Fetal ExchangeTriglyceridesFetusPregnancybiologySuperoxide DismutaseSuperoxidebusiness.industryInfant NewbornProteinsObstetrics and GynecologyBlood ProteinsCatalaseFetal Bloodmedicine.diseaseMalondialdehydeGlutathionePregnancy ComplicationsOxidative StressCholesterolEndocrinologymedicine.anatomical_structureReproductive Medicinechemistrybiology.proteinFemalebusinessOxidation-ReductionBiomarkersOxidative stressDevelopmental BiologyPlacenta
researchProduct

ADMA, subclinical changes and atrial fibrillation in the general population.

2015

Abstract Background Pathways of oxidative stress, nitric oxide bioavailability and l-arginine derivatives are hypothesized to be related to atrial fibrillation (AF). Circulating methylated l-arginine metabolites can be assessed in the general population and may show an association with AF. Methods We determined l-arginine and its metabolites asymmetric dimethylarginine (ADMA), l-N ω -monomethylarginine (NMMA) and symmetric dimethylarginine (SDMA) in the population-based Gutenberg Health Study (n=5000), mean age 55±11years, 51% men, in association with clinical variables of AF such as electrocardiographic and echocardiographic measures and manifest AF. Results Individuals with AF (N=161), 71…

AdultMalemedicine.medical_specialtyPopulation030204 cardiovascular system & hematologyArginine03 medical and health scienceschemistry.chemical_compoundQRS complexElectrocardiography0302 clinical medicineTandem Mass SpectrometryInternal medicineGermanyAtrial FibrillationmedicineHumanseducationAgedCreatinineeducation.field_of_studyomega-N-Methylargininebusiness.industryAtrial fibrillationOdds ratioMiddle Agedmedicine.diseaseConfidence interval3. Good healthOxidative StressEndocrinologychemistryEchocardiographyPopulation SurveillanceCardiologyOmega-N-MethylarginineFemaleMorbidityCardiology and Cardiovascular MedicineAsymmetric dimethylargininebusiness030217 neurology & neurosurgeryBiomarkersChromatography LiquidInternational journal of cardiology
researchProduct

Hyperuricemia in acute heart failure. More than a simple spectator?

2007

Hyperuricemia is a prevalent condition in chronic heart failure (CHF), describing increased oxidative stress and inflammation. Although there is evidence that serum uric acid (UA) predicts mortality in CHF, its role as a prognostic biomarker in acute heart failure (AHF) has not yet been well assessed. The aim of this study was to determine if UA levels predict all-cause mortality. Additionally, as a secondary endpoint we sought the clinical predictors of UA serum level in this population.We analyzed 560 consecutive patients with AHF admitted in a single university center. UA (mg/dl) was measured during early hospitalization. Patient survival status was followed up after discharge (median fo…

AdultMalemedicine.medical_specialtyPopulationHyperuricemiaGastroenterologychemistry.chemical_compoundPredictive Value of TestsInternal medicineCause of DeathInternal MedicinemedicineHumansHyperuricemiaIntensive care medicineeducationCause of deathAgedProportional Hazards ModelsAged 80 and overHeart Failureeducation.field_of_studybusiness.industryProportional hazards modelMortality ratemedicine.diseasePrognosisUric AcidOxidative StresschemistryPredictive value of testsHeart failureAcute DiseaseMultivariate AnalysisUric acidFemalebusinessFollow-Up StudiesEuropean journal of internal medicine
researchProduct

Nonmedical use of prescription drugs in the European Union

2016

Background Nonmedical prescription drug use (NMPDU) refers to the self-treatment of a medical condition using medication without a prescriber’s authorization as well as use to achieve euphoric states. This article reports data from a cross-national investigation of NMPDU in five European Countries, with the aim to understand the prevalence and characteristics of those engaging in NMPDU across the EU. Methods A parallel series of self-administered, cross-sectional, general population surveys were conducted in 2014. Data were collected using multi-stage quota sampling and then weighted using General Exponential Model. A total of 22,070 non-institutionalized participants, aged 12 to 49 years, …

AdultMalemedicine.medical_specialtyPrescription drugPrescription DrugsCross-sectional studySubstance-Related Disordersmedicine.medical_treatmentDenmarkPopulationPharmacyThinking03 medical and health sciencesYoung Adult0302 clinical medicineRisk FactorsGermanymedicinePrevalencemedia_common.cataloged_instanceHypnotics and SedativesHumans030212 general & internal medicineEuropean UnionEuropean unionMedical prescriptionPsychiatryeducationPrescription Drug MisuseReproductive healthmedia_commonSwedeneducation.field_of_studybusiness.industryUnited KingdomStimulantAnalgesics OpioidEuropePsychiatry and Mental healthCross-Sectional StudiesSpainCentral Nervous System StimulantsFemalebusiness030217 neurology & neurosurgeryResearch ArticleBMC Psychiatry
researchProduct

Analysis of thiamine transporter genes in sporadic beriberi

2014

Abstract Objective Thiamine or vitamin B 1 deficiency diminishes thiamine-dependent enzymatic activity, alters mitochondrial function, impairs oxidative metabolism, and causes selective neuronal death. We analyzed for the first time, the role of all known mutations within three specific thiamine carrier genes, SLC19 A2, SLC19 A3 , and SLC25 A19 , in a patient with atrophic beriberi, a multiorgan nutritional disease caused by thiamine deficiency. Methods A 44-year-old male alcoholic patient from Morocco developed massive bilateral leg edema, a subacute sensorimotor neuropathy, and incontinence. Despite normal vitamin B 1 serum levels, his clinical picture was rapidly reverted by high-dose in…

AdultMalemedicine.medical_specialtySLC19 A- SLC25 A19SLC19 AEndocrinology Diabetes and MetabolismGene mutationBeriberimedicine.disease_causeMitochondrial Membrane Transport Proteinslaw.inventionBeriberilawInternal medicineGenotypemedicineThiamine transporterObjective: Thiamine or vitamin B1 deficiency diminishes thiamine-dependent enzymatic activity alters mitochondrial function impairs oxidative metabolism and causes selective neuronal death. We analyzed for the first time the role of all known mutations within three specific thiamine carrier genes SLC19 A2 SLC19 A3 and SLC25 A19 in a patient with atrophic beriberi a multiorgan nutritional disease caused by thiamine deficiency. Methods: A 44-year-old male alcoholic patient from Morocco developed massive bilateral leg edema a subacute sensorimotor neuropathy and incontinence. Despite normal vitamin B1 serum levels his clinical picture was rapidly reverted by high-dose intramuscular thiamine treatment suggesting a possible genetic resistance. We used polymerase chain reaction followed by amplicon sequencing to study all the known thiamine-related gene mutations identified within the Human Gene Mutation Database. Results: Thirty-seven mutations were tested: 29 in SLC19 A2 6 in SLC19 A3 and 2 in SLC25 A19. Mutational analyses showed a wild-type genotype for all sequences investigated. Conclusion: This is the first genetic study in beriberi disease. We did not detect any known mutation in any of the three genes in a sporadic dry beriberi patient. We cannot exclude a role for other known or unknown mutations in the same genes or in other thiamine-associated genes in the occurrence of this nutritional neuropathy.HumansThiamineGenePolymerase chain reactionGeneticsMutationNutrition and DieteticsbiologyMembrane Transport ProteinsThiamine Deficiencymedicine.diseaseAlcoholismEndocrinologyMutationbiology.proteinThiamineMutations
researchProduct

Assessment of salivary and serum antioxidant status in patients with recurrent aphthous stomatitis

2009

Objective: The aim of this study was to determine the possible association of oxidant/antioxidant status and recurrent aphthous stomatitis (RAS). Study design: The study consis ted of thirty-one patients with RAS and thirty-two healthy controls from whom saliva and blood samples were collected. Superoxide dismutase (SOD), glutathione peroxidase (GSHPx) and catalase (CAT) were measured in erythrocytes and total antioxidant status (TAS) was measured in plasma and saliva. Results: Erythrocyte SOD activity was significantly lower in RAS patients in comparison to healthy controls (P=0.012). No significant differences were found in erythrocyte GSHPx, CAT activities, and salivary and plasma TAS be…

AdultMalemedicine.medical_specialtySalivaAntioxidantmedicine.medical_treatmentRecurrent aphthous stomatitisSuperoxide dismutaseRecurrenceInternal medicinemedicineHumansIn patientSalivaGeneral Dentistrychemistry.chemical_classificationGlutathione PeroxidasebiologySuperoxide Dismutasebusiness.industryGlutathione peroxidase:CIENCIAS MÉDICAS [UNESCO]CatalaseControl subjectsOxidative StressEndocrinologyOtorhinolaryngologychemistryCatalaseUNESCO::CIENCIAS MÉDICASbiology.proteinFemaleStomatitis AphthousSurgerybusiness
researchProduct