Search results for "Defence"

Determination of pollutants with multixenobiotic -resistance inhibiting properties

1995

Abstract Recent evidence indicates that inherent presence of multixenobiotic resistance (MXR) mechanism represents a general biological defence mechanism for protection of organisms against both endogenous and environmental toxins. In aquatic organisms exposed to polluted waters, this P-170 glycoprotein pump also removes ‘new’ man-made toxic chemicals out of cells. Many chemical agents may alter the function of this fragile mechanism. A new class of compounds, referred to as ‘chemosensitizers’, deserve a top rank among environmentally-hazardous chemicals, since they block this basic natural defence mechanism. The authors measured the concentration of such MXR-inhibiting substances by two me…

The Impact of Copper Ions on Oxidative Stress in Garden Cress Lepidium sativum

2017

Abstract Normal oxygen metabolism is an endogenous source of reactive oxygen species (ROS). The source of ROS are also many environmental factors including heavy metals. In certain concentration range, the presence of ROS is necessary to maintain proper cell function. Thus, cells have many mechanisms, which role is focused on maintaining a constant concentration of ROS. Imbalance between the formation of ROS and action of a protective antioxidant system leads to oxidative stress. This may results with a damage to the structure of proteins, lipids and nucleic acids, which in turn can lead to disturbances in the functioning of the cell and even to the death. The aim of the study was to evalua…

Profiles and Sources of PAHs in Sediments from an Open-Pit Mining Area in the Peruvian Andes

2015

The Peruvian Andes are one of the most productive areas for mining and therefore also one of the most exposed to these sources of pollution. This article reports the characterization of Polycyclic Aromatic Hydrocarbons (PAHs) in sediments of Cerro de Pasco area (Peru) located close to a large open-pit mine and, in recent years, several reports have provided evidence of environmental contamination and related health problems. Investigations were carried out into the fifteen PAHs identified by the US-Environment Protection Agency (US-EPA) as requiring priority monitoring, other non US-EPA listed PAHs and perylene were also investigated in order to obtain further information on their origins. …

Brief communication: Vehicle routing problem and UAV application in the post-earthquake scenario

2017

Abstract. In this paper we simulate a Unmanned Aerial Vehicle's (UAV) recognition after a possible case of diffuse damage after a seismic event in the town of Acireale (Sicily, Italy). Given a set of sites (84 relevant buildings) and the range of the UAV, we are able to find the number of vehicles to employ and the shortest survey path. The problem of finding the shortest survey path is an operational research problem called Vehicle Routing Problem (VRP) whose solution is known to be computationally time-consuming. We used the Simulated Annealing (SA) heuristic that is able to provide stable solutions in relatively short computing time. We also examined the distribution of the cost of the s…

The Power of Literature to Decipher the Archetype of Lone-Wolf

2021

The Soviet Union collapse marked the end of the Cold War and the rise of the US as the only superpower, at least until 9/11, a foundational event where four civil aeroplanes were directed against the commercial and military hallmarks of the most powerful nation. Terrorism and the so-called War on Terror characterized the turn of a bloody century whose legacy remains to date. The chapter explores the dilemmas of lone-wolf terrorism from the lens of literature as well as cultural theory. The authors hold the thesis that terrorism activates some long-dormant narrative forged in the colonial period respecting to the “non-Western other.” Having said this, the chapter dissects the plot of some no…

PROTOCOL: Organised crime groups: A systematic review of individual‐level risk factors related to recruitment

2019

Informal Disaster Governance

2020

<p>Scholars and practitioners are increasingly questioning formal disaster governance (FDG) approaches as being too rigid, slow, and command-and-control driven. Too often, local realities and non-formal influences are sidelined or ignored to the extent that disaster governance can be harmed through the efforts to impose formal and/or political structures. A contrasting narrative emphasises so-called bottom-up, local, and/or participatory approaches which this article proposes to encapsulate as Informal Disaster Governance (IDG). This article theorises IDG and situates it within the long-standing albeit limited literature on the topic, paying particular attention to the literature’s fa…

Comparing in vivo data and in silico predictions for acute effects assessment of biocidal active substances and metabolites for aquatic organisms.

2020

Abstract The purpose of this study was to determine the acute toxicity in aquatic organisms of one biocidal active substance and six metabolites derived from biocidal active substances and to assess the suitability of available QSAR models to predict the obtained values. We have reported the acute toxicity in sewage treatment plant (STP) microorganisms, in the freshwater microalgae Pseudokirchneriella subcapitata and in Daphnia magna following OECD test methods. We have also identified in silico models for acute toxicity of these trophic levels currently available in widely recognized platforms such as VEGA and the OECD QSAR ToolBox. A total of six, four and two models have been selected fo…

Prediction of acute toxicity of phenol derivatives using multiple linear regression approach for Tetrahymena pyriformis contaminant identification in…

2016

In this article, the modeling of inhibitory grown activity against Tetrahymena pyriformis is described. The 0-2D Dragon descriptors based on structural aspects to gain some knowledge of factors influencing aquatic toxicity are mainly used. Besides, it is done by some enlarged data of phenol derivatives described for the first time and composed of 358 chemicals. It overcomes the previous datasets with about one hundred compounds. Moreover, the results of the model evaluation by the parameters in the training, prediction and validation give adequate results comparable with those of the previous works. The more influential descriptors included in the model are: X3A, MWC02, MWC10 and piPC03 wit…

¿Cómo se define el liderazgo en la defensa europea? Un análisis fsQCA

2017

The paper addresses the issue of national leadership in the politics of European defence, in order to determine the relative value of different factors in the exercise of leadership, and the reasons why some countries are more willing than others to contribute to the development of the EU’s Common Security and Defence Policy. The article starts by discussing the main contributions of the (neo)realist and constructivist approaches to European leadership on defence. It then highlights the process of development of EU defence policy and its setbacks. Leadership factors that characterize this development process are identified and employed to construct a fsQCA analysis, which assesses the leade…