Search results for "Delta"

showing 10 items of 471 documents

Very High Fascioliasis Intensities in Schoolchildren from Nile Delta Governorates, Egypt: The Old World Highest Burdens Found in Lowlands

2021

Quantitative coprological analyses of children were performed in Alexandria and Behera governorates, Egypt, to ascertain whether individual intensities in the Nile Delta lowlands reach high levels as those known in hyperendemic highland areas of Latin America. Analyses focused on subjects presenting intensities higher than 400 eggs per gram of faeces (epg), the high burden cut-off according to WHO classification. A total of 96 children were found to shed between 408 and 2304 epg, with arithmetic and geometric means of 699.5 and 629.07 epg, respectively. Intensities found are the highest hitherto recorded in Egypt, and also in the whole Old World. A total of 38 (39.6%) were males and 58 (60.…

Microbiology (medical)Veterinary medicineOld WorldDiagnostic methodshigh intensitieshuman fascioliasisArticlechildrencoprologyparasitic diseasesQuantitative assessmentgeographical distributionImmunology and AllergyNile deltaMolecular BiologyFecesEggs per gramAlexandria and Behera governoratesNile DeltaGeneral Immunology and Microbiologygender and ageRPathogenicityInfectious DiseasesGeographyMedicineEgyptWho classificationPathogens
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The Effect of Pesticides on the Tomato Bacterial Speck Disease Pathogen Pseudomonas Syringae pv. Tomato

2020

A significant part of the used pesticides does not reach the target organisms and, while remaining in the agrophytocenosis, influences all living organisms in it. Having a toxic and often mutagenic effect, pesticides induce morphological and physiological changes in the cells of microorganisms and are the cause of phenotypic heterogeneity of their populations. However, the effect of pesticides on phytopathogenic bacteria as non-target microorganisms remains out of the field of view for most researchers. However, the use of pesticides can lead to expansion of the diversity of existing phytopathogens and, as a consequence, complications of identification of the pathogens, loss of resistance b…

MicroorganismMutant010501 environmental sciencesBiology01 natural scienceslcsh:TechnologyMicrobiologylcsh:Chemistry03 medical and health scienceschemistry.chemical_compoundmorphological dissociation<i>Pseudomonas syringae</i> pv. <i>tomato</i>antibacterial activityPseudomonas syringaeGeneral Materials ScienceInstrumentationPathogenlcsh:QH301-705.5030304 developmental biology0105 earth and related environmental sciencesFluid Flow and Transfer Processes0303 health sciencesaluminium phosethyllcsh:TProcess Chemistry and TechnologyfungiGeneral Engineeringfood and beveragesPseudomonas syringae pv. tomatopesticidesdeltamethrinPesticidebiology.organism_classificationlcsh:QC1-999Computer Science ApplicationsFungicideDeltamethrinchemistrylcsh:Biology (General)lcsh:QD1-999lcsh:TA1-2040mutagenic actionlcsh:Engineering (General). Civil engineering (General)Bacterialcsh:PhysicsApplied Sciences
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Clima subártico para os primeiros Homo sapiens na Europa

2021

Description

Mineralização do esmalte do denteSupplementary dataMultidisciplinaryEcologyFosfato ósseoSciAdv r-articlesTemperaturaSubarctic climateSocial and Interdisciplinary SciencesIsótopos de oxigênioDelta-O-18GeochemistryGeographyHuman evolutionComposição isotópica estávelHomo sapiensAnthropologyCavalosSérie-timeIngestão de águaÓsseo mamíferoResearch ArticleScience Advances
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Structure of Rhodococcus erythropolis limonene-1,2-epoxide hydrolase reveals a novel active site

2003

Epoxide hydrolases are essential for the processing of epoxide-containing compounds in detoxification or metabolism. The classic epoxide hydrolases have an alpha/beta hydrolase fold and act via a two-step reaction mechanism including an enzyme-substrate intermediate. We report here the structure of the limonene-1,2-epoxide hydrolase from Rhodococcus erythropolis, solved using single-wavelength anomalous dispersion from a selenomethionine-substituted protein and refined at 1.2 A resolution. This enzyme represents a completely different structure and a novel one-step mechanism. The fold features a highly curved six-stranded mixed beta-sheet, with four alpha-helices packed onto it to create a …

Models MolecularAFSG Stafafdelingen (WUATV)10050 Institute of Pharmacology and Toxicologydrug protein bindingEnantioselectivityEpoxide hydrolaseCrystallography X-Rayuncultured actinomyceteCatalytic Domain2400 General Immunology and Microbiologyalpha helixRhodococcuscholesterol epoxide hydrolasenaphthalene 12-dioxygenasedcl14limonene 12 epoxide hydrolaseEpoxide hydrolaseBacteria (microorganisms)delta(5)-3-ketosteroid isomeraseEpoxide HydrolasesLimonene-12-epoxide hydrolaseGeneral Neurosciencearticle2800 General NeuroscienceActinobacteria (class)Articlesagrobacterium-radiobacterEnzyme structureRecombinant Proteinsunclassified drugenzyme structurereaction analysisBiochemistrypriority journalenzyme active siteMechanism2-dioxygenaseDimerizationBiotechnologychemical reactioncrystal structureaspergillus-nigermacromolecular structuresStereochemistrybeta sheetvalpromideMolecular Sequence Data610 Medicine & healthGenetics and Molecular BiologyBiologyGeneral Biochemistry Genetics and Molecular BiologyBacterial Proteinssite directed mutagenesis1300 General Biochemistry Genetics and Molecular BiologyHydrolase1312 Molecular BiologyAmino Acid SequencedetoxificationRhodococcus erythropolisBiologyMonoterpene degradationMolecular Biologyprotein data-bankenzyme substrate complexEnzyme substrate complexnonhumancatalysisSequence Homology Amino AcidGeneral Immunology and Microbiologybacterial enzymeActive sitecrystal-structureAFSG Staff Departments (WUATV)enzyme metabolismProtein SubunitsenzymeEpoxide HydrolasesGeneral Biochemistrybiology.proteinMutagenesis Site-Directed570 Life sciences; biologyselenomethioninenaphthalene 1Alpha helix
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Mutations in the Bacillus thuringiensis Cry1Ca toxin demonstrate the role of domains II and III in specificity towards Spodoptera exigua larvae

2004

Several mutants of the Bacillus thuringiensis Cry1Ca toxin affected with regard to specific activity towards Spodoptera exigua were studied. Alanine was used to replace single residues in loops 2 and 3 of domain II (mutant pPB19) and to replace residues 541– 544 in domain III (mutant pPB20). Additionally, a Cry1Ca mutant combining all mutations was constructed (mutant pPB21). Toxicity assays showed a marked decrease in toxicity against S. exigua for all mutants, while they retained their activity against Manduca sexta, confirming the importance of these residues in determining insect specificity. Parameters for binding to the specific receptors in BBMV (brush border membrane vesicles) of S.…

Models MolecularMutantLaboratory of Virologyaminopeptidase nmedicine.disease_causeBiochemistrybrush-border membraneToxin oligomerizationSubstrate SpecificityBacterial toxin; Manduca sexta; Mode of action; Protoxin activation; Toxin oligomerization; Toxin receptor bindingHemolysin Proteinsmanduca-sextaBacillus thuringiensisheliothis-virescensAlanine:CIENCIAS DE LA VIDA::Bioquímica [UNESCO]MicrovillibiologyPRI BioscienceBiochemistryMode of actionLarvaThermodynamicsResearch ArticleProtein BindingBacterial Toxinspink-bollwormBacillus thuringiensisSpodopteraSpodopteraBinding CompetitiveManduca sextaLaboratorium voor VirologieBacterial ProteinsExiguamedicineirreversible bindingAnimalscrystal proteinsProtoxin activationProtein Structure QuaternaryMode of actionMolecular BiologyBacillus thuringiensis ToxinsToxin receptor bindingToxininsecticidal toxinpore formationCytoplasmic VesiclesfungiUNESCO::CIENCIAS DE LA VIDA::BioquímicaBacterial toxinCell Biologybiology.organism_classificationProtein Structure TertiaryEndotoxinsManduca sextaMutationcryia delta-endotoxins
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The NFκB-inducing kinase is essential for the developmental programming of skin-resident and IL-17-producing γδ T cells

2015

γδ T cells contribute to first line immune defense, particularly through their ability for rapid production of proinflammatory cytokines. The cytokine profile of γδ T cells is hard-wired already during thymic development. Yet, the molecular pathways underlying this phenomenon are incompletely understood. Here we show that signaling via the NFκB-inducing kinase (NIK) is essential for the formation of a fully functional γδ T cell compartment. In the absence of NIK, development of Vγ5+ dendritic epidermal T cells (DETCs) was halted in the embryonic thymus, and impaired NIK function caused a selective loss of IL-17 expression by γδ T cells. Using a novel conditional mutant of NIK, we could show…

MouseT-Lymphocytes10263 Institute of Experimental ImmunologyInterleukin 210302 clinical medicineT-Lymphocyte Subsets2400 General Immunology and MicrobiologyCytotoxic T cellIL-2 receptorBiology (General)0303 health sciencesGeneral NeuroscienceZAP70Interleukin-17QR2800 General NeuroscienceCell DifferentiationReceptors Antigen T-Cell gamma-deltaGeneral MedicineNatural killer T cell3. Good healthCell biologymedicine.anatomical_structureMedicineSignal TransductionResearch ArticleQH301-705.5T cellScienceImmunology610 Medicine & healthProtein Serine-Threonine KinasesBiologyγδ T cellsGeneral Biochemistry Genetics and Molecular Biology03 medical and health sciences1300 General Biochemistry Genetics and Molecular BiologymedicineAnimalsAntigen-presenting cell030304 developmental biologyGeneral Immunology and MicrobiologyNIKT cell developmentT cell cytokine productionthymic stromaMice Inbred C57BLDevelopmental Biology and Stem CellsImmunology570 Life sciences; biology030215 immunologyeLife
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Evaluation of the polarization observables I-S and I-C in the reaction gamma p -> pi(0)eta p

2010

We evaluate the polarization observables I(S) and I(C) for the reaction gamma p -> pi(0)eta p, using a chiral unitary framework developed earlier. The I(S) and I(C) observables have been recently measured for the first time by the CBELSA/TAPS Collaboration. The theoretical predictions of I(S) and I(C), given for altogether 18 angle-dependent functions, are in good agreement with the measurements. Also, the asymmetry d Sigma/dcos theta evaluated here agrees with the data. We show the importance of the Delta(1700) D(33)-resonance and its S-wave decay into eta Delta(1232). The result can be considered as a further confirmation of the dynamical nature of this resonance. At the highest energies,…

Nuclear Theorypolarized beam [photon]Físicaphoton p --> p eta pi0Delta(1232)Delta(1940)chiralexclusive reaction [photon p]asymmetry [polarization]unitarityddc:530angular distributionhadronic decay [Delta(1700)]numerical calculationsNuclear Experiment
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Detection of charged pions and protons in the segmented electromagnetic calorimeter TAPS

1998

We present the characteristics of the segmented BaF2 calorimeter TAPS for the measurement of charged pions and protons. The method of particle identification exploits the relation between the kinetic energy of a particle, its mass and the time-of-flight required to reach the detector. The detection efficiency is calculated using GEANT-GCALOR simulations. The analysis method is applied in the reaction Ar-40 + Ca-nat at 0.8A GeV. The simultaneous detection of charged pions and protons can be used to search for correlated pairs signalling the de-excitation of the Delta(1232) resonance. (C) 1998 Elsevier Science B.V. All rights reserved.

Nuclear and High Energy PhysicsPhotonBAF2 SCINTILLATORSHEAVY-ION COLLISIONSPHOTONSKinetic energy01 natural sciencesResonance (particle physics)Particle identificationENERGYNuclear physicsPion0103 physical sciencesABSORPTIONPARTICLESNuclear Experiment010306 general physicsInstrumentationcharged pion detectionPhysicsDelta(1232) resonance detectionCalorimeter (particle physics)010308 nuclear & particles physicsDetectorproton detection[PHYS.HPHE]Physics [physics]/High Energy Physics - Phenomenology [hep-ph]ParticleHigh Energy Physics::ExperimentAtomic physics
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Proton Direct Ionization Upsets at Tens of MeV

2023

Experimental monoenergetic proton single-event upset (SEU) cross sections of a 65-nm low core-voltage static random access memory (SRAM) were found to be exceptionally high not only at low energies ($ 3 MeV and extending up to tens of MeV. The SEU cross Section from 20-MeV protons exceeds the 200-MeV proton SEU cross Section by almost a factor of 3. Similarly, monoenergetic neutron cross sections at 14 MeV are about a factor of 3 lower than the 20-MeV proton cross section. Because of Monte Carlo (MC) simulations, it was determined that this strong enhancement is due to the proton direct ionization process as opposed to the elastic and inelastic scattering processes that dominate the SEU res…

Nuclear and High Energy Physicsprotonitprotonsionitionisoiva säteilyscatteringneutronsenergiansiirtoMonte-Carlo simulationsneutronitmuistit (tietotekniikka)proton direct ionizationMonte Carlo -menetelmätNuclear Energy and Engineeringrandom access memorytrajectorydelta-raysNuclear Physics - Experimentsingle event upsetsElectrical and Electronic Engineeringliike-energia
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Nuclear pion photoproduction in theΔresonance region

1999

A measurement of the /sup 12/C( gamma , pi /sup +/n)/sup 11/B reaction in quasifree pi -production kinematic regimes has been performed using tagged photons in conjunction with large solid angle pi and n detectors. The aim of the experiment was to investigate predicted modifications to the Delta excitation of nucleons and their subsequent propagation and decay, brought about by the nuclear medium. Differential cross sections are presented for photon energies spanning the Delta (1232) excitation region. The measurements are consistent with distorted wave impulse approximation calculations in which the amplitude for proton Delta excitation, followed by Delta propagation and decay to pi /sup +…

Nuclear physicsPhysicsDeltaNuclear and High Energy PhysicsPionAmplitudePhotonSolid angleImpulse (physics)Atomic physicsNucleonExcitationPhysical Review C
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