Search results for "Development"

Growth and differentiation factor 11 (GDF11): Functions in the regulation of erythropoiesis and cardiac regeneration

2015

International audience; Members of the TGF-β superfamily transduce their signals through type I and II receptor serine/threonine kinases. The binding of activins to activin type IIA (ActRIIA) or type IIB (ActRIIB) receptors induces the recruitment and phosphorylation of an activin type I receptor (ALK4 and/or ALK7), which then phosphorylates the Smad2 and Smad3 intracellular signaling proteins. The regulation of members of the TGF-β family is known to be complex, because many proteins able to bind the ligands and inhibit their activities have been identified. Growth and differentiation factor 11 (Gdf11) belongs to the TGF-β family. GDF11, like other members of the TGF-β superfamily, is prod…

Efficacy of the portage early intervention programme ‘growing: birth to three’ for children born prematurely

2020

Findings are presented from a study examining the effects of the home-based intervention ‘Growing: Birth to Three’ (GBT) on children born prematurely at a regional hospital in Norway over a four-year period. Nineteen children received the intervention, while 17 children comprised the control group. Results indicate that GBT had a positive effect on development at 18 months, as measured by the Bayley Scale of Infant Development. However, by 36 months both the intervention and control groups were in the normal range on this measure. A post-test comparison of language performance at 36 months found significantly higher expressive language scores among children in the intervention group on the …

Dual task cost in balance control and stability in children from 4–7 years old

2019

This study analyzed the development of postural control and the cost of the cognitive task on postural control in the bipedal standing position during childhood. Sixty-six normally developed childr...

Assessing Victim-Blaming Attitudes in Cases of Intimate Partner Violence against Women: Development and Validation of the VB-IPVAW Scale

2018

ABSTRACT Intimate partner violence against women (IPVAW) is the most common form of violence suffered by women and constitutes a serious public health problem of global proportions. Public attitudes towards IPVAW are key to understanding the social context in which this type of violence occurs. Victim-blaming attitudes are among those that reflect public tolerance and acceptability of IPVAW and are often used to explain or justify IPVAW. In this study we develop and validate a new instrument to assess victim-blaming attitudes in cases of IPVAW. A sample of 1,800 participants was recruited through social media and a second sample of 50 IPVAW offenders was used for validation purposes. Throug…

Forms of Bullying and Associations Between School Perceptions and Being Bullied Among Finnish Secondary School Students Aged 13 and 15

2019

AbstractThe study aimed to examine the extent to which Finnish secondary school students experience bullying, how they are bullied, and whether being bullied is associated with school perceptions. The analyses were based on data from the Finnish part of the international Health Behaviour in School-aged Children (HBSC) study, and were obtained from 4262 students aged 13 and 15. The sample was nationally representative. Logistic regression analysis was performed to identify the associations between school perceptions and being bullied. Younger students reported being bullied more often than older students. Among younger students, boys were more often bullied than girls of the same age. There …

Effects of a cognitive-behavioral intervention program on the health of caregivers of people with autism spectrum disorder

2015

AbstractCaregivers of people with autism spectrum disorder (ASD) are chronically exposed to high levels of stress. In turn, such stress is associated with high rates of negative health outcomes. However, few studies have analyzed the effects of psychotherapeutic interventions in improving health in this population. The main aim of the present study was to evaluate the effectiveness of a cognitive-behavioral intervention program, based on the model proposed by Ruiz-Robledillo and Moya-Albiol (2014a). For this, we used a sample of 17 informal caregivers of people diagnosed with ASD. The study was based on a pre-post design. Caregivers had lower levels of burden immediately after the intervent…

Human values and retirement experiences: A longitudinal analysis of Norwegian data.

2021

Motivational factors, such as one’s value system, may affect how people cope with the opportunities and challenges of retirement. This article explores the moderating roles of Schwartz’s four basic values (self-enhancement, self-transcendence, openness to change, and conservation) on the magnitude and duration of retirement effects on life satisfaction between two waves (2007 and 2017) of the Norwegian Life course, Ageing and Generation (NorLAG) study. Fixed-effect regression analyses are run separately for men and women to account for gender differences in the attachments and identities tied to work and non-work domains. Retirement is not a uniform experience, and findings show that retire…

Four tasks for forward-looking global ethics

2014

Our challenge for the twenty-first century consists in showing how to construct a global ethics and in trying to discover a rational foundation for it, which may be used as guidance for action and as a norm for the criticism of specific situations. I argue that four tasks must be accomplished to construct a global ethics: (1) Construct that global governance or that world government that makes cosmopolitan citizenship possible. (2) Foster the joint work of bioethics, economic and business ethics, and development ethics – areas of applied ethics, each one of which on its own has reached the global level. (3) Discover a rational basis for a global ethics, which has a universal normative force…

Erratum to: Socio-Demographic Vulnerability: The Condition of Italian Young People

2010

Disconnected Lives: Trends in Time Spent Alone in Finland

2020

AbstractDiscussions about social isolation have been extensive over the past few decades. A less sociable nature of social ties has been identified in Western societies. The phenomenon has been associated with demographic changes such as aging and living alone as well as changes in the use of new technologies. In this study we employ representative Finnish Time Use Surveys from three decades, 1987–1988 (n = 1887), 1999–2000 (n = 2673) and 2009–2010 (n = 1887) to examine the trends in social isolation, measured as time spent alone. Our results showed that between 1987 and 2010 the time spent alone increased by 124 min per day. The increase was linear and occurred in nearly all population gro…