Search results for "Decline"
showing 10 items of 261 documents
Differential effects of age on subcomponents of response inhibition.
2013
Inhibitory deficits contribute to cognitive decline in the aging brain. Separating subcomponents of response inhibition may help to resolve contradictions in the existing literature. A total of 49 healthy participants underwent functional magnetic resonance imaging (fMRI) while performing a Go/no-go-, a Simon-, and a Stop-signal task. Regression analyses were conducted to identify correlations of age and activation patterns. Imaging results revealed a differential effect of age on subcomponents of response inhibition. In a simple Go/no-go task (no spatial discrimination), aging was associated with increased activation of the core inhibitory network and parietal areas. In the Simon task, whi…
alpha-Glycerophosphocholine in the mental recovery of cerebral ischemic attacks. An Italian multicenter clinical trial.
1994
The clinical efficacy and the tolerability of alpha-glycerophosphocholine (alpha-GPC), a drug able to provide high levels of choline for the nervous cells of the brain and to protect their cell walls, have been tested in a clinical open multicenter trial on 2044 patients suffering from recent stroke or transient ischemic attacks. alpha-GPC was administered after the attack at the daily dose of 1000 mg im for 28 days and orally at the dose of 400 mg tid during the following 5 months after the first phase. The evaluation of the efficacy on the psychic recovery was done by the Mathew Scale (MS) during the period of im drug administration, and using the Mini Mental State Test (MMST), the Cricht…
Nasal tactile sensitivity in elderly
2010
Conclusion: Although older people varied widely in tactile sensitivity, our results show that tactile thresholds increased with age. Objectives: The aim of this study was to evaluate the effects of aging on nasal tactile sensitivity. Methods: A total of 160 healthy patients aged between 50 and 90 years were included. According to their age, patients were divided into groups (A, B, C, D, E, F, G, and H). From the age of 50, each group included subjects with an age range of 5 years (i.e. group A, 50-55 years; group B, 56-60 years, etc.). Each patient's outcome was assessed through the nasal monofilament test: a set of 20 Semmes-Weinstein monofilaments was used to detect nasal sensitivity for …
Contextualising the Last Survivors: Population Structure of Marine Turtles in the Dominican Republic.
2013
Nesting by three species of marine turtles persists in the Dominican Republic, despite historic threats and long-term population decline. We conducted a genetic survey of marine turtles in the Dominican Republic in order to link them with other rookeries around the Caribbean. We sequenced a 740bp fragment of the control region of the mitochondrial DNA of 92 samples from three marine turtle species [hawksbill (n = 48), green (n = 2) and leatherback (n = 42)], and incorporated published data from other nesting populations and foraging grounds. The leatherback turtle (Dermochelys coriacea) in the Dominican Republic appeared to be isolated from Awala-Yalimapo, Cayenne, Trinidad and St. Croix bu…
Walking Stroop carpet: an innovative dual-task concept for detecting cognitive impairment
2013
A Perrochon,1,2,5 G Kemoun,1,2 E Watelain,3,4 A Berthoz51ISIS, Research Institute on Handicap and Aging, Paris; 2Université de Poitiers, Laboratoire Mobilité, Vieillissement et Exercice (MOVE), EA 6314, 3Université de Valenciennes, LAMIH, UMR CNRS 8201, 4Université Sud Toulon Var, HandiBio, EA 4322, La Garde, 5LPPA, UMR CNRS 7152, Collège de France, Paris, FranceBackground: Several studies have reported the potential value of the dual-task concept during locomotion in clinical evaluation because cognitive decline is strongly associated with gait abnormalities. However, current dual-task tests appear to be insufficient for early diagnosi…
DISTRIBUTION OF BOTRYOSPHAERIACEAE SPECIES ASSOCIATED WITH GRAPEVINE DECLINE IN WESTERN SICILY.
2011
Recently, the pathogenicity of different Botryosphaeraceae species on grapevines has been reported from many European and extra-European areas. During summer 2008, in a Sicilian vineyard located in the Marsala area (TP), we observed a decline induced by Lasiodiplodia theobromae. The occurrence and quite rapid spread of the disease seemed to support the regional variability of the species in question, which is retained a tropical and subtropical pathogen to different trees. In the last two years, the decline syndrome has been observed in the following other grape-growing areas of western and central Sicily: Alcamo and Salemi (TP), Montevago (AG) and Milena (CL). From declining plants showing…
Recovery of cork forests and enhancement of by-products
2022
Cork oak (Quercus suber L.) is a tree species native to the western Mediterranean Basin (EUFORGEN 2019). Cork oak forests are human-shaped ecosystems that have to be managed to be preserved in a long-term perspective. Cork oak stands range from closed forests to open woodlands, provide high ecosystem services, mainly through cork production, support high biodiversity and provide carbon storage and water regulation services. Due to their important ecological role, these ecosystems are listed in the European Habitats Directive (Habitat 9330: Quercus suber forests, EEC, 1992). In the last years, especially in Italy, cork oak stands are undergoing a relevant regression due to the decline of tra…
Spatial Bayesian Modeling Applied to the Surveys of Xylella fastidiosa in Alicante (Spain) and Apulia (Italy)
2020
The plant-pathogenic bacterium Xylella fastidiosa was first reported in Europe in 2013, in the province of Lecce, Italy, where extensive areas were affected by the olive quick decline syndrome, caused by the subsp. pauca. In Alicante, Spain, almond leaf scorch, caused by X. fastidiosa subsp. multiplex, was detected in 2017. The effects of climatic and spatial factors on the geographic distribution of X. fastidiosa in these two infested regions in Europe were studied. The presence/absence data of X. fastidiosa in the official surveys were analyzed using Bayesian hierarchical models through the integrated nested Laplace approximation (INLA) methodology. Climatic covariates were obtained from …
L’IPOTIROIDISMO NELLE PERSONE ANZIANE: IMPORTANZA DI UNA ADEGUATA TERAPIA SOSTITUTIVA ORMONALE
2013
La prevalenza dei disturbi della ghiandola tiroidea aumenta con l’età, soprattutto nelle donne. L’ipofunzione tiroidea conclamata in età avanzata può manifestarsi clinicamente con sintomi e segni simili alle modificazioni che normalmente accompagnano l’invecchiamento o come disturbi di altri organi. Per tale motivo, un alto indice di sospetto è essenziale per rilevare l’ipotiroidismo in anziani con comorbilità multiple, alterazioni nutrizionali e/o polifarmacoterapia. La decisione di iniziare una terapia sostitutiva ormonale nell’ipotiroidismo conclamato non è discutibile. Viceversa, esiste ancora controversia sulla decisione di trattare o non trattare l’ipotiroidismo subclinico; le raccoma…
Niemann-Pick disease type C symptomatology: an expert-based clinical description
2013
Niemann-Pick disease type C (NP-C) is a rare, progressive, irreversible disease leading to disabling neurological manifestations and premature death. The estimated disease incidence is 1:120,000 live births, but this likely represents an underestimate, as the disease may be under-diagnosed due to its highly heterogeneous presentation. NP-C is characterised by visceral, neurological and psychiatric manifestations that are not specific to the disease and that can be found in other conditions. The aim of this review is to provide non-specialists with an expert-based, detailed description of NP-C signs and symptoms, including how they present in patients and how they can be assessed. Early dise…