Search results for "Development"
showing 10 items of 26949 documents
A SUMOylation-defective MITF germline mutation predisposes to melanoma and renal carcinoma
2011
International audience; So far, no common environmental and/or phenotypic factor has been associated with melanoma and renal cell carcinoma (RCC). The known risk factors for melanoma include sun exposure, pigmentation and nevus phenotypes; risk factors associated with RCC include smoking, obesity and hypertension. A recent study of coexisting melanoma and RCC in the same patients supports a genetic predisposition underlying the association between these two cancers. The microphthalmia-associated transcription factor (MITF) has been proposed to act as a melanoma oncogene; it also stimulates the transcription of hypoxia inducible factor (HIF1A), the pathway of which is targeted by kidney canc…
A genomic reappraisal of symbiotic function in the aphid/Buchnera symbiosis: reduced transporter sets and variable membrane organisations.
2011
International audience; Buchnera aphidicola is an obligate symbiotic bacterium that sustains the physiology of aphids by complementing their exclusive phloem sap diet. In this study, we reappraised the transport function of different Buchnera strains, from the aphids Acyrthosiphon pisum, Schizaphis graminum, Baizongia pistaciae and Cinara cedri, using the re-annotation of their transmembrane proteins coupled with an exploration of their metabolic networks. Although metabolic analyses revealed high interdependencies between the host and the bacteria, we demonstrate here that transport in Buchnera is assured by low transporter diversity, when compared to free-living bacteria, being mostly bas…
A person-oriented approach to diary data. Children’s temperamental negative emotionality increases susceptibility to emotion transmission in father-c…
2015
The notion that some individuals are more prone to emotion transmission than others has prompted the need for a person-oriented approach to emotion transmission in parent-child dyads. The present study applied a person-oriented analysis to examine the patterns of emotion transmission that can be identified in the diary data of father-child dyads, and the extent to which children with high levels of temperamental negative emotionality are particularly susceptible to emotion transmission within the family. Mothers of 149 first grade children (age 6 to 7) completed questionnaires concerning their child’s temperament. Mothers and fathers maintained diary questionnaires (for a total of 7 days) c…
Professional agency in a university context: Academic freedom and fetters
2020
Professional agency is an urgent topic in academic contexts, albeit relatively unexplored, and elaborated with contradictory conclusions on its extent and characteristics. To contribute to the discussion, this multimethod study investigated professional agency within a Finnish university. We utilised questionnaire data and interviews to explore agency, as manifested in influencing at work, developing work practices, and negotiating professional identity. We found that overall, these three dimensions of agency were manifested fairly substantially, and in a similar manner among the academic staff. The study further emphasises the social nature of professional agency, and presents theoretical …
Crecimiento inicial de Eugenia stipitata, Inga spectabilis e Inga edulis en Napo, Ecuador
2018
Agriculture has been one of the causes of deforestation, causing environmental impact and soil degeneration, which leads to lower income earned by farmers; hence the need to implement agroforestry systems .This research aims to describe fromthe initial growth of Eugenia stipitata, Inga edulis, and Inga spectabilis to 320 days after emergence. The study took place at the Amazon Research and Conservation Center of the Amazonas State University, during 2014 and 2015. The growth process was evaluated in regards to plant height, stem diameter, number of leaves, and branch length. Plant height and stem diameter were compared over time applying variance analysis. Precipitation was also compared to…
‘Because I point to myself as the hog’ : interactional achievement of moral decisions in a classroom
2016
Abstract Drawing on the conversation analytic and sociocultural perspectives, this study investigates children's situated moral negotiations in classroom peer interaction in the absence of a teacher. The conversation analytic methodology is used to operationalise some of the key elements of the sociocultural perspective on moral development. In this way, this study enables readers to observe and study the semiotic, conversational and interactional mediations of moral functioning in real life, with the example of children's moral practices. The empirical analysis is based on video-recorded sequences in which primary school children work with the rules of a counting rhyme which is banned by t…
Predicting Earthquake-Induced Landslides by Using a Stochastic Modeling Approach: A Case Study of the 2001 El Salvador Coseismic Landslides
2023
In January and February 2001, El Salvador was hit by two strong earthquakes that triggered thousands of landslides, causing 1259 fatalities and extensive damage. The analysis of aerial and SPOT-4 satellite images allowed us to map 6491 coseismic landslides, mainly debris slides and flows that occurred in volcanic epiclastites and pyroclastites. Four different multivariate adaptive regression splines (MARS) models were produced using different predictors and landslide inventories which contain slope failures triggered by an extreme rainfall event in 2009 and those induced by the earthquakes of 2001. In a predictive analysis, three validation scenarios were employed: the first and the second …
Spatial Cognition 2020/1: Book of abstracts : August 2-4, 2021, University of Latvia
2021
Spatial Cognition is concerned with the acquisition, development, representation, organization, and use of knowledge about spatial objects in real, virtual or hybrid environments and processed by human or artificial agents. Spatial Cognition includes research from different fields insofar as they are concerned with cognitive agents and space, such as cognitive and developmental psychology, linguistics, computer science, geography, cartography, philosophy, neuroscience, and education. Research issues in the field range from the investigation of human spatial cognition to mobile robot navigation, including topics such as wayfinding, spatial planning, spatial learning, internal and external re…
Hydrothermal liquefaction of wet waste biomass: a practical assessment to achieve an integral valorization of municipal sludge
2020
Hydrothermal liquefaction of municipal sludge was conducted to perform a practical assessment to achieve an integral valorization of this wet waste biomass. Experiments were done to investigate the effects of sub- and supercritical water and of the fluid dynamic regime on the energy recovery of the process and on the quality of the products. Experimental runs were performed at two different temperatures (350°C and 400°C) changing reaction time in order to work at the same kinetic severity of the process (LogR0=8.9, calculated as in ref. [3]). An improvement of the C % in the solid residues and of the ration of H/C of the biocrude was obtained when stirred reactor was used both in sub- and s…
The Assessment of Well-being in Context of Regional Development
2014
The aim of the paper is to present the methodology and results of some empirical research of the assessment of well-being at local level in context of regional development. To achieve the aim, such qualitative and quantitative methods of research as comparing, grouping, graphical analysis and focus group methods were be used. The main result and finding of the paper is the conclusion that in order to promote the regional development of the territory, the assessment of well-being at the level of administrative territory is needed. Based on this assessment, the policy can be developed in order to promote the regional development and social cohesion of the territory, as well as to have better …