Search results for "Deme"

Periodontitis and alzheimer´s disease

2020

Background Alzheimer's disease (AD), the main cause of dementia in the adult population, is characterized by a progressive loss of cognitive function. It is considered that neuroinflammation plays a fundamental role in its onset and progression. The bacteria present in the disbiotic microbiome generated during the course of periodontitis (PE) are capable of inducing a systemic inflammatory response, exacerbating the production of proinflammatory mediators that have the potential to spread to the systemic circulation. Material and Methods A literature review was made using the databases Scielo, PubMed, EBSCO and key words "Alzheimer disease", "Periodontitis", "Neurodegeneration", "Inflammati…

Identification of three novel progranulin mutations in a series of patients affected by sporadic and familial frontotemporal lobar de generation. Pla…

2009

Physical activity as a protective factor for dementia and Alzheimer’s disease: systematic review, meta-analysis and quality assessment of cohort and …

2022

ObjectivePhysical activity (PA) is associated with a decreased incidence of dementia, but much of the evidence comes from short follow-ups prone to reverse causation. This meta-analysis investigates the effect of study length on the association.DesignA systematic review and meta-analysis. Pooled effect sizes, dose–response analysis and funnel plots were used to synthesise the results.Data sourcesCINAHL (last search 19 October 2021), PsycInfo, Scopus, PubMed, Web of Science (21 October 2021) and SPORTDiscus (26 October 2021).Eligibility criteriaStudies of adults with a prospective follow-up of at least 1 year, a valid cognitive measure or cohort in mid-life at baseline and an estimate of the…

Iäkkäiden henkilöiden kognitiivisen heikentymisen varhainen tunnistaminen psykometrisin ja neuropsykologisin testein

2001

Dementia in former amateur and professional contact sports participants : population-based cohort study, systematic review, and meta-analysis

2023

Background Although there is growing evidence that former professional athletes from sports characterised by repetitive head impact subsequently experience an elevated risk of dementia, the occurrence of this disorder in retired amateurs, who represent a larger population, is uncertain. The present meta-analysis integrates new results from individual-participant analyses of a cohort study of former amateur contact sports participants into a systematic review of existing studies of retired professionals and amateurs. Methods The cohort study comprised 2005 male retired amateur athletes who had competed internationally for Finland (1920–1965) and a general population comparison group of 1386 …

Muliggjør GPS et friere og tryggere liv med demens i familien? : pårørende til personer med demens som benytter GPS-teknologi -Erfaringer og utfordri…

2016

Masteroppgave i helse- og sosialinformatikk- Universitetet i Agder, 2016 According to statistics, there will be an increasing number of elderly people and people with dementia in the future. The importance of the relatives are being emphasized as an increasing resource in developing the public health care and caring services in the municipality and many of them contribute with an outstanding effort helping their closest family members. These persons can be important contributors for the person with dementia, in such a way that the person is able to continue with an active and purposeful life in their own home. Welfare technology exists as one of the devices to support that. Based on that it…

Physical activity may not be associated with long‐term risk of dementia and Alzheimer’s disease

2021

Background While it is well established that physical activity is associated with reduced risk of vascular and non‐vascular outcomes as well as mortality, evidence on the association between physical activity and dementia is inconsistent. We aimed to assess the associations of physical activity with the risk of dementia and Alzheimer’s disease (AD). Material and methods We analysed data on 2,394 apparently healthy men with good baseline cognitive function from the prospective population‐based Kuopio Ischaemic Heart Disease study. We assessed habits of physical activity at baseline using a 12‐month leisure‐time physical activity (LTPA) questionnaire. Using Cox regression, we calculated hazar…

Epilepsy in neuropathologically verified Alzheimer's disease

2018

Purpose Subjects with Alzheimer’s disease (AD) have been shown to be at a higher risk for epilepsy. The vast majority of the previous studies have not included a full neuropathological examination. Methods The objective of this study was to assess the prevalence of epilepsy and clinicopathological characteristics in a well-defined study group of 64 subjects with AD. We evaluated the clinicopathological findings in 64 subjects (mean age at death 85 ± 8.6 years) from a longitudi-nal study cohort of patients with dementia. Results Eleven out of the 64 subjects (17%) had a history of epilepsy, which is comparable to previous studies. The subjects with AD and epilepsy were significantly younger …

Kotilomituspalvelu omaishoitajan ja dementoituneen läheisen kotihoidon tukena : omaishoitajien kokemuksia kotilomituspalvelusta dementoituneen läheis…

2000

Generatividad, trayectorias y ganancias de los cuidadores de personas con demencia: variables predictoras y relación con las consecuencias del cuidado

2016

La situación de provisión de cuidados a una persona con demencia ha tendido a ser estudiada desde una perspectiva exclusivamente negativa que enfatiza en los problemas con los que se pueden encontrar los cuidadores informales y las consecuencias de cuidar. No obstante, algunos autores sugieren que este planteamiento contribuye a dar una imagen reduccionista y sesgada del fenómeno del cuidado informal, y que para obtener una visión más completa del mismo y diseñar intervenciones más efectivas para incrementar el bienestar de los cuidadores sería recomendable tener en cuenta el papel de algunas variables de corte más positivo. Mediante esta tesis se pretende dar un paso adelante en esta direc…