Search results for "Design"

showing 10 items of 5885 documents

Modular Breath Analyzer (MBA): Introduction of a Breath Analyzer Platform Based on an Innovative and Unique, Modular eNose Concept for Breath Diagnos…

2021

Exhaled breath analysis for early disease detection may provide a convenient method for painless and non-invasive diagnosis. In this work, a novel, compact and easy-to-use breath analyzer platform with a modular sensing chamber and direct breath sampling unit is presented. The developed analyzer system comprises a compact, low volume, temperature-controlled sensing chamber in three modules that can host any type of resistive gas sensor arrays. Furthermore, in this study three modular breath analyzers are explicitly tested for reproducibility in a real-life breath analysis experiment with several calibration transfer (CT) techniques using transfer samples from the experiment. The experiment …

calibration transferComputer scienceRespiratory SystemPharmaceutical ScienceOrganic chemistrycorrelation alignment01 natural scienceseNoseAnalytical Chemistry0302 clinical medicineQD241-441DDC 570 / Life sciencesDrug Discoverybreath analysisSensortechnikdigestive oral and skin physiologyAtemgasanalyseMischoxideExhalationChemistry (miscellaneous)piecewise direct standardization030220 oncology & carcinogenesisElektronische NaseCalibrationMolecular MedicineMOX sensorsSpectrum analyzerAdolescentlow sensing chamber volumeReal-time computingstandard samplesbreath samplingArticleElectronic nose03 medical and health sciencesddc:570Breath testsCalibrationHumansddc:610Physical and Theoretical ChemistryReproducibilitybusiness.industry010401 analytical chemistryBreath samplingpattern recognitionBreath diagnosticsAtemluftModular design0104 chemical sciencesBreath analyzerBreath gas analysisbusinessBiosensing techniquesDDC 610 / Medicine & healthBiomarkersMolecules
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Advances in Targeting Signal Transduction Pathways

2012

// James A. McCubrey 1 , Linda S. Steelman 1 , William H. Chappell 1 , Lin Sun 1,2 , Nicole M. Davis 1 , Stephen L. Abrams 1 , Richard A. Franklin 1 , Lucio Cocco 3 , Camilla Evangelisti 4 , Francesca Chiarini 4 , Alberto M. Martelli 3,4 , Massimo Libra 5 , Saverio Candido 5 , Giovanni Ligresti 5 , Grazia Malaponte 5 , Maria C. Mazzarino 5 , Paolo Fagone 5 , Marco Donia 5 , Ferdinando Nicoletti 5 , Jerry Polesel 6 , Renato Talamini 6 , Jorg Basecke 7 , Sanja Mijatovic 8 , Danijela Maksimovic-Ivanic 8 , Michele Milella 9 , Agostino Tafuri 10 , Joanna Dulinska-Litewka 11 , Piotr Laidler 11 , Antonio B. D’Assoro 12 , Lyudmyla Drobot 13 , Kazuo Umezawa 14 , Giuseppe Montalto 15 , Melchiorre Cer…

cancer stem cellsAMPKtherapy resistanceReviewsLibrary scienceAntineoplastic AgentsrafBiologyPI3Kampk03 medical and health sciences0302 clinical medicineCANCER STEM CELLSNeoplasmsAnimalsHumansUniversity medicalMolecular Targeted TherapyAkt; AMPK; Cancer stem cells; Metformin; MTOR; PI3K; Raf; Targeted therapy; Therapy resistanceTreatment resistanceProtein Kinase Inhibitors030304 developmental biology0303 health sciencesRoswell Park Cancer InstituteAktCancer stem cellAKTMTORAMP-ACTIVATED PROTEIN KINASE (AMPK)Raftargeted therapyMetformin3. Good healthGene Expression Regulation NeoplasticCell stressOncologyDrug Resistance NeoplasmDrug Designtargeted therapy; metformin; therapy resistance; pi3k; akt; ampk; cancer stem cells; raf; mtor030220 oncology & carcinogenesisMutationmTORMolecular targetsCancer researchmetforminSignal Transduction
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A hardware skin-segmentation IP for vision based smart ADAS through an FPGA prototyping

2017

International audience; In this paper we presents a platform based design approach for fast HW/SW embedded smart Advanced Driver Assistant System (ADAS) design and prototyping. Then, we share our experience in designing and prototyping a HW/SW vision based smart embedded system as an ADAS that helps to increase the safety of car's drivers. We present a physical prototype of the vision ADAS based on a Zynq FPGA. The system detects the fatigue state of the driver by monitoring the eyes closure and generates a real-time alert. A new HW/SW codesign skin segmentation step to locate the eyes/face is proposed. Our presented new approach migrates the skin segmentation step from processing system (S…

car driver safetyComputer scienceautomotive electronicsFPGA Prototyping02 engineering and technology01 natural sciencesIP networkshardware skin segmentation IPhardware-software vision based smart embedded system[SPI]Engineering Sciences [physics]HardwareHigh-level synthesis0202 electrical engineering electronic engineering information engineeringSegmentationField-programmable gate arrayimage segmentationSkinfield programmable gate arraysVision basedbusiness.industry010401 analytical chemistryVehiclesobject detectionplatform based design0104 chemical sciences[SPI.TRON]Engineering Sciences [physics]/ElectronicsProgrammable logic devicedriver information systemsimage recognitionStreaming mediaembedded smart advanced driver assistant systemEmbedded systemFacefatigue state detectionPlatform-based design020201 artificial intelligence & image processingembedded systemsState (computer science)vision based smart ADASbusinesshardware-software codesignroad safetyComputer hardwareSoftwareFPGA prototype
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The caramel flavour: impacts of the volatile and the non-volatile fraction on perception

2013

The aim of this thesis was to investigate the impact of the volatile odorant fraction and the non-volatile fraction on the perception of caramel flavour. The first step focused on the analytical characterization of the volatile odorant fraction of caramel using Gas Chromatography coupled to Olfactometry (GC/O), GC/Mass Spectrometry (GC/MS) and heart-cutting MDGC/MS/O. Results highlighted the presence of more than one hundred compounds and demonstrated the complexity of the caramel volatile fraction. The objective of the second step was to understand the contribution of odorant compounds identified to the caramel aroma typicality. Literature shows that odour intensity is not sufficient to ev…

caramelheart-cuttinginteractionsrecombinationflavoursensory analysisaddition testin-vitro aroma release[SDV.AEN] Life Sciences [q-bio]/Food and Nutritionaromagas-chromatographyomission testAnalyse sensoriellefactorial designodourarome[SDV.BBM] Life Sciences [q-bio]/Biochemistry Molecular Biologyflaveurodeur
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ELEMENTO POLIFUNZIONALE DI ARREDO

2009

Il design brevettato rientra nella categoria di arredi per strutture educative destinate a bambini di età compresa tra 1 e 3 anni. L'arredo consta di due elementi indipendenti e componibili, realizzati in cartone riciclato, che possono assumere alternativamente la configurazione di poltrona e scrittoio con seduta.

cartonechildbambinodesignArredo polifunzionaleasilopoltronachaireco-designindustrial designSettore ICAR/13 - Disegno Industrialericiclabile.tableCardboardrecyclable.
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Regole per costruire in campagna

2014

Il saggio illustra l'esperienza didattica di un Laboratorio di Progettazione di primo anno del Corso di Laurea in Architettura della Università di Palermo il cui docente è Michele Sbacchi. Il tema affrontato è il progetto di una casa unifamiliare nella campagna. La didattica è sviluppata in modo da fare scaturire il progetto come un ragionamento a partire dalla osservazione del contesto, nella presupposizione di uno scopo. La didattica è quindi improntata a indurre a una procedura corretta piuttosto che al confezionamento di un prodotto. I progetti svolti individualmente, mettono in scena rigore compositivo e completa derivazione dal contesto. Description of first-year architectural design …

casa unifamiliare didattica primo anno architetturasingle-family house first-year design studioSettore ICAR/14 - Composizione Architettonica E Urbana
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Aktivitāšu izstrāde nozares angļu valodas apguvei

2019

Lai saglabātu konkurētspēju savā jomā, profesionāļiem ir jāattīsta jomai atbilstošu angļu valodas zināšanu apguve, bet aizvien pieaugošais pieprasījums pēc nozaru angļu valodas apmācībām rada pieprasījumu arī pēc kompetentiem pasniedzējiem un mācību materiāla izstrādātājiem. Šis darbs tika izstrādāts ar mērķi pētīt nozaru angļu valodas mācību materiālu izveides procesu, kā arī, apmācot studentus, radīt oriģinālu mācību materiālu konkrētai Finanšu menedžmenta programmas studentu grupai. Lai izveidotu šo materiālu, tika iegūti kvalitatīvie dati, analizējot nodarbību laikā novērotos procesus. Jaunizveidotais materiāls tika veiksmīgi izmantots praksē.

case studyValodniecībateacher reflectionEnglish for Specific Purposes (ESP)activity designrole-play
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Chemical design of coordination polymers and functional materials: from pore control in MOFs through spin dynamics in nanomagnets to rotaxanes in mol…

2022

El trabajo de esta tesis se enmarca en el diseño químico de polímeros de coordinación y de materiales funcionales para poder ser utilizados en el campo de los materiales moleculares. El capítulo 1 ofrece una visión de los avances más significativos en la química de coordinación, así como una introducción general de los materiales moleculares más relevantes en la actualidad. El objetivo es proporcionar al lector el conocimiento necesario para establecer las bases sobre los campos a tratar. El resto de capítulos está organizado de acuerdo con un aumento de la dimensionalidad, empezando con moléculas discretas y terminando con polímeros de coordinación. El capítulo dos describe dos estructuras…

catalysismolecular electronicsUNESCO::QUÍMICAchemical designmolecular switchesgas separationMOFsSMM
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Computer Vision Interaction for People with Severe Movement Restrictions

2006

In this paper we present the starting point of research in applying humancomputer interaction (HCI) techniques to help people with cerebral palsy to use computers via vision-based interaction. Our work includes the development and improvement of visionbased assistive technology, which was tested in experiments with cerebral palsy users. A brief review of current assistive technologies for severely physically impaired people and an explanation of the developed applications of such technologies are also presented. The final part of the paper describes the experimentation goals, process, and preliminary results. Future work directions are also indicated.

cerebral palsycomputer vision interactionhuman-computer interactiondesign for allComputingMilieux_COMPUTERSANDSOCIETYphysically disabled usersaccessibility
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A synthetic hexapeptide (Argireline) with antiwrinkle activity

2008

Botulinum neurotoxins (BoNTs) represent a revolution in cosmetic science because of their remarkable and long-lasting antiwrinkle activity. However, their high neurotoxicity seriously limits their use. Thus, there is a need to design and validate non-toxic molecules that mimic the action of BoNTs. The hexapeptide Ac-EEMQRR-NH2 (coined Argireline) was identified as a result of a rational design programme. Noteworthy, skin topography analysis of an oil/water (O/W) emulsion containing 10% of the hexapeptide on healthy women volunteers reduced wrinkle depth up to 30% upon 30 days treatment. Analysis of the mechanism of action showed that Argireline significantly inhibited neurotransmitter relea…

chemistry.chemical_classificationAgingRational designNeurotoxicityPharmaceutical SciencePeptideDermatologymedicine.diseaseExocytosisColloid and Surface ChemistryMechanism of actionchemistryBiochemistryChemistry (miscellaneous)In vivoDrug DiscoveryToxicitymedicineNeurotoxinmedicine.symptomInternational Journal of Cosmetic Science
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