Search results for "Decision model"
showing 3 items of 13 documents
SMAA in Robustness Analysis
2016
Stochastic multicriteria acceptability analysis (SMAA) is a simulation based method for discrete multicriteria decision aiding problems where information is uncertain, imprecise, or partially missing. In SMAA, different kind of uncertain information is represented by probability distributions. Because SMAA considers simultaneously the uncertainty in all parameters, it is particularly useful for robustness analysis. Depending on the problem setting, SMAA determines all possible rankings or classifications for the alternatives, and quantifies the possible results in terms of probabilities. This chapter describes SMAA in robustness analysis using a real-life decision problem as an example. Bas…
A new decision model for economic evaluation of novel therapies for HCV
2014
In 2014, the European Medicines Agency (EMA) has given the license to two new direct-acting antiviral: sofosbuvir and simeprevir. The evidence provided by the studies, reported a high rate of SVR even in patients with decompensated cirrhosis. This and other innovative elements are potentially adept at changing the entire natural course of HCV. However, the dramatic prevalence rates of HCV observed in Italy, and the high prices that are expected to be required by the pharmaceutical industry, raises some critical issues about how to regulate access to such drugs. The objective of this article is to present a new decision model for the evaluation of novel therapies for HCV. This model is inten…