Search results for "Deep Brain Stimulation"

showing 6 items of 46 documents

Comparison of Shod and Unshod Gait in Patients With Parkinson's Disease With Subthalamic and Nigral Stimulation

2022

Background: The Parkinsonian [i.e., Parkinson's disease (PD)] gait disorder represents a therapeutical challenge with residual symptoms despite the use of deep brain stimulation of the subthalamic nucleus (STN DBS) and medical and rehabilitative strategies. The aim of this study was to assess the effect of different DBS modes as combined stimulation of the STN and substantia nigra (STN+SN DBS) and environmental rehabilitative factors as footwear on gait kinematics.Methods: This single-center, randomized, double-blind, crossover clinical trial assessed shod and unshod gait in patients with PD with medication in different DBS conditions (i.e., STIM OFF, STN DBS, and STN+SN DBS) during differe…

barefootsubthalamic nucleusParkinson's diseaseHuman NeuroscienceNeurosciences. Biological psychiatry. NeuropsychiatryBrief Research Reportshoesgaitbehavioral disciplines and activitiesnervous system diseasesdeep brain stimulationBehavioral NeurosciencePsychiatry and Mental healthNeuropsychology and Physiological Psychologysurgical procedures operativeNeurologynervous systemsubstantia nigratherapeuticsBiological PsychiatryRC321-571Frontiers in Human Neuroscience
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Proceedings of the Eighth Annual Deep Brain Stimulation Think Tank: Advances in Optogenetics, Ethical Issues Affecting DBS Research, Neuromodulatory …

2021

We estimate that 208,000 deep brain stimulation (DBS) devices have been implanted to address neurological and neuropsychiatric disorders worldwide. DBS Think Tank presenters pooled data and determined that DBS expanded in its scope and has been applied to multiple brain disorders in an effort to modulate neural circuitry. The DBS Think Tank was founded in 2012 providing a space where clinicians, engineers, researchers from industry and academia discuss current and emerging DBS technologies and logistical and ethical issues facing the field. The emphasis is on cutting edge research and collaboration aimed to advance the DBS field. The Eighth Annual DBS Think Tank was held virtually on Septem…

medicine.medical_specialtyDeep brain stimulationCoronavirus disease 2019 (COVID-19)medicine.medical_treatmentDBSNeurosciences. Biological psychiatry. NeuropsychiatryBioengineeringOptogeneticsneuroethicsBehavioral NeurosciencemedicinePsychologyMedical physicsPooled dataadaptive DBSnovel hardwareoptogeneticsNeurostimulationBiological PsychiatryDepression (differential diagnoses)Assistive TechnologyneuroimagingEthical issuesDepressionRehabilitationNeurosciencesDBS (deep brain stimulation)Experimental PsychologyBrain DisordersPsychiatry and Mental healthNeuropsychology and Physiological PsychologyMental HealthNeurologyPerspectiveNeurologicalCognitive SciencesNeuroethicsPsychologyNeuroscienceRC321-571
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Letter: Risk Factors for Wire Fracture or Tethering in Deep Brain Stimulation: A 15-Year Experience

2021

medicine.medical_specialtyDeep brain stimulationTetheringbusiness.industrymedicine.medical_treatmentDeep Brain StimulationMEDLINEElectrodes ImplantedPhysical medicine and rehabilitationText miningRisk FactorsFracture (geology)medicineHumansSurgeryNeurology (clinical)businessBone Wires
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Migraine and cluster headache – the common link

2018

Abstract Although clinically distinguishable, migraine and cluster headache share prominent features such as unilateral pain, common pharmacological triggers such glyceryl trinitrate, histamine, calcitonin gene-related peptide (CGRP) and response to triptans and neuromodulation. Recent data also suggest efficacy of anti CGRP monoclonal antibodies in both migraine and cluster headache. While exact mechanisms behind both disorders remain to be fully understood, the trigeminovascular system represents one possible common pathophysiological pathway and network of both disorders. Here, we review past and current literature shedding light on similarities and differences in phenotype, heritability…

medicine.medical_specialtyNeurologyCluster headacheImplantable Neurostimulators/statistics & numerical dataPain medicineCalcitonin Gene-Related PeptideDeep Brain StimulationMigraine DisordersNitroglycerin/adverse effectsHypothalamuslcsh:MedicineTriptansReviewCalcitonin gene-related peptideBioinformatics03 medical and health sciencesNitroglycerin0302 clinical medicinemedicineHumans030212 general & internal medicineTryptamines/pharmacologyMigraineTrigeminovascular systembusiness.industryNeuromodulationCluster Headache/bloodCluster headacheAnti-CGRP (receptor) monoclonal antibodies – mAbsMigraine Disorders/bloodTrigeminovascular systemlcsh:RGeneral MedicineCalcitonin gene-related peptide (CGRP)medicine.diseaseDeep Brain Stimulation/statistics & numerical dataNeuromodulation (medicine)Tryptamines3. Good healthCalcitonin Gene-Related Peptide/antagonists & inhibitorsAnesthesiology and Pain MedicineImplantable NeurostimulatorsMigraineNeurology (clinical)business030217 neurology & neurosurgerymedicine.drugThe Journal of Headache and Pain
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Restoring Neurological Physiology: The Innovative Role of High-Energy MR-Guided Focused Ultrasound (HIMRgFUS). Preliminary Data from a New Method of …

2017

Background Tremor is a disabling condition, common to several neurodegenerative diseases. Lesioning procedures and deep brain stimulation, respectively, of the ventralis intermedius nucleus for intentional tremor, and of the subthalamic nucleus for parkinsonian resting tremor, have been introduced in clinical practice for patients refractory to medical treatment. The combination of high-energy focused ultra-sound (HIFUS) with sophisticated magnetic resonance (MR) instrumentation, together with accurate knowledge of the stereotactic brain coordinates, represents a revolution in neuromodulation. Methods At the Neurosurgical Clinic and the Radiology Department of the University of Palermo,, tw…

medicine.medical_specialtyParkinson's diseaseDeep brain stimulationmedicine.medical_treatmentNeurosurgical ProcedureSeverity of Illness IndexNeurosurgical ProceduresFocused ultrasoundMRI-guided focused ultrasound (MRgFUS)03 medical and health sciences0302 clinical medicineTremormedicineHumans030212 general & internal medicineResting tremorVentral Thalamic Nucleimedicine.diagnostic_testEssential tremorSettore MED/27 - Neurochirurgiabusiness.industryEssential tremor; functional neurosurgery; lesioning surgery; MRI-guided focused ultrasound (MRgFUS); Parkinson’s disease; brain; high-intensity focused ultrasound ablation; humans; magnetic resonance imaging; neurosurgical procedures; severity of illness index; surgery computer-assisted; tremor; ventral thalamic nucleiSettore MED/37 - NeuroradiologiaBrainMagnetic resonance imagingLesioning surgerymedicine.diseaseMagnetic Resonance ImagingNeuromodulation (medicine)nervous system diseasesSurgerySubthalamic nucleusFunctional neurosurgerySurgery Computer-AssistedParkinson’s diseaseEssential tremorHigh-Intensity Focused Ultrasound AblationSettore MED/36 - Diagnostica Per Immagini E Radioterapiabusiness030217 neurology & neurosurgeryHuman
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Reduced Risk of Reoperations With Modern Deep Brain Stimulator Systems: Big Data Analysis From a United States Claims Database

2021

Objective: There have been significant improvements in the design and manufacturing of deep brain stimulation (DBS) systems, but no study has considered the impact of modern systems on complications. We sought to compare the relative occurrence of reoperations after de novo implantation of modern and traditional DBS systems in patients with Parkinson's disease (PD) or essential tremor (ET) in the United States.Design: Retrospective, contemporaneous cohort study.Setting: Multicenter data from the United States Centers for Medicare and Medicaid Services administrative claims database between 2016 and 2018.Participants: This population-based sample consisted of 5,998 patients implanted with a …

medicine.medical_specialtyPediatricsDeep brain stimulationcomplicationsmedicine.medical_treatmentParkinson's diseasePopulationMedicarebehavioral disciplines and activitiesmedicineneurosurgeryeducationProspective cohort studyessential tremorRC346-429Original Researcheducation.field_of_studyEssential tremorbusiness.industrymedicine.diseasedeep brain stimulationbig data & analyticsnervous systemNeurologyNeurology (clinical)NeurosurgeryNeurology. Diseases of the nervous systemComplicationbusinessMedicaidCohort studysurgical riskFrontiers in Neurology
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