Search results for "Design"

showing 10 items of 5885 documents

“I am cobalt” Thérèse Moll

2020

Thérèse Moll (1934 - 1961), a little known but by no means secondary figure, is part of the history of visual communication design in which she left a brief but lasting trace. Moll is enrolled at the School of Arts and Crafts in Basel where she meets important designers and teachers including Armin Hoffman, Emil Ruder, Karl Gerstner and Antonio Boggeri. Still very young, she receives an invitation to be a visiting designer at MIT in Boston. At the beginning of 1959, Thérèse Moll arrives in the U.S.A. and during her four-month stay she works with Jacqueline S. Casey and Ralph Coburn at MIT’s Office of Publications, radically modifying the MIT communication, while at the same time introducing…

Thérèse Moll history of visual communication design MIT Boston Swiss schoolSettore ICAR/13 - Disegno Industriale
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Software tools for using a personal computer as a timer device to assess human kinematic performance: a case study.

1995

Frequently, the assessment of the physical condition of a sportsman depends on the evaluation of different tests, based on biomechanical performance. The data acquisition in these tests is usually hand made, because its automatization is difficult. But when movements are constrained by means of their specific nature, simple tools can be used to achieve that data acquisition. In this paper, a simple and inexpensive system is described to make use of the timing capabilities of a personal computer (PC) to use it as a timer, with applications in biomechanics and sport training. The data acquisition method is based on a PC that, using a specific programming dealing with event timing, gets signal…

Time FactorsAnaerobic ThresholdComputer scienceMovementSoftware ValidationHealth InformaticsKinematicsSports MedicineData acquisitionSoftwareMicrocomputersHumansSimulationbusiness.industryEvent (computing)ComputersReproducibility of ResultsComputer Science ApplicationsBiomechanical PhenomenaPersonal computerExercise TestSoftware designTimerbusinessParallel portSoftwareAlgorithmsComputer methods and programs in biomedicine
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Caspase-3 contributes to ZO-1 and Cl-5 tight-junction disruption in rapid anoxic neurovascular unit damage.

2011

BACKGROUND: Tight-junction (TJ) protein degradation is a decisive step in hypoxic blood-brain barrier (BBB) breakdown in stroke. In this study we elucidated the impact of acute cerebral ischemia on TJ protein arrangement and the role of the apoptotic effector protease caspase-3 in this context. METHODOLOGY/PRINCIPAL FINDINGS: We used an in vitro model of the neurovascular unit and the guinea pig whole brain preparation to analyze with immunohistochemical methods the BBB properties and neurovascular integrity. In both methodological approaches we observed rapid TJ protein disruptions after 30 min of oxygen and glucose deprivation or middle cerebral artery occlusion, which were accompanied by…

Time FactorsAnatomy and Physiologylcsh:MedicineMiceMolecular Cell BiologyPathologySignaling in Cellular ProcessesHypoxia Brainlcsh:ScienceCells CulturedNeuropathologyApoptotic SignalingMultidisciplinaryTight junctionCaspase 3ChemistryAnimal ModelsCell biologyTransport proteinProtein Transportmedicine.anatomical_structureNeurologyBlood-Brain BarrierMedicineResearch ArticleSignal TransductionClinical Research DesignCerebrovascular DiseasesGuinea PigsIschemiaContext (language use)Caspase 3Protein degradationBlood–brain barrierNeurological SystemTight JunctionsCapillary PermeabilityModel OrganismsDiagnostic MedicinemedicineAnimalsTransient Ischemic AttacksAnimal Models of DiseaseClaudinBiologyIschemic Strokelcsh:REndothelial CellsMembrane ProteinsPhosphoproteinsmedicine.diseaseAnatomical PathologyClaudinsImmunologyZonula Occludens-1 ProteinNervous System Componentslcsh:QPLoS ONE
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Benefits of solvent concentration pulses in retention time modelling of liquid chromatography

2019

The advantages and disadvantages of the use of isocratic experimental designs including transient increments of organic solvent (i.e., pulses) in the mobile phase(s) of lowest elution strength are explored with modelling purposes. For retained solutes, this type of mixed design offers similar or better predictive capability than gradient designs, shorter measurement time than pure isocratic designs, and retention model parameters that agree with those derived from pure isocratic experiments, with similar uncertainties. The predicted retention times are comparable to those offered by models adjusted from pure isocratic designs, and the solvent waste is appreciably lower. Under a practical st…

Time FactorsChromatographyChemistryElutionDesign of experiments010401 analytical chemistryOrganic ChemistryGeneral Medicine010402 general chemistry01 natural sciencesBiochemistryHigh-performance liquid chromatographyIntegral equation0104 chemical sciencesAnalytical ChemistryPulse (physics)Numerical integrationSolventModels ChemicalPhase (matter)SolventsChromatography LiquidJournal of Chromatography A
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Supercritical carbon dioxide extraction of seed oil from yellow horn (Xanthoceras sorbifolia Bunge.) and its anti-oxidant activity

2010

Supercritical fluid carbon dioxide (SF-CO(2)) extraction (SFE) of seed oil from yellow horn and its anti-oxidant activity were investigated. The effects of CO(2) flow rate and particle size were firstly optimized, and a central composite design (CCD) combined with response surface methodology was used to study the effects of extraction pressure, temperature and time on the extraction yields. A maximal extraction yield of 61.28% was achieved under optimal conditions of extraction pressure 30 MPa at 45.68 degrees C, 2.08 h and CO(2) flow rate 12 kg/h with 0.5mm particle size. By analyzing the chemical composition of the seed oil, we found that the content of unsaturated fatty acids was approx…

Time FactorsEnvironmental EngineeringCentral composite designSurface PropertiesDPPHBioengineeringAntioxidantschemistry.chemical_compoundSapindaceaePicratesPlant OilsOrganic chemistryParticle SizeWaste Management and DisposalChromatographySupercritical carbon dioxideRenewable Energy Sustainability and the EnvironmentBiphenyl CompoundsFatty AcidsExtraction (chemistry)General MedicineCarbon Dioxidebeta CaroteneSupercritical fluidBiphenyl compoundVegetable oilchemistrySeedsCarbon dioxideRheologyBiotechnologyBioresource Technology
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Comparison between hybrid moving bed biofilm reactor and activated sludge system: a pilot plant experiment

2010

The paper presents the comparison between the traditional activated sludge system (AS) and a hybrid moving bed biofilm reactor (HMBBR). In particular, an experimental campaign has been carried out at the WWTP in Palermo (Italy), on a pilot plant consisting of two pre-anoxic schemes. The aerated tank of the HMBBR line was filled with suspended carriers (AnoxKaldnes™ K1), with a 30% filling ratio. The hydraulic load of the HMBBR line was increased up to two times the AS one. Further, in order to distinguish the additional contribution of the attached biomass for the HMBBR system, in the two lines the Mixed Liquor Suspended Solids (MLSS) was maintained as equal as possible. The monitoring peri…

Time FactorsEnvironmental EngineeringNitrogenhybrid biofilm reactorPilot ProjectsHMBBRWaste Disposal Fluidmunicipal wastewaterWater PurificationBioreactorsorganic and nitrogen loadbiological treatmentOrganic ChemicalsWater Science and TechnologySettore ICAR/03 - Ingegneria Sanitaria-AmbientaleSewageMoving bed biofilm reactorSettore ICAR/02 - Costruzioni Idrauliche E Marittime E IdrologiaEnvironmental engineeringEquipment DesignnitrificationCarbonMixed liquor suspended solidsQuaternary Ammonium CompoundsWaste treatmentActivated sludgePilot plantItalyWastewaterBiofilmsEnvironmental scienceSewage treatmentWater Pollutants ChemicalWaste disposalWater Science and Technology
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Acoustic methods for measuring the porosities of porous materials incorporating dead-end pores

2013

International audience; The acoustic properties of porous materials containing dead-end (DE) pores have been proposed by Dupont et al. [J. Appl. Phys. 110, 094903 (2011)]. In the theoretical description, two physical parameters were defined (the dead-end porosity and the average length of the dead-end pores). With the knowledge of the open porosity (measured with non-acoustic methods), and the measurement of kinematic porosity (also called the Biot porosity in this article), it is possible to deduce the dead-end porosity. Two acoustic methods for measuring the Biot porosity for a wide range of porosities are proposed. These methods are based on acoustic transmission and on the low and high …

Time FactorsMaterials scienceAcoustics and Ultrasonics02 engineering and technologyLow frequency01 natural sciencesMotionViscosityBiot porosityArts and Humanities (miscellaneous)0103 physical sciencesPressureComputer SimulationUltrasonicsTransmission coefficientComposite materialPorosity010301 acoustics[ PHYS.MECA.ACOU ] Physics [physics]/Mechanics [physics]/Acoustics [physics.class-ph][SPI.ACOU]Engineering Sciences [physics]/Acoustics [physics.class-ph]Biot numberViscosity[ SPI.ACOU ] Engineering Sciences [physics]/Acoustics [physics.class-ph]transmission tubeReproducibility of ResultsSignal Processing Computer-AssistedAcousticsEquipment DesignModels Theoretical021001 nanoscience & nanotechnology[PHYS.MECA.ACOU]Physics [physics]/Mechanics [physics]/Acoustics [physics.class-ph]SoundUltrasonic sensorPhase velocity0210 nano-technologyPorous mediumPorosityporous materials
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Minimal exposure time of different LED-curing devices

2007

Abstract Objectives The purpose of the study was to investigate the shortest possible exposure time of different LED-curing devices for five different resin composites in a clinically relevant in vitro-model, where a 7 mm distance from the light guide tip to the bottom side of the cavity was compiled. Methods Resin composite samples (Tetric EvoCeram A3, Filtek Supreme XT A3B, Premise A3, CeramX Mono M5, QuiXfil) were filled in three increments of 2 mm thickness each in stainless steel moulds (O = 5 mm, h  = 6 mm, n  = 9). The samples were incrementally exposed to different blue LED-curing devices (Bluephase, Bluephase C8, Bluephase 16i/Ivoclar Vivadent, L.E.Demetron II/sds Kerr, Elipar Free…

Time FactorsMaterials scienceLightSurface PropertiesHardness ratioResin compositeComposite numberLight guideEquipment DesignComposite ResinsHardnessTetric EvoCeramDental MaterialsReference sampleHardnessMechanics of MaterialsMaterials TestingHumansGeneral Materials ScienceComposite materialGeneral DentistryLightingCuring (chemistry)Dental Materials
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Use of semipermeable membrane devices for monitoring pesticides in indoor air.

2009

Abstract In this work, 40 pesticides from different categories were analyzed in the air of 20 indoor places that have an intensive use of pesticides. Passive sampling was carried out by using semipermeable membrane devices (SPMDs) deployed for 7 days. SPMDs were analyzed using microwave-assisted extraction and GC/MS. PCB-195 was used as an internal standard. Recoveries ranged between 81 and 108 for many compounds, with RSD values <11. Typical LOD values for 7 days of sampling were from 0.1 to 3.1 ng/m. Propamocarb, propoxur, carbosulfan, pirimicarb, metribuzin, metalaxyl, pendimethalin, oxadiazon, phenothrin, and permethrin were detected in 11 sampling sites, with air concentrations …

Time FactorsPirimicarbChemistry Techniques AnalyticalGas Chromatography-Mass SpectrometryPermeabilityAnalytical Chemistrychemistry.chemical_compoundmedicineEnvironmental ChemistryPesticidesPharmacologyAir PollutantsPesticide residueReproducibility of ResultsMembranes ArtificialEquipment DesignPesticidePropoxurModels TheoreticalchemistryEnvironmental chemistryAir Pollution IndoorCalibrationPropamocarbCarbosulfanPhenothrinAgronomy and Crop ScienceFood SciencePermethrinmedicine.drugEnvironmental MonitoringJournal of AOAC International
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The Hip Fracture Surgery in Elderly Patients (HIPELD) study: protocol for a randomized, multicenter controlled trial evaluating the effect of xenon o…

2012

Trials 13, 180 (2012). doi:10.1186/1745-6215-13-180

Time FactorsXenonCost-Benefit AnalysisMedicine (miscellaneous)Hospital CostHip fracturelaw.inventionStudy ProtocolFracture Fixation InternalRandomized controlled triallawFracture fixationAge FactorPharmacology (medical)Prospective StudiesHospital CostsProspective cohort studylcsh:R5-920Hip fractureDrug CostIncidence (epidemiology)Age FactorsPostoperative deliriumPsychiatric Status Rating ScaleEuropeTreatment OutcomeResearch DesignAnesthesiaAnesthetics Inhalationmedicine.symptomlcsh:Medicine (General)Humanmedicine.drugMethyl Ethersmedicine.medical_specialtyTime FactorDrug CostsSevofluraneSevofluranemedicineHumansCost-Benefit AnalysiAgedPsychiatric Status Rating ScalesHip Fracturesbusiness.industryDeliriummedicine.diseaseSurgeryClinical trialProspective StudieMethyl EtherDeliriumbusinessTrials
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