Search results for "Development"

showing 10 items of 26949 documents

Constitutive Activation of the Midgut Response to Bacillus thuringiensis in Bt-Resistant Spodoptera exigua

2010

Bacillus thuringiensis is the most effective microbial control agent for controlling numerous species from different insect orders. The main threat for the long term use of B. thuringiensis in pest control is the ability of insects to develop resistance. Thus, the identification of insect genes involved in conferring resistance is of paramount importance. A colony of Spodoptera exigua (Lepidoptera: Noctuidae) was selected for 15 years in the laboratory for resistance to Xentari (TM), a B. thuringiensis-based insecticide, reaching a final resistance level of greater than 1,000-fold. Around 600 midgut ESTs were analyzed by DNA-macroarray in order to find differences in midgut gene expression …

0106 biological sciencesDrug Resistancelcsh:MedicineGene ExpressionInsectaminopeptidase n01 natural sciencesAminopeptidasesHemolysin ProteinsEndotoxinmanduca-sextaBacillus thuringiensisInsect ProteinBiotechnology/Applied Microbiologylcsh:Scienceheliothis-virescensmedia_common0303 health sciencesLarvaMultidisciplinarybiologymediated insect resistanceGenetics and Genomics/Gene ExpressionEcology/Population Ecologybacterial-infectionNoctuidaeInsect ProteinsResearch Articlemedia_common.quotation_subjectAminopeptidaseMolecular Sequence DataBacillus thuringiensisBacterial ProteinSpodopteraSpodopterastem-cell proliferationMicrobiology03 medical and health sciencesMicrobiology/Applied MicrobiologyBacterial ProteinsExiguaBotanyBacillus thuringiensiAnimalscrystal proteinsBIOS Plant Development SystemsAmino Acid Sequencekinase pathways030304 developmental biologyposterior midgutHeliothis virescensBacillus thuringiensis ToxinsAnimaltrichoplusia-nilcsh:RfungiMidgutHemolysin Proteinbiology.organism_classificationEndotoxinsGastrointestinal Tract010602 entomologyPlant Biology/Agricultural Biotechnologylcsh:QSequence Alignment
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Collateral sensitivity of natural products in drug-resistant cancer cells

2018

Cancer chemotherapy is frequently hampered by drug resistance. Concepts to combine anticancer drugs with different modes of action to avoid the development of resistance did not provide the expected success in the past, because tumors can be simultaneously non-responsive to many drugs (e.g. the multidrug resistance phenotype). However, tumors may be specifically hypersensitive to other drugs - a phenomenon also termed collateral sensitivity. This seems to be a general biological mechanism, since it also occurs in drug-resistant Escherichia coli and Saccharomyces cerevisiae. Here, we give a timely and comprehensive overview on hypersensitivity in resistant cancer cells towards natural produc…

0106 biological sciencesDrugmedicine.drug_classmedia_common.quotation_subjectAntibioticsAntineoplastic AgentsDrug Collateral SensitivityBioengineeringDrug resistance01 natural sciencesApplied Microbiology and Biotechnology03 medical and health sciencesNeoplasms010608 biotechnologyHeat shock proteinmedicineHumans030304 developmental biologymedia_commonBiological Products0303 health sciencesbiologyTopoisomeraseDrug Resistance MultipleMultiple drug resistanceDrug Resistance NeoplasmCancer cellCancer researchbiology.proteinEffluxBiotechnologyBiotechnology Advances
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Mitochondrial phylogeography of the edible dormouse (Glis glis) in the western Palearctic region

2010

International audience; This study describes in detail the phylogeoraphic pattern Of the edible dormouse (Glis glis) a European rodent With pronounced hibernating behavior We Used sequences of 831 base pairs of the mitochondrial DNA cytochrome-b gene from 130 edible dormice collected at 43 localities (throughout Its distribution. Our results reveal presence of 3 main haplogroups: Sicilian, South Italian (restricted to the Calabrian region) (a widespread lineage corresponding to all remaining western, central. and eastern European populations). Examination of paleontological data confirms refugial regions for G,Its in the 3 Mediterranean peninsulas, although overall low genetic diversity is …

0106 biological sciencesEUROPEpostglacial colonization[SDV]Life Sciences [q-bio]ZoologyGENETIC CONSEQUENCESmitochondrial DNABiologyphylogeography010603 evolutionary biology01 natural sciencesHaplogroup03 medical and health sciencesRefugium (population biology)biology.animalGeneticsGLACIAL REFUGIAGenetic variabilitydormouse Europe glacial refugia Glis glis mitochondrial DNA phylogeography postglacial colonizationWOODMOUSE APODEMUS-SYLVATICUSDormouseMAXIMUM-LIKELIHOODEcology Evolution Behavior and Systematics030304 developmental biologyNature and Landscape ConservationEdible dormouse0303 health sciencesGenetic diversityEcologyPOPULATION-GROWTHEcology15. Life on landbiology.organism_classificationDNA-SEQUENCESEastern europeandormousePhylogeographyVOLE MICROTUS-ARVALIS[SDE]Environmental SciencesAnimal Science and ZoologyICE AGESGlis glis
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Fatty acid hydroperoxide lyase of green bell pepper: cloning in Yarrowia lipolytica and biogenesis of volatile aldehydes

2004

Publication Inra prise en compte dans l'analyse bibliométrique des publications scientifiques mondiales sur les Fruits, les Légumes et la Pomme de terre. Période 2000-2012. http://prodinra.inra.fr/record/256699; International audience; Fatty acid hydroperoxide lyase (HPO lyase) is a cytochrome P450 acting on fatty acid hydroperoxides in many organisms. The expression of green bell pepper HPO lyase in the yeast Yarrowia lipolytica is described for the first time. HPO lyase activity from yeast extract and whole yeast cells is measured and aldehydes production from yeast extract and whole yeast cells is compared. 1200 U/L reaction medium were obtained after 96 h of culture on olive oil rich me…

0106 biological sciencesEXPRESSIONBioconversionVOLATILE COMPOUNDSBioengineeringBiology01 natural sciencesApplied Microbiology and BiotechnologyBiochemistryCLONING03 medical and health sciencesSUBSTRATEBiotransformation010608 biotechnologyYeast extractLyase activity030304 developmental biologychemistry.chemical_classificationHYDROPHOBICITY0303 health sciencesBIOCONVERSIONfungiYarrowiabiology.organism_classificationLyaseYeastYARROWIA LIPOLYTICAHYDROPEROXIDE LYASEEnzyme[SDV.MP]Life Sciences [q-bio]/Microbiology and ParasitologychemistryBiochemistryWHOLE CELLSFATTY ACIDBiotechnology
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Predators' consumption of unpalatable prey does not vary as a function of bitter taste perception

2020

Many prey species contain defensive chemicals that are described as tasting bitter. Bitter taste perception is, therefore, assumed to be important when predators are learning about prey defenses. However, it is not known how individuals differ in their response to bitter taste, and how this influences their foraging decisions. We conducted taste perception assays in which wild-caught great tits (Parus major) were given water with increasing concentrations of bitter-tasting chloroquine diphosphate until they showed an aversive response to bitter taste. This response threshold was found to vary considerably among individuals, ranging from chloroquine concentrations of 0.01 mmol/L to 8 mmol/L.…

0106 biological sciencesEXPRESSIONDEFENSEmedia_common.quotation_subjectbitter tasteLibrary scienceConsumption (sociology)BiologySTRATEGIC DECISIONS010603 evolutionary biology01 natural sciencesBasic Behavioral and Social ScienceMONARCH BUTTERFLIES03 medical and health sciencesREPERTOIREBitter taste perceptionchemical defenseAvoidance learningExcellenceFOODBehavioral and Social ScienceaposematismDental/Oral and Craniofacial DiseaseEcology Evolution Behavior and SystematicsEDUCATED PREDATORS030304 developmental biologyIndependent researchmedia_commonNutrition0303 health sciencesBIRDSFOS: Clinical medicine3103 EcologyNeurosciencestoxinsBitter tastehumanitiesEVOLUTIONgreat titsRECEPTORS3109 ZoologyResearch councilavoidance learning1181 Ecology evolutionary biologybehavior and behavior mechanismsAnimal Science and Zoology31 Biological Sciences
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Differential recovery of habitat use by birds after wind farm installation: A multi-year comparison

2017

Abstract Onshore wind farms remain one of the most widely used technologies for the production of renewable energy. These are known to affect birds through disturbance or collision. Most research focus on the impact of wind farms on raptors or other large bird species, especially those of conservation concern. However, limited information exists on the effect of wind farms on small birds. Recovery of large versus small bird populations impacted by wind farms is also largely unstudied. A reason for this is the lack of long-term datasets based on standardized, systematic assessments. We monitored birds in the vicinity of a wind farm in an upland habitat in southern Spain (Malaga province), im…

0106 biological sciencesEcologyImpact assessmentbusiness.industryEcology010604 marine biology & hydrobiologyGeography Planning and DevelopmentWildlifeManagement Monitoring Policy and Law010603 evolutionary biology01 natural sciencesRenewable energyFisheryGeographyHabitatDisturbance (ecology)Abundance (ecology)Sea breezeEnvironmental impact assessmentbusiness
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The roles of temperature, nest predators and information parasites for geographical variation in egg covering behaviour of tits (Paridae)

2020

Abstract Aim: Nest building is widespread among animals. Nests may provide receptacles for eggs, developing offspring and the parents, and protect them from adverse environmental conditions. Nests may also indicate the quality of the territory and its owner and can be considered as an extended phenotype of its builder(s). Nests may, thus, function as a sexual and social signal. Here, we examined ecological and abiotic factors—temperature, nest predation and interspecific information utilization—shaping geographical variation in a specific nest structure—hair and feather cover of eggs—and its function as an extended phenotype before incubation in great (Parus major) and blue tits (Cyanistes …

0106 biological sciencesEconomicsBiology010603 evolutionary biology01 natural sciencesPredation03 medical and health sciencesCyanistes caeruleusNestbird nestParus majorBiologyEcology Evolution Behavior and SystematicsComputingMilieux_MISCELLANEOUS030304 developmental biology0303 health sciencesbreeding successEcologyOcellsEcologyextended phenotype15. Life on landBird nestChemistryVariation (linguistics)[SDE]Environmental Sciencesnest structure
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Combining molecular microbial ecology with ecophysiology and plant genetics for a better understanding of plant-microbial communities' interactions i…

2013

18 pages; International audience

0106 biological sciencesEcophysiologyquantitative geneticsecophysiologyPlant genetics[ SDV.SA.SDS ] Life Sciences [q-bio]/Agricultural sciences/Soil studyBiology[SDV.SA.SDS]Life Sciences [q-bio]/Agricultural sciences/Soil study01 natural sciences03 medical and health sciencesplant–microbes interactionsMicrobial ecologyBotany[ SDV.EE.IEO ] Life Sciences [q-bio]/Ecology environment/SymbiosisComputingMilieux_MISCELLANEOUS030304 developmental biology2. Zero hunger0303 health sciencesRhizosphere[ SDE.BE ] Environmental Sciences/Biodiversity and EcologyEcologymodelingQuantitative geneticsMicrobial population biology[SDE.BE]Environmental Sciences/Biodiversity and Ecologymicrobial communityrhizosphere010606 plant biology & botany[SDV.EE.IEO]Life Sciences [q-bio]/Ecology environment/Symbiosis
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ABP1 Mediates Auxin Inhibition of Clathrin-Dependent Endocytosis in Arabidopsis

2010

SummarySpatial distribution of the plant hormone auxin regulates multiple aspects of plant development. These self-regulating auxin gradients are established by the action of PIN auxin transporters, whose activity is regulated by their constitutive cycling between the plasma membrane and endosomes. Here, we show that auxin signaling by the auxin receptor AUXIN-BINDING PROTEIN 1 (ABP1) inhibits the clathrin-mediated internalization of PIN proteins. ABP1 acts as a positive factor in clathrin recruitment to the plasma membrane, thereby promoting endocytosis. Auxin binding to ABP1 interferes with this action and leads to the inhibition of clathrin-mediated endocytosis. Our study demonstrates th…

0106 biological sciencesEndosomemedia_common.quotation_subjectArabidopsisReceptors Cell SurfaceEndocytosis01 natural sciencesClathrinGeneral Biochemistry Genetics and Molecular BiologyArticle03 medical and health sciencesAuxinheterocyclic compoundsPIN proteinsInternalization030304 developmental biologymedia_commonPlant Proteinschemistry.chemical_classificationAuxin binding0303 health sciencesbiologyIndoleacetic AcidsBiochemistry Genetics and Molecular Biology(all)Arabidopsis ProteinsCell MembranefungiMembrane Transport Proteinsfood and beveragesReceptor-mediated endocytosisClathrinEndocytosisCell biologychemistrybiology.protein010606 plant biology & botanyCell
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Toward reconstructing the evolution of advanced moths and butterflies (Lepidoptera: Ditrysia): an initial molecular study

2009

AbstractBackgroundIn the mega-diverse insect order Lepidoptera (butterflies and moths; 165,000 described species), deeper relationships are little understood within the clade Ditrysia, to which 98% of the species belong. To begin addressing this problem, we tested the ability of five protein-coding nuclear genes (6.7 kb total), and character subsets therein, to resolve relationships among 123 species representing 27 (of 33) superfamilies and 55 (of 100) families of Ditrysia under maximum likelihood analysis.ResultsOur trees show broad concordance with previous morphological hypotheses of ditrysian phylogeny, although most relationships among superfamilies are weakly supported. There are als…

0106 biological sciencesEntomologyNuclear geneUNESCO::CIENCIAS DE LA VIDA::Biología animal (Zoología) ::InvertebradosEvolutionmedia_common.quotation_subjectInitial molecular studyZoologyInsect010603 evolutionary biology01 natural sciencesProtein-coding nuclear genesLepidoptera genitaliaLepidoptera; Protein-coding nuclear genes; Initial molecular study03 medical and health sciencesDitrysiaPhylogenetics:CIENCIAS DE LA VIDA::Biología animal (Zoología) ::Invertebrados [UNESCO]Research articleQH359-425AnimalsCladeEcology Evolution Behavior and SystematicsPhylogeny030304 developmental biologymedia_common0303 health sciencesbiologyBayes TheoremSequence Analysis DNAbiology.organism_classificationBiological EvolutionLepidopteraEvolutionary biologyBombycoideaBMC Evolutionary Biology
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