Search results for "Development"
showing 10 items of 26949 documents
Nivolumab Enhances In Vitro Effector Functions of PD-1+ T-Lymphocytes and Leishmania-Infected Human Myeloid Cells in a Host Cell-Dependent Manner
2017
Functional impairment of T-cells and a concomitant augmented expression of programmed death-1 (PD-1) have been observed in visceral leishmaniasis patients, as well as in experimental models for visceral and cutaneous leishmaniasis. The PD-1/PD-1-ligand (PD-1/PD-L) interaction negatively regulates T-cell effector functions, which are required for parasite control during leishmaniasis. The aim of this study was to elucidate the impact of the PD-1/PD-L axis in a human primary in vitro infection model of Leishmania major (Lm). Blocking the PD-1/PD-L interaction with nivolumab increased T-cell proliferation and release of the proinflammatory cytokines TNFα and IFNγ during the cocultivation of Lm…
Relationships between peer violence and child to parent violence
2018
[EN] Peer violence and child to parent violence are two current problems that have serious psychosocial consequences for both victims and perpetrators. Despite their incidence and severity during the adolescence, few studies have explored the possible relationships between both types of violence. Thus, the aim of the present study was to explore these relationships, comparing peer violence, both manifest (direct) and relational (indirect) aggressions, in adolescents with problems of child to parent violence and adolescents who do not exercise child to parent violence. 66 adolescents living in two juvenile re-education centers for reasons of child to parent violence and another 66 secondary …
De yngste barna og tingene deres – en ANT-analyse av lek i småbarnsavdelinger
2017
Artikkelen presenterer en mikro-etnografisk undersøkelse av barns forhold til tingene i to småbarnsavdelinger i norske barnehager. Hensikten er å forstå hvordan barns relasjoner til ting virker inn på deres mulighet til deltagelse og sosial posisjonering i gruppen. Undersøkelsen er basert på Aktør-Nettverk-Teori som vektlegger tingenes betydning som agens i sosiale nettverk og tingenes funksjon som forlengelse av barnas kropper. Undersøkelsen viser at tingene har betydning som legitim inngangsbillett til deltagelse i lekegrupper og at tingenes innbyrdes hierarkiske orden bidrar i å uttrykke den sosiale orden mellom barna som inngår i relasjon med dem. The article presents a micro-ethnograph…
Localizing SDGs through Development Education. The Experience of the Valencian City Strategy
2019
[ES] Este artículo presenta la propuesta de Educación para el Desarrollo que se recoge en la Estrategia para la Educación no formal de la ciudad de Valencia y su relación con los Objetivos de Desarrollo Sostenible (ODS). El contenido de la Estrategia se basa en tres ejes fundamentales: 1) un enfoque territorial en el barrio o distrito; 2) la importancia de la coordinación entre actores municipales y las ONGD para desarrollar las propuestas educativas y 3) una serie de temáticas y metodologías prioritarias. La correspondencia de la Estrategia con los ODS ha sido interpretada empleando un marco de análisis pensado para la innovación transformadora. Esta interpretación distingue entre ODS que …
Adolescents' perception of scientific inquiry in nature : a drawing analysis
2019
This study was carried out to determine adolescents’ perception of scientific inquiry (SI) in nature and the effect of a science camp on those perceptions. Eleven science campers (14 to 16 years old) participated in this research during a science camp. Pre- and post-test included open questions and drawing tasks. The campers’ drawings were analyzed to assess their out-of-school perceptions related to SI. The aim was to clarify what phases and factors the campers associated with SI in nature, and how their perceptions differ after participating at a science camp. The findings suggest that the phases of SI were well known before the camp, but minor developments in campers’ perceptions of the …
Corrigendum: Data practices and inequality in South African early childhood development policy: Technocratic management versus social transformation
2019
No abstract available.
Access-Awareness-Agency (AAA) Model of Music-Based Social-Emotional Competence (MuSEC)
2019
Social–emotional competence (SEC) is a set of psychological resources, highly relevant for adaptive growth and wellbeing. Music has been argued to support social–emotional skills, yet there is little theoretical consensus about the underlying impact mechanisms and the special nature of music as a medium for SEC. This article presents a theoretical model of music-based SEC that combines research from general SEC models with music-specific literature from music psychology, music education, music therapy, and music for health and wellbeing. The proposed access-awareness-agency (AAA) model defines music-based social–emotional competence (MuSEC) as interplay of embodied access, reflective awaren…
The Test–Retest Repeatability of a Rhythm Coordination Test Procedure in 4- to 6-Year-Old Children : A Pilot Study
2020
Moving to music combines the ability of rhythm and coordination. In relation to the musical and motor development of children, sensorimotor synchronization requires the ability to perceive and perform a steady beat. The present pilot study aimed to investigate the test–retest repeatability of a rhythm coordination test procedure in order to pilot the procedure for children. Test–retest repeatability reflects the variation in measurements taken by the rhythm coordination test on the same participant under the same conditions. Ten children (mean age 5.5 years, standard deviation (SD) 0.6) participated in the tests. The test performance was evaluated in points from 0 to 8, separately at a slow…
Towards a framework for New Service Development Practices
2017
Different frameworks for New Service Development (NSD) practices have been suggested by prior conceptual research. We have assessed three frameworks frequently referred to in extant research, and exposed how these three cover different dimensions of NSD practices. By exploring the practices of NSD empirically, this paper continues the ongoing discussion of what the relevant aggregated dimensions of NSD practices are. The detailed practices identified by interviewing 25 employees, all with key roles in relation to NSD in five large Scandinavian service firms, about their NSD practices, are clustered into three aggregated overarching dimensions of NSD practices: 1) identifying needs, 2) assur…
Regenerative Medicine as an Emergent Cluster in Tampere Region
2015
[EN]: Clusters are important for regional economies and emergent clusters are in a key position, as a means of adding more diversification to the current economic activity by involving new technologies and industries. Science-based industries may be the most promising in this regard since they are encouraged to develop and enhance the economic imaginaries of territories under the umbrella of radical innovations or in the name of broadening the current economic model based on mostly traditional industries. Regenerative medicine (RM) could be an example of these so-called emergent clusters. Regenerative medicine is highly dependent on academic research, which means that local territories must…